Rizka Ruray - Academia.edu (original) (raw)
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Università Cattolica del Sacro Cuore (Catholic University of the Sacred Heart)
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Papers by Rizka Ruray
Open Access Macedonian Journal of Medical Sciences
AV is a global cutaneous disorder that although is benign, can significantly affect the patient’s... more AV is a global cutaneous disorder that although is benign, can significantly affect the patient’s quality of life. The pathognomonic feature of the disease is the emergence of comedones. There are four known pathophysiology of AV, increased sebum production, ductal cornification, colonization of the bacteria P. acnesin the pilosebaceous unit, and inflammation. Furthermore, Vitamin A although already a well-established acne treatment that can affect all four of these factors, here are still limited data regarding the quantitative measurement of vitamin A itself in acne vulgaris cases. This study seeks to review the association between vitamin A levels measured quantitatively using ELISA with the outcome of inflamed lesions and comedones prior and after treatment with Tretinoin 0.025% in patients with mild AV. Our studies found that increased level of vitamin A is associated with significant clinical improvements in both inflamed and non-inflamed AV lesions.
Open Access Macedonian Journal of Medical Sciences, 2021
Background: Nevus lipomatosus cutaneous superficialis (NLCS) of Hoffmann–Zurhelle is a benign idi... more Background: Nevus lipomatosus cutaneous superficialis (NLCS) of Hoffmann–Zurhelle is a benign idiopathic hamartoma. There are two types of NLCS, multiple and solitary. They are found in the abdomen, lower back, buttocks, hips, upper posterior thighs, and pelvis. The diagnosis can be evaluated with a typical histopathological of mature fat cells in the dermis, with 10%–50% of the dermis. Case Report: We reported a case of NLCS with clinical papules and multiple nodules on the buttocks since the age of 6 years with a history of lipoma removal. The dermoscopic examination was conducted to confirm the diagnosis. The histopathological examination showed a dominant sclerotic fibroma with two sessions of biopsy and a few mature fats on the dermis after deeper cuts paraffin block. Cryotherapy with an open spray method is treatment of choice in this patient. Discussion: The appearance of the dermis in NLCS can be normal or an increase in collagen. Interestingly, collagen has sclerosis partia...
Open Access Macedonian Journal of Medical Sciences
AV is a global cutaneous disorder that although is benign, can significantly affect the patient’s... more AV is a global cutaneous disorder that although is benign, can significantly affect the patient’s quality of life. The pathognomonic feature of the disease is the emergence of comedones. There are four known pathophysiology of AV, increased sebum production, ductal cornification, colonization of the bacteria P. acnesin the pilosebaceous unit, and inflammation. Furthermore, Vitamin A although already a well-established acne treatment that can affect all four of these factors, here are still limited data regarding the quantitative measurement of vitamin A itself in acne vulgaris cases. This study seeks to review the association between vitamin A levels measured quantitatively using ELISA with the outcome of inflamed lesions and comedones prior and after treatment with Tretinoin 0.025% in patients with mild AV. Our studies found that increased level of vitamin A is associated with significant clinical improvements in both inflamed and non-inflamed AV lesions.
Open Access Macedonian Journal of Medical Sciences, 2021
Background: Nevus lipomatosus cutaneous superficialis (NLCS) of Hoffmann–Zurhelle is a benign idi... more Background: Nevus lipomatosus cutaneous superficialis (NLCS) of Hoffmann–Zurhelle is a benign idiopathic hamartoma. There are two types of NLCS, multiple and solitary. They are found in the abdomen, lower back, buttocks, hips, upper posterior thighs, and pelvis. The diagnosis can be evaluated with a typical histopathological of mature fat cells in the dermis, with 10%–50% of the dermis. Case Report: We reported a case of NLCS with clinical papules and multiple nodules on the buttocks since the age of 6 years with a history of lipoma removal. The dermoscopic examination was conducted to confirm the diagnosis. The histopathological examination showed a dominant sclerotic fibroma with two sessions of biopsy and a few mature fats on the dermis after deeper cuts paraffin block. Cryotherapy with an open spray method is treatment of choice in this patient. Discussion: The appearance of the dermis in NLCS can be normal or an increase in collagen. Interestingly, collagen has sclerosis partia...