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Papers by MARLUS PEDROSA

Revista da Faculdade de Odontologia - UPF, 2017

Cimentos biocerâmicos vêem se tornando populares na ndodontia como material obturador do sistema ... more Cimentos biocerâmicos vêem se tornando populares na ndodontia como material obturador do sistema de canais radicular devido às suas várias vantagens. Objetivo: Revisar a literatura atualmente disponível sobre as propriedades de cimentos biocerâmicos na endodontia. Metodologia: Uma pesquisa bibliográfica exploratória foi realizada utilizando as bases de dados eletrônicas Public Medline (PubMed), Scopus, Embase, e Web of Science empregando o termo de busca “Bioceramic” AND “Endodontic”. Os critérios de inclusão foram: artigos de pesquisas originais e ensaios clínicos publicados em português, espanhol e inglês. Não foram aplicados limites a data de publicação. Resultados: Foram identificados 30 estudos que abordaram propriedades de cimentos biocerâmicos em endodontia publicados em um período de 7 anos (2011-2017). As propriedades e características vantajosas destacadas nos estudos foram: biocompatibilidade, citotoxicidade, bioatividade, capacidade de manchamento dentário, radiopacidade...

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2022

Objective: To compare the cytotoxicity of commercial reparative endodontic cements on human perio... more Objective: To compare the cytotoxicity of commercial reparative endodontic cements on human periodontal ligament stem cells (hPDLSCs). Material and Methods: The culture of hPDLSCs was established. Cell density was set at 2 × 10 4 cells/well in 96-well plates. Extracts of Biodentine, Bio-C Repair, Cimmo HD, MTA Repair HP and White MTA were prepared. Then, the extracts were diluted (pure, 1:4 and 1:16) and inserted into cell-seeded wells for 24, 48, and 72 h to assess cell viability through MTT assay. hPDLSCs incubated with culture medium alone served as a negative control group. Data were analyzed by Two-Way ANOVA and Tukey's test (α=0.05). Results: At 24 h, pure extract of MTA Repair HP and Biodentine 1:16 presented higher cell viability compared to control. Lower cell viability was found for pure extract of Cimmo HD, MTA Repair HP 1:4 and 1:16, and White MTA 1:16. At 48 h, pure extract of Bio-C Repair and MTA Repair HP presented higher cell viability compared to control. At 72 h, only the pure extract of MTA Repair HP led to higher cell proliferation compared to control. Conclusion: Biodentine, Bio-C Repair and MTA Repair HP were able to induce hPDLSCs proliferation. Cimmo HD and White MTA were found to be mostly cytotoxic in hPDLSCs.

Odontología Sanmarquina, 2022

Los profesionales de la salud oral tienen un mayor riesgo de infección con el nuevo coronavirus 2... more Los profesionales de la salud oral tienen un mayor riesgo de infección con el nuevo coronavirus 2019 (COVID-19), debido a la comunicación cercana a la cavidad oral y la exposición a saliva, sangre y otros fluidos corporales. Los enfoques digitales pueden reducir el tiempo clínico y contribuir a limitar el riesgo de infección. El objetivo del presente trabajo es presentar un enfoque digital para restaurar un diente anterior traumatizado, durante la pandemia de COVID-19. Paciente sexo feminino de 28 años, con movilidad anormal de la pieza 1.1 y antecedente de traumatismo dental en la adolescencia. Se realizó una evaluación inicial para detectar signos y síntomas de una posible infección por COVID-19. Las imágenes de la tomografía computarizada mostraron fractura coronaria y presencia de reabsorción cervical externa en el incisivo central derecho. El plan de tratamiento consistió en la rehabilitación del diente fracturado a través de una restauración retenida con un poste de fibra de v...

Composite resin restoration on posterior teeth through the incremental technique is, generally, a... more Composite resin restoration on posterior teeth through the incremental technique is, generally, a time consuming procedure with risk of contamination between the layers. Therefore, It has been developed techniques to facilitate the work of dental professionals and achieve aesthetic and functional results such as the occlusal stamp technique. This technique makes the procedure faster by accurately copying the occlusal anatomy, allowing a little or no occlusal adjustment. The aim of the present study was to present a clinical case in which the stamp technique was performed and to describe the restorative treatment in a patient with hidden carie. It was observed that the stamp technique, when performed correctly, is a reliable and predictable method for the reconstruction of the occlusal anatomy.

