Profect Chen - Academia.edu (original) (raw)

Papers by Profect Chen

Research paper thumbnail of Analysis of the Influence of Organic Corrosion Inhibitors on Corrosion of Reinforcement in Concrete Bridge Structure Under Simulated Field Service Environment

For concrete bridge projects in marine environments, attention must be paid to the reinforcement ... more For concrete bridge projects in marine environments, attention must be paid to the reinforcement corrosion problems caused by chloride intrusion. As kinds of functional admixtures, which can reduce the reinforcement corrosion rate, corrosion inhibitors are becoming very popular in China in new bridge projects. Corrosion inhibitors cover both inorganic and organic inhibitors. Nitrite is representative of inorganic corrosion inhibitors, but its carcinogenicity has hindered its further development. Organic corrosion inhibitors such as small-molecule-based alcohol amine series are becoming the focus of attention. To guide the scientific applications of organic corrosion inhibitors, China is carrying out broad applications technology research. But the evaluation of the influence of organic corrosion inhibitors on the behavior of reinforcement corrosion is mostly carried out in simulated liquids. This method simplifies the actual service environment but ignores the concrete protective layer, the form of chloride intrusion, and environmental effects, which must be considered for the application of organic corrosion inhibitor technology in practical engineering. The experimental work of this paper was conducted on a coastal bridge named Guan He Bridge in China. The influence of organic corrosion inhibitors on the reinforcement corrosion behavior in the concrete bridge structure was investigated considering the conditions of concrete protective layer change, form of chloride intrusion, and different environments through laboratory simulations. Actions and effects of organic corrosion inhibitors were comprehensively evaluated, thereby enriching the application field of organic corrosion inhibitors.

Research paper thumbnail of Generalized FDTD-ADI: An Unconditionally Stable Full-Wave Maxwell's Equations

The finite-difference time-domain (FDTD) method of solving the full-wave Maxwell&#x27... more The finite-difference time-domain (FDTD) method of solving the full-wave Maxwell's equations has been recently extended to provide accurate and numerically stable operation for time steps exceeding the Courant limit. The elimination of an upper bound on the size of the time step was achieved using an alternating-implicit direction (ADI) time-stepping scheme. This greatly increases the computational efficiency of the FDTD method for classes of problems where the cell size of the three-dimensional space lattice is constrained to be much smaller than the shortest wavelength in the source spectrum. One such class of problems is the analysis of high-speed VLSI interconnects where full-wave methods are often needed for the accurate analysis of parasitic electromagnetic wave phenomena. In this paper, we present an enhanced FDTD-ADI formulation which permits the modeling of realistic lossy materials such as semiconductor substrates and metal conductors as well as artificial lossy materials needed for perfectly matched layer (PML) absorbing boundary conditions. Simulations using our generalized FDTD-ADI formulation are presented to demonstrate the accuracy and extent to which the computational burden is reduced by the ADI scheme.

Research paper thumbnail of Enhancing Organizational Fit Factors to Achieve ERP Project Success

Pacific Asia Journal of the Association For Information Systems, 2013

Organizational fit is an important project success factor; however, its importance and relationsh... more Organizational fit is an important project success factor; however, its importance and relationships with key project management (PM) factors in large-scale software projects have not been thoroughly investigated. The purpose of this paper is to investigate of the direct effect of organizational fit factor on ERP project success,and the moderating effect of organizational adaptation and PM factors on the relationship between organizational fit and ERP success. A total of 69 enterprisesin Taiwan were surveyed. The collected data were analyzed using the regression analysis. The data analysis results indicate that organizational fit has a direct and positive influence on ERP project success. Depends on project success measures (cost, time, performance, and benefit) to achieve, organization adaptation factors (i.e. system and business process adaptation) and key PM factors (i.e. teamwork, top management support, end-user training, and vendor's advising capability)play strong moderating roles in the relationship between organizational fit and ERP success. These findings lead to academic and practical implications on improving ERP project success via managing these key factors.

