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Papers by Nicolas Gillain
Patient Education and Counseling, 2019
Objectives Several concepts on collaboration between patients and healthcare systems have emerged... more Objectives Several concepts on collaboration between patients and healthcare systems have emerged in the literature but there is little consensus on their meanings and differences. In this study, "patient participation" and related concepts were studied by focusing on the dimensions that compose them. This review follows two objectives: (1) to produce a detailed and comprehensive overview of the "patient participation" dimensions; (2) to identify differences and similarities between the related concepts. Methods A scoping review was performed to synthesize knowledge into a conceptual framework. An electronic protocol driven search was conducted in two bibliographic databases and a thematic analysis was used to analyse the data. Results The search process returned 39 articles after exclusion for full data extraction and analysis. Through the thematic analysis, the dimensions, influencing factors and expected outcomes of "patient participation" were determined. Finally, differences between the included concepts were identified. Conclusion This global vision of "patient participation" allows us to go beyond the distinctions between the existing concepts and reveals their common goal to include the patient in the healthcare system. Practice implications This scoping review provides useful information to propose a conceptual model of "patient participation", which could impact clinical practice and medical training programs.
Human Reproduction, 2013
study question: What is the effect of a legal limitation of the number of embryos that can be tra... more study question: What is the effect of a legal limitation of the number of embryos that can be transferred in an assisted reproductive technology (ART) cycle on the multiple delivery rate? summary answer: The Belgian national register shows that the introduction of reimbursement of ART laboratory costs in July 2003, and the imposition of a legal limitation of the number of embryos transferred in the same year, were associated with a .50% reduction of the multiple pregnancy rate from 27 to 11% between 2003 and the last assessment in 2010, without any reduction of the pregnancy rate per cycle. what is known already: Individual Belgian IVF centres have published their results since the implementation of the law, and these show a decrease in the multiple pregnancy rate on a centre by centre basis. However, the overall national picture remains unpublished.
Human Reproduction, 2015
How do the national cumulative (multiple) live birth rates over complete assisted reproduction te... more How do the national cumulative (multiple) live birth rates over complete assisted reproduction technology (ART) courses of treatment per woman in Belgium compare to those in other registries? summary answer: Cumulative live birth rates (CLBRs) remain high with a low cumulative multiple live birth rate when compared with other registries and publications. what is known already: In ART, a reduction in the multiple live birth rate could be achieved by reducing the number of embryos transferred. It has been shown that by doing so, live birth rates per cycle were maintained, particularly when the augmentation effect of attached frozen-thawed cycles was considered. study design, size, duration: A retrospective cohort study included all patients with a Belgian national insurance number who were registered in the national ART registry (Belrap) and who started a first fresh ART cycle between 1 July 2009 until 31 December 2011 with follow up until 31 December 2012. We analysed 12 869 patients and 38 008 cycles (both fresh and attached frozen cycles). participants, materials, settings, methods: CLBRs per patient who started a first ART cycle including fresh and consecutive frozen cycles leading to a live birth. Conservative estimates of cumulative live birth assumed that patients who did not return for treatment had no chance of achieving an ART-related live birth, whereas optimal estimates assumed that women discontinuing treatment would have the same chance of achieving a live birth as those continuing treatment. A maximum of six fresh ART cycles with corresponding frozen cycles was investigated and compared with other registries and publications. main results and role of chance: The CLBR was age dependent and declined from 62.9% for women ,35 years, to 51.4% for women 35-37 years, to 34.1% for women 38-40 years and 17.7% for women 41-42 years in the conservative analysis after six cycles. In the optimal estimate, the CLBR declined from 85.9% for women ,35 years, to 72.0% for women 35-37 years, to 50.4% for women 38-40 years and 36.4% for women 41-42 years. The cumulative multiple live birth rates for the whole population were 5.1 and 8.6% for the conservative and optimal estimate, respectively. limitations, reasons for caution: Conservative and optimal estimates use assumptions for the whole ART population and do not take the individual patient into account.
