Sonali Deshmukh - Academia.edu (original) (raw)

Papers by Sonali Deshmukh

Research paper thumbnail of Cervicomental angle changes observed after mandibular advancement surgery – A systematic review

APOS Trends in Orthodontics, 2021

Purpose: In adults, correction of such a jaw base relation is done by bilateral sagittal split os... more Purpose: In adults, correction of such a jaw base relation is done by bilateral sagittal split osteotomy and mandibular advancement which often causes change in the cervicomental angle that might not be within the acceptable and aesthetic range. The objective of this systematic review was to evaluate the changes observed in cervicomental angle after mandibular advancement surgery. Data Sources: Based on the available data, we conducted an electronic database PubMed search, based on the search of published data from 1994 to 2017, six strategies were designed using two keywords, and four articles were shortlisted for systematic review. Study Eligibility Criteria: Studies that provide information on cervicomental angle changes after mandibular advancement surgery, published from 1994 to 2017. Results: The search yielded 168 articles, of which four were included based on the selection criteria. These articles described that the cervicomental angle observed after mandibular advancement s...

Research paper thumbnail of Mean values of Beta Angle and YEN Angle in Maratha ethnic population and their reliability on select local population: A cephalometric observational study

International journal of scientific research, 2017

Objective: Different ethnic groups present variations in the various cephalometric analyses that ... more Objective: Different ethnic groups present variations in the various cephalometric analyses that are performed to determine the sagittal relation. This study is aimed at establishing the norms for Beta angle and Yen angle in Maratha population and to evaluate their reliability in sagittal malocclusions from amongst select local population. Materials and Method: A total of 120 samples were divided into three categories. 60 samples of Class I normal occlusion (30 males and 30 females) were used to establish the norms. 60 samples with skeletal Class II and Class III relation were used for checking the reliability of the established norms. Lateral cephalogram of all the samples was procured and tracings were done to calculate ANB Angle, Wits appraisal, McNamara differential, Beta angle and Yen angle. Oneway ANOVA was done to determine the means of Beta and YEN angle in Maratha population. Results: The Maratha population norms for Beta angle is 31.50 +/- 2.70 and for YEN angle is 122.20 ...

Research paper thumbnail of Evaluation of Changes in Condylar Cartilage Thickness Using MRI and Ultrasound Imaging in Patients Treated by Mandibular Advancement With Myofunctional Appliance: An In-Vivo Pilot Study

Cureus, 2021

The changes occurring due to growth modulation of the condylar cartilage act as an important mech... more The changes occurring due to growth modulation of the condylar cartilage act as an important mechanism for mandibular advancement using myofunctional appliance therapy. So this study aims to evaluate the condylar cartilage thickness by using MRI and USG in patients undergoing myofunctional appliance therapy for mandibular advancement with the null hypothesis being that there are no changes seen in the thickness of condylar cartilage in growing children. Materials and methods A prospective evaluation of samples having skeletal Class-II malocclusion ranging between cervical vertebral maturation index (CVMI) stage II and III, requiring twin block functional therapy was performed. Ten patients were selected randomly who underwent MRI and USG in the open and close positions for the evaluation of condylar cartilage thickness and the dimensional changes in the width of the right and left condyle in mm at T0 and T1. Result There was no statistically significant difference between the values interpreted by MRI or USG imaging when compared at T0 and T1 and in the open and closed mouth on the left and right sides. At T0, the mean thickness noted was 0.49 mm and 0.48 mm during opening and closing on the left side and 0.52 mm in both positions on the right side. At T1, the mean thickness noted was 0.8 and 0.79mm during opening and closing on the left side, whereas it was 0.81 mm in both positions on the right side. Conclusion The condylar cartilage thickness increases significantly after twin block therapy suggestive of mandibular growth in skeletal class II malocclusion. It can be inferred that both MRI and USG carry equal diagnostic interpretation, as there was no statistically significant difference between the two imaging modalities.

Research paper thumbnail of Establishment of norms for crown angulation and inclination among Maratha population: Cross-Sectional Study

Objectives: Selection of an appropriate bracket prescription for any particular individual or pop... more Objectives: Selection of an appropriate bracket prescription for any particular individual or population facilitates idealistic and realistic goals for different esthetic around the world. As Caucasian norms show a great degree of variation when applied to different populations, it becomes necessary to establish the norms for every ethnic group. The present study was designed to derive norms of crown angulation and inclination for the Maratha ethnic population, which would be compared with Caucasian norms. Materials and Method: The sample consisted of 100 adult subjects (50 males and 50 females) of Maratha ethnic origin with traced back to two generations, age group of 18 years and above. Acceptable and straight profiles; Class I molar relation on both sides; with normal overjet and overbite; well aligned arches. Orthodontic Torque Angulation Device (TAD) was used to measure the crown angulation and inclination. Comparison of these values with those established by Andrews is done us...