Introducao: as cirurgias em terceiros molares retidos sao procedimentos frequentes na pratica cli... more Introducao: as cirurgias em terceiros molares retidos sao procedimentos frequentes na pratica clinica de cirurgioes-dentistas e estao associadas com inumeras complicacoes trans e pos-operatorias. Alguns autores recomendam a utilizacao de antibioticos locais e sistemicos com o intuito de prevenir essas complicacoes. Nao obstante, a profilaxia antibiotica para extracao de terceiros molares e objeto de controversias no tocante a sua eficacia com relacao a prevencao de complicacoes pos-cirurgicas onde evidencias cientificas acerca de suas vantagens e desvantagens ainda sao limitadas. Objetivo: o presente trabalho objetivou buscar na literatura vigente evidencias cientificas acerca do papel da profilaxia antibiotica para prevencao ou reducao de complicacoes infecciosas pos-operatorias no contexto das cirurgias em terceiros molares retidos em pacientes saudaveis. Metodo: para tal, realizou-se uma pesquisa bibliografica de carater exploratorio bases de dados eletronicas SciELO, PubMed, EBS...

O objetivo deste estudo foi identificar os conceitos sobre saude dos estudantes de odontologia de... more O objetivo deste estudo foi identificar os conceitos sobre saude dos estudantes de odontologia de instituicao de ensino superior bem como avaliar sob quais conceitos os estudantes estao se pautando no enfrentamento dos problemas de saude. Trata-se de um estudo descritivo de corte transversal aprovado pelo Comite de Etica em Pesquisa NOVAFAPI (Parecer 0355.0.043.000-11). A amostra da pesquisa foi composta de 200 alunos (93,46 %), sendo a maioria do genero feminino (53%), e o conceito de saude mais frequente foi de bem-estar (51,6 %) em seus diferentes aspectos. Analisando o cruzamento de tabelas, genero e abordagem dos temas sociais, houve diferenca estatisticamente significativa (p=0,042), sendo comprovado pelo teste exato de Fischer (p=0,029). A maioria dos estudantes tem saude como bem-estar, fato este relacionado a difusao do conceito da OMS.

Brazilian Dental Journal, 2021

This study investigated the effect of three commercial calcium silicate-based materials (CSBM) on... more This study investigated the effect of three commercial calcium silicate-based materials (CSBM) on cytotoxicity and pro-and anti-inflammatory cytokines production in cultured human periodontal ligament stem cells (hPDLSCs). Culture of hPDLSCs was established and characterized. Extracts of Bio-C Sealer (Angelus, Londrina, PR, Brazil), MTA Fillapex (Angelus, Londrina, PR, Brazil) and PBS Cimmo HP (Cimmo Soluções em Saúde, Pouso Alegre, MG, Brazil) were prepared by placing cement specimens (5 x 3 mm) in culture medium. Then, the extracts were serially two-fold diluted (1, 1:2, 1:4, 1:8, 1:16) and inserted into the cell-seeded wells for 24, 48 and 72 h for MTT assays. TNF-α and IL-10 cytokines were quantified by ELISA at 24h-cell supernatants. Data were analyzed by ANOVA and Tukey’s test (α = 0.05). All CSBM exhibited some cytotoxicity that varied according to extract concentration and time of evaluation. MTA Fillapex presented the highest cytotoxic effects with significant reduction of ...

Brazilian Dental Science, 2021

Introduction: Ceramic veneers represent a treatment approach in aesthetic dentistry. They are ind... more Introduction: Ceramic veneers represent a treatment approach in aesthetic dentistry. They are indicated in cases of alterations in size, contour, form and color of the teeth. The clinical and radiographic examinations may not allow the correct identification of failures in the treatment with ceramic veneers. Objective: To report the use of Optical Coherence Tomography (OCT) for the evaluation and repair of an aesthetic oral rehabilitation involving ceramic veneers. Case report: A 24-year-old female patient complained of unsatisfied color change in the ceramic veneer placed on the right maxillary central incisor. The clinical examination showed color changes between the middle and incisal thirds of mesial surface of the tooth crown. The OCT sagittal images evidenced the presence of bubbles or gaps in the adhesive interface. The treatment consisted of repair of the restoration by infiltration of a composite resin. Conclusion: The OCT was found to be valid tool to evaluate the adaptati...

