Shirley Taniguchi - Academia.edu (original) (raw)

Papers by Shirley Taniguchi

Anais de Farmacia e Quimica, 1987

Objective: To check the occurrence of extrapyramidal side effects in patients receiving neurolept... more Objective: To check the occurrence of extrapyramidal side effects in patients receiving neuroleptic drugs, how these effects are treated, and to observe the occurrence of hallucinations caused by treatment of extrapyramidal symptoms. Methods: The present study analyzed medical records and interviewed 39 schizophrenic patients being treated in a public primary care clinic located in the southern part of the city of São Paulo, who had previously agreed to participate in the project. results: Among 39 patients studied, 85% presented extrapyramidal symptoms. Of these, 69.7% were treated for the side effects, 73.9% were treated with biperiden and 26.09% had their neuroleptic drug reduced. Out of those patients treated with biperiden, 70.5% had side effects, such as hallucination and delusion, blurred vision, somnolence and verbal memory deficit. conclusions: The majority of patients (85%) undergoing treatment with neuroleptic drugs developed motor side effects. When these extrapyramidal ...

Einstein (São Paulo), 2008

Objetivo: Identificar a ocorrencia de efeitos extrapiramidais (EPS) com o uso de neurolepticos, e... more Objetivo: Identificar a ocorrencia de efeitos extrapiramidais (EPS) com o uso de neurolepticos, em pacientes esquizofrenicos, bem como verificar o possivel aparecimento de alucinacao secundaria ao tratamento dos EPS. Metodos: Trinta e nove pacientes que estiveram em tratamento com neurolepticos em uma instituicao publica de atencao primaria em saude mental, localizada na regiao sul da cidade de Sao Paulo, tiveram seus dados coletados do prontuario e participacao por meio de entrevistas apos concordarem, voluntariamente, em fazer parte da pesquisa. Resultados: Dos 39 pacientes esquizofrenicos em tratamento com neurolepticos analisados, 85% apresentaram EPS, enquanto 69,7% receberam tratamento para estes efeitos colaterais de movimento. Foram tratados com biperideno 73,91% dos pacientes, enquanto 29,06% tiveram reducao da dose do neuroleptico. Dos pacientes que receberam biperideno, 70,50% apresentaram alucinacao/delirio, visao embacada, sonolencia ou deficit de memoria verbal. Conclu...

General pharmacology, 1995

1. The effectiveness of the inclusion product of piroxicam with beta-cyclodextrin was compared to... more 1. The effectiveness of the inclusion product of piroxicam with beta-cyclodextrin was compared to that of free piroxicam on inflammatory reactions by using three experimental inflammatory models in rats. 2. The inclusion compound showed anti-inflammatory effects similar to those of simple piroxicam on granuloma tissue formation and arthritis induced by complete Freund adjuvant. 3. In carrageenin-induced pleurisy, the piroxicam beta-cyclodextrin reduced leukocyte mobilization more intensely than non-complexed piroxicam. 4. These results suggest that beta-cyclodextrin is a useful tool for improving the efficacy of piroxicam.

Phytotherapy Research, 1997

Antiinflammatory activities of aqueous and saponin extracts and ecdysterone obtained from Pfaffia... more Antiinflammatory activities of aqueous and saponin extracts and ecdysterone obtained from Pfaffia iresinoides (Sprengel) were studied by using three experimental inflammatory models in rats. The saponin extract (25 and 50 mg/kg, p.o.) reduced the leukocyte migration, particularly of mononuclear cells in the carrageenin-induced pleurisy. It also inhibited the granuloma tissue formation following cotton pellet implantation and the complete Freund's adjuvant-induced arthritis. The aqueous extract, in the same conditions, was effective on both carrageenin-induced pleurisy and complete Freund's adjuvant arthritis. However, it did not alter the granuloma formation. The ecdysterone (5 mg/kg, p.o.), isolated from P. iresinoides, showed no effect on these inflammatory processes.

apps.einstein.br

objective: To check the occurrence of extrapyramidal side effects in patients receiving neurolept... more objective: To check the occurrence of extrapyramidal side effects in patients receiving neuroleptic drugs, how these effects are treated, and to observe the occurrence of hallucinations caused by treatment of extrapyramidal symptoms. Methods: The present study analyzed ...

General Pharmacology: The Vascular System, 1995

Ahstraet-l. The effectiveness of the inclusion product of piroxicam with fl-cyclodextrin was comp... more Ahstraet-l. The effectiveness of the inclusion product of piroxicam with fl-cyclodextrin was compared to that of free piroxicam on inflammatory reactions by using three experimental inflammatory models in rats. 2. The inclusion compound showed anti-inflammatory effects similar to those of simple piroxicam on granuloma tissue formation and arthritis induced by complete Freund adjuvant, 3. In carrageenin-induced pleurisy, the piroxieam/~-cyclodextrin reduced leukocyte mobilization more intensely than non-complexed piroxicam. 4. These results suggest that fl-cyclodextrin is a useful tool for improving the el~cacy of piroxicam.

To check the occurrence of extrapyramidal side effects in patients receiving neuroleptic drugs, h... more To check the occurrence of extrapyramidal side effects in patients receiving neuroleptic drugs, how these effects are treated, and to observe the occurrence of hallucinations caused by treatment of extrapyramidal symptoms. Methods: The present study analyzed medical records and interviewed 39 schizophrenic patients being treated in a public primary care clinic located in the southern part of the city of São Paulo, who had previously agreed to participate in the project. results: Among 39 patients studied, 85% presented extrapyramidal symptoms. Of these, 69.7% were treated for the side effects, 73.9% were treated with biperiden and 26.09% had their neuroleptic drug reduced. Out of those patients treated with biperiden, 70.5% had side effects, such as hallucination and delusion, blurred vision, somnolence and verbal memory deficit. conclusions: The majority of patients (85%) undergoing treatment with neuroleptic drugs developed motor side effects. When these extrapyramidal symptoms were treated with central action anticholinergic drugs (biperiden), hallucination and/or delusion occurred in 52.94% of patients -probably because of increased dopaminergic activity as a consequence of cholinergic activity reduction caused by biperiden in the mesocortical and mesolimbic pathways.