Péter Vinkler - Academia.edu (original) (raw)

Papers by Péter Vinkler

Current Science, Sep 10, 2000

In the Chemical Research Center of the Hungarian Academy of Sciences, special scientometric indic... more In the Chemical Research Center of the Hungarian Academy of Sciences, special scientometric indicators have been used for evaluating publication activity of research teams for about 30 years. Modified Garfield impact factors for journals as well as relative citedness of papers are applied as indicators because of differences among subfields in scientometric features of the publications assessed. Our experience has shown that the evaluation of real scientometric systems needs compromises among the parties interested and between the practical applicability and the theoretical requirements of scientometrics.

Evaluating Science and Scientists, 1997

Chemischer Informationsdienst, 1974

Das Sulfodiphenylpikrylhydrazin (I) reagiert in O2 ‐freier wäßriger Lösung mit etwa äquimolaren M... more Das Sulfodiphenylpikrylhydrazin (I) reagiert in O2 ‐freier wäßriger Lösung mit etwa äquimolaren Mengen von NaOH in Gegenwart von Aceton (als Elektronenakzeptor) zu einem Hydroxyderivat, für das UV‐ und IR‐spektrometrisch die Struktur (II)‐ wahrscheinlich gemacht wird.

Chemischer Informationsdienst. Organische Chemie, 1971

Die Thiocarbamide (I) reagieren mit dem Sulfenylchlorid (II) in wasserfreiem Dioxan zu den Salzen... more Die Thiocarbamide (I) reagieren mit dem Sulfenylchlorid (II) in wasserfreiem Dioxan zu den Salzen (III) (47‐86% Ausbeute).

Trace Elements and Electrolytes, 2003

Heavy metal accumulation in higher concentration may inhibit enzyme activities, modify metabolic ... more Heavy metal accumulation in higher concentration may inhibit enzyme activities, modify metabolic pathways, influence acute-phase protein synthesis and gene expression. The presence of Zn, Cu, Cd, Mn and Ni can modulate the function of tumor suppressor protein p53. DNA repair system is a sensitive target for Ni and Cr ions, consequently, the risk of tumor formation may increase. Therefore, we were interested in whether the concentration of Fe, Zn, Cu, Mn, Ni and Cr elements in liver and bile in alimentary induced fatty liver would show any alteration compared to the controls in rats. Male Wistar rats were fed with fat-rich diet (2% cholesterol, 0.5% cholic acid (CA) or deoxycholic acid (DCA) and 20% sunflower oil added to the basal diet) for 12 days. Ten rats were kept on normal chow, 10 rats were fed with DCA and 10 rats with CA. Histopathological examination was performed to evaluate the tissue degeneration. Element concentrations were determined with ICP-OES. Significant changes were detected in the concentrations of Fe and Ni in the liver, but no significant decrease in Zn, Cu and Mn contents in this short-term experiment. The fatty liver accumulated Cr and Ni whereas the concentration of Fe, Zn, Ni, Cr enhanced in the bile. Significant increase in the concentration of Ni and Fe, and non-significant one of Zn in the bile was measured. The correlation between concentrations of the d-field elements in the liver were modified except Zn and Mn in hyperlipidemy. Consequently, attention should be paid to the lipid-rich diet consumption, because it may involve risk for accumulation of toxic elements in the liver.

Trace Elements and Electrolytes, 2002

Metals in the human body are metabolized mainly via the kidney and liver and excreted through uri... more Metals in the human body are metabolized mainly via the kidney and liver and excreted through urine and partly by bile. Changes in the composition of bile may induce cholecystitis and cholelithiasis. For the study of the effect of metal elements in the bile on gallstone formation, element concentration in the gallstone (cholesterol and mixed pigment stones) and bile samples were measured. The samples were digested with a mixture of HNO 3 (5 ml) and H 2 O 2 (3 ml) in teflon vessels. The concentration of 23 elements (Al, As, B, Ba, Ca, Cd, Co, Cr, Cu, Fe, Hg, K, Li, Mg, Mn, Mo, Na, Ni, P, S, Ti, V, Zn) in the bile fluid and gallstone samples were determined by inductively coupled plasma optical emission spectrometry (ICP-OES). The concentration of Cd, Hg, Li and V in the bile and V in the gallstone samples was below the detection limit in each case. Significant correlation was found between the concentration of Al-Ca (r=0.985), P-Mg(r=0.891), S-Mg(r= 0.893) in bile and Al-Ca (r = 0.98...