RGO - Revista Gaúcha de Odontologia, 2020

Since the outbreak of the Coronavirus Disease 2019 (COVID-19), caused by the Severe Acute Respira... more Since the outbreak of the Coronavirus Disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), numerous restrictive measures have been adopted by governments of different countries. The return to elective dental care in Brazil is a reality even during the COVID-19 pandemic. During restorative dental procedures, the dental professional requires close contact with the patient, being exposed to contaminated saliva and fluids. In addition, transmission of COVID-19 by the generation of aerosol produced by dental handipieces may be possible. Thus, the dental staff must know how to act during restorative dental procedures, putting into practice the correct clinical protocols to avoid cross-contamination and COVID-19 spread. The purpose of this article is to review the literature on the biosafety practices especially in the context of restorative dental procedures in times of COVID-19.

Journal of Diabetes Science and Technology, 2020

Patients with diabetes are at increased risk of the severe course of the coronavirus disease 2019... more Patients with diabetes are at increased risk of the severe course of the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We read with great interest the article of Pfützner et al. 1 in the Journal of Diabetes Science and Technology (JDST). The authors pointed out the relationship between periodontal diseases, diabetes, and increased COVID-19 mortality. Along with the possibility of salivary gland infection, some reports on the literature have also shown hyposalivation and taste alterations in COVID-19 patients. In this letter, we would like to call the attention of the possible long-term oral consequences that individuals affected by COVID-19 may present, especially regarding diabetes. The SARS-CoV and the SARS-CoV-2 share similarities. Both viruses use angiotensin-converting enzyme 2 (ACE-2) as receptor for entry into target cells and transmembrane serine protease 2 for priming. 2 ACE-2 is expressed in several tissues, including salivary glands and pancreas. In the pancreas, the previous SARS-CoV was found to damage islets, reduce insulin release, and cause acute insulin-dependent diabetes mellitus. 3 It was reported that, after hospitalization, more than 50% of the patients with SARS-CoV infection became diabetic. 3 Interestingly, the SARS-CoV-2 infection was shown to cause ketosis or ketoacidosis and induced diabetic ketoacidosis for those with diabetes. 4 The SARS-CoV-2 could also infect and cause damage to α-cells and β-cells of the pancreas, aggravating its function. 5,6 Thus, it is possible that COVID-19 trigger diabetes in some individuals. Literature reports that patients with diabetes often present oral repercussions, including periodontal diseases and salivary gland dysfunction, among others. It is well known that oxidative stress plays an important role in diabetes. Oxidative stress has also been suggested as a link between diabetes and periodontal disease. Interestingly, literature also suggested oxidative stress as a player in COVID-19 infection. According to our group experience, the salivary glands present oxidative damage and disturbances in the metabolism and antioxidant 948041D STXXX10.

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2020

The world is under the threat of the novel coronavirus disease 2019 (COVID-19) caused by the seve... more The world is under the threat of the novel coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite several efforts to contain the disease spread, it still constitutes a public health emergency of international concern. Several published reports in the scientific literature called attention of the oral cavity as the potential route of infection, the implications for dental practice and the use of saliva in the diagnose of the COVID-19. The aim of this article is to provide an overview of the literature on the salivary glands and saliva in the context of SARS-CoV-2 infection. A brief discussion of taste disturbances and oral findings in COVID-19 patients is also presented. The literature shows that SARS-CoV-2 could infect the salivary glands. It is not possible, however, to make speculations regarding them as reservoirs for the SARS-CoV-2. In addition, patients with COVID-19 presented several oral repercussions, including hyposalivation and taste disturbances. A few reports showed oral ulcers and blisters associated with SARS-CoV-2 infection. However, it remains not fully understood and might lead to erroneous assumptions. Overall, further studies are necessary to understand the real role of salivary glands and saliva in the context of SARS-CoV-2 infection.

