Md. Motiur Rahman - Academia.edu (original) (raw)
Papers by Md. Motiur Rahman
Institute of Developing Economies eBooks, 1996
PLOS Genetics, Jun 20, 2013
The sphingolipid ceramide elicits several stress responses, however, organisms survive despite in... more The sphingolipid ceramide elicits several stress responses, however, organisms survive despite increased ceramide but how they do so is poorly understood. We demonstrate here that the AKT/FOXO pathway regulates survival in increased ceramide environment by metabolic adaptation involving changes in glycolysis and lipolysis through novel downstream targets. We show that ceramide kinase mutants accumulate ceramide and this leads to reduction in energy levels due to compromised oxidative phosphorylation. Mutants show increased activation of Akt and a consequent decrease in FOXO levels. These changes lead to enhanced glycolysis by upregulating the activity of phosphoglyceromutase, enolase, pyruvate kinase, and lactate dehydrogenase to provide energy. A second major consequence of AKT/FOXO reprogramming in the mutants is the increased mobilization of lipid from the gut through novel lipase targets, CG8093 and CG6277 for energy contribution. Ubiquitous reduction of these targets by knockdown experiments results in semi or total lethality of the mutants, demonstrating the importance of activating them. The efficiency of these adaptive mechanisms decreases with age and leads to reduction in adult life span of the mutants. In particular, mutants develop cardiac dysfunction with age, likely reflecting the high energy requirement of a well-functioning heart. The lipases also regulate physiological triacylglycerol homeostasis and are important for energy metabolism since midgut specific reduction of them in wild type flies results in increased sensitivity to starvation and accumulation of triglycerides leading to cardiac defects. The central findings of increased AKT activation, decreased FOXO level and activation of phosphoglyceromutase and pyruvate kinase are also observed in mice heterozygous for ceramide transfer protein suggesting a conserved role of this pathway in mammals. These data reveal novel glycolytic and non-autonomous lipolytic pathways in response to increased ceramide for sustenance of high energy demanding organ functions like the heart.
Open heart, Sep 1, 2020
Real-world characteristics and readmissions among patients undergoing ablation for ventricular ta... more Real-world characteristics and readmissions among patients undergoing ablation for ventricular tachycardia: a retrospective database analysis of commercially insured patients in the USA.
Blood, Nov 5, 2021
Background: Despite the development of highly active novel agents, high risk (HR) multiple myelom... more Background: Despite the development of highly active novel agents, high risk (HR) multiple myeloma (MM) patients continue to demonstrate relatively poor prognosis. Limited data is published on how treatment patterns with risk stratification systems have changed over time. Moreover, real world studies using electronic health records (EHRs) have not evaluated the performance of risk stratification systems with real world outcomes. This study aims to evaluate the ability to implement three different risk stratification systems - international staging system (ISS), revised ISS (R-ISS), and high-risk chromosomal abnormalities (HRCA, defined as presence of del(17)p, t(4;14) and/or t(4;16)) [Palumbo et al. 2015] - to characterize treatment patterns and associated outcomes [real world overall survival (rwOS) and real world progression free survival (rwPFS)] among newly diagnosed MM (NDMM) patients in the US community practice. Methods: This study used Flatiron Enhanced MM EHR de-identified database (New York, NY). Newly diagnosed MM patients (≥ 18 years) were diagnosed from January 2015 through June 2020 (cohort 1 - for studying treatment distribution) with follow-up through December 2020, and from January 2015 through December 2018 (cohort 2 - for rwOS and rwPFS), with follow-up through December 2020. Patients with malignancies other than MM were excluded. Proportion of rwOS was measured from treatment initiation until death, and median