Research paper thumbnail of LTCC Spiral Inductor Synthesis and Optimization With Measurement Verification

Ieee Transactions on Advanced Packaging, Feb 1, 2010

In RF/microwave circuit design, inductor design is one of the most difficult and time-consuming t... more In RF/microwave circuit design, inductor design is one of the most difficult and time-consuming tasks due to the tedious trial-and-error optimization process to achieve the target specifications such as inductance, quality factor and occupied space. This paper brings forward a fast spiral inductor synthesis method, which automatically generates physical layout of inductors according to electrical specifications. By fusion of substrate-aware partial element equivalent circuit (PEEC) model with nonlinear optimization engine, our modeling and synthesis strategies have been verified with industrial field solver and measurement results. Our calculation results got less than 7% error for inductance and less than 9% for quality factor as compared to the results from full-wave electromagnetic simulation software. This can provide a fast and good initial inductor design for designer.

Research paper thumbnail of Comparison of parathyroid imaging with technetium-99m-pertechnetate/sestamibi subtraction, double-phase technetium-99m-sestamibi and technetium-99m-sestamibi SPECT

Journal of Nuclear Medicine, Jun 1, 1997

netate images was 72%-75%, late images and pertechnetate images was 73%-78% and double-phase (ear... more netate images was 72%-75%, late images and pertechnetate images was 73%-78% and double-phase (early and late) sestamibi images was 62%-65%; computer subtraction of pertechnetate from early images was 71%-74%; and SPECT imaging was 79%. The sensitiv ity for parathyroid adenomas was 89%-98%, while the sensitivity for hyperplastic parathyroid glands was only 47%-58%. Conclusion: Late imaging, computer subtraction and SPECT may not be neces sary since they provided only marginal improvements on visual comparison of early sestamibi with pertechnetate images. Doublephase sestamibi imaging was less sensitive, so baseline thyroid imaging with pertechnetate is recommended.

Research paper thumbnail of Efficient and accurate optical scatterometry diagnosis of grating variation based on segmented moment matching and singular value decomposition method

Microelectronic Engineering, Apr 1, 2009

To ensure the quality of the nanoimprint fabricated optical gratings, optical scatterometry (OS) ... more To ensure the quality of the nanoimprint fabricated optical gratings, optical scatterometry (OS) is an efficient and effective mean to diagnose the actual fabricated geometry. To facilitate the diagnosis process, efficient pattern matching algorithms over a huge database are of great importance.

Research paper thumbnail of Be Careful of Self and Mutual Inductance Formulae

Page 1. Be Careful of Self and Mutual Inductance Formulae Hyungsuk Kim Dept. of Electrical and Co... more Page 1. Be Careful of Self and Mutual Inductance Formulae Hyungsuk Kim Dept. of Electrical and Computer Engineering Univ. of Wisconsin - Madison hyungsuk@cae.wisc.edu Charlie Chung-Ping Chen Dept. of Electrical and Computer Engineering Univ. ...

Research paper thumbnail of The Efficacy of Knowledge Map in Object-Oriented Software Training: ADO.NET Components

Knowledge Management Research Practice, 2010

An experimental study examined effects of knowledge map-based learning, a form of computer assist... more An experimental study examined effects of knowledge map-based learning, a form of computer assisted instruction (CAI), on assisting novice users in acquiring software knowledge and skills. Fifty five subjects participated in this experimental study. Two classes of students in a webpage development course were randomly chosen to receive different treatments. Twenty four students received the knowledge map-based training, while thirty one students received the traditional face-to-face training. Target software acquired by students in this study is ASP.NET. This study focuses on the data-access component ADO.NET (ActiveX Data Objects) of this target software. ADO.NET is a database access component and allows users to interact with database systems from browsers. A pre-test and post-test was administered to assess the effect of knowledge map-based learning on learning outcomes, with the traditional F2F training group as a controllable group. Results showed that students who receive the knowledge map-based training slightly outperformed those students who receive the traditional face-to-face training. Statistical evidences show that both training approaches are effective to help students acquire object-oriented software, such as ADO.NET, based on the mean scores of pre-and post-tests. Recommendations were made to instructor and practitioners to improve the efficacy of knowledge map-based training.