Full Dentistry in Science, 2019

Descrever a harmonização do sorriso, através da cirurgia plástica gengival em uma condição descri... more Descrever a harmonização do sorriso, através da cirurgia plástica gengival em uma condição descrita como sorriso gengival. Detalhamento do caso: Paciente, sexo feminino, 21 anos de idade, apresentou-se na Clínica de Odontologia da FURB, insatisfeita com a estética vermelha de seu sorriso. Realizados os exames periodontais, e comprovado o status de saúde periodontal, indicou-se e a cirúrgica plástica periodontal. Modelos prévios, através de um medidor de proporcionalidade de Chu, permitiram uma correta avaliação do aumento da coroa clínica dos dentes necessário e mantendo uma proporção harmônica dos mesmos. Este ensaio, após testado na paciente através de um mockup, serviu para a montagem do planejamento cirúrgico para diminuição da estética vermelha. O controle fotográfico foi realizado antes do ato cirúrgico, no transcirúrgico, no pós operatório imediato, aos 7,14, 45, 60 e 90 dias após a realização da cirurgia. Os resultados permitiram obter um contorno gengival completamente estabelecido, arco côncavo gengival harmônico e ausência de discrepância nas curvaturas. Considerações finais: Concluiu-se que a realização da cirurgia plástica periodontal permitiu um resultado estético satisfatório com diminuição do sorriso gengival da paciente.

Brazilian Dental Science, 2018

Objective: The objective of this study was to evaluate the 6-month clinical performance of class ... more Objective: The objective of this study was to evaluate the 6-month clinical performance of class I occlusal composite resin restorations through a multicenter, randomized, double-blind, clinical trial. Material e Métodos: Two hundred and eighty class I occlusal restorations were performed in 70 patients (aged between 17 to 50 years). The restorations were divided into four groups: G1 (Filtek P60/3M ESPE); G2 (Rok/SDI); G3 (Filtek™ P90/3M ESPE); G4 (Evolux/Dentsply). Two pre-calibrated dental practitioners performed and evaluated the restorative procedures regarding to color match, marginal discoloration, recurrent caries, wear (anatomic form) and marginal integrity according to the USPHS criteria. Resultados: In 85.8% of the evaluated restorations was observed the ideal score (A) for color match; 91.4% for marginal discoloration; 100% for recurrent caries; 87.7% for wear (anatomic form) and 99.3% for marginal integrity. Conclusion: The composite resins used in this study presented ...

Revista da ABENO, 2018

O objetivo deste estudo foi avaliar o perfil de egressos do curso de graduação em Odontologia da ... more O objetivo deste estudo foi avaliar o perfil de egressos do curso de graduação em Odontologia da Universidade Federal de Pernambuco, formados no modelo curricular vigente até o ano de 2009, denominado 6404. Uma amostra de conveniência de 233 cirurgiões-dentistas graduados de 2003 a 2008 foi entrevistada individualmente com uso de formulário específico. Os dados obtidos foram tabulados e submetidos à análise estatística descritiva e inferencial (teste chi-quadrado Pearson ou teste Exato de Fisher) (α=5%). Verificou-se que 30,9% dos egressos atuavam somente como profissionais liberais, 15% apenas em cargo público e que 40,8% associavam o exercício liberal à docência, cargo público e/ou empresa privada. O grau de satisfação com a profissão mostrou-se diretamente relacionado à renda e não aos conhecimentos adquiridos. A renda foi influenciada pelo tipo de exercício profissional. Concluiu-se que os egressos possuem o perfil de um profissional preocupado com a educação continuada e que ge...

Brazilian Dental Science, 2018

Objective: To evaluate the oral health self-perception and the influence of dental treatment on t... more Objective: To evaluate the oral health self-perception and the influence of dental treatment on the multidisciplinary approach of adolescent victims of sexual abuse. Material and Methods: It was adopted a qualitative methodology that emphasized the deepening and comprehension of the answers obtained. Six adolescents, from both genders, victims of sexual abuse in the last two years, aged between 10 and 15, took part of the study. A questionnaire was applied before and after the dental treatment in order to evaluate changes in the self-perception and self-esteem of the individuals. The answers were categorized into two thematic axes with the use of the qualitative content analysis: self-perception and self-esteem. Psychological attendance prior and after the dental interventions enabled to comprehend the changes observed. Results: The participants presented a coherent self-perception in relation to the present clinical situation and an increase of their self-esteem after the dental in...