rwPFS was measured from treatment initiation until death, progression, or start of new line of therapy using Kaplan-Meier method. Results: A total of 1,979 and 1,382 patients were eligible in cohorts 1 and 2, respectively. In both the cohorts, approximately 18% (cohort 1: N=367, cohort 2: N=248), 41% (cohort 1: N=805, cohort 2: N=566), and 37% (cohort 1: N=738, cohort 2: N=508) were HR patients according to the R-ISS, ISS, and HRCA criteria, respectively. Approximately half of the HR patients were ≥70 years old (52% for R-ISS III and ISS III, and 47% for HRCA), with chronic kidney disease stage ≥3 by eGFR for 54% R-ISS III and ISS III, and 34% high risk CA, and ECOG score ≥2 for 18% R-ISS III, 19% ISS III, and 14% HRCA patients. Triplets were the most frequent treatment regimens (62% for R-ISS III and II, and 66% for R-ISS I; 59% for ISS III, and 65% for ISS II and I; 65% for HRCA and 61% for standard risk CA(SRCA) with proteasome inhibitors (PIs) / immunomodulatory agents (IMiDs) / dexamethasone being most common regimen across all the risk stratification criteria. Quadruplet agent use was higher in R-ISS III and ISS III categories (6.8% vs. 3.3% for R-ISS III vs. I; 6.3% vs. 2.8% for ISS III vs. I). The median rwPFS in HR patients were shorter than the lower risk subgroups (R-ISS III: 8.8 months [95% CI 7.1 - 11.0], R-ISS II: 12.1 months [95% CI 10.7 - 13.6], R-ISS I: 23.5 months [95% CI 13.8 - .]; ISS III: 10.4 months [95% CI 8.5 - 11.5], ISS II: 12.7 months [95% CI 10.7 - 14.3], ISS I: 16 months [95% CI 12.2 - 19.5]; HRCA: 10.1 months [95% CI 8.8 - 12.1], SRCA: 13.1 months [95% CI 11.3 - 14.8]). The 2-year rwOS was lower in the HR subgroups (R-ISS III: 0.65 [95% CI 0.59 - 0.70], R-ISS II: 0.79 [95% CI 0.76 - 0.81], R-ISS I: 0.91 [95% CI 0.85 - 0.95]; ISS III: 0.68 [95% CI 0.64 - 0.72], ISS II: 0.81 [95% CI 0.77 - 0.84], ISS I: 0.89 [95% CI 0.85 - 0.92]; HRCA: 0.75 [95% CI 0.71 - 0.79], SRCA: 0.79 [95% CI 0.76 - 0.81]). Discussion: This study found that median rwPFS and 2-year rwOS proportions were consistently lower among HR patients compared to the standard risk individuals. The majority of the HR patients were older, with decreased levels of physical functioning and worse indicators of end-organ damage including renal function, anemia, and hypercalcemia. Most patients received triplets with frequent use of PIs likely for aggressive disease control among HR patients. Some HR patients received more quads than lower risk patients suggesting treatment intensification, but HR patients also received stem cell transplants at a lower rate. Although a smaller proportion of patients have all the data collected needed for R-ISS classification, the consistent findings across treatment outcomes suggest that R-ISS is implementable in real world studies and has a greater discriminatory ability than ISS or HRCA alone. Overall, this study suggests that HR patients have relatively poor outcomes which calls for the study of risk-adapted implementation of novel therapies among this patient population in the US community practice settings. Figure 1 Figure 1. Rahman: Amgen Inc.: Current Employment, Current holder of stock options in a privately-held company. Kim: Amgen: Current Employment, Current equity holder in publicly-traded company. Mateus: Amgen Inc.: Current Employment, Other: Work at Amgen as a contract employee through DOCS. Keegan: Amgen Inc.: Current Employment, Current holder of stock options in a privately-held company.
Routledge eBooks, Dec 23, 2008
Routledge studies in development economics, Dec 23, 2008
Recently by using contamination families, a new way of modeling dependence has been introduced. I... more Recently by using contamination families, a new way of modeling dependence has been introduced. In this method, a sequence of parametric copulas is considered and in a few numbers of steps, accurate approximations for copula densities are obtained. By using the selection model method, the model complexity and number of model parameters are balanced. In this paper, two main variables in Iranian Household Income and Expenditure survey are considered and a copula density for those variables is estimated by using contamination family and selection model method.