Research paper thumbnail of A squared magnitude continued fraction expansion for stable reduced models

Research paper thumbnail of Protein kinase C isoform delta is involved in the stimulation of the Na(+)-H+ exchanger in C6 glioma cells

Molecular Pharmacology, 1996

Protein kinase C (PKC), the major receptor for tumor-promoting phorbol esters, is a family consis... more Protein kinase C (PKC), the major receptor for tumor-promoting phorbol esters, is a family consisting of at least 12 distinct isoforms. In C6 glioma cells, short term (10 min) treatment with 12-O-tetradecanoyl phorbol-13-acetate (TPA) results in a dose-dependent translocation of PKC alpha, PKC delta and PKC theta. Long term (24 hr) treatment with appropriate doses of TPA results in the complete down-regulation of PKC delta but not of PKC alpha PKC theta. This property was used to determine which isoform might be involved in the activation of the glial cell Na(+)-H+ exchanger. It was found that (a) TPA has dose-dependent effects on PKC alpha, PKC delta, and PKC theta translocation and on Na(+)-dependent, EIPA-sensitive Na(+)-H+ exchanger stimulation; (b) the antiporter is blocked both by staurosporine and in cells in which PKC alpha, PKC delta, and PKC theta have been completely down-regulated; (c) the inactive form (alpha-TPA) of TPA, which does not include translocation of the three isoforms (alpha, delta, and theta) has no effect on the antiporter; (d) Western blot analysis demonstrated dose-dependent TPA (10, 30, 100, and 1000 nM)-induced translocation of PKC alpha, PKC delta, and PKC theta. TPA (10, 30, 100, and 1000 nM)-induced Na(+)-H+ exchanger activation was also found to be dose dependent. There was no difference in TPA-induced Na(+)-H+ exchanger activation between 30 and 100 nM; it correlated with the extent of TPA-induced PKC delta translocation over the same concentration range, suggesting that isoform responsible for the exchanger activation is PKC delta; (e) When 1 microM TPA is added after prior treatment of the cells with 10 nM TPA, an additive effect on Na(+)-H+ exchanger is seen that is not observed when the initial stimulus in 30 nM TPA, as would be expected if the PKC delta isoform were responsible for exchanger activation; (f) Finally, when PKC delta, but not PKC alpha and PKC theta, is completely down-regulated by 24-hr pretreatment with 10, 30, or 100 nM TPA, the Na(+)-H+ exchanger can no longer be stimulated by 1 microM TPA; when 1 nM TPA pretreatment is used, no down-regulation occurs and the exchanger still responds to 1 microM TPA. We have shown that the Na(+)-H+ exchanger in C6 glioma cells can be stimulated by TPA-induced PKC activation and, for the first time, that PKC delta is involved in the activation of this antiporter. Our results also suggest that different members of the PKC family within a single cell elicit specific physiological responses.

Research paper thumbnail of Abbe-PCA (Abbe-Hopkins): microlithography aerial image analytical compact kernel generation based on principle component analysis

Proceedings of Spie the International Society For Optical Engineering, Mar 1, 2009

In the year of 1873, Professor E. Abbe, cooperating with Carl Zeiss Inc, summarized his discovery... more In the year of 1873, Professor E. Abbe, cooperating with Carl Zeiss Inc, summarized his discovery of the microscope imaging principle which states that the final image is the superposition result of all the diffracted images entering at different angles oblique to the pupil. This discovery forms the foundation analytical methods to analyze optics resolving power. Later, in 1951, the

Research paper thumbnail of Effects of catalytic mineral matter on CO/COâ temperature and burning time for char combustion. Quarterly progress report No. 13, October--December 1992

Research paper thumbnail of Calculation of the Electronic Density of States and the Electric Conductivity of Random Alloys in the Coherent Potential Approximation

Journal of the Physical Society of Japan, Apr 15, 1975

Page 1. Journal of the Physical Society of Japan, Vol. 38, No. 4, April, 1975 Calculation of the ... more Page 1. Journal of the Physical Society of Japan, Vol. 38, No. 4, April, 1975 Calculation of the Electronic Density of States and the Electric Conductivity of Random Alloys in the Coherent Potential Approximation Tohru Morita, Tsuyoshi ...

Research paper thumbnail of A conceptual model of innovative applications of RFID

International Journal of Innovation and Learning, Mar 20, 2015

ABSTRACT Today, more than ever before, innovation is a key to gain a competitive advantage and to... more ABSTRACT Today, more than ever before, innovation is a key to gain a competitive advantage and to provide a means for future growth. Many companies become industry leaders because of innovation. Radio-Frequency Identification (RFID) technology provides a way for companies to affect innovations both internally and externally. Through a review of both academic and applied literature, this paper investigates how the use of RFID can help to achieve different benefits. It presents a model of use and addresses the innovative paths that companies can take in leveraging RFID technology.

Research paper thumbnail of Wireless Sensor Network for Flexible pH Array Sensor

Research paper thumbnail of Natural Ventilation Performance in Kitchens with Transoms Replaced with Porous Screens

This study was aimed to analyse the ventilation efficiency and indoor air quality in the conventi... more This study was aimed to analyse the ventilation efficiency and indoor air quality in the conventional kitchens, when porous screens were installed on the transoms. Numerical simulations and laboratory full-scale experiments were carried out in the model kitchen in the Department of Architecture at National Cheng-Kung University. The influences of porous screens on the temperature fields, flow structures and ventilation rates were indicated. The "Tracer-gas Concentration Decay" method was conducted to measure the air exchange rate and the age of air in the model kitchen. Computational Fluid Dynamics (CFD) numerical simulations were also utilized to reveal the temperature and flow distributions in detail. It was found out the interrogatives and its relevant improvement strategies.

Research paper thumbnail of Simultaneous area minimization and decaps insertion for power delivery network using adjoint senstivity analysis with ieks method

Abstract— The soaring clocking frequency and integration density demand robust and stable power d... more Abstract— The soaring clocking frequency and integration density demand robust and stable power delivery to support tens of millions of transistor switching. In this paper, we consider the problem of mini-mizing the area of wires and decoupling capacitors (decaps) for a power ...

Research paper thumbnail of Virtual Group Learning Effectiveness via eLearning Mediums

Amcis 2005 Proceedings, 2005

Online learning provides the potential for more differentiated, integrated, and open learning env... more Online learning provides the potential for more differentiated, integrated, and open learning environments to solve team project assignments. We argue that although it is feasible to increase information richness via adopting multimedia technologies, the effectiveness to promote interpersonal skills, critical thinking, and cognitive learning processes via virtual group discussion is uncertain. To substantiate the argument, we invited 156 subjects, divided into 46 groups, to resolve decision-and intellective-tasks in text-messaging and audio-conferencing e-learning environments. A pedagogical interpretation of how we can use these two e-learning systems to improve effectiveness for group-based tasks was posited.

Research paper thumbnail of Virtual Factories and Dynamic Core Competency: A Case Study of Advanced Semiconductor Engineering

Due to globalization, advanced information and communication technology has fuelled competition, ... more Due to globalization, advanced information and communication technology has fuelled competition, and building and sustaining of competition advantages are major concerns of companies. Developing dynamic core competency has become a new competition strategy and an important way to help companies remain flexible and able to respond quickly to unpredicted changes in the environment. The development of dynamic core competences requires accumulation of technology and skill over time. In turn, companies can exploit these invisible assets to develop new products and new markets and to out-compete competitors. The Internet could provide value-added service to allow companies to communicate with each other. As such, the Internet-based virtual factory had been implemented to facilitate connections among partners. Taiwan based company Advanced Semiconductor Engineering (ASE), one of the world's largest integrated circuit assembly and testing manufacturers, has constructed its virtual IC factory to strengthen bonds with upstream customers. Customers are able to directly access ASE's information system and thereby receive immediate status reports of their orders or other types of feedback. In this paper, the framework of ASE's virtual IC factory is introduced, and the competitive advantages resulted from this virtual factory are investigated. Implications of ASE's experience are then discussed.

Research paper thumbnail of Identifying attributes for knowledge-based development in dynamic scheduling environments

International Journal of Production Research, 1996

Research paper thumbnail of Analysis of the Influence of Organic Corrosion Inhibitors on Corrosion of Reinforcement in Concrete Bridge Structure Under Simulated Field Service Environment

For concrete bridge projects in marine environments, attention must be paid to the reinforcement ... more For concrete bridge projects in marine environments, attention must be paid to the reinforcement corrosion problems caused by chloride intrusion. As kinds of functional admixtures, which can reduce the reinforcement corrosion rate, corrosion inhibitors are becoming very popular in China in new bridge projects. Corrosion inhibitors cover both inorganic and organic inhibitors. Nitrite is representative of inorganic corrosion inhibitors, but its carcinogenicity has hindered its further development. Organic corrosion inhibitors such as small-molecule-based alcohol amine series are becoming the focus of attention. To guide the scientific applications of organic corrosion inhibitors, China is carrying out broad applications technology research. But the evaluation of the influence of organic corrosion inhibitors on the behavior of reinforcement corrosion is mostly carried out in simulated liquids. This method simplifies the actual service environment but ignores the concrete protective layer, the form of chloride intrusion, and environmental effects, which must be considered for the application of organic corrosion inhibitor technology in practical engineering. The experimental work of this paper was conducted on a coastal bridge named Guan He Bridge in China. The influence of organic corrosion inhibitors on the reinforcement corrosion behavior in the concrete bridge structure was investigated considering the conditions of concrete protective layer change, form of chloride intrusion, and different environments through laboratory simulations. Actions and effects of organic corrosion inhibitors were comprehensively evaluated, thereby enriching the application field of organic corrosion inhibitors.

Research paper thumbnail of Generalized FDTD-ADI: An Unconditionally Stable Full-Wave Maxwell's Equations

The finite-difference time-domain (FDTD) method of solving the full-wave Maxwell&#x27... more The finite-difference time-domain (FDTD) method of solving the full-wave Maxwell's equations has been recently extended to provide accurate and numerically stable operation for time steps exceeding the Courant limit. The elimination of an upper bound on the size of the time step was achieved using an alternating-implicit direction (ADI) time-stepping scheme. This greatly increases the computational efficiency of the FDTD method for classes of problems where the cell size of the three-dimensional space lattice is constrained to be much smaller than the shortest wavelength in the source spectrum. One such class of problems is the analysis of high-speed VLSI interconnects where full-wave methods are often needed for the accurate analysis of parasitic electromagnetic wave phenomena. In this paper, we present an enhanced FDTD-ADI formulation which permits the modeling of realistic lossy materials such as semiconductor substrates and metal conductors as well as artificial lossy materials needed for perfectly matched layer (PML) absorbing boundary conditions. Simulations using our generalized FDTD-ADI formulation are presented to demonstrate the accuracy and extent to which the computational burden is reduced by the ADI scheme.

Research paper thumbnail of Enhancing Organizational Fit Factors to Achieve ERP Project Success

Pacific Asia Journal of the Association For Information Systems, 2013

Organizational fit is an important project success factor; however, its importance and relationsh... more Organizational fit is an important project success factor; however, its importance and relationships with key project management (PM) factors in large-scale software projects have not been thoroughly investigated. The purpose of this paper is to investigate of the direct effect of organizational fit factor on ERP project success,and the moderating effect of organizational adaptation and PM factors on the relationship between organizational fit and ERP success. A total of 69 enterprisesin Taiwan were surveyed. The collected data were analyzed using the regression analysis. The data analysis results indicate that organizational fit has a direct and positive influence on ERP project success. Depends on project success measures (cost, time, performance, and benefit) to achieve, organization adaptation factors (i.e. system and business process adaptation) and key PM factors (i.e. teamwork, top management support, end-user training, and vendor's advising capability)play strong moderating roles in the relationship between organizational fit and ERP success. These findings lead to academic and practical implications on improving ERP project success via managing these key factors.

Research paper thumbnail of LTCC Spiral Inductor Synthesis and Optimization With Measurement Verification

Ieee Transactions on Advanced Packaging, Feb 1, 2010

In RF/microwave circuit design, inductor design is one of the most difficult and time-consuming t... more In RF/microwave circuit design, inductor design is one of the most difficult and time-consuming tasks due to the tedious trial-and-error optimization process to achieve the target specifications such as inductance, quality factor and occupied space. This paper brings forward a fast spiral inductor synthesis method, which automatically generates physical layout of inductors according to electrical specifications. By fusion of substrate-aware partial element equivalent circuit (PEEC) model with nonlinear optimization engine, our modeling and synthesis strategies have been verified with industrial field solver and measurement results. Our calculation results got less than 7% error for inductance and less than 9% for quality factor as compared to the results from full-wave electromagnetic simulation software. This can provide a fast and good initial inductor design for designer.

Research paper thumbnail of Comparison of parathyroid imaging with technetium-99m-pertechnetate/sestamibi subtraction, double-phase technetium-99m-sestamibi and technetium-99m-sestamibi SPECT

Journal of Nuclear Medicine, Jun 1, 1997

netate images was 72%-75%, late images and pertechnetate images was 73%-78% and double-phase (ear... more netate images was 72%-75%, late images and pertechnetate images was 73%-78% and double-phase (early and late) sestamibi images was 62%-65%; computer subtraction of pertechnetate from early images was 71%-74%; and SPECT imaging was 79%. The sensitiv ity for parathyroid adenomas was 89%-98%, while the sensitivity for hyperplastic parathyroid glands was only 47%-58%. Conclusion: Late imaging, computer subtraction and SPECT may not be neces sary since they provided only marginal improvements on visual comparison of early sestamibi with pertechnetate images. Doublephase sestamibi imaging was less sensitive, so baseline thyroid imaging with pertechnetate is recommended.

Research paper thumbnail of Efficient and accurate optical scatterometry diagnosis of grating variation based on segmented moment matching and singular value decomposition method

Microelectronic Engineering, Apr 1, 2009

To ensure the quality of the nanoimprint fabricated optical gratings, optical scatterometry (OS) ... more To ensure the quality of the nanoimprint fabricated optical gratings, optical scatterometry (OS) is an efficient and effective mean to diagnose the actual fabricated geometry. To facilitate the diagnosis process, efficient pattern matching algorithms over a huge database are of great importance.

Research paper thumbnail of Be Careful of Self and Mutual Inductance Formulae

Page 1. Be Careful of Self and Mutual Inductance Formulae Hyungsuk Kim Dept. of Electrical and Co... more Page 1. Be Careful of Self and Mutual Inductance Formulae Hyungsuk Kim Dept. of Electrical and Computer Engineering Univ. of Wisconsin - Madison hyungsuk@cae.wisc.edu Charlie Chung-Ping Chen Dept. of Electrical and Computer Engineering Univ. ...

Research paper thumbnail of The Efficacy of Knowledge Map in Object-Oriented Software Training: ADO.NET Components

Knowledge Management Research Practice, 2010

An experimental study examined effects of knowledge map-based learning, a form of computer assist... more An experimental study examined effects of knowledge map-based learning, a form of computer assisted instruction (CAI), on assisting novice users in acquiring software knowledge and skills. Fifty five subjects participated in this experimental study. Two classes of students in a webpage development course were randomly chosen to receive different treatments. Twenty four students received the knowledge map-based training, while thirty one students received the traditional face-to-face training. Target software acquired by students in this study is ASP.NET. This study focuses on the data-access component ADO.NET (ActiveX Data Objects) of this target software. ADO.NET is a database access component and allows users to interact with database systems from browsers. A pre-test and post-test was administered to assess the effect of knowledge map-based learning on learning outcomes, with the traditional F2F training group as a controllable group. Results showed that students who receive the knowledge map-based training slightly outperformed those students who receive the traditional face-to-face training. Statistical evidences show that both training approaches are effective to help students acquire object-oriented software, such as ADO.NET, based on the mean scores of pre-and post-tests. Recommendations were made to instructor and practitioners to improve the efficacy of knowledge map-based training.

Research paper thumbnail of A squared magnitude continued fraction expansion for stable reduced models

Research paper thumbnail of Protein kinase C isoform delta is involved in the stimulation of the Na(+)-H+ exchanger in C6 glioma cells

Molecular Pharmacology, 1996

Protein kinase C (PKC), the major receptor for tumor-promoting phorbol esters, is a family consis... more Protein kinase C (PKC), the major receptor for tumor-promoting phorbol esters, is a family consisting of at least 12 distinct isoforms. In C6 glioma cells, short term (10 min) treatment with 12-O-tetradecanoyl phorbol-13-acetate (TPA) results in a dose-dependent translocation of PKC alpha, PKC delta and PKC theta. Long term (24 hr) treatment with appropriate doses of TPA results in the complete down-regulation of PKC delta but not of PKC alpha PKC theta. This property was used to determine which isoform might be involved in the activation of the glial cell Na(+)-H+ exchanger. It was found that (a) TPA has dose-dependent effects on PKC alpha, PKC delta, and PKC theta translocation and on Na(+)-dependent, EIPA-sensitive Na(+)-H+ exchanger stimulation; (b) the antiporter is blocked both by staurosporine and in cells in which PKC alpha, PKC delta, and PKC theta have been completely down-regulated; (c) the inactive form (alpha-TPA) of TPA, which does not include translocation of the three isoforms (alpha, delta, and theta) has no effect on the antiporter; (d) Western blot analysis demonstrated dose-dependent TPA (10, 30, 100, and 1000 nM)-induced translocation of PKC alpha, PKC delta, and PKC theta. TPA (10, 30, 100, and 1000 nM)-induced Na(+)-H+ exchanger activation was also found to be dose dependent. There was no difference in TPA-induced Na(+)-H+ exchanger activation between 30 and 100 nM; it correlated with the extent of TPA-induced PKC delta translocation over the same concentration range, suggesting that isoform responsible for the exchanger activation is PKC delta; (e) When 1 microM TPA is added after prior treatment of the cells with 10 nM TPA, an additive effect on Na(+)-H+ exchanger is seen that is not observed when the initial stimulus in 30 nM TPA, as would be expected if the PKC delta isoform were responsible for exchanger activation; (f) Finally, when PKC delta, but not PKC alpha and PKC theta, is completely down-regulated by 24-hr pretreatment with 10, 30, or 100 nM TPA, the Na(+)-H+ exchanger can no longer be stimulated by 1 microM TPA; when 1 nM TPA pretreatment is used, no down-regulation occurs and the exchanger still responds to 1 microM TPA. We have shown that the Na(+)-H+ exchanger in C6 glioma cells can be stimulated by TPA-induced PKC activation and, for the first time, that PKC delta is involved in the activation of this antiporter. Our results also suggest that different members of the PKC family within a single cell elicit specific physiological responses.

Research paper thumbnail of Abbe-PCA (Abbe-Hopkins): microlithography aerial image analytical compact kernel generation based on principle component analysis

Proceedings of Spie the International Society For Optical Engineering, Mar 1, 2009

In the year of 1873, Professor E. Abbe, cooperating with Carl Zeiss Inc, summarized his discovery... more In the year of 1873, Professor E. Abbe, cooperating with Carl Zeiss Inc, summarized his discovery of the microscope imaging principle which states that the final image is the superposition result of all the diffracted images entering at different angles oblique to the pupil. This discovery forms the foundation analytical methods to analyze optics resolving power. Later, in 1951, the

Research paper thumbnail of Effects of catalytic mineral matter on CO/COâ temperature and burning time for char combustion. Quarterly progress report No. 13, October--December 1992

Research paper thumbnail of Calculation of the Electronic Density of States and the Electric Conductivity of Random Alloys in the Coherent Potential Approximation

Journal of the Physical Society of Japan, Apr 15, 1975

Page 1. Journal of the Physical Society of Japan, Vol. 38, No. 4, April, 1975 Calculation of the ... more Page 1. Journal of the Physical Society of Japan, Vol. 38, No. 4, April, 1975 Calculation of the Electronic Density of States and the Electric Conductivity of Random Alloys in the Coherent Potential Approximation Tohru Morita, Tsuyoshi ...

Research paper thumbnail of A conceptual model of innovative applications of RFID

International Journal of Innovation and Learning, Mar 20, 2015

ABSTRACT Today, more than ever before, innovation is a key to gain a competitive advantage and to... more ABSTRACT Today, more than ever before, innovation is a key to gain a competitive advantage and to provide a means for future growth. Many companies become industry leaders because of innovation. Radio-Frequency Identification (RFID) technology provides a way for companies to affect innovations both internally and externally. Through a review of both academic and applied literature, this paper investigates how the use of RFID can help to achieve different benefits. It presents a model of use and addresses the innovative paths that companies can take in leveraging RFID technology.

Research paper thumbnail of Wireless Sensor Network for Flexible pH Array Sensor

Research paper thumbnail of Natural Ventilation Performance in Kitchens with Transoms Replaced with Porous Screens

This study was aimed to analyse the ventilation efficiency and indoor air quality in the conventi... more This study was aimed to analyse the ventilation efficiency and indoor air quality in the conventional kitchens, when porous screens were installed on the transoms. Numerical simulations and laboratory full-scale experiments were carried out in the model kitchen in the Department of Architecture at National Cheng-Kung University. The influences of porous screens on the temperature fields, flow structures and ventilation rates were indicated. The "Tracer-gas Concentration Decay" method was conducted to measure the air exchange rate and the age of air in the model kitchen. Computational Fluid Dynamics (CFD) numerical simulations were also utilized to reveal the temperature and flow distributions in detail. It was found out the interrogatives and its relevant improvement strategies.

Research paper thumbnail of Simultaneous area minimization and decaps insertion for power delivery network using adjoint senstivity analysis with ieks method

Abstract— The soaring clocking frequency and integration density demand robust and stable power d... more Abstract— The soaring clocking frequency and integration density demand robust and stable power delivery to support tens of millions of transistor switching. In this paper, we consider the problem of mini-mizing the area of wires and decoupling capacitors (decaps) for a power ...

Research paper thumbnail of Virtual Group Learning Effectiveness via eLearning Mediums

Amcis 2005 Proceedings, 2005

Online learning provides the potential for more differentiated, integrated, and open learning env... more Online learning provides the potential for more differentiated, integrated, and open learning environments to solve team project assignments. We argue that although it is feasible to increase information richness via adopting multimedia technologies, the effectiveness to promote interpersonal skills, critical thinking, and cognitive learning processes via virtual group discussion is uncertain. To substantiate the argument, we invited 156 subjects, divided into 46 groups, to resolve decision-and intellective-tasks in text-messaging and audio-conferencing e-learning environments. A pedagogical interpretation of how we can use these two e-learning systems to improve effectiveness for group-based tasks was posited.

Research paper thumbnail of Virtual Factories and Dynamic Core Competency: A Case Study of Advanced Semiconductor Engineering

Due to globalization, advanced information and communication technology has fuelled competition, ... more Due to globalization, advanced information and communication technology has fuelled competition, and building and sustaining of competition advantages are major concerns of companies. Developing dynamic core competency has become a new competition strategy and an important way to help companies remain flexible and able to respond quickly to unpredicted changes in the environment. The development of dynamic core competences requires accumulation of technology and skill over time. In turn, companies can exploit these invisible assets to develop new products and new markets and to out-compete competitors. The Internet could provide value-added service to allow companies to communicate with each other. As such, the Internet-based virtual factory had been implemented to facilitate connections among partners. Taiwan based company Advanced Semiconductor Engineering (ASE), one of the world's largest integrated circuit assembly and testing manufacturers, has constructed its virtual IC factory to strengthen bonds with upstream customers. Customers are able to directly access ASE's information system and thereby receive immediate status reports of their orders or other types of feedback. In this paper, the framework of ASE's virtual IC factory is introduced, and the competitive advantages resulted from this virtual factory are investigated. Implications of ASE's experience are then discussed.

Research paper thumbnail of Identifying attributes for knowledge-based development in dynamic scheduling environments

International Journal of Production Research, 1996