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Ramon Blanco

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Papers by Ramon Blanco

Research paper thumbnail of Dysfunctional Penile Cholinergic Nerves in Diabetic Impotent Men

Research paper thumbnail of Smooth muscle of the corpora cavernosae: Role in penile erection

Research paper thumbnail of Characterization of Trazodone-Associated Priapism: An in Vitro and in Vivo Study

The Journal of Urology, 1987

Research paper thumbnail of Concomitant well-differentiated adenocarcinoma and leiomyosarcoma of the uterus

Archives of pathology & laboratory medicine, 2000

We describe a case of a concomitant well-differentiated endometrial endometrioid adenocarcinoma a... more We describe a case of a concomitant well-differentiated endometrial endometrioid adenocarcinoma and leiomyosarcoma of the uterus in a 66-year-old woman who presented with a 6-month history of vaginal bleeding. The patient underwent total hysterectomy for endometrial carcinoma diagnosed by endometrial biopsy. Gross examination of the specimen revealed an endometrial mass bulging into the endometrial cavity and an underlying well-circumscribed nodule separated from the endometrial mass by a myometrial band. Frozen section performed at the time of the total hysterectomy rendered a diagnosis of malignant mixed-müllerian tumor. Histologic examination of the permanent sections revealed well-differentiated endometrial endometrioid adenocarcinoma clearly separated from a high-grade leiomyosarcoma. Differential diagnosis included malignant mixed-müllerian tumor. However, no admixture of carcinomatous and sarcomatous elements was present. There were no heterologous elements. To the best of ou...

Research paper thumbnail of Systemic lupus erythematosus-associated lymphoproliferative disorder: Report of a case and discussion in light of the literature

Human Pathology, 1997

A case of autoimmune disease-associated lymphadenopathy (ADAL) with histological, immunophenotypi... more A case of autoimmune disease-associated lymphadenopathy (ADAL) with histological, immunophenotypic, Epstein-Barr virus (EBV) in situ hybridization, and genotypic analyses is presented. The patient had a well-documented history of systemic lupus erythematosus (SLE) and was found at autopsy to have massive lymphadenopathy, thymic enlargement, pulmonary nodules, and polyclonal serum dysproteinemia. Histological examination revealed a polymorphous lymphoid infiltrate containing many plasma cells, rare immunoblasts, and a pronounced arborizing vasculature. No foci of necrosis were found and there was no evidence of lymphocyte depletion. The plasma cells were immunophenotypically polyclonal and no EBV mRNA (EBER-1) or gene rearrangements were identified. The unusual gross features, which resembled a malignant lymphoproliferative process, as well as the unusual histological features make this case a notable addition to the spectrum of atypical lymphoproliferative disorders associated with an autoimmune disorder. We conclude that although reminiscent of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD), this case lacks the diagnostic features of AILD, and is, perhaps, best classified as an autoimmune disease-associated lymphadenopathy (ADAL).

Research paper thumbnail of Ultrasonic Mucosectomy of the Gallbladder: A Histological Analysis

HPB Surgery, 1993

The Cavitron Ultrasonic Surgical Aspirator (CUSA) may be used to remove mucosa of organs of the g... more The Cavitron Ultrasonic Surgical Aspirator (CUSA) may be used to remove mucosa of organs of the gastro-intestinal tract. A histological analysis was performed on gallbladders treated with a CUSA-mucosectomy to assess the extent and degree of mucosectomy and to evaluate parietal damage. The histological studies performed on three specimens of chronic cholecystitis revealed a complete mucosectomy except in areas where Rokitansky-Aschof sinuses were present. There was no evidence of parietal damage. The CUSA may be used to remove the mucosa of gallbladders without injury to other layers, and may have a potential application in procedures such as mucosal cholecystectomy.