Infection is a multistep process including adhesion, colonisation, invasion and multiplication wh... more Infection is a multistep process including adhesion, colonisation, invasion and multiplication which finally results in disease. Bacterial surface components and virulence factors are essential for all these different steps and they are co-ordinately regulated during the different steps of pathogenesis and infection. Host factors like the mucosal barrier, complement, phagocytosis, humoral and cellular immune response result in either elimination of pathogen or, if they fail to protect the body, progress of the disease process. LPS is an indispensable surface component and important virulence factor of gram- negative bacteria. The antibody response against different LPS serotypes of M. catarrhalis was studied in hyperimmune rabbit sera and a predominant serotype specific antibody response was observed. On the other hand, in the human host, humoral immune response was mainly observed against the common inner core region of the LPS. Immunochemical characterization of LPS epitopes by monoclonal antibodies confirmed the presence of a Gal-alpha-(1-4)-Gal epitope in the LPS of M. catarrhalis which is in agreement with the chemical structure of M. catarrhalis LPS. The humoral immune response against major outer membrane proteins was also studied in paired sera from patients suffering from a respiratory tract infection caused by M. catarrhalis. Titre rise in specific IgG 1, IgG2 and IgG3 was observed in most of the patients. Optimal sensitivity was obtained by using the OMP as antigen and testing for a rise of IgG3 antibodies. A good correlation was observed between total immunoglobulin response and IgG3 response. PilC, a 110 kD pilus associated protein was studied for function and localization. PilC is expressed from the pilC locus and N. meningitidis FAM20 expresses two PilC proteins, PilC 1 and PilC2 encoded by pilC1 and pilC2. PilC 1 and pilC2 are highly homologous but not identical. PilC1 and PilC2 share 84.7% similarity and 74.5% identity. PilC1 or PilC2 or both are essential for pilus biogenesis since pilC1-, pilC2- mutants were nonpiliated. In N. meningitidis, expression of PilC1, but not PilC2, contributes to attachment to host cells. Immunogold electron microscopy of cryosections and whole piliated bacteria indicated that PilC is located in the outer membrane and at the base of the pili. Key words: Moraxella catarrhalis/antibody/ LPS/ Neisseria/pili/PilC ISBN- 91-628-2314-
Leukemia & Lymphoma, Nov 12, 2022
Routledge eBooks, Dec 23, 2008
Bangladesh Journal of Fisheries
To assess the growth, survival and intactness of mud crabanexperiment was conducted for a period ... more To assess the growth, survival and intactness of mud crabanexperiment was conducted for a period of 120 days from July to October 2021 in the farmers ponds of Betbunia village under Paikgacha upazilla at Khulna Districts, Bangladesh. The crab Juvenile was collected from adjacent Shibsha River and stocked in a pond of 0.01 ha area with the stocking density at 1 m2,2m2, 3 m2in T1,T2 and T3 treatments with 2 replications each. Fresh choppedtilapiafish was fed and the feed was adjusted periodically in accordance with the growth performance. Production and physico-chemical parameters were recorded and analyzed according to standard methodsduring the culture period. Among these parameters salinity has significant (p<0.05) role on survival of mud crab.After 120 days of rearing, obtained average final weight was 97.8±13.86g, 94.22±9.25gand 117.77±14.34g; with the estimated yield of 371.56 kg/ha, 433.12 kg/ha and 376.56 kg/ha, survival was 38%, 46% and 32% in T1, T2 and T3 treatments resp...
The main concern of this paper is to examine the food availability, self-sufficiency rate and foo... more The main concern of this paper is to examine the food availability, self-sufficiency rate and food gap situation in Bangladesh. Attempt has been made to estimate food gaps between production and requirement for the last thirteen years. Future productions of rice and wheat have been forecasted by using appropriate econometric methods such as ARIMA and Holt's linear smoothing parameter approach. Forecasting of future food grain availability, food grain requirement and food gaps between production and requirement from 2010/11 to 2015/16 has been made. Finally some recommendations which would be helpful for improving the food security situation in Bangladesh have been suggested.
Segmentation on Computed Tomography (CT) image of heart and brain can be optimally posed as Bayes... more Segmentation on Computed Tomography (CT) image of heart and brain can be optimally posed as Bayesian labeling in which the segment of a image is defined as the maximum a posteriori (MAP) probability estimate of the true labeling. The Simulated Annealing (SA) algorithm is used to minimize the energy function associated with MRF posterior distribution function. The goal of this thesis paper is to minimize the energy function using Gaussian distribution and get accurate segmentation by slowly minimize the energy and simultaneously reduce the pixels which have no impact on the image at rapid rate to get the segmentation quickly without degrade the image. The propose algorithm able to get more precise segmentation.