Trace Elements and Electrolytes, 2004

Scientometrics

The publication activity of 20 Price-medallists was analysed by calculating several scientometric... more The publication activity of 20 Price-medallists was analysed by calculating several scientometric indices from data of elite sets of their publications. The following elite sets (i.e. most cited papers within the total) were obtained: π-set (where the number of papers is equal to √P, and P is the number of total papers), h-set (in which the number of papers equals to the Hirsch index), 2π-set, 2h-set, and the set of papers (ECP) which are cited more frequently than the average. The percentage share of papers and citations was found to increase in the mentioned rank of the elite sets, except ECP-set. The number of publications and citations in the elite sets was calculated also by different part-impact methods for sharing credit among the coauthors. The applied methods take into account the number or number and rank of coauthors in the by-line of the papers. It was demostrated that any of the methods changes both π and h-index significantly related to the value calculated by attribut...

Chemischer Informationsdienst, 1977

ChemInform Abstract Durch Pinner-Reaktion wird aus dem Hydroxybenzonitril (I) das Imidsäuresalz (... more ChemInform Abstract Durch Pinner-Reaktion wird aus dem Hydroxybenzonitril (I) das Imidsäuresalz (II) dargestellt, dessen Thiolyse mit H2S zu dem Thiosäure-O-methylester (III) führt. Das Thioimidsäureestersalz (V)-erhältlich aus (I)über das Thiobenzamid (IV)-lässt sich nicht zu o-Hydroxy-dithiobenzoesäure-S-methylester thiolysieren, aber zu dem Thioimidsäureester (VI) neutralisieren. Die Umsetzung von Benzoylcyanid (VII) mit den Alkoholen und Thiolen (VIII) nach Pinner in Gegenwart von BF3-ätherat ergibt die entsprechenden Imidsalze (IX). Bei der Thiolyse von (IXa) bzw. (IXb) entstehen nicht die erwarteten Ester (Xa) bzw. (Xb), sondern die bisher unbekannten Hydroxy-thioessigsäure-O-ester (XIa) bzw. (XIb). (IXc) wird zu (XII) hydrolysiert. Die Salze (IXd)-(IXf) lassen sich weder neutralisieren noch thiolysieren. Die IR-, Raman-und 1H-NMR-Spektren der Thionoverbindungen (III), (XIa), (XIII) und (XIV) weisen auf das Auftreten von OH...S=C-Wasserstoffbrücken hin, die bei (III) und bevorzugt bei (XIII) und der Enolform von (XIV) besonders stark sind. Die Raman-Spektren erlauben die Lokalisierung der C=S-Valenzschwingung im Bereich von 1200-1300 cm-1.

Zeitschrift für Naturforschung B, 1971

Kinetics of catalyzed acyl group exchange between acetic-1-14C anhydride and alkyl thiolacetates ... more Kinetics of catalyzed acyl group exchange between acetic-1-14C anhydride and alkyl thiolacetates was investigated. The exchange is not accompanied by chemical reaction and demonstrates the full equivalency of anhydride acyl groups in the process. The rate of exchange is lowered by increasing branching rather than lengthening in S-alkyl substituents. The role of catalyst and structures of possible intermediates are interpreted. Upon existing linear structure-reactivity relationship a common mechanism involving sulfur atom as the reaction site seems to be operative.