Research paper thumbnail of Impact of the pandemic on cancer care: Lessons learnt from a rural cancer center in the first 3 months

Journal of Surgical Oncology, 2020

The COVID‐19 outbreak and the subsequent declaration of pandemic was an unprecedented event, whic... more The COVID‐19 outbreak and the subsequent declaration of pandemic was an unprecedented event, which created different complex situations for treatment of cancer patients. A critical assessment of the response to this calamity and its impact on healthcare workers (HCWs) and patient care in a dedicated cancer hospital is analyzed.

Research paper thumbnail of Clinical use of orthodontic mini-implants for intrusion and retraction: a systematic review

Australasian Orthodontic Journal, 2021

Background Bimaxillary dental protrusion is common in many ethnic groups and is generally treated... more Background Bimaxillary dental protrusion is common in many ethnic groups and is generally treated by the extraction of all first premolars. However, temporary anchorage devices (TADs) are currently gaining popularity and most studies have focused on anchorage loss, treatment duration, mini-implant success and failure rates, pain, discomfort and root resorption. Few studies have focused on the clinical effectiveness of implants for the intrusion and retraction of anterior teeth. Objectives To assess the clinical use of orthodontic mini-implants for the intrusion and retraction of anterior teeth. Methods A systematic review of articles selected from PUBMED and Google Scholar was carried out to determine the clinical use of orthodontic mini-implants for anterior tooth intrusion and retraction. Additional studies were hand searched to identify and include clinical trials, prospective and retrospective studies, while excluding finite element method (FEM) studies and case reports. A total...

Research paper thumbnail of Crystal structure of XCC3289 from Xanthomonas campestris: homology with the N-terminal substrate-binding domain of Lon peptidase

Acta Crystallographica Section F Structural Biology Communications, 2020

LonA peptidase is a major component of the protein quality-control mechanism in both prokaryotes ... more LonA peptidase is a major component of the protein quality-control mechanism in both prokaryotes and the organelles of eukaryotes. Proteins homologous to the N-terminal domain of LonA peptidase, but lacking its other domains, are conserved in several phyla of prokaryotes, including the Xanthomonadales order. However, the function of these homologous proteins (LonNTD-like proteins) is not known. Here, the crystal structure of the LonNTD-like protein from Xanthomonas campestris (XCC3289; UniProt Q8P5P7) is reported at 2.8 Å resolution. The structure was solved by molecular replacement and contains one polypeptide in the asymmetric unit. The structure was refined to an R free of 29%. The structure of XCC3289 consists of two domains joined by a long loop. The N-terminal domain (residues 1–112) consists of an α-helix surrounded by β-sheets, whereas the C-terminal domain (residues 123–193) is an α-helical bundle. The fold and spatial orientation of the two domains closely resembles those ...

Research paper thumbnail of Effect of Rapid Maxillary Expansion on Mandibular Rotation—A Systematic Review

Journal of Indian Orthodontic Society, 2020

Objective: To evaluate the effect of rapid maxillary expansion (RME) on mandibular rotation. Mate... more Objective: To evaluate the effect of rapid maxillary expansion (RME) on mandibular rotation. Materials and Method: A systematic review of articles selected from 4 electronic databases—PUBMED, Cochrane Central Register of Controlled Trials, Clinical Trials Registry, and Google Scholar—was carried out. Additional studies were hand-searched and retrieved from the reference lists of relevant articles. Studies published till August, 2019, were included in this study. Results: A total of 28 articles were identified through electronic database searching. 16 articles were obtained after elimination of duplicates which were then screened. Full-text articles were assessed according to the eligibility criteria. 2 randomized controlled trials (RCTs) and 14 clinical trials (CTs) were identified for inclusion in the review. These studies effectively highlighted the effect of RME on mandibular rotation, primarily in the clockwise direction. Conclusion: There is a moderate sum of evidence to illust...