Routledge Studies in Development Economics, 2008
Government gave compensation for such deaths. The death of sheep and goats are mainly due to 'Blu... more Government gave compensation for such deaths. The death of sheep and goats are mainly due to 'Blue Tongue' disease, apart from other diseases. Earter, under Janmabhoomi programme, the cattle-growers were given free medicines twice in a year and there used to be regular medical camps. But, now the Government of A.P. abolished Janmabhoomi programme ...(Interruptions)...And, this is the result of abolition of Janmabhoomi...(Interruptions)..There is also no vaccine to prevent 'Blue tongue' disease. Only now, research started at the National and State level to discover vaccine for this disease. In view of this, I request the Department of Animal Husbandry and the Union Health Ministry to help by way of conducting medical camps.. .(Interruptions)... providing medicines for cattle-growers in A.P. and also advice cattle-growers in A.P. to take precautions when such diseases occur and also request to consider sympathetically for giving compensation to them. Thank you. AN HON. MEMBER: Sir, the point is ...(Interruptions)...We have not abolished the programme...(Interruptions)... SHRIMATI N.P. DURGA: That is what I am saying ...(Interruptions)... Your Government has abolished the Janmabhoomi programme ...(Interruptions)... There are no regular medical camps. MR. CHAIRMAN: Hon. Members, the Constitution (One Hundred and Fourth Amendment) Bill, 2005, as passed by Lok Sabha, is being taken up in the House for consideration and passing. The Bill has to be passed by 2/3rd majority as required under Article 368 of the Constitution. To enable Members to be present at the time of division on various stages of the Bill, the first division on the Bill will be called at 4.30 p.m. If the House agrees, we may dispense with the lunch hour for today. SOME HON. MEMBERS: Agreed. MR. CHAIRMAN: Now, let us take up the Constitution (Amendment) Bill. Mr. Arjun Singh.
International Journal of Computer Applications, 2016
帝京経済学研究 the Teikyo University Economic Review, Mar 1, 2012
Institute of Developing Economies eBooks, 1996
PLOS Genetics, Jun 20, 2013
The sphingolipid ceramide elicits several stress responses, however, organisms survive despite in... more The sphingolipid ceramide elicits several stress responses, however, organisms survive despite increased ceramide but how they do so is poorly understood. We demonstrate here that the AKT/FOXO pathway regulates survival in increased ceramide environment by metabolic adaptation involving changes in glycolysis and lipolysis through novel downstream targets. We show that ceramide kinase mutants accumulate ceramide and this leads to reduction in energy levels due to compromised oxidative phosphorylation. Mutants show increased activation of Akt and a consequent decrease in FOXO levels. These changes lead to enhanced glycolysis by upregulating the activity of phosphoglyceromutase, enolase, pyruvate kinase, and lactate dehydrogenase to provide energy. A second major consequence of AKT/FOXO reprogramming in the mutants is the increased mobilization of lipid from the gut through novel lipase targets, CG8093 and CG6277 for energy contribution. Ubiquitous reduction of these targets by knockdown experiments results in semi or total lethality of the mutants, demonstrating the importance of activating them. The efficiency of these adaptive mechanisms decreases with age and leads to reduction in adult life span of the mutants. In particular, mutants develop cardiac dysfunction with age, likely reflecting the high energy requirement of a well-functioning heart. The lipases also regulate physiological triacylglycerol homeostasis and are important for energy metabolism since midgut specific reduction of them in wild type flies results in increased sensitivity to starvation and accumulation of triglycerides leading to cardiac defects. The central findings of increased AKT activation, decreased FOXO level and activation of phosphoglyceromutase and pyruvate kinase are also observed in mice heterozygous for ceramide transfer protein suggesting a conserved role of this pathway in mammals. These data reveal novel glycolytic and non-autonomous lipolytic pathways in response to increased ceramide for sustenance of high energy demanding organ functions like the heart.
Open heart, Sep 1, 2020
Real-world characteristics and readmissions among patients undergoing ablation for ventricular ta... more Real-world characteristics and readmissions among patients undergoing ablation for ventricular tachycardia: a retrospective database analysis of commercially insured patients in the USA.
