Roberta Giudice - Academia.edu (original) (raw)
Uploads
Papers by Roberta Giudice
Giornale Italiano Di Cardiologia, Apr 1, 2014
Giornale italiano di cardiologia (2006), 2014
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, 2011
The aim of this study was to assess the echocardiographic distribution of regional wall motion ab... more The aim of this study was to assess the echocardiographic distribution of regional wall motion abnormalities (RWMA) in patients with tako-tsubo cardiomyopathy (TTC) compared with anterior ST-elevation myocardial infarction (ant-STEMI). Thirty-seven TTC and 37 ant-STEMI patients underwent standard echocardiographic examination at the time of hospital admission. RWMA and the involvement of the left ventricular territories supplied by each coronary artery according to the American Society of Echocardiography classification were reported. TTC patients showed a lower left ventricular ejection fraction (37.6 ± 5.1 vs. 40.9 ± 3.7%; P = 0.002) and a higher wall motion score index (WMSI; 1.98 ± 0.2 vs. 1.51 ± 0.14; P < 0.001) compared with ant-STEMI patients. No significant differences were observed between groups with regard to detection of RWMA in the territory supplied by the left anterior descending coronary artery (LAD) (37 vs. 37; P = 1). Conversely, in TTC patients, the territories...
Journal of Cardiovascular Echography, 2012
Introduction: We report a case of a 66-year-old man with previous anterior ST-elevated myocardial... more Introduction: We report a case of a 66-year-old man with previous anterior ST-elevated myocardial infarction, treated with primary percutaneous coronary intervention and insertion of drug eluting stent on the left anterior descending coronary artery, and left ventricular (LV) apical aneurysm due to no-reflow. After 2 months follow-up contrast echocardiography allowed to detect giant apical LV thrombosis and to exclude impending LV wall rupture. Anticoagulant oral therapy failed to dissolve the thrombus. Aneurismectomy with left ventricular remodeling and excision of the thrombus was performed successfully and the patient was discharged in good condition. Conclusions: Contrast echocardiography was fundamental in diagnosis of LV thrombus excluding an impending LV wall rupture and to guide treatment.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo, 2011
We report a case of type A intramural aortic hematoma (IMH) occurred in a 78 years old female. Th... more We report a case of type A intramural aortic hematoma (IMH) occurred in a 78 years old female. The clinical scenario (medical history of hypertension, severe substernal chest pain, early diastolic decrescendo murmur as for aortic insufficiency), the laboratory results (no significant troponin level), ECG and transthoracic echocardiography findings (no signs of myocardial ischemia) shifted the initial diagnostic suspicion from acute coronary syndrome to the acute aortic syndrome (AAS) and triggered further imaging tests. Computed tomography revealed an aneurismatic dilatation with thickening of the wall of the ascending aorta without intimal flap. No particular "warning message" for evidence of AAS was sent to the clinician on call. Subsequently, due to the persisting high clinical suspicion transesophageal echocardiography (TEE) was performed. TEE confirmed the aneurysm of the ascending aorta and highlighted an extended and marked aortic wall thickness, consisting with the...
Journal of Cardiovascular Medicine, 2013
Aims To conduct a systematic review of case reports about Tako-tsubo syndrome (TTS) after deliver... more Aims To conduct a systematic review of case reports about Tako-tsubo syndrome (TTS) after delivery in order to assess whether TTS in the postpartum period is a peculiar entity or only a variant form of peripartum cardiomyopathy.
Journal of the American Geriatrics Society, 2012
on behalf of the Tako-tsubo Italian Network Investigators (see Appendix 1) OBJECTIVES: To describ... more on behalf of the Tako-tsubo Italian Network Investigators (see Appendix 1) OBJECTIVES: To describe the clinical characteristics and in-hospital outcomes of older adults with tako-tsubo cardiomyopathy (TTC). DESIGN: Partially retrospective, partially prospective observational study. SETTING: Eleven Italian referral cardiac centers included in the Tako-tsubo Italian Network. PARTICIPANTS: One hundred ninety consecutive individuals with TTC (92.1% female, mean age 66) were divided into three groups according to age (<65, n = 78; 65-74, n = 61; 75, n = 51). MEASUREMENTS: Clinical findings and in-hospital outcomes were evaluated in each group. RESULTS: Participants aged 65 and older had a greater prevalence of hypertension (P = .001) and a lower glomerular filtration rate (P < .001), and those aged 65 to 74 had a greater prevalence of psychiatric disorders (P = .01), STsegment elevation on admission (P = .01) and a cerebrovascular disease (P = .003) than those younger than 65. Despite similar left ventricular ejection fraction (LVEF) on admission (P = .26), the oldest group had a lower LVEF at discharge (P = .03). Inotropic agents were used more frequently in older adults (P = .03). In-hospital composite adverse events (all-cause death, acute heart failure, lifethreatening arrhythmias, stroke, and cardiogenic shock; P = .03) and overall complications (P = .004) were more common in participants aged 75 and older. Overall in-hospital mortality was low (2.8%) but was more prevalent in participants aged 75 and older (6.3%). On multivariate analysis, age of 75 and older (hazard ratio (HR) = 2.45, 95% confidence interval (CI) = 1.28-5.82, P = .04) and LVEF on admission (HR = 0.874, 95% CI = 0.81-0.95, P < .001) were the only independent predictors of inhospital adverse events. CONCLUSION: The clinical profile of participants aged 75 and older with TTC was different from that of those younger than 75 with TTC, and they had a higher in-hospital complication rate. J Am Geriatr Soc 60:93-98, 2012. * Difference between the three age groups according to analysis of variance.