Research paper thumbnail of Primary adenoid cystic carcinoma of the liver: A case report

International Journal of Molecular and Immuno Oncology, 2017

Adenoid cystic carcinoma (ACC) is primarily found in the salivary glands and rarely at other orga... more Adenoid cystic carcinoma (ACC) is primarily found in the salivary glands and rarely at other organs but never reported as liver primary. This is a very rare case of primary ACC of the liver which was not resectable and managed with chemotherapy and targeted therapy. The patient progressed on imatinib (c-kit positive) while responded to chemotherapy and gefitinib (epidermal growth factor receptor mutation absent).

Research paper thumbnail of Radiographic Assessment for Predicting the Mandibular Third Molar Eruption after Orthodontic Treatment in First Premolar Extraction Group and Non-Extraction Group: A-retrospective Study

International Journal of Dental Health Concerns, 2015

Introduction: The third molars are the most congenitally missing teeth. If present, they might fo... more Introduction: The third molars are the most congenitally missing teeth. If present, they might follow ectopic eruption path and become impacted. Because it is the last tooth erupt in the arch, and usually there is no space in the arch. Effects of orthodontic treatment may also affect the position of third molar after treatment and may changes the eruption pattern of third molar. Materials and Methods: 30 patient's pre-treatment and post-treatment lateral cephalogram and orthopantomogram (OPG) were taken out of which 15 patients were treated with first pre-molar extraction, and 15 patients were treated with non-extraction approach. Cephalomatric and OPG tracing were done at T1 (pre-treatment) and T2 (post-treatment). Distance from Xi-point to distal surface of second molar, distance from anterior border of ramus to the distal surface of second molar, angulation of third molar in relation with second molar and mesio-distal width of third molar were checked. Descriptive analysis was perform for both the groups and paired t-test and un-paired t-test were performed for first pre-molar extraction and nonextraction group with two different methods such as panoramic radiograph (OPG) and lateral cephalograms at significant level P < 0.05. Results: In extraction group, there were more possibility of the eruption, more mesial movement and more angulation changes noted compare to non-extraction group. Conclusion: Panoramic radiographs were more accurate when compared to lateral cephalogram while checking minor changes.

Research paper thumbnail of Effect of Saliva and Desensitizing agent on the Shear Bond Strength of Metal and Ceramic Brackets using Self Etching Primer and in Vitro Stud

Indian Journal of Contemporary Dentistry, 2015

Research paper thumbnail of Evaluation of Maxillary Interpremolar, Molar Width by DRNA Indices and Arch Dimension, Arch Form in Maratha Population

The Journal of Indian Orthodontic Society, 2013

Background and objectives: The present study is conducted to ascertain whether or not Pont's Inde... more Background and objectives: The present study is conducted to ascertain whether or not Pont's Index can be used reliably on Maratha individuals and if not, to establish the norms for the same. A mathematical model is also presented to individualize the nature of arch form. Materials and methods: Full mouth dental cast of 60 patients between ages 18 and 25 years were obtained belonging to Maharashtra and traced back to two generations. The different formulae were used to determine the premolar and molar indices of the maxillary arch width by using the sum of incisal widths of maxilla or mandible. Mathematical model was determined using fourth order polynomial. Results: Mean and standard deviation of premolar arch width and molar arch width for male is 37.59 ± 1.76 and 48.15 ± 2.16 and for females, it is 35.61 ± 1.66 and 46.12 ± 2.06 respectively. The premolar and molar indices derived from sum of maxillary incisors (SI max) are 80.29 ± 5.39 and 62.66 ± 4.0 for males and 82.33 ± 4.02 and 63.6 ± 3.62 for females respectively. The polynomial indicated that the arches were symmetrical. The arch dimensions showed variations in males and females. Conclusion: Significant correlation was found between the sum of maxillary incisors and interpremolar width but not with the intermolar width while sum of mandibular incisors showed significant correlation with the interpremolar and intermolar arch width. There is no single arch form unique to any of the ethnic groups. A new formula is proposed to determine the premolar and molar index.

Research paper thumbnail of An Unusual Presentation of Bilateral Vocal Fold Paralysis due to Spinal Muscular Atrophy

International Journal of Phonosurgery & Laryngology, 2014

Background Spinal muscular atrophy is a rare autosomal recessive neurodegenerative disorder. We r... more Background Spinal muscular atrophy is a rare autosomal recessive neurodegenerative disorder. We report a case of 62-year-old female of spinal muscular atrophy presenting with bilateral vocal fold paralysis, her diagnosis and management. Objective Case report of a case of spinal muscular atrophy presenting with bilateral vocal fold paralysis. Conclusion Spinomuscular atrophy though rarely associated with laryngeal symptoms should be kept in mind as a possible etiology of bilateral vocal fold paralysis. The surgical decision and the postoperative sequeale will be affected due to the presence of this disease and thus a high index of suspicion is required. How to cite this article Nerurkar NK, Deshmukh S, Agrawal P, Kulkarni P. An Unusual Presentation of Bilateral Vocal Fold Paralysis due to Spinal Muscular Atrophy. Int J Phonosurg Laryngol 2014;4(1):27-29.