Blood, Nov 5, 2021
Background: Despite the development of highly active novel agents, high risk (HR) multiple myelom... more Background: Despite the development of highly active novel agents, high risk (HR) multiple myeloma (MM) patients continue to demonstrate relatively poor prognosis. Limited data is published on how treatment patterns with risk stratification systems have changed over time. Moreover, real world studies using electronic health records (EHRs) have not evaluated the performance of risk stratification systems with real world outcomes. This study aims to evaluate the ability to implement three different risk stratification systems - international staging system (ISS), revised ISS (R-ISS), and high-risk chromosomal abnormalities (HRCA, defined as presence of del(17)p, t(4;14) and/or t(4;16)) [Palumbo et al. 2015] - to characterize treatment patterns and associated outcomes [real world overall survival (rwOS) and real world progression free survival (rwPFS)] among newly diagnosed MM (NDMM) patients in the US community practice. Methods: This study used Flatiron Enhanced MM EHR de-identified database (New York, NY). Newly diagnosed MM patients (≥ 18 years) were diagnosed from January 2015 through June 2020 (cohort 1 - for studying treatment distribution) with follow-up through December 2020, and from January 2015 through December 2018 (cohort 2 - for rwOS and rwPFS), with follow-up through December 2020. Patients with malignancies other than MM were excluded. Proportion of rwOS was measured from treatment initiation until death, and median rwPFS was measured from treatment initiation until death, progression, or start of new line of therapy using Kaplan-Meier method. Results: A total of 1,979 and 1,382 patients were eligible in cohorts 1 and 2, respectively. In both the cohorts, approximately 18% (cohort 1: N=367, cohort 2: N=248), 41% (cohort 1: N=805, cohort 2: N=566), and 37% (cohort 1: N=738, cohort 2: N=508) were HR patients according to the R-ISS, ISS, and HRCA criteria, respectively. Approximately half of the HR patients were ≥70 years old (52% for R-ISS III and ISS III, and 47% for HRCA), with chronic kidney disease stage ≥3 by eGFR for 54% R-ISS III and ISS III, and 34% high risk CA, and ECOG score ≥2 for 18% R-ISS III, 19% ISS III, and 14% HRCA patients. Triplets were the most frequent treatment regimens (62% for R-ISS III and II, and 66% for R-ISS I; 59% for ISS III, and 65% for ISS II and I; 65% for HRCA and 61% for standard risk CA(SRCA) with proteasome inhibitors (PIs) / immunomodulatory agents (IMiDs) / dexamethasone being most common regimen across all the risk stratification criteria. Quadruplet agent use was higher in R-ISS III and ISS III categories (6.8% vs. 3.3% for R-ISS III vs. I; 6.3% vs. 2.8% for ISS III vs. I). The median rwPFS in HR patients were shorter than the lower risk subgroups (R-ISS III: 8.8 months [95% CI 7.1 - 11.0], R-ISS II: 12.1 months [95% CI 10.7 - 13.6], R-ISS I: 23.5 months [95% CI 13.8 - .]; ISS III: 10.4 months [95% CI 8.5 - 11.5], ISS II: 12.7 months [95% CI 10.7 - 14.3], ISS I: 16 months [95% CI 12.2 - 19.5]; HRCA: 10.1 months [95% CI 8.8 - 12.1], SRCA: 13.1 months [95% CI 11.3 - 14.8]). The 2-year rwOS was lower in the HR subgroups (R-ISS III: 0.65 [95% CI 0.59 - 0.70], R-ISS II: 0.79 [95% CI 0.76 - 0.81], R-ISS I: 0.91 [95% CI 0.85 - 0.95]; ISS III: 0.68 [95% CI 0.64 - 0.72], ISS II: 0.81 [95% CI 0.77 - 0.84], ISS I: 0.89 [95% CI 0.85 - 0.92]; HRCA: 0.75 [95% CI 0.71 - 0.79], SRCA: 0.79 [95% CI 0.76 - 0.81]). Discussion: This study found that median rwPFS and 2-year rwOS proportions were consistently lower among HR patients compared to the standard risk individuals. The majority of the HR patients were older, with decreased levels of physical functioning and worse indicators of end-organ damage including renal function, anemia, and hypercalcemia. Most patients received triplets with frequent use of PIs likely for aggressive disease control among HR patients. Some HR patients received more quads than lower risk patients suggesting treatment intensification, but HR patients also received stem cell transplants at a lower rate. Although a smaller proportion of patients have all the data collected needed for R-ISS classification, the consistent findings across treatment outcomes suggest that R-ISS is implementable in real world studies and has a greater discriminatory ability than ISS or HRCA alone. Overall, this study suggests that HR patients have relatively poor outcomes which calls for the study of risk-adapted implementation of novel therapies among this patient population in the US community practice settings. Figure 1 Figure 1. Rahman: Amgen Inc.: Current Employment, Current holder of stock options in a privately-held company. Kim: Amgen: Current Employment, Current equity holder in publicly-traded company. Mateus: Amgen Inc.: Current Employment, Other: Work at Amgen as a contract employee through DOCS. Keegan: Amgen Inc.: Current Employment, Current holder of stock options in a privately-held company.