Revista da Faculdade de Odontologia - UPF, 2017

Cimentos biocerâmicos vêem se tornando populares na ndodontia como material obturador do sistema ... more Cimentos biocerâmicos vêem se tornando populares na ndodontia como material obturador do sistema de canais radicular devido às suas várias vantagens. Objetivo: Revisar a literatura atualmente disponível sobre as propriedades de cimentos biocerâmicos na endodontia. Metodologia: Uma pesquisa bibliográfica exploratória foi realizada utilizando as bases de dados eletrônicas Public Medline (PubMed), Scopus, Embase, e Web of Science empregando o termo de busca “Bioceramic” AND “Endodontic”. Os critérios de inclusão foram: artigos de pesquisas originais e ensaios clínicos publicados em português, espanhol e inglês. Não foram aplicados limites a data de publicação. Resultados: Foram identificados 30 estudos que abordaram propriedades de cimentos biocerâmicos em endodontia publicados em um período de 7 anos (2011-2017). As propriedades e características vantajosas destacadas nos estudos foram: biocompatibilidade, citotoxicidade, bioatividade, capacidade de manchamento dentário, radiopacidade...

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2022

Objective: To compare the cytotoxicity of commercial reparative endodontic cements on human perio... more Objective: To compare the cytotoxicity of commercial reparative endodontic cements on human periodontal ligament stem cells (hPDLSCs). Material and Methods: The culture of hPDLSCs was established. Cell density was set at 2 × 10 4 cells/well in 96-well plates. Extracts of Biodentine, Bio-C Repair, Cimmo HD, MTA Repair HP and White MTA were prepared. Then, the extracts were diluted (pure, 1:4 and 1:16) and inserted into cell-seeded wells for 24, 48, and 72 h to assess cell viability through MTT assay. hPDLSCs incubated with culture medium alone served as a negative control group. Data were analyzed by Two-Way ANOVA and Tukey's test (α=0.05). Results: At 24 h, pure extract of MTA Repair HP and Biodentine 1:16 presented higher cell viability compared to control. Lower cell viability was found for pure extract of Cimmo HD, MTA Repair HP 1:4 and 1:16, and White MTA 1:16. At 48 h, pure extract of Bio-C Repair and MTA Repair HP presented higher cell viability compared to control. At 72 h, only the pure extract of MTA Repair HP led to higher cell proliferation compared to control. Conclusion: Biodentine, Bio-C Repair and MTA Repair HP were able to induce hPDLSCs proliferation. Cimmo HD and White MTA were found to be mostly cytotoxic in hPDLSCs.

Odontología Sanmarquina, 2022

Los profesionales de la salud oral tienen un mayor riesgo de infección con el nuevo coronavirus 2... more Los profesionales de la salud oral tienen un mayor riesgo de infección con el nuevo coronavirus 2019 (COVID-19), debido a la comunicación cercana a la cavidad oral y la exposición a saliva, sangre y otros fluidos corporales. Los enfoques digitales pueden reducir el tiempo clínico y contribuir a limitar el riesgo de infección. El objetivo del presente trabajo es presentar un enfoque digital para restaurar un diente anterior traumatizado, durante la pandemia de COVID-19. Paciente sexo feminino de 28 años, con movilidad anormal de la pieza 1.1 y antecedente de traumatismo dental en la adolescencia. Se realizó una evaluación inicial para detectar signos y síntomas de una posible infección por COVID-19. Las imágenes de la tomografía computarizada mostraron fractura coronaria y presencia de reabsorción cervical externa en el incisivo central derecho. El plan de tratamiento consistió en la rehabilitación del diente fracturado a través de una restauración retenida con un poste de fibra de v...

Composite resin restoration on posterior teeth through the incremental technique is, generally, a... more Composite resin restoration on posterior teeth through the incremental technique is, generally, a time consuming procedure with risk of contamination between the layers. Therefore, It has been developed techniques to facilitate the work of dental professionals and achieve aesthetic and functional results such as the occlusal stamp technique. This technique makes the procedure faster by accurately copying the occlusal anatomy, allowing a little or no occlusal adjustment. The aim of the present study was to present a clinical case in which the stamp technique was performed and to describe the restorative treatment in a patient with hidden carie. It was observed that the stamp technique, when performed correctly, is a reliable and predictable method for the reconstruction of the occlusal anatomy.