Research paper thumbnail of Mean values of Steiner, Tweed, Ricketts and McNamara analysis in Maratha ethnic population: A cephalometric study

APOS Trends in Orthodontics, 2013

Objectives: Cephalometric norms derived for Caucasian population are routinely used for investiga... more Objectives: Cephalometric norms derived for Caucasian population are routinely used for investigations. As these norms show a great degree of variation when applied to different populations, it becomes necessary to establish the norms for every ethnic group. The present study was designed to derive norms for the Maratha ethnic population, which would be comparable in diagnosis and treatment planning, to the Steiner, Tweed, Ricketts and McNamara cephalometric analysis. Materials and Methods: The sample consisted of 60 adult subjects (30 males and 30 females) of Maratha ethnic origin. The age ranged between 18 and 26 years. The cephalograms of the subjects were subjected to Steiner, Tweed, Ricketts and McNamara cephalometric analysis and were complemented by a few additional readings. Result: The cephalometric norms for Steiner, Tweed, Ricketts and McNamara cephalometric analysis of the Maratha population differed significantly from the Caucasian population. Comparison of our sample with the other ethnic group reaffirmed the need to develop separate standards for different populations. Conclusion: Therefore, it is legitimate and important for those undertaking orthodontic treatment for patients of Maratha ethnicity to use cephalometric norms for Maratha ethnic population.

Research paper thumbnail of Elemental and Organic Carbon in Ambient Air of a Major Indian Urban Community

Bulletin of Environmental Contamination and Toxicology, 2010

Recent epidemiological studies have demonstrated associations between residential proximity to tr... more Recent epidemiological studies have demonstrated associations between residential proximity to traffic sources and adverse respiratory symptoms as the Diesel Exhaust Particulate surfaces act as a site for the concentration of thousands of organic compounds. Analysis of 24 h integrated samples of PM10 and PM2.5 collected at a kerb site in a major Indian urban community, heavily impacted by heavy commercial vehicles, showed elemental carbon concentrations higher (14.4-48.8 lg/m 3) than organic carbon (1.7-9.2 lg/m 3). The organic to elemental carbon ratio varied from 0.09 to 0.31. Average concentration of PM10 and PM2.5 ranged 133-492 lg/m 3 and 87-160 lg/m 3 , respectively.

Research paper thumbnail of Treatment of malpositioned periodontally compromised teeth by an interdisciplinary approach-A case report

Journal of the International Clinical …, 2009

... Treatment of malpositioned periodontally compromised teeth by an interdisciplinary approach -... more ... Treatment of malpositioned periodontally compromised teeth by an interdisciplinary approach - A case report Sonali Deshmukh 1 , Sanket Agarkar 1 , Amrita Kishore 2 1 Department of Orthodontics, Dr. DY Patil Dental College &amp;amp; Hospital, Pimpri, Pune, India 2 Department of ...

Research paper thumbnail of Cervicomental angle changes observed after mandibular advancement surgery – A systematic review

APOS Trends in Orthodontics, 2021

Purpose: In adults, correction of such a jaw base relation is done by bilateral sagittal split os... more Purpose: In adults, correction of such a jaw base relation is done by bilateral sagittal split osteotomy and mandibular advancement which often causes change in the cervicomental angle that might not be within the acceptable and aesthetic range. The objective of this systematic review was to evaluate the changes observed in cervicomental angle after mandibular advancement surgery. Data Sources: Based on the available data, we conducted an electronic database PubMed search, based on the search of published data from 1994 to 2017, six strategies were designed using two keywords, and four articles were shortlisted for systematic review. Study Eligibility Criteria: Studies that provide information on cervicomental angle changes after mandibular advancement surgery, published from 1994 to 2017. Results: The search yielded 168 articles, of which four were included based on the selection criteria. These articles described that the cervicomental angle observed after mandibular advancement s...