Routledge eBooks, Dec 23, 2008
Routledge studies in development economics, Dec 23, 2008
Recently by using contamination families, a new way of modeling dependence has been introduced. I... more Recently by using contamination families, a new way of modeling dependence has been introduced. In this method, a sequence of parametric copulas is considered and in a few numbers of steps, accurate approximations for copula densities are obtained. By using the selection model method, the model complexity and number of model parameters are balanced. In this paper, two main variables in Iranian Household Income and Expenditure survey are considered and a copula density for those variables is estimated by using contamination family and selection model method.
Infection is a multistep process including adhesion, colonisation, invasion and multiplication wh... more Infection is a multistep process including adhesion, colonisation, invasion and multiplication which finally results in disease. Bacterial surface components and virulence factors are essential for all these different steps and they are co-ordinately regulated during the different steps of pathogenesis and infection. Host factors like the mucosal barrier, complement, phagocytosis, humoral and cellular immune response result in either elimination of pathogen or, if they fail to protect the body, progress of the disease process. LPS is an indispensable surface component and important virulence factor of gram- negative bacteria. The antibody response against different LPS serotypes of M. catarrhalis was studied in hyperimmune rabbit sera and a predominant serotype specific antibody response was observed. On the other hand, in the human host, humoral immune response was mainly observed against the common inner core region of the LPS. Immunochemical characterization of LPS epitopes by monoclonal antibodies confirmed the presence of a Gal-alpha-(1-4)-Gal epitope in the LPS of M. catarrhalis which is in agreement with the chemical structure of M. catarrhalis LPS. The humoral immune response against major outer membrane proteins was also studied in paired sera from patients suffering from a respiratory tract infection caused by M. catarrhalis. Titre rise in specific IgG 1, IgG2 and IgG3 was observed in most of the patients. Optimal sensitivity was obtained by using the OMP as antigen and testing for a rise of IgG3 antibodies. A good correlation was observed between total immunoglobulin response and IgG3 response. PilC, a 110 kD pilus associated protein was studied for function and localization. PilC is expressed from the pilC locus and N. meningitidis FAM20 expresses two PilC proteins, PilC 1 and PilC2 encoded by pilC1 and pilC2. PilC 1 and pilC2 are highly homologous but not identical. PilC1 and PilC2 share 84.7% similarity and 74.5% identity. PilC1 or PilC2 or both are essential for pilus biogenesis since pilC1-, pilC2- mutants were nonpiliated. In N. meningitidis, expression of PilC1, but not PilC2, contributes to attachment to host cells. Immunogold electron microscopy of cryosections and whole piliated bacteria indicated that PilC is located in the outer membrane and at the base of the pili. Key words: Moraxella catarrhalis/antibody/ LPS/ Neisseria/pili/PilC ISBN- 91-628-2314-
Leukemia & Lymphoma, Nov 12, 2022
Routledge eBooks, Dec 23, 2008
Bangladesh Journal of Fisheries
To assess the growth, survival and intactness of mud crabanexperiment was conducted for a period ... more To assess the growth, survival and intactness of mud crabanexperiment was conducted for a period of 120 days from July to October 2021 in the farmers ponds of Betbunia village under Paikgacha upazilla at Khulna Districts, Bangladesh. The crab Juvenile was collected from adjacent Shibsha River and stocked in a pond of 0.01 ha area with the stocking density at 1 m2,2m2, 3 m2in T1,T2 and T3 treatments with 2 replications each. Fresh choppedtilapiafish was fed and the feed was adjusted periodically in accordance with the growth performance. Production and physico-chemical parameters were recorded and analyzed according to standard methodsduring the culture period. Among these parameters salinity has significant (p<0.05) role on survival of mud crab.After 120 days of rearing, obtained average final weight was 97.8±13.86g, 94.22±9.25gand 117.77±14.34g; with the estimated yield of 371.56 kg/ha, 433.12 kg/ha and 376.56 kg/ha, survival was 38%, 46% and 32% in T1, T2 and T3 treatments resp...