BMJ Open, 2022
Introduction For a safe and sustainable return to normal functioning of academic activities in hi... more Introduction For a safe and sustainable return to normal functioning of academic activities in higher education, objective-driven testing strategies that are flexible and rapidly adaptable are essential to effectively monitor and respond to new developments of the COVID-19 pandemic. To date, prospective longitudinal research on SARS-CoV-2 antibody testing in saliva and seroprevalence in higher education contexts is substantially lacking, limiting our understanding of COVID-19 prevalence, incidence and nature of the immune response to SARS-CoV-2 at various stages of the infection and vaccination. To address this lack of evidence, a prospective population-based cohort study (SARSSURV-ULiège) has recently been started. Methods and analysis Students (n=1396) and staff members (n=1143) of the University of Liège are followed up over more than 1 year. All participants are required to complete anamnestic, clinical and vaccine hesitancy questionnaires for medical histories and undertaken tr...
Revue médicale de Liège, 2018
5. Systematic record of events: promote it and spread uniform tools to improve it. International ... more 5. Systematic record of events: promote it and spread uniform tools to improve it. International guidelines are partially implemented in Belgium. A small proportion of settings (3-34%) fully apply the basic audit criteria promoted in the NHS-NICE guidelines. A majority of settings (47-74%) finds these recommendations as fully feasible. Main difficulties were identified: lack of time, patient's illness, professional's shortage, scientific tools unknown, lack of institutional policy, inappropriate recommendation. Recommendations to healthcare institutions and authorities were proposed but their actual implementation will face difficulties and require further investigations. Level of compliance No Partial Full 1. Systematic risk assessment 21% 76% 3% 2. Training policy 0% 66% 34% 3. Patient information 1% 88% 11% 4. Patient-centered management 1% 84% 14% 5. Systematic record of events: Rapid tranquilization 59% 29% 12% Isolation 7% 63% 30% Physical intervention 53% 32% 15% Feas...
Patient Education and Counseling, 2019
Objectives Several concepts on collaboration between patients and healthcare systems have emerged... more Objectives Several concepts on collaboration between patients and healthcare systems have emerged in the literature but there is little consensus on their meanings and differences. In this study, "patient participation" and related concepts were studied by focusing on the dimensions that compose them. This review follows two objectives: (1) to produce a detailed and comprehensive overview of the "patient participation" dimensions; (2) to identify differences and similarities between the related concepts. Methods A scoping review was performed to synthesize knowledge into a conceptual framework. An electronic protocol driven search was conducted in two bibliographic databases and a thematic analysis was used to analyse the data. Results The search process returned 39 articles after exclusion for full data extraction and analysis. Through the thematic analysis, the dimensions, influencing factors and expected outcomes of "patient participation" were determined. Finally, differences between the included concepts were identified. Conclusion This global vision of "patient participation" allows us to go beyond the distinctions between the existing concepts and reveals their common goal to include the patient in the healthcare system. Practice implications This scoping review provides useful information to propose a conceptual model of "patient participation", which could impact clinical practice and medical training programs.
Human Reproduction, 2013
study question: What is the effect of a legal limitation of the number of embryos that can be tra... more study question: What is the effect of a legal limitation of the number of embryos that can be transferred in an assisted reproductive technology (ART) cycle on the multiple delivery rate? summary answer: The Belgian national register shows that the introduction of reimbursement of ART laboratory costs in July 2003, and the imposition of a legal limitation of the number of embryos transferred in the same year, were associated with a .50% reduction of the multiple pregnancy rate from 27 to 11% between 2003 and the last assessment in 2010, without any reduction of the pregnancy rate per cycle. what is known already: Individual Belgian IVF centres have published their results since the implementation of the law, and these show a decrease in the multiple pregnancy rate on a centre by centre basis. However, the overall national picture remains unpublished.