Patents like papers are carriers of original infonnation. Some indicators have been introduced to... more Patents like papers are carriers of original infonnation. Some indicators have been introduced to characterize patenting relations between countries. The Foreign Patent Penetration (FPP) indicator e.g. relates the percentage share of patents in a given country granted to patentees from a group of high income economies (ECP) to the total of ECP resident patents. Share of patents granted to a given country in ECP countries was related to the total of non-resident patents granted in ECP countries (FPI, Foreign Patent Integration). The indicators reveal that the patenting activity of japan is extremely high, while the interest of high income economies towards the japanese patent market is very modest Integration of the fonnerly centralized East­ European economies into the world patenting system was found to be low (except for Hungary and Poland in certain aspects) . GDP and WIP (which represents the scien­ tific infonnation production of countries) were found to be correlated with the ...

Phytotherapy Research, 1998

Atomic emission spectrometry was applied for the determination of potassium and sodium concentrat... more Atomic emission spectrometry was applied for the determination of potassium and sodium concentrations in crude drugs and decoctions. The content of the two elements and potassium-sodium ratios of medicinal plant extracts were measure as a basis for evaluating diuretic activity. The potassium-sodium ratios were higher in the diuretic plant decoctions, than in crude drug decoctions used for different activities.

Scientometrics

Several scientists publish journal papers on more than only a single scientific field or subfield... more Several scientists publish journal papers on more than only a single scientific field or subfield. However, in evaluating the impact of publications of individuals their all scientific publications are taken into account, in general. In this paper a new method, namely the part-set method is introduced for assessing papers according to the respective fields and forming a cumulative impact index. In assessing publications of scientists, elite set indicators (e.g. h-index, g-index, top percentage indices, π-index) are preferably used recently. For obtaining elite sets, we may apply inside standards, i.e. values derived from the number of papers and citations in the set analysed, or field (outside) standards taking into account the same factors referring to all papers on the corresponding field. For model calculations some scientometricians are selected who publish papers not only on scientometrics but also on other (e.g. physics, chemistry, medicine, etc.) fields. Consequently, their p...

Current Science, Sep 10, 2000

In the Chemical Research Center of the Hungarian Academy of Sciences, special scientometric indic... more In the Chemical Research Center of the Hungarian Academy of Sciences, special scientometric indicators have been used for evaluating publication activity of research teams for about 30 years. Modified Garfield impact factors for journals as well as relative citedness of papers are applied as indicators because of differences among subfields in scientometric features of the publications assessed. Our experience has shown that the evaluation of real scientometric systems needs compromises among the parties interested and between the practical applicability and the theoretical requirements of scientometrics.

Evaluating Science and Scientists, 1997

Chemischer Informationsdienst, 1974

Das Sulfodiphenylpikrylhydrazin (I) reagiert in O2 ‐freier wäßriger Lösung mit etwa äquimolaren M... more Das Sulfodiphenylpikrylhydrazin (I) reagiert in O2 ‐freier wäßriger Lösung mit etwa äquimolaren Mengen von NaOH in Gegenwart von Aceton (als Elektronenakzeptor) zu einem Hydroxyderivat, für das UV‐ und IR‐spektrometrisch die Struktur (II)‐ wahrscheinlich gemacht wird.

Chemischer Informationsdienst. Organische Chemie, 1971

Die Thiocarbamide (I) reagieren mit dem Sulfenylchlorid (II) in wasserfreiem Dioxan zu den Salzen... more Die Thiocarbamide (I) reagieren mit dem Sulfenylchlorid (II) in wasserfreiem Dioxan zu den Salzen (III) (47‐86% Ausbeute).