Introducao: as cirurgias em terceiros molares retidos sao procedimentos frequentes na pratica cli... more Introducao: as cirurgias em terceiros molares retidos sao procedimentos frequentes na pratica clinica de cirurgioes-dentistas e estao associadas com inumeras complicacoes trans e pos-operatorias. Alguns autores recomendam a utilizacao de antibioticos locais e sistemicos com o intuito de prevenir essas complicacoes. Nao obstante, a profilaxia antibiotica para extracao de terceiros molares e objeto de controversias no tocante a sua eficacia com relacao a prevencao de complicacoes pos-cirurgicas onde evidencias cientificas acerca de suas vantagens e desvantagens ainda sao limitadas. Objetivo: o presente trabalho objetivou buscar na literatura vigente evidencias cientificas acerca do papel da profilaxia antibiotica para prevencao ou reducao de complicacoes infecciosas pos-operatorias no contexto das cirurgias em terceiros molares retidos em pacientes saudaveis. Metodo: para tal, realizou-se uma pesquisa bibliografica de carater exploratorio bases de dados eletronicas SciELO, PubMed, EBS...

O objetivo deste estudo foi identificar os conceitos sobre saude dos estudantes de odontologia de... more O objetivo deste estudo foi identificar os conceitos sobre saude dos estudantes de odontologia de instituicao de ensino superior bem como avaliar sob quais conceitos os estudantes estao se pautando no enfrentamento dos problemas de saude. Trata-se de um estudo descritivo de corte transversal aprovado pelo Comite de Etica em Pesquisa NOVAFAPI (Parecer 0355.0.043.000-11). A amostra da pesquisa foi composta de 200 alunos (93,46 %), sendo a maioria do genero feminino (53%), e o conceito de saude mais frequente foi de bem-estar (51,6 %) em seus diferentes aspectos. Analisando o cruzamento de tabelas, genero e abordagem dos temas sociais, houve diferenca estatisticamente significativa (p=0,042), sendo comprovado pelo teste exato de Fischer (p=0,029). A maioria dos estudantes tem saude como bem-estar, fato este relacionado a difusao do conceito da OMS.

Brazilian Dental Journal, 2021

This study investigated the effect of three commercial calcium silicate-based materials (CSBM) on... more This study investigated the effect of three commercial calcium silicate-based materials (CSBM) on cytotoxicity and pro-and anti-inflammatory cytokines production in cultured human periodontal ligament stem cells (hPDLSCs). Culture of hPDLSCs was established and characterized. Extracts of Bio-C Sealer (Angelus, Londrina, PR, Brazil), MTA Fillapex (Angelus, Londrina, PR, Brazil) and PBS Cimmo HP (Cimmo Soluções em Saúde, Pouso Alegre, MG, Brazil) were prepared by placing cement specimens (5 x 3 mm) in culture medium. Then, the extracts were serially two-fold diluted (1, 1:2, 1:4, 1:8, 1:16) and inserted into the cell-seeded wells for 24, 48 and 72 h for MTT assays. TNF-α and IL-10 cytokines were quantified by ELISA at 24h-cell supernatants. Data were analyzed by ANOVA and Tukey’s test (α = 0.05). All CSBM exhibited some cytotoxicity that varied according to extract concentration and time of evaluation. MTA Fillapex presented the highest cytotoxic effects with significant reduction of ...

Brazilian Dental Science, 2021

Introduction: Ceramic veneers represent a treatment approach in aesthetic dentistry. They are ind... more Introduction: Ceramic veneers represent a treatment approach in aesthetic dentistry. They are indicated in cases of alterations in size, contour, form and color of the teeth. The clinical and radiographic examinations may not allow the correct identification of failures in the treatment with ceramic veneers. Objective: To report the use of Optical Coherence Tomography (OCT) for the evaluation and repair of an aesthetic oral rehabilitation involving ceramic veneers. Case report: A 24-year-old female patient complained of unsatisfied color change in the ceramic veneer placed on the right maxillary central incisor. The clinical examination showed color changes between the middle and incisal thirds of mesial surface of the tooth crown. The OCT sagittal images evidenced the presence of bubbles or gaps in the adhesive interface. The treatment consisted of repair of the restoration by infiltration of a composite resin. Conclusion: The OCT was found to be valid tool to evaluate the adaptati...