International Journal of Cardiology, 2013
International Journal of Cardiology, 2012
Keywords: tako-tsubo syndrome stress cardiomyopathy transient left ventricular apical ballooning ... more Keywords: tako-tsubo syndrome stress cardiomyopathy transient left ventricular apical ballooning cesarean delivery
JACC: Cardiovascular Imaging, 2014
O B J E C T I V E S To determine clinical and echocardiographic correlates of acute heart failure... more O B J E C T I V E S To determine clinical and echocardiographic correlates of acute heart failure, cardiogenic shock and in-hospital mortality in a large cohort of tako-tsubo cardiomyopathy (TTC) patients.
International Journal of Cardiology, 2011
Objective: Today, aspirin is the cornerstone of antiplatelet therapy in cardiovascular medicine. ... more Objective: Today, aspirin is the cornerstone of antiplatelet therapy in cardiovascular medicine. However the antiplatelet effect of aspirin is not uniform in all patients. Previously published work has demonstrated aspirin resistance in 0.4% to 83.3% of aspirin-treated patients. The aim of this study was to investigate the frequency of aspirin resistance who were taking 100 mg of aspirin and the effect of aspirin resistance on advers clinical events. Methods: 168 patients (115 males and 53 females, mean age 60.1±8.4 years) with stable coronary artery disease who are using aspirin 100 mg/day were included the study. Modified thromboelastogram was used to determine aspirin responsiveness. Aspirin resistance definitions included <50% arachidonic acid induced whole blood trombosit aggregation inhibition by TEG. The patients were followed for an average 464±264 days. The primary outcome were the cardiovascular death due to myocardial infarction (MI), acute coronary syndrome requiring hospitalization and recurrent interventional treatment.
Giornale Italiano Di Cardiologia, Apr 1, 2014
Giornale italiano di cardiologia (2006), 2014
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, 2011
The aim of this study was to assess the echocardiographic distribution of regional wall motion ab... more The aim of this study was to assess the echocardiographic distribution of regional wall motion abnormalities (RWMA) in patients with tako-tsubo cardiomyopathy (TTC) compared with anterior ST-elevation myocardial infarction (ant-STEMI). Thirty-seven TTC and 37 ant-STEMI patients underwent standard echocardiographic examination at the time of hospital admission. RWMA and the involvement of the left ventricular territories supplied by each coronary artery according to the American Society of Echocardiography classification were reported. TTC patients showed a lower left ventricular ejection fraction (37.6 ± 5.1 vs. 40.9 ± 3.7%; P = 0.002) and a higher wall motion score index (WMSI; 1.98 ± 0.2 vs. 1.51 ± 0.14; P < 0.001) compared with ant-STEMI patients. No significant differences were observed between groups with regard to detection of RWMA in the territory supplied by the left anterior descending coronary artery (LAD) (37 vs. 37; P = 1). Conversely, in TTC patients, the territories...
Journal of Cardiovascular Echography, 2012
Introduction: We report a case of a 66-year-old man with previous anterior ST-elevated myocardial... more Introduction: We report a case of a 66-year-old man with previous anterior ST-elevated myocardial infarction, treated with primary percutaneous coronary intervention and insertion of drug eluting stent on the left anterior descending coronary artery, and left ventricular (LV) apical aneurysm due to no-reflow. After 2 months follow-up contrast echocardiography allowed to detect giant apical LV thrombosis and to exclude impending LV wall rupture. Anticoagulant oral therapy failed to dissolve the thrombus. Aneurismectomy with left ventricular remodeling and excision of the thrombus was performed successfully and the patient was discharged in good condition. Conclusions: Contrast echocardiography was fundamental in diagnosis of LV thrombus excluding an impending LV wall rupture and to guide treatment.