Trace Elements and Electrolytes, 2003

Heavy metal accumulation in higher concentration may inhibit enzyme activities, modify metabolic ... more Heavy metal accumulation in higher concentration may inhibit enzyme activities, modify metabolic pathways, influence acute-phase protein synthesis and gene expression. The presence of Zn, Cu, Cd, Mn and Ni can modulate the function of tumor suppressor protein p53. DNA repair system is a sensitive target for Ni and Cr ions, consequently, the risk of tumor formation may increase. Therefore, we were interested in whether the concentration of Fe, Zn, Cu, Mn, Ni and Cr elements in liver and bile in alimentary induced fatty liver would show any alteration compared to the controls in rats. Male Wistar rats were fed with fat-rich diet (2% cholesterol, 0.5% cholic acid (CA) or deoxycholic acid (DCA) and 20% sunflower oil added to the basal diet) for 12 days. Ten rats were kept on normal chow, 10 rats were fed with DCA and 10 rats with CA. Histopathological examination was performed to evaluate the tissue degeneration. Element concentrations were determined with ICP-OES. Significant changes were detected in the concentrations of Fe and Ni in the liver, but no significant decrease in Zn, Cu and Mn contents in this short-term experiment. The fatty liver accumulated Cr and Ni whereas the concentration of Fe, Zn, Ni, Cr enhanced in the bile. Significant increase in the concentration of Ni and Fe, and non-significant one of Zn in the bile was measured. The correlation between concentrations of the d-field elements in the liver were modified except Zn and Mn in hyperlipidemy. Consequently, attention should be paid to the lipid-rich diet consumption, because it may involve risk for accumulation of toxic elements in the liver.

Trace Elements and Electrolytes, 2002

Metals in the human body are metabolized mainly via the kidney and liver and excreted through uri... more Metals in the human body are metabolized mainly via the kidney and liver and excreted through urine and partly by bile. Changes in the composition of bile may induce cholecystitis and cholelithiasis. For the study of the effect of metal elements in the bile on gallstone formation, element concentration in the gallstone (cholesterol and mixed pigment stones) and bile samples were measured. The samples were digested with a mixture of HNO 3 (5 ml) and H 2 O 2 (3 ml) in teflon vessels. The concentration of 23 elements (Al, As, B, Ba, Ca, Cd, Co, Cr, Cu, Fe, Hg, K, Li, Mg, Mn, Mo, Na, Ni, P, S, Ti, V, Zn) in the bile fluid and gallstone samples were determined by inductively coupled plasma optical emission spectrometry (ICP-OES). The concentration of Cd, Hg, Li and V in the bile and V in the gallstone samples was below the detection limit in each case. Significant correlation was found between the concentration of Al-Ca (r=0.985), P-Mg(r=0.891), S-Mg(r= 0.893) in bile and Al-Ca (r = 0.98...

Trace Elements and Electrolytes, 2004

Scientometrics

The publication activity of 20 Price-medallists was analysed by calculating several scientometric... more The publication activity of 20 Price-medallists was analysed by calculating several scientometric indices from data of elite sets of their publications. The following elite sets (i.e. most cited papers within the total) were obtained: π-set (where the number of papers is equal to √P, and P is the number of total papers), h-set (in which the number of papers equals to the Hirsch index), 2π-set, 2h-set, and the set of papers (ECP) which are cited more frequently than the average. The percentage share of papers and citations was found to increase in the mentioned rank of the elite sets, except ECP-set. The number of publications and citations in the elite sets was calculated also by different part-impact methods for sharing credit among the coauthors. The applied methods take into account the number or number and rank of coauthors in the by-line of the papers. It was demostrated that any of the methods changes both π and h-index significantly related to the value calculated by attribut...

