Nages Nagaratnam - Academia.edu (original) (raw)
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Papers by Nages Nagaratnam
Geriatric Diseases, 2018
TIA frequency increases with age reaching 10.2% in males and 7.4% in females and decreased in sub... more TIA frequency increases with age reaching 10.2% in males and 7.4% in females and decreased in subjects of both sexes aged 85 years or over. The symptoms of TIA vary widely depending on the area of the brain involved. Medical history of specific symptoms and thorough neurological and cardiovascular examinations provide the most important information to diagnose a TIA. TIA poses considerable difficulty in diagnosis, and diagnostic uncertainty is common. Patients presenting with TIA or minor stroke are at high risk of early stroke up to 10% in the first 48 h. Current international guidelines have adopted the ABCD2 score in risk stratification of patients with TIA. For a new-onset TIA patient, an ABCD2 can be a guide in the management.
Geriatric Diseases, 2018
Late-life anxiety disorders have been underestimated for several reasons, for example, older pers... more Late-life anxiety disorders have been underestimated for several reasons, for example, older persons tend to emphasise their physical complaints and less likely to report psychiatric symptoms. Panic attacks that begin in late life necessitate a search for a depressive disorder, physical illness or drugs that contribute to their presence. Of the anxiety disorders, phobia and general anxiety disorder (GAD) are the two most common in older people. This review summarises the main group of anxiety disorders and their management.
Aphasiology, 1998
Mixed transcortical aphasia is an uncommon occurrence with acute stroke. A 62 year old female is ... more Mixed transcortical aphasia is an uncommon occurrence with acute stroke. A 62 year old female is described with mixed transcortical aphasia and right hemiparesis and occlusion of the left internal carotid artery. The CT scan of the brain showed an infarction in the left putamen indicating that there is more than one anatomic possibility underlying mixed transcortical aphasia. Infarction of
Nature Reviews Neurology, 2013
People over the age of 90 years-the oldest old-are the fastest growing sector of the population. ... more People over the age of 90 years-the oldest old-are the fastest growing sector of the population. A substantial proportion of these individuals are affected by dementia, with major implications for the individual as well as society. Research on dementia in the oldest old is important for service planning, and the absence of dementia at this exceptional old age may serve as a model of successful ageing. This Review summarizes population-based epidemiological studies of dementia and its underlying neuropathology in nonagenarians and centenarians. The available data, although somewhat limited, show an age-specific and sex-specific profile of dementia status in very late life, resulting from a variety of neuropathologies that often co-occur. Extensive overlap in neuropathology between cognitively normal and cognitively impaired individuals is evident despite challenges to gathering data particular to this population. A complex picture is emerging of multiple pathogenetic mechanisms underlying dementia, and of the potential risk and protective factors for dementia that interact with genetics and lifestyle in normal and exceptional cognitive ageing.
Hemoglobin, 1989
... Med. J., i:866, 1958. Blackwell, RQ, de Silva, PE, de Silva, WAS, Nagaratnam, N., Warnasuriya... more ... Med. J., i:866, 1958. Blackwell, RQ, de Silva, PE, de Silva, WAS, Nagaratnam, N., Warnasuriya, N. Abeyaratne, DD, Ogren, ND, and Weng, M. I., Trop. Geogr. Med., 26:214, 1974. ... Clin., 38:154, 1969. Astaldi, G., Tolentino, P., and Saccheti, C., Helv. Paediatr. Acta, 6:50, 1951. ...
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Australian and New Zealand journal of medicine, 1991
Neurorehabilitation and Neural Repair, 1990
Neurorehabilitation and Neural Repair, 2001
Critical illness neuropathy frequently accompanies the septic syndrome in intensive care units. A... more Critical illness neuropathy frequently accompanies the septic syndrome in intensive care units. Another entity that may occur independently or concurrently in critically ill patients is a myopathy, giving rise to difficulties in distinguishing between them. The two patients described had sensorimotor axonal peripheral neuropathy. Axonopathy as a rule has a poor prognosis for recovery, which is slow and often incomplete. There are few reports of the functional outcome after rehabilitation therapy. The two patients described had 5-6 weeks of active rehabilitation therapy with improvement from moderate/severe disability at the onset to slight debility at the end of therapy.
