PAVEL KEWIN DELGADO SARMIENTO - Academia.edu (original) (raw)
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Russian Academy of Sciences, Saint Petersburg Branch of the Institute for the History of Science and Technology
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Papers by PAVEL KEWIN DELGADO SARMIENTO
Федеральное государственное бюджетное образовательное учреждение высшего образования «Санкт-Петербургский государственный университет», 2018
Revista De La Sociedad Quimica Del Peru, 2013
Revista De La Sociedad Quimica Del Peru, 2013
Journal of Chemistry
The venom of snakes is composed of a heterogeneous mixture of simple and complex substances, with... more The venom of snakes is composed of a heterogeneous mixture of simple and complex substances, with inflammation and hyperalgesia being the first symptom caused by the action of Bothrops venom, generating processes such as leukocyte infiltration, hemorrhage, and the intravascular formation of thrombi. Within the simple substances, we have free amino acids, peptides, nucleotides, carbohydrates, lipids, and biogenic amines (organic molecules) as well as cations and anions (inorganic constituents). Of the ions, we can highlight calcium, which is an important cofactor of some proteolytic enzymes as well as phospholipases A2. And magnesium and zinc are important cofactors of venom metalloproteases. Complex substances are related to proteins and enzymes. Studies related to the total venom of snake present in several organic substances act as pain mediators and are called biogenic amines, such as bradykinin, histamine, 4-hydroxytryptamine, N-methyl-5-hydroxytryptamine, N′-N′-dimethyl-5-hydro...
Федеральное государственное бюджетное образовательное учреждение высшего образования «Санкт-Петербургский государственный университет», 2018
Revista De La Sociedad Quimica Del Peru, 2013
Revista De La Sociedad Quimica Del Peru, 2013
Journal of Chemistry
The venom of snakes is composed of a heterogeneous mixture of simple and complex substances, with... more The venom of snakes is composed of a heterogeneous mixture of simple and complex substances, with inflammation and hyperalgesia being the first symptom caused by the action of Bothrops venom, generating processes such as leukocyte infiltration, hemorrhage, and the intravascular formation of thrombi. Within the simple substances, we have free amino acids, peptides, nucleotides, carbohydrates, lipids, and biogenic amines (organic molecules) as well as cations and anions (inorganic constituents). Of the ions, we can highlight calcium, which is an important cofactor of some proteolytic enzymes as well as phospholipases A2. And magnesium and zinc are important cofactors of venom metalloproteases. Complex substances are related to proteins and enzymes. Studies related to the total venom of snake present in several organic substances act as pain mediators and are called biogenic amines, such as bradykinin, histamine, 4-hydroxytryptamine, N-methyl-5-hydroxytryptamine, N′-N′-dimethyl-5-hydro...