Research paper thumbnail of Mean values of Beta Angle and YEN Angle in Maratha ethnic population and their reliability on select local population: A cephalometric observational study

International journal of scientific research, 2017

Objective: Different ethnic groups present variations in the various cephalometric analyses that ... more Objective: Different ethnic groups present variations in the various cephalometric analyses that are performed to determine the sagittal relation. This study is aimed at establishing the norms for Beta angle and Yen angle in Maratha population and to evaluate their reliability in sagittal malocclusions from amongst select local population. Materials and Method: A total of 120 samples were divided into three categories. 60 samples of Class I normal occlusion (30 males and 30 females) were used to establish the norms. 60 samples with skeletal Class II and Class III relation were used for checking the reliability of the established norms. Lateral cephalogram of all the samples was procured and tracings were done to calculate ANB Angle, Wits appraisal, McNamara differential, Beta angle and Yen angle. Oneway ANOVA was done to determine the means of Beta and YEN angle in Maratha population. Results: The Maratha population norms for Beta angle is 31.50 +/- 2.70 and for YEN angle is 122.20 ...

Research paper thumbnail of Evaluation of Changes in Condylar Cartilage Thickness Using MRI and Ultrasound Imaging in Patients Treated by Mandibular Advancement With Myofunctional Appliance: An In-Vivo Pilot Study

Cureus, 2021

The changes occurring due to growth modulation of the condylar cartilage act as an important mech... more The changes occurring due to growth modulation of the condylar cartilage act as an important mechanism for mandibular advancement using myofunctional appliance therapy. So this study aims to evaluate the condylar cartilage thickness by using MRI and USG in patients undergoing myofunctional appliance therapy for mandibular advancement with the null hypothesis being that there are no changes seen in the thickness of condylar cartilage in growing children. Materials and methods A prospective evaluation of samples having skeletal Class-II malocclusion ranging between cervical vertebral maturation index (CVMI) stage II and III, requiring twin block functional therapy was performed. Ten patients were selected randomly who underwent MRI and USG in the open and close positions for the evaluation of condylar cartilage thickness and the dimensional changes in the width of the right and left condyle in mm at T0 and T1. Result There was no statistically significant difference between the values interpreted by MRI or USG imaging when compared at T0 and T1 and in the open and closed mouth on the left and right sides. At T0, the mean thickness noted was 0.49 mm and 0.48 mm during opening and closing on the left side and 0.52 mm in both positions on the right side. At T1, the mean thickness noted was 0.8 and 0.79mm during opening and closing on the left side, whereas it was 0.81 mm in both positions on the right side. Conclusion The condylar cartilage thickness increases significantly after twin block therapy suggestive of mandibular growth in skeletal class II malocclusion. It can be inferred that both MRI and USG carry equal diagnostic interpretation, as there was no statistically significant difference between the two imaging modalities.

Research paper thumbnail of Establishment of norms for crown angulation and inclination among Maratha population: Cross-Sectional Study

Objectives: Selection of an appropriate bracket prescription for any particular individual or pop... more Objectives: Selection of an appropriate bracket prescription for any particular individual or population facilitates idealistic and realistic goals for different esthetic around the world. As Caucasian norms show a great degree of variation when applied to different populations, it becomes necessary to establish the norms for every ethnic group. The present study was designed to derive norms of crown angulation and inclination for the Maratha ethnic population, which would be compared with Caucasian norms. Materials and Method: The sample consisted of 100 adult subjects (50 males and 50 females) of Maratha ethnic origin with traced back to two generations, age group of 18 years and above. Acceptable and straight profiles; Class I molar relation on both sides; with normal overjet and overbite; well aligned arches. Orthodontic Torque Angulation Device (TAD) was used to measure the crown angulation and inclination. Comparison of these values with those established by Andrews is done us...

Research paper thumbnail of Impact of the pandemic on cancer care: Lessons learnt from a rural cancer center in the first 3 months

Journal of Surgical Oncology, 2020

The COVID‐19 outbreak and the subsequent declaration of pandemic was an unprecedented event, whic... more The COVID‐19 outbreak and the subsequent declaration of pandemic was an unprecedented event, which created different complex situations for treatment of cancer patients. A critical assessment of the response to this calamity and its impact on healthcare workers (HCWs) and patient care in a dedicated cancer hospital is analyzed.

Research paper thumbnail of Clinical use of orthodontic mini-implants for intrusion and retraction: a systematic review

Australasian Orthodontic Journal, 2021

Background Bimaxillary dental protrusion is common in many ethