Sameer Qureshi - Academia.edu (original) (raw)

Papers by Sameer Qureshi

PAFMJ, 2021

Methodology: Proforma was designed to collect data for the study. Patients and/or attendants were... more Methodology: Proforma was designed to collect data for the study. Patients and/or attendants were asked questions regarding PPD ingestion reason, evidence of poison ingestion, symptoms, color, and route and time interval to reach hospital. All of the collected were entered in SPSS and analyzed using SPSS version 21. Descriptive statistics in terms of mean ± standard deviation or frequencies with percentages were computed to summarize the collected data as appropriate. Result: Total 44 patients came to emergency department with diagnosis of black stone (kalapathar poisoning) as evident by patient or by attendant. Out of them 29 patients were female (65.9%). Majority of patients 35 (79.54%) were age between 15-30 years Most of the patients 41 (93.18%) took more than 2 hours to reach hospital patients were of age between 41-50 years. Forty-two (95.5%) out of 44 ingested PPD with an intention to suicide while only 2 (4.5%) patients ingested PPD accidentally. Forty patients (90%) had severe tongue and neck swelling and underwent emergency tracheostomy while on the other hand, only 4 patients (9.09%) presented with minor tongue swelling and cervicofacial edema impending stridor clinically. Out of these 4 patients, 2 further underwent emergency tracheostomy. Conclusion: Paraphenylenediamine poisoning is commonly used in Pakistan for suicidal purpose especially in females as its easily available and cheap. All of the patients need Emergency tracheostomy due to angioneurotic edema leads to asphyxia. Therefore, we need to spread awareness so that its availability should be banned and Psychiatrists should do counseling of such patients for their mental health.

Pakistan Journal of Medical and Health Sciences, 2021

Objective: To determine frequency of complication of modified radical neck dissection in patients... more Objective: To determine frequency of complication of modified radical neck dissection in patients at a tertiary care hospital Karachi, Pakistan Material and Methods: Study design: This is a cross sectional section study, conducted at Department of ENT, for Six months from January 1, 2019 to July 1, 2019. All the patients who fulfilled the inclusion criteria and visited to department of ENT, were included in the study after taking informed consent. Patients were discharged by 48-72 hours postoperatively. Patients were assessed daily till the time of discharge for occurrence of nerve complication, wound complications and vascular complications. Data was entered and analyzed by SPSS 21 software. Mean, Frequency and percentage were given for continuous and discreet data respectively. Chi squire test was applied to detect significance. P value of < o.o5 was taken as significant. Results: Mean ± SD of age was 40.31±9.54 with C.I (38.62.......41.99) years. Out of 126 patients 84 (67%) w...

Global journal for research analysis, 2018

This prospective consecutive case series was done to evaluate indications, technical pitfalls and... more This prospective consecutive case series was done to evaluate indications, technical pitfalls and functional outcome of elastic stable intramedullary nailing of displaced midclavicular fractures in 34 high demand individuals. Constant score and radiographs were evaluated after 1 and 6 weeks, 3 months and 6 months in 34 patients. Mean age was 28 years. The average follow-up was 12 months. Mean operation time was 42 minutes. Open reduction through an additional small incision was necessary for 7 fractures. Mean hospital stay was 1.2 days. Secondary fracture displacement was observed in 1 patient. The Constant score averaged 81 after 1 week, 96 after 6 weeks and 98 after 6 months. Compared to the contralateral side, average shortening of the clavicle was 1.7 mm. Overall, elastic stable intramedullary nailing provided good restoration of the length of the clavicle and allowed immediate active mobilisation with early return to normal activity. Functional results were excellent.

1 Department of E.N.T, Jinnah Sindh Medical University/JPMC, Karachi, Pakistan 2 Department of E.... more 1 Department of E.N.T, Jinnah Sindh Medical University/JPMC, Karachi, Pakistan 2 Department of E.N.T, Civil Hospital, Karachi, Pakistan 3 Department of E.N.T, Pakistan Institute of Medical Sciences, Islamabad, Pakistan 4 Department of E.N.T, Dr. Fasih’s ENT Hospital, Karachi, Pakistan 5 Department of E.N.T, Mayo Hospital, Lahore, Pakistan 6 Department of E.N.T, Abbasi Shaheed Hospital, Karachi, Pakistan 7 Khyber Teaching Hospital,Pakistan 8 Department of E.N.T Services Hospital, Lahore, Pakistan 9 Department of Medical Affairs, Abbott Laboratories, Karachi, Pakistan

Pakistan Heart Journal, 2021

Objective: This study was done to determine the association between lipid levels and diabetic Ind... more Objective: This study was done to determine the association between lipid levels and diabetic Indices in confirm patients of myocardial infarction with versus without diabetes mellitus type II. Methodology: Two hundred acute myocardial infarction having ST-segment elevation patients with diabetes mellitus type II and without diabetes mellitus type II were enrolled. Lipid levels and diabetic indices were measured, and the correlations among them were analyzed. Results: Positive correlations were found between triglycerides and fasting blood sugar, low density lipoprotein and Insulin when compared among myocardial infarction patients. Comparison among myocardial infarction patients with diabetes mellitus type II and without diabetes mellitus type II, negative correlations were found between triglycerides and glycosylated hemoglobin (HbA1C), low density lipoprotein and glycosylated hemoglobin, glycosylated hemoglobin and Insulin. Conclusion: Correlations between lipid levels and diabet...

Pakistan Heart Journal, 2018

Objective: To evaluate the levels of pro-inflammatory cytokines Interleukin-6,Tumor necrosis fact... more Objective: To evaluate the levels of pro-inflammatory cytokines Interleukin-6,Tumor necrosis factor-α before and after angioplasty in patients of myocardialinfarction with and without diabetes mellitus type II. Methodology: This cross sectional study included patients between the age of 40and 60years presented to National Institute of Cardiovascular diseases, Karachi .Patients were divided into 2 groups. First group comprised of myocardialinfarction patients, second group included patients with myocardial infarctionand diabetes mellitus type 2. Serum Interleukin-6, Tumor Necrosis Factor-α,serum triglycerides, cholesterol, LDL cholesterol HDL cholesterol, FBS, HbA1Cand Insulin concentrations were determined. P value was determined byStudents t test. Chi Square test was applied to gender and smoking. Results: We included 200 patients. The patients were divided into 2 groups andeach group comprised of 100 subjects. First group comprised of MyocardialInfarction patients, second group My...

Journal of the Dow University of Health Sciences, 2014

Background: Patient satisfaction is an important parameter of evaluating health care services fro... more Background: Patient satisfaction is an important parameter of evaluating health care services from a patient’sperspective. In terms of “people centered healthcare”, it has gained importance over last few decades; but theconcept is generally neglected in quality assessment of healthcare setups by developing countries like Pakistan.We aimed to assess the level of satisfaction among outpatients receiving healthcare services at the surgicaloutpatient department, Civil Hospital Karachi, Pakistan; and identify the aspects of healthcare service delivery’squality associated with patient’s dissatisfaction. Methods: A cross sectional study was conducted at the surgical outpatient department , Civil Hospital Karachi(CHK). Information relating to patient’s evaluation of health care service delivery, and level of satisfactionwere collected through post consultation survey of 454 patients attending the OPD from 28th February, 2014to 30th April, 2014. Results: We found that almost three quarters (...

Correspondence: Dr. Hurtamina Khan 1* Depar tment of ENT/ Head and Neck Surgery Jinnah Postgradua... more Correspondence: Dr. Hurtamina Khan 1* Depar tment of ENT/ Head and Neck Surgery Jinnah Postgraduate Medical Centre Jinnah Sindh Medical University Karachi E mail: drhurtamina@hotmail.com INTRODUCTION: Parapharyngeal space tumors are rare among the head and neck neoplasms. They are among the most challenging neoplasms in terms of diagnosis and management. The parapharyngeal region is a potential space where a diverse group of inflammatory diseases may co exit that involve the nasopharynx and tonsillar regions, including the parotid glands. A broad range of benign and malignant invasive lesions tend to occur in this anatomic area. Primary A B S T R A C T

Journal of Religion and Health, 2021

Distress causes psychophysiological alterations that affect autonomic function. The current study... more Distress causes psychophysiological alterations that affect autonomic function. The current study explores psychophysiological modulation in diabetic distress in response to Surah Al-Rehman recitation. A single-group experimental study with before and after intervention assessments was conducted during April 2018 to February 2019 in which participants (n = 10) listened to Surah Al-Rehman recitation. Blood pressure, blood glucose, cortisol, ECG and EEG were recorded before and after recitation. Significant reduction in systolic blood pressure, increase in low frequency and absolute alpha power at Fp2 were observed. Heartbeat evoked potentials (HEP) were also significantly modulated at Fp1, Fp2 and F4. These findings suggest that Surah Al-Rehman modulated baroreflex activity thereby reducing sympathetic activity and improved heart brain coherence as reflected by HEP.

Pakistan journal of pharmaceutical sciences, 2018

To assess levels of Interleukin-1 β and CRP, in Diabetic and Non-diabetic Myocardial Infarction p... more To assess levels of Interleukin-1 β and CRP, in Diabetic and Non-diabetic Myocardial Infarction patients, prior to and post angioplasty. 200 patients were recruited in the study. MI patients between the age of 40 and 60 years. Patients came to NICVD with complaints of chest pain, positive Troponin T test and ECG was the confirmatory test for MI. They were divided into 2 groups 100 patients each. First group comprised of MI patients without DMT-II and second group comprised of MI patients with DMT-II. Serum triglycerides, cholesterol, LDL and HDL, FBS, by enzymatic kits, Insulin by RIA. HbA1C, Interleukin-1 β and CRP by ELIZA. Interleukin1β and CRP were significantly higher (P<0.001) in patients at the time of the infarction, prior to angioplasty as compared post angioplasty levels in both groups, which indicate their importance in development of ischemia and MI. FBS and Insulin were significantly higher (P<0.001), while HDL and HbA1C were significantly lower (P<0.001) in MI...

Head & neck, Jul 29, 2017

Head and neck Merkel cell carcinoma (MCC) is commonly treated with surgery and adjuvant radiother... more Head and neck Merkel cell carcinoma (MCC) is commonly treated with surgery and adjuvant radiotherapy (RT) for high-risk features. The optimal radiation dose is unknown. One thousand six hundred twenty-five eligible patients with head and neck MCC were identified in the National Cancer Data Base (NCDB). Radiation dose was divided into 3 groups: 30 to <50 Gray (Gy), 50-55 Gy, and >55-70 Gy. Cox regression was used to compare overall survival (OS) between groups, accounting for age, sex, stage, surgery type, margin status, comorbidities, and use of chemotherapy. With a median follow-up of 33.5 months, 3-year OS was 48.9%, 70.3%, and 58.7% for 30 to <50 Gy, 50-55 Gy, and >55-70 Gy, respectively (P < .001). Compared to 50-55 Gy, doses between 30 to <50 Gy (adjusted hazard ratio [HR] 1.53; 95% confidence interval [CI] 1.17-1.99; P = .002) and >55-70 Gy (adjusted HR 1.21; 95% CI 1.0-1.46; P = .06) were associated with worse survival. Adjuvant radiation doses within 50-...

European Journal of Dentistry, 2016

ABSTRACTTooth wear is a process that is usually a result of tooth to tooth and/or tooth and resto... more ABSTRACTTooth wear is a process that is usually a result of tooth to tooth and/or tooth and restoration contact. The process of wear essentially becomes accelerated by the introduction of restorations inside the oral cavity, especially in case of opposing ceramic restorations. The newest materials have vastly contributed toward the interest in esthetic dental restorations and have been extensively studied in laboratories. However, despite the recent technological advancements, there has not been a valid in vivo method of evaluation involving clinical wear caused due to ceramics upon restored teeth and natural dentition. The aim of this paper is to review the latest advancements in all-ceramic materials, and their effect on the wear of opposing dentition. The descriptive review has been written after a thorough MEDLINE/PubMed search by the authors. It is imperative that clinicians are aware of recent advancements and that they should always consider the type of ceramic restorative ma...

PLOS ONE, 2016

Background Several developing countries like Pakistan step into Sustainable Development Goals per... more Background Several developing countries like Pakistan step into Sustainable Development Goals period with crucial maternal and child health needs that need to be addressed for improving health outcomes among people. We aim to explore existent socioeconomic disparities in use of family planning methods (FPM) among Pakistani women, and compare any such inequalities between the years 2006 and 2013.

Science (New York, N.Y.), Jan 17, 2015

Outbreaks of Middle East respiratory syndrome (MERS) raise questions about the prevalence and evo... more Outbreaks of Middle East respiratory syndrome (MERS) raise questions about the prevalence and evolution of the MERS coronavirus (CoV) in its animal reservoir. Our surveillance in Saudi Arabia in 2014 and 2015 showed that viruses of the MERS-CoV species and a human CoV 229E-related lineage co-circulated at high prevalence, with frequent co-infections in the upper respiratory tract of dromedary camels. Including a betacoronavirus 1 species, we found that dromedary camels share three CoV species with humans. Several MERS-CoV lineages were present in camels, including a recombinant lineage that has been dominant since December 2014 and that subsequently led to the human outbreaks in 2015. Camels therefore serve as an important reservoir for the maintenance and diversification of the MERS-CoVs and are the source of human infections with this virus.

Journal of Dow University of Health Sciences, Jan 12, 2014

Well, not really. But the above title certainly directs the reader towards the actual adage: "onc... more Well, not really. But the above title certainly directs the reader towards the actual adage: "once a thief, always a thief". Does this make both the words (plagiarist and thief) synonymous? In a way, yes, it does. Derived from the Latin words 'plagiare' (to kidnap) 1 and 'plagiatum' (stealing people) 2 , the word 'plagiarism' is defined as:

Journal of Clinical Case Reports, 2015

Ependymomas constitute 4-6% of primary central nervous system tumors. Spinal ependymomas are most... more Ependymomas constitute 4-6% of primary central nervous system tumors. Spinal ependymomas are most frequently found in intramedullary region but few cases of intradural extramedullary ependymoma have also been reported. We report a 24-year-old male patient with a suspected case of intradural extramedullary ependymoma. Magnetic resonance images of the lumbar spine depicted an intradural mass from L1-L4 level. The spinal lesion was isointense on T1-weighted images and hyperintense on T2-weighted images, relative to the spinal cord. Laminectomy L1-L4 with gross-total excision was performed. Histopathological examination was inconclusive but suggested the possibility of ependymoma. Neurological recovery was initially observed but after few months symptoms worsened.

International Journal of Health System and Disaster Management, 2015

Objectives: Polluted biomass fuel important contributor for low birth weight (LBW). Exposure to b... more Objectives: Polluted biomass fuel important contributor for low birth weight (LBW). Exposure to biomass fuel during pregnancy lead to LBW, the objective of this study was to determine the association of exposure to biomass fuel and LBW. Methods: In total, 10,023 ever married women were interviewed reported 41,094 births for last 5 years from Pakistan Demographic Health Survey 2006–07. Logistic regression models were used to assess the association between biomass exposure and birth weight after adjusting for demographic, maternal, and child characteristics. Odds ratios (ORs), 95% confidence interval (CI) and P value were calculated. Results: The proportion of LBW was 35.4% ( n = 1777) in common high polluted biomass fuel (wood), 36.3% ( n = 282) in less common high polluted biomass fuel (electricity, cylinder gas, and biogas) and 29.5% ( n = 805) in common low polluted biomass fuel (natural gas). Infants born to common high polluted biomass fuel (wood) users were 28% more likely to have LBW (OR: 1.28, 95% CI: 1.02–1.61, P = 0.03) compared with infants born to common low polluted biomass fuel (natural gas) users while significant positive association of less common high polluted biomass fuel with LBW (OR: 1.41, 95% CI: 1.07–1.84, P value 0.01) after adjusting for potential confounders. Conclusion: Biomass fuel exposure during pregnancy was significantly associated with LBW of child. There is need for reduce the exposure of polluted biomass fuel and replace with low biomass fuel to reduced burden of LBW.

Indian Journal of Otology, 2015

Objective: Chronic suppurative otitis media (CSOM) can lead to dreadful and fatal complications. ... more Objective: Chronic suppurative otitis media (CSOM) can lead to dreadful and fatal complications. Objective of my study is an assessment of factors leading to the development of CSOM complications in different age groups and which age group is more prone to the development of complications. And to find out most frequent complication occurring in the target population. Introduction: CSOM is a long standing infection of a part or whole of the middle ear cleft characterized by ear discharge and a permanent perforation. It affects both sexes and all age groups. Pathways of spread of infection: Direct bone erosion, venous thrombophlebitis, preformed pathways. Classification of complications: Intracranial - Mastoiditis, facial paralysis, labrynthitis, petrositis. Extracranial - Meningitis, extradural abscess, subdural abscess, brain abscess, lateral sinus thrombophlebitis, otitic hydrocephalus. Development of complications depends upon; organism′s virulence, poor resistance of the patient, systemic disease, resistance to antibiotics, poor socioeconomic status, lack of awareness about healthcare, lack of availability of trained specialist. Materials and Methods: A descriptive cross-sectional study was carried out from 2008 to 2013 in ENT Head and Neck Surgery Department, Jinnah Postgraduate Medical Centre, Karachi. Record of 65 patients was selected through nonprobability convenient sampling; sample was divided into two groups according to age Group A 10-18 years and Group B 18-45 years. Data were analyzed on SPSS software; Chi-square test was used and P < 0.05 was considered significant with confidence interval taken as 95%. Results: Population means age was found to be 18.28. Population sex dominant was male 63.1%. Mean duration of complaints is 1.69. There are strong associations between duration of complaints and family income (P = 0.05), and also between age of patient and diagnosed complication (P = 0.00). Conclusions: Most of the patients were of poor socioeconomic background with disease negligence, delayed treatment, poor access to health facilities and improper use of antibiotics. Mostly low age group patients develop complications.

Rawal Medical Journal

Objective: To generate national level statistics to calculate the disease burden and to implement... more Objective: To generate national level statistics to calculate the disease burden and to implement awareness and screening programs for breast cancer. Methodology: All breast biopsies received at the Dow Diagnostic Research and Reference laboratory (DDRRL) during 2008-2012 were included in the analyze the spectrum with implementation of latest intrinsic molecular subtyping. Results: Out of 2740 cases, 1493 (54.50%) were diagnosed as benign and 1247 (45.40%) as malignant lesions. Most frequent lesion in male was gynecomastia. However, in females, most common benign lesion was fibroadenoma with a frequency of 745 (27.91%), while invasive ductal carcinoma II was the most common malignant lesions observed in 584 (21.88%) cases. Mean age of patients with benign lesion was 30 years and malignant lesion was 45 years. Selected cases (n=460) were stained for ER, PgR and Her-2 expression. Of these, ER expression was found in 208 (44.30%) biopsies, PgR was found to be positive in 183 (38.90%) a...