RGO - Revista Gaúcha de Odontologia, 2020

Since the outbreak of the Coronavirus Disease 2019 (COVID-19), caused by the Severe Acute Respira... more Since the outbreak of the Coronavirus Disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), numerous restrictive measures have been adopted by governments of different countries. The return to elective dental care in Brazil is a reality even during the COVID-19 pandemic. During restorative dental procedures, the dental professional requires close contact with the patient, being exposed to contaminated saliva and fluids. In addition, transmission of COVID-19 by the generation of aerosol produced by dental handipieces may be possible. Thus, the dental staff must know how to act during restorative dental procedures, putting into practice the correct clinical protocols to avoid cross-contamination and COVID-19 spread. The purpose of this article is to review the literature on the biosafety practices especially in the context of restorative dental procedures in times of COVID-19.

Journal of Diabetes Science and Technology, 2020

Patients with diabetes are at increased risk of the severe course of the coronavirus disease 2019... more Patients with diabetes are at increased risk of the severe course of the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We read with great interest the article of Pfützner et al. 1 in the Journal of Diabetes Science and Technology (JDST). The authors pointed out the relationship between periodontal diseases, diabetes, and increased COVID-19 mortality. Along with the possibility of salivary gland infection, some reports on the literature have also shown hyposalivation and taste alterations in COVID-19 patients. In this letter, we would like to call the attention of the possible long-term oral consequences that individuals affected by COVID-19 may present, especially regarding diabetes. The SARS-CoV and the SARS-CoV-2 share similarities. Both viruses use angiotensin-converting enzyme 2 (ACE-2) as receptor for entry into target cells and transmembrane serine protease 2 for priming. 2 ACE-2 is expressed in several tissues, including salivary glands and pancreas. In the pancreas, the previous SARS-CoV was found to damage islets, reduce insulin release, and cause acute insulin-dependent diabetes mellitus. 3 It was reported that, after hospitalization, more than 50% of the patients with SARS-CoV infection became diabetic. 3 Interestingly, the SARS-CoV-2 infection was shown to cause ketosis or ketoacidosis and induced diabetic ketoacidosis for those with diabetes. 4 The SARS-CoV-2 could also infect and cause damage to α-cells and β-cells of the pancreas, aggravating its function. 5,6 Thus, it is possible that COVID-19 trigger diabetes in some individuals. Literature reports that patients with diabetes often present oral repercussions, including periodontal diseases and salivary gland dysfunction, among others. It is well known that oxidative stress plays an important role in diabetes. Oxidative stress has also been suggested as a link between diabetes and periodontal disease. Interestingly, literature also suggested oxidative stress as a player in COVID-19 infection. According to our group experience, the salivary glands present oxidative damage and disturbances in the metabolism and antioxidant 948041D STXXX10.

Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2020

The world is under the threat of the novel coronavirus disease 2019 (COVID-19) caused by the seve... more The world is under the threat of the novel coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Despite several efforts to contain the disease spread, it still constitutes a public health emergency of international concern. Several published reports in the scientific literature called attention of the oral cavity as the potential route of infection, the implications for dental practice and the use of saliva in the diagnose of the COVID-19. The aim of this article is to provide an overview of the literature on the salivary glands and saliva in the context of SARS-CoV-2 infection. A brief discussion of taste disturbances and oral findings in COVID-19 patients is also presented. The literature shows that SARS-CoV-2 could infect the salivary glands. It is not possible, however, to make speculations regarding them as reservoirs for the SARS-CoV-2. In addition, patients with COVID-19 presented several oral repercussions, including hyposalivation and taste disturbances. A few reports showed oral ulcers and blisters associated with SARS-CoV-2 infection. However, it remains not fully understood and might lead to erroneous assumptions. Overall, further studies are necessary to understand the real role of salivary glands and saliva in the context of SARS-CoV-2 infection.