The main concern of this paper is to examine the food availability, self-sufficiency rate and foo... more The main concern of this paper is to examine the food availability, self-sufficiency rate and food gap situation in Bangladesh. Attempt has been made to estimate food gaps between production and requirement for the last thirteen years. Future productions of rice and wheat have been forecasted by using appropriate econometric methods such as ARIMA and Holt's linear smoothing parameter approach. Forecasting of future food grain availability, food grain requirement and food gaps between production and requirement from 2010/11 to 2015/16 has been made. Finally some recommendations which would be helpful for improving the food security situation in Bangladesh have been suggested.
Segmentation on Computed Tomography (CT) image of heart and brain can be optimally posed as Bayes... more Segmentation on Computed Tomography (CT) image of heart and brain can be optimally posed as Bayesian labeling in which the segment of a image is defined as the maximum a posteriori (MAP) probability estimate of the true labeling. The Simulated Annealing (SA) algorithm is used to minimize the energy function associated with MRF posterior distribution function. The goal of this thesis paper is to minimize the energy function using Gaussian distribution and get accurate segmentation by slowly minimize the energy and simultaneously reduce the pixels which have no impact on the image at rapid rate to get the segmentation quickly without degrade the image. The propose algorithm able to get more precise segmentation.
Routledge Studies in Development Economics, 2008
Government gave compensation for such deaths. The death of sheep and goats are mainly due to 'Blu... more Government gave compensation for such deaths. The death of sheep and goats are mainly due to 'Blue Tongue' disease, apart from other diseases. Earter, under Janmabhoomi programme, the cattle-growers were given free medicines twice in a year and there used to be regular medical camps. But, now the Government of A.P. abolished Janmabhoomi programme ...(Interruptions)...And, this is the result of abolition of Janmabhoomi...(Interruptions)..There is also no vaccine to prevent 'Blue tongue' disease. Only now, research started at the National and State level to discover vaccine for this disease. In view of this, I request the Department of Animal Husbandry and the Union Health Ministry to help by way of conducting medical camps.. .(Interruptions)... providing medicines for cattle-growers in A.P. and also advice cattle-growers in A.P. to take precautions when such diseases occur and also request to consider sympathetically for giving compensation to them. Thank you. AN HON. MEMBER: Sir, the point is ...(Interruptions)...We have not abolished the programme...(Interruptions)... SHRIMATI N.P. DURGA: That is what I am saying ...(Interruptions)... Your Government has abolished the Janmabhoomi programme ...(Interruptions)... There are no regular medical camps. MR. CHAIRMAN: Hon. Members, the Constitution (One Hundred and Fourth Amendment) Bill, 2005, as passed by Lok Sabha, is being taken up in the House for consideration and passing. The Bill has to be passed by 2/3rd majority as required under Article 368 of the Constitution. To enable Members to be present at the time of division on various stages of the Bill, the first division on the Bill will be called at 4.30 p.m. If the House agrees, we may dispense with the lunch hour for today. SOME HON. MEMBERS: Agreed. MR. CHAIRMAN: Now, let us take up the Constitution (Amendment) Bill. Mr. Arjun Singh.
International Journal of Computer Applications, 2016
帝京経済学研究 the Teikyo University Economic Review, Mar 1, 2012