Profect Chen - Academia.edu (original) (raw)

Papers by Profect Chen

The finite-difference time-domain (FDTD) method of solving the full-wave Maxwell&amp;#x27... more The finite-difference time-domain (FDTD) method of solving the full-wave Maxwell&amp;#x27;s equations has been recently extended to provide accurate and numerically stable operation for time steps exceeding the Courant limit. The elimination of an upper bound on the size of the time step was achieved using an alternating-implicit direction (ADI) time-stepping scheme. This greatly increases the computational efficiency of the FDTD method for classes of problems where the cell size of the three-dimensional space lattice is constrained to be much smaller than the shortest wavelength in the source spectrum. One such class of problems is the analysis of high-speed VLSI interconnects where full-wave methods are often needed for the accurate analysis of parasitic electromagnetic wave phenomena. In this paper, we present an enhanced FDTD-ADI formulation which permits the modeling of realistic lossy materials such as semiconductor substrates and metal conductors as well as artificial lossy materials needed for perfectly matched layer (PML) absorbing boundary conditions. Simulations using our generalized FDTD-ADI formulation are presented to demonstrate the accuracy and extent to which the computational burden is reduced by the ADI scheme.

Pacific Asia Journal of the Association For Information Systems, 2013

Ieee Transactions on Advanced Packaging, Feb 1, 2010

Journal of Nuclear Medicine, Jun 1, 1997

Microelectronic Engineering, Apr 1, 2009

Page 1. Be Careful of Self and Mutual Inductance Formulae Hyungsuk Kim Dept. of Electrical and Co... more Page 1. Be Careful of Self and Mutual Inductance Formulae Hyungsuk Kim Dept. of Electrical and Computer Engineering Univ. of Wisconsin - Madison hyungsuk@cae.wisc.edu Charlie Chung-Ping Chen Dept. of Electrical and Computer Engineering Univ. ...

Knowledge Management Research Practice, 2010

$Research paper thumbnail of A squared magnitude continued fraction expansion for stable reduced models$

Molecular Pharmacology, 1996

Protein kinase C (PKC), the major receptor for tumor-promoting phorbol esters, is a family consis... more Protein kinase C (PKC), the major receptor for tumor-promoting phorbol esters, is a family consisting of at least 12 distinct isoforms. In C6 glioma cells, short term (10 min) treatment with 12-O-tetradecanoyl phorbol-13-acetate (TPA) results in a dose-dependent translocation of PKC alpha, PKC delta and PKC theta. Long term (24 hr) treatment with appropriate doses of TPA results in the complete down-regulation of PKC delta but not of PKC alpha PKC theta. This property was used to determine which isoform might be involved in the activation of the glial cell Na(+)-H+ exchanger. It was found that (a) TPA has dose-dependent effects on PKC alpha, PKC delta, and PKC theta translocation and on Na(+)-dependent, EIPA-sensitive Na(+)-H+ exchanger stimulation; (b) the antiporter is blocked both by staurosporine and in cells in which PKC alpha, PKC delta, and PKC theta have been completely down-regulated; (c) the inactive form (alpha-TPA) of TPA, which does not include translocation of the three isoforms (alpha, delta, and theta) has no effect on the antiporter; (d) Western blot analysis demonstrated dose-dependent TPA (10, 30, 100, and 1000 nM)-induced translocation of PKC alpha, PKC delta, and PKC theta. TPA (10, 30, 100, and 1000 nM)-induced Na(+)-H+ exchanger activation was also found to be dose dependent. There was no difference in TPA-induced Na(+)-H+ exchanger activation between 30 and 100 nM; it correlated with the extent of TPA-induced PKC delta translocation over the same concentration range, suggesting that isoform responsible for the exchanger activation is PKC delta; (e) When 1 microM TPA is added after prior treatment of the cells with 10 nM TPA, an additive effect on Na(+)-H+ exchanger is seen that is not observed when the initial stimulus in 30 nM TPA, as would be expected if the PKC delta isoform were responsible for exchanger activation; (f) Finally, when PKC delta, but not PKC alpha and PKC theta, is completely down-regulated by 24-hr pretreatment with 10, 30, or 100 nM TPA, the Na(+)-H+ exchanger can no longer be stimulated by 1 microM TPA; when 1 nM TPA pretreatment is used, no down-regulation occurs and the exchanger still responds to 1 microM TPA. We have shown that the Na(+)-H+ exchanger in C6 glioma cells can be stimulated by TPA-induced PKC activation and, for the first time, that PKC delta is involved in the activation of this antiporter. Our results also suggest that different members of the PKC family within a single cell elicit specific physiological responses.

Proceedings of Spie the International Society For Optical Engineering, Mar 1, 2009

In the year of 1873, Professor E. Abbe, cooperating with Carl Zeiss Inc, summarized his discovery... more In the year of 1873, Professor E. Abbe, cooperating with Carl Zeiss Inc, summarized his discovery of the microscope imaging principle which states that the final image is the superposition result of all the diffracted images entering at different angles oblique to the pupil. This discovery forms the foundation analytical methods to analyze optics resolving power. Later, in 1951, the

Journal of the Physical Society of Japan, Apr 15, 1975

Page 1. Journal of the Physical Society of Japan, Vol. 38, No. 4, April, 1975 Calculation of the ... more Page 1. Journal of the Physical Society of Japan, Vol. 38, No. 4, April, 1975 Calculation of the Electronic Density of States and the Electric Conductivity of Random Alloys in the Coherent Potential Approximation Tohru Morita, Tsuyoshi ...

International Journal of Innovation and Learning, Mar 20, 2015

ABSTRACT Today, more than ever before, innovation is a key to gain a competitive advantage and to... more ABSTRACT Today, more than ever before, innovation is a key to gain a competitive advantage and to provide a means for future growth. Many companies become industry leaders because of innovation. Radio-Frequency Identification (RFID) technology provides a way for companies to affect innovations both internally and externally. Through a review of both academic and applied literature, this paper investigates how the use of RFID can help to achieve different benefits. It presents a model of use and addresses the innovative paths that companies can take in leveraging RFID technology.

Abstract The soaring clocking frequency and integration density demand robust and stable power d... more Abstract The soaring clocking frequency and integration density demand robust and stable power delivery to support tens of millions of transistor switching. In this paper, we consider the problem of mini-mizing the area of wires and decoupling capacitors (decaps) for a power ...

Amcis 2005 Proceedings, 2005

International Journal of Production Research, 1996