Geriatric Diseases, 2018
TIA frequency increases with age reaching 10.2% in males and 7.4% in females and decreased in sub... more TIA frequency increases with age reaching 10.2% in males and 7.4% in females and decreased in subjects of both sexes aged 85 years or over. The symptoms of TIA vary widely depending on the area of the brain involved. Medical history of specific symptoms and thorough neurological and cardiovascular examinations provide the most important information to diagnose a TIA. TIA poses considerable difficulty in diagnosis, and diagnostic uncertainty is common. Patients presenting with TIA or minor stroke are at high risk of early stroke up to 10% in the first 48 h. Current international guidelines have adopted the ABCD2 score in risk stratification of patients with TIA. For a new-onset TIA patient, an ABCD2 can be a guide in the management.
Geriatric Diseases, 2018
Late-life anxiety disorders have been underestimated for several reasons, for example, older pers... more Late-life anxiety disorders have been underestimated for several reasons, for example, older persons tend to emphasise their physical complaints and less likely to report psychiatric symptoms. Panic attacks that begin in late life necessitate a search for a depressive disorder, physical illness or drugs that contribute to their presence. Of the anxiety disorders, phobia and general anxiety disorder (GAD) are the two most common in older people. This review summarises the main group of anxiety disorders and their management.
Aphasiology, 1998
Mixed transcortical aphasia is an uncommon occurrence with acute stroke. A 62 year old female is ... more Mixed transcortical aphasia is an uncommon occurrence with acute stroke. A 62 year old female is described with mixed transcortical aphasia and right hemiparesis and occlusion of the left internal carotid artery. The CT scan of the brain showed an infarction in the left putamen indicating that there is more than one anatomic possibility underlying mixed transcortical aphasia. Infarction of
Nature Reviews Neurology, 2013
People over the age of 90 years-the oldest old-are the fastest growing sector of the population. ... more People over the age of 90 years-the oldest old-are the fastest growing sector of the population. A substantial proportion of these individuals are affected by dementia, with major implications for the individual as well as society. Research on dementia in the oldest old is important for service planning, and the absence of dementia at this exceptional old age may serve as a model of successful ageing. This Review summarizes population-based epidemiological studies of dementia and its underlying neuropathology in nonagenarians and centenarians. The available data, although somewhat limited, show an age-specific and sex-specific profile of dementia status in very late life, resulting from a variety of neuropathologies that often co-occur. Extensive overlap in neuropathology between cognitively normal and cognitively impaired individuals is evident despite challenges to gathering data particular to this population. A complex picture is emerging of multiple pathogenetic mechanisms underlying dementia, and of the potential risk and protective factors for dementia that interact with genetics and lifestyle in normal and exceptional cognitive ageing.
Hemoglobin, 1989
... Med. J., i:866, 1958. Blackwell, RQ, de Silva, PE, de Silva, WAS, Nagaratnam, N., Warnasuriya... more ... Med. J., i:866, 1958. Blackwell, RQ, de Silva, PE, de Silva, WAS, Nagaratnam, N., Warnasuriya, N. Abeyaratne, DD, Ogren, ND, and Weng, M. I., Trop. Geogr. Med., 26:214, 1974. ... Clin., 38:154, 1969. Astaldi, G., Tolentino, P., and Saccheti, C., Helv. Paediatr. Acta, 6:50, 1951. ...
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Diseases in the Elderly, 2016
Australian and New Zealand journal of medicine, 1991
Neurorehabilitation and Neural Repair, 1990
Neurorehabilitation and Neural Repair, 2001
Critical illness neuropathy frequently accompanies the septic syndrome in intensive care units. A... more Critical illness neuropathy frequently accompanies the septic syndrome in intensive care units. Another entity that may occur independently or concurrently in critically ill patients is a myopathy, giving rise to difficulties in distinguishing between them. The two patients described had sensorimotor axonal peripheral neuropathy. Axonopathy as a rule has a poor prognosis for recovery, which is slow and often incomplete. There are few reports of the functional outcome after rehabilitation therapy. The two patients described had 5-6 weeks of active rehabilitation therapy with improvement from moderate/severe disability at the onset to slight debility at the end of therapy.