Chemischer Informationsdienst, 1977

ChemInform Abstract Durch Pinner-Reaktion wird aus dem Hydroxybenzonitril (I) das Imidsäuresalz (... more ChemInform Abstract Durch Pinner-Reaktion wird aus dem Hydroxybenzonitril (I) das Imidsäuresalz (II) dargestellt, dessen Thiolyse mit H2S zu dem Thiosäure-O-methylester (III) führt. Das Thioimidsäureestersalz (V)-erhältlich aus (I)über das Thiobenzamid (IV)-lässt sich nicht zu o-Hydroxy-dithiobenzoesäure-S-methylester thiolysieren, aber zu dem Thioimidsäureester (VI) neutralisieren. Die Umsetzung von Benzoylcyanid (VII) mit den Alkoholen und Thiolen (VIII) nach Pinner in Gegenwart von BF3-ätherat ergibt die entsprechenden Imidsalze (IX). Bei der Thiolyse von (IXa) bzw. (IXb) entstehen nicht die erwarteten Ester (Xa) bzw. (Xb), sondern die bisher unbekannten Hydroxy-thioessigsäure-O-ester (XIa) bzw. (XIb). (IXc) wird zu (XII) hydrolysiert. Die Salze (IXd)-(IXf) lassen sich weder neutralisieren noch thiolysieren. Die IR-, Raman-und 1H-NMR-Spektren der Thionoverbindungen (III), (XIa), (XIII) und (XIV) weisen auf das Auftreten von OH...S=C-Wasserstoffbrücken hin, die bei (III) und bevorzugt bei (XIII) und der Enolform von (XIV) besonders stark sind. Die Raman-Spektren erlauben die Lokalisierung der C=S-Valenzschwingung im Bereich von 1200-1300 cm-1.

Zeitschrift für Naturforschung B, 1971

Kinetics of catalyzed acyl group exchange between acetic-1-14C anhydride and alkyl thiolacetates ... more Kinetics of catalyzed acyl group exchange between acetic-1-14C anhydride and alkyl thiolacetates was investigated. The exchange is not accompanied by chemical reaction and demonstrates the full equivalency of anhydride acyl groups in the process. The rate of exchange is lowered by increasing branching rather than lengthening in S-alkyl substituents. The role of catalyst and structures of possible intermediates are interpreted. Upon existing linear structure-reactivity relationship a common mechanism involving sulfur atom as the reaction site seems to be operative.

Patents like papers are carriers of original infonnation. Some indicators have been introduced to... more Patents like papers are carriers of original infonnation. Some indicators have been introduced to characterize patenting relations between countries. The Foreign Patent Penetration (FPP) indicator e.g. relates the percentage share of patents in a given country granted to patentees from a group of high income economies (ECP) to the total of ECP resident patents. Share of patents granted to a given country in ECP countries was related to the total of non-resident patents granted in ECP countries (FPI, Foreign Patent Integration). The indicators reveal that the patenting activity of japan is extremely high, while the interest of high income economies towards the japanese patent market is very modest Integration of the fonnerly centralized East­ European economies into the world patenting system was found to be low (except for Hungary and Poland in certain aspects) . GDP and WIP (which represents the scien­ tific infonnation production of countries) were found to be correlated with the ...

Phytotherapy Research, 1998

Atomic emission spectrometry was applied for the determination of potassium and sodium concentrat... more Atomic emission spectrometry was applied for the determination of potassium and sodium concentrations in crude drugs and decoctions. The content of the two elements and potassium-sodium ratios of medicinal plant extracts were measure as a basis for evaluating diuretic activity. The potassium-sodium ratios were higher in the diuretic plant decoctions, than in crude drug decoctions used for different activities.

Scientometrics

Several scientists publish journal papers on more than only a single scientific field or subfield... more Several scientists publish journal papers on more than only a single scientific field or subfield. However, in evaluating the impact of publications of individuals their all scientific publications are taken into account, in general. In this paper a new method, namely the part-set method is introduced for assessing papers according to the respective fields and forming a cumulative impact index. In assessing publications of scientists, elite set indicators (e.g. h-index, g-index, top percentage indices, π-index) are preferably used recently. For obtaining elite sets, we may apply inside standards, i.e. values derived from the number of papers and citations in the set analysed, or field (outside) standards taking into account the same factors referring to all papers on the corresponding field. For model calculations some scientometricians are selected who publish papers not only on scientometrics but also on other (e.g. physics, chemistry, medicine, etc.) fields. Consequently, their p...