Full Dentistry in Science, 2019

Descrever a harmonização do sorriso, através da cirurgia plástica gengival em uma condição descri... more Descrever a harmonização do sorriso, através da cirurgia plástica gengival em uma condição descrita como sorriso gengival. Detalhamento do caso: Paciente, sexo feminino, 21 anos de idade, apresentou-se na Clínica de Odontologia da FURB, insatisfeita com a estética vermelha de seu sorriso. Realizados os exames periodontais, e comprovado o status de saúde periodontal, indicou-se e a cirúrgica plástica periodontal. Modelos prévios, através de um medidor de proporcionalidade de Chu, permitiram uma correta avaliação do aumento da coroa clínica dos dentes necessário e mantendo uma proporção harmônica dos mesmos. Este ensaio, após testado na paciente através de um mockup, serviu para a montagem do planejamento cirúrgico para diminuição da estética vermelha. O controle fotográfico foi realizado antes do ato cirúrgico, no transcirúrgico, no pós operatório imediato, aos 7,14, 45, 60 e 90 dias após a realização da cirurgia. Os resultados permitiram obter um contorno gengival completamente estabelecido, arco côncavo gengival harmônico e ausência de discrepância nas curvaturas. Considerações finais: Concluiu-se que a realização da cirurgia plástica periodontal permitiu um resultado estético satisfatório com diminuição do sorriso gengival da paciente.

Brazilian Dental Science, 2018

Objective: The objective of this study was to evaluate the 6-month clinical performance of class ... more Objective: The objective of this study was to evaluate the 6-month clinical performance of class I occlusal composite resin restorations through a multicenter, randomized, double-blind, clinical trial. Material e Métodos: Two hundred and eighty class I occlusal restorations were performed in 70 patients (aged between 17 to 50 years). The restorations were divided into four groups: G1 (Filtek P60/3M ESPE); G2 (Rok/SDI); G3 (Filtek™ P90/3M ESPE); G4 (Evolux/Dentsply). Two pre-calibrated dental practitioners performed and evaluated the restorative procedures regarding to color match, marginal discoloration, recurrent caries, wear (anatomic form) and marginal integrity according to the USPHS criteria. Resultados: In 85.8% of the evaluated restorations was observed the ideal score (A) for color match; 91.4% for marginal discoloration; 100% for recurrent caries; 87.7% for wear (anatomic form) and 99.3% for marginal integrity. Conclusion: The composite resins used in this study presented ...

Revista da ABENO, 2018

O objetivo deste estudo foi avaliar o perfil de egressos do curso de graduação em Odontologia da ... more O objetivo deste estudo foi avaliar o perfil de egressos do curso de graduação em Odontologia da Universidade Federal de Pernambuco, formados no modelo curricular vigente até o ano de 2009, denominado 6404. Uma amostra de conveniência de 233 cirurgiões-dentistas graduados de 2003 a 2008 foi entrevistada individualmente com uso de formulário específico. Os dados obtidos foram tabulados e submetidos à análise estatística descritiva e inferencial (teste chi-quadrado Pearson ou teste Exato de Fisher) (α=5%). Verificou-se que 30,9% dos egressos atuavam somente como profissionais liberais, 15% apenas em cargo público e que 40,8% associavam o exercício liberal à docência, cargo público e/ou empresa privada. O grau de satisfação com a profissão mostrou-se diretamente relacionado à renda e não aos conhecimentos adquiridos. A renda foi influenciada pelo tipo de exercício profissional. Concluiu-se que os egressos possuem o perfil de um profissional preocupado com a educação continuada e que ge...

Brazilian Dental Science, 2018

Objective: To evaluate the oral health self-perception and the influence of dental treatment on t... more Objective: To evaluate the oral health self-perception and the influence of dental treatment on the multidisciplinary approach of adolescent victims of sexual abuse. Material and Methods: It was adopted a qualitative methodology that emphasized the deepening and comprehension of the answers obtained. Six adolescents, from both genders, victims of sexual abuse in the last two years, aged between 10 and 15, took part of the study. A questionnaire was applied before and after the dental treatment in order to evaluate changes in the self-perception and self-esteem of the individuals. The answers were categorized into two thematic axes with the use of the qualitative content analysis: self-perception and self-esteem. Psychological attendance prior and after the dental interventions enabled to comprehend the changes observed. Results: The participants presented a coherent self-perception in relation to the present clinical situation and an increase of their self-esteem after the dental in...