Human Reproduction, 2015
How do the national cumulative (multiple) live birth rates over complete assisted reproduction te... more How do the national cumulative (multiple) live birth rates over complete assisted reproduction technology (ART) courses of treatment per woman in Belgium compare to those in other registries? summary answer: Cumulative live birth rates (CLBRs) remain high with a low cumulative multiple live birth rate when compared with other registries and publications. what is known already: In ART, a reduction in the multiple live birth rate could be achieved by reducing the number of embryos transferred. It has been shown that by doing so, live birth rates per cycle were maintained, particularly when the augmentation effect of attached frozen-thawed cycles was considered. study design, size, duration: A retrospective cohort study included all patients with a Belgian national insurance number who were registered in the national ART registry (Belrap) and who started a first fresh ART cycle between 1 July 2009 until 31 December 2011 with follow up until 31 December 2012. We analysed 12 869 patients and 38 008 cycles (both fresh and attached frozen cycles). participants, materials, settings, methods: CLBRs per patient who started a first ART cycle including fresh and consecutive frozen cycles leading to a live birth. Conservative estimates of cumulative live birth assumed that patients who did not return for treatment had no chance of achieving an ART-related live birth, whereas optimal estimates assumed that women discontinuing treatment would have the same chance of achieving a live birth as those continuing treatment. A maximum of six fresh ART cycles with corresponding frozen cycles was investigated and compared with other registries and publications. main results and role of chance: The CLBR was age dependent and declined from 62.9% for women ,35 years, to 51.4% for women 35-37 years, to 34.1% for women 38-40 years and 17.7% for women 41-42 years in the conservative analysis after six cycles. In the optimal estimate, the CLBR declined from 85.9% for women ,35 years, to 72.0% for women 35-37 years, to 50.4% for women 38-40 years and 36.4% for women 41-42 years. The cumulative multiple live birth rates for the whole population were 5.1 and 8.6% for the conservative and optimal estimate, respectively. limitations, reasons for caution: Conservative and optimal estimates use assumptions for the whole ART population and do not take the individual patient into account.
BMJ Open, 2022
Introduction For a safe and sustainable return to normal functioning of academic activities in hi... more Introduction For a safe and sustainable return to normal functioning of academic activities in higher education, objective-driven testing strategies that are flexible and rapidly adaptable are essential to effectively monitor and respond to new developments of the COVID-19 pandemic. To date, prospective longitudinal research on SARS-CoV-2 antibody testing in saliva and seroprevalence in higher education contexts is substantially lacking, limiting our understanding of COVID-19 prevalence, incidence and nature of the immune response to SARS-CoV-2 at various stages of the infection and vaccination. To address this lack of evidence, a prospective population-based cohort study (SARSSURV-ULiège) has recently been started. Methods and analysis Students (n=1396) and staff members (n=1143) of the University of Liège are followed up over more than 1 year. All participants are required to complete anamnestic, clinical and vaccine hesitancy questionnaires for medical histories and undertaken tr...
Revue médicale de Liège, 2018
5. Systematic record of events: promote it and spread uniform tools to improve it. International ... more 5. Systematic record of events: promote it and spread uniform tools to improve it. International guidelines are partially implemented in Belgium. A small proportion of settings (3-34%) fully apply the basic audit criteria promoted in the NHS-NICE guidelines. A majority of settings (47-74%) finds these recommendations as fully feasible. Main difficulties were identified: lack of time, patient's illness, professional's shortage, scientific tools unknown, lack of institutional policy, inappropriate recommendation. Recommendations to healthcare institutions and authorities were proposed but their actual implementation will face difficulties and require further investigations. Level of compliance No Partial Full 1. Systematic risk assessment 21% 76% 3% 2. Training policy 0% 66% 34% 3. Patient information 1% 88% 11% 4. Patient-centered management 1% 84% 14% 5. Systematic record of events: Rapid tranquilization 59% 29% 12% Isolation 7% 63% 30% Physical intervention 53% 32% 15% Feas...