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo, 2011
We report a case of type A intramural aortic hematoma (IMH) occurred in a 78 years old female. Th... more We report a case of type A intramural aortic hematoma (IMH) occurred in a 78 years old female. The clinical scenario (medical history of hypertension, severe substernal chest pain, early diastolic decrescendo murmur as for aortic insufficiency), the laboratory results (no significant troponin level), ECG and transthoracic echocardiography findings (no signs of myocardial ischemia) shifted the initial diagnostic suspicion from acute coronary syndrome to the acute aortic syndrome (AAS) and triggered further imaging tests. Computed tomography revealed an aneurismatic dilatation with thickening of the wall of the ascending aorta without intimal flap. No particular "warning message" for evidence of AAS was sent to the clinician on call. Subsequently, due to the persisting high clinical suspicion transesophageal echocardiography (TEE) was performed. TEE confirmed the aneurysm of the ascending aorta and highlighted an extended and marked aortic wall thickness, consisting with the...
Journal of Cardiovascular Medicine, 2013
Aims To conduct a systematic review of case reports about Tako-tsubo syndrome (TTS) after deliver... more Aims To conduct a systematic review of case reports about Tako-tsubo syndrome (TTS) after delivery in order to assess whether TTS in the postpartum period is a peculiar entity or only a variant form of peripartum cardiomyopathy.
Journal of the American Geriatrics Society, 2012
on behalf of the Tako-tsubo Italian Network Investigators (see Appendix 1) OBJECTIVES: To describ... more on behalf of the Tako-tsubo Italian Network Investigators (see Appendix 1) OBJECTIVES: To describe the clinical characteristics and in-hospital outcomes of older adults with tako-tsubo cardiomyopathy (TTC). DESIGN: Partially retrospective, partially prospective observational study. SETTING: Eleven Italian referral cardiac centers included in the Tako-tsubo Italian Network. PARTICIPANTS: One hundred ninety consecutive individuals with TTC (92.1% female, mean age 66) were divided into three groups according to age (<65, n = 78; 65-74, n = 61; 75, n = 51). MEASUREMENTS: Clinical findings and in-hospital outcomes were evaluated in each group. RESULTS: Participants aged 65 and older had a greater prevalence of hypertension (P = .001) and a lower glomerular filtration rate (P < .001), and those aged 65 to 74 had a greater prevalence of psychiatric disorders (P = .01), STsegment elevation on admission (P = .01) and a cerebrovascular disease (P = .003) than those younger than 65. Despite similar left ventricular ejection fraction (LVEF) on admission (P = .26), the oldest group had a lower LVEF at discharge (P = .03). Inotropic agents were used more frequently in older adults (P = .03). In-hospital composite adverse events (all-cause death, acute heart failure, lifethreatening arrhythmias, stroke, and cardiogenic shock; P = .03) and overall complications (P = .004) were more common in participants aged 75 and older. Overall in-hospital mortality was low (2.8%) but was more prevalent in participants aged 75 and older (6.3%). On multivariate analysis, age of 75 and older (hazard ratio (HR) = 2.45, 95% confidence interval (CI) = 1.28-5.82, P = .04) and LVEF on admission (HR = 0.874, 95% CI = 0.81-0.95, P < .001) were the only independent predictors of inhospital adverse events. CONCLUSION: The clinical profile of participants aged 75 and older with TTC was different from that of those younger than 75 with TTC, and they had a higher in-hospital complication rate. J Am Geriatr Soc 60:93-98, 2012. * Difference between the three age groups according to analysis of variance.
International Journal of Cardiology, 2013
International Journal of Cardiology, 2012
Keywords: tako-tsubo syndrome stress cardiomyopathy transient left ventricular apical ballooning ... more Keywords: tako-tsubo syndrome stress cardiomyopathy transient left ventricular apical ballooning cesarean delivery
JACC: Cardiovascular Imaging, 2014
O B J E C T I V E S To determine clinical and echocardiographic correlates of acute heart failure... more O B J E C T I V E S To determine clinical and echocardiographic correlates of acute heart failure, cardiogenic shock and in-hospital mortality in a large cohort of tako-tsubo cardiomyopathy (TTC) patients.
International Journal of Cardiology, 2011
Objective: Today, aspirin is the cornerstone of antiplatelet therapy in cardiovascular medicine. ... more Objective: Today, aspirin is the cornerstone of antiplatelet therapy in cardiovascular medicine. However the antiplatelet effect of aspirin is not uniform in all patients. Previously published work has demonstrated aspirin resistance in 0.4% to 83.3% of aspirin-treated patients. The aim of this study was to investigate the frequency of aspirin resistance who were taking 100 mg of aspirin and the effect of aspirin resistance on advers clinical events. Methods: 168 patients (115 males and 53 females, mean age 60.1±8.4 years) with stable coronary artery disease who are using aspirin 100 mg/day were included the study. Modified thromboelastogram was used to determine aspirin responsiveness. Aspirin resistance definitions included <50% arachidonic acid induced whole blood trombosit aggregation inhibition by TEG. The patients were followed for an average 464±264 days. The primary outcome were the cardiovascular death due to myocardial infarction (MI), acute coronary syndrome requiring hospitalization and recurrent interventional treatment.