Research paper thumbnail of Solitary Fibrous Tumor of the Liver

American Journal of Roentgenology, 2000

Research paper thumbnail of Effect of Diabetes Mellitus on Cholinergic Nerves in Human Corpus Cavernosum

The Journal of Urology, 1987

Research paper thumbnail of Dysfunctional Penile Cholinergic Nerves in Diabetic Impotent Men

Research paper thumbnail of Smooth muscle of the corpora cavernosae: Role in penile erection

Research paper thumbnail of Characterization of Trazodone-Associated Priapism: An in Vitro and in Vivo Study

The Journal of Urology, 1987

Research paper thumbnail of Concomitant well-differentiated adenocarcinoma and leiomyosarcoma of the uterus

Archives of pathology & laboratory medicine, 2000

We describe a case of a concomitant well-differentiated endometrial endometrioid adenocarcinoma a... more We describe a case of a concomitant well-differentiated endometrial endometrioid adenocarcinoma and leiomyosarcoma of the uterus in a 66-year-old woman who presented with a 6-month history of vaginal bleeding. The patient underwent total hysterectomy for endometrial carcinoma diagnosed by endometrial biopsy. Gross examination of the specimen revealed an endometrial mass bulging into the endometrial cavity and an underlying well-circumscribed nodule separated from the endometrial mass by a myometrial band. Frozen section performed at the time of the total hysterectomy rendered a diagnosis of malignant mixed-müllerian tumor. Histologic examination of the permanent sections revealed well-differentiated endometrial endometrioid adenocarcinoma clearly separated from a high-grade leiomyosarcoma. Differential diagnosis included malignant mixed-müllerian tumor. However, no admixture of carcinomatous and sarcomatous elements was present. There were no heterologous elements. To the best of ou...

Research paper thumbnail of Systemic lupus erythematosus-associated lymphoproliferative disorder: Report of a case and discussion in light of the literature

Human Pathology, 1997

A case of autoimmune disease-associated lymphadenopathy (ADAL) with histological, immunophenotypi... more A case of autoimmune disease-associated lymphadenopathy (ADAL) with histological, immunophenotypic, Epstein-Barr virus (EBV) in situ hybridization, and genotypic analyses is presented. The patient had a well-documented history of systemic lupus erythematosus (SLE) and was found at autopsy to have massive lymphadenopathy, thymic enlargement, pulmonary nodules, and polyclonal serum dysproteinemia. Histological examination revealed a polymorphous lymphoid infiltrate containing many plasma cells, rare immunoblasts, and a pronounced arborizing vasculature. No foci of necrosis were found and there was no evidence of lymphocyte depletion. The plasma cells were immunophenotypically polyclonal and no EBV mRNA (EBER-1) or gene rearrangements were identified. The unusual gross features, which resembled a malignant lymphoproliferative process, as well as the unusual histological features make this case a notable addition to the spectrum of atypical lymphoproliferative disorders associated with an autoimmune disorder. We conclude that although reminiscent of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD), this case lacks the diagnostic features of AILD, and is, perhaps, best classified as an autoimmune disease-associated lymphadenopathy (ADAL).

Research paper thumbnail of Ultrasonic Mucosectomy of the Gallbladder: A Histological Analysis

HPB Surgery, 1993

The Cavitron Ultrasonic Surgical Aspirator (CUSA) may be used to remove mucosa of organs of the g... more The Cavitron Ultrasonic Surgical Aspirator (CUSA) may be used to remove mucosa of organs of the gastro-intestinal tract. A histological analysis was performed on gallbladders treated with a CUSA-mucosectomy to assess the extent and degree of mucosectomy and to evaluate parietal damage. The histological studies performed on three specimens of chronic cholecystitis revealed a complete mucosectomy except in areas where Rokitansky-Aschof sinuses were present. There was no evidence of parietal damage. The CUSA may be used to remove the mucosa of gallbladders without injury to other layers, and may have a potential application in procedures such as mucosal cholecystectomy.

Research paper thumbnail of Solitary Fibrous Tumor of the Liver

American Journal of Roentgenology, 2000

Research paper thumbnail of Effect of Diabetes Mellitus on Cholinergic Nerves in Human Corpus Cavernosum

The Journal of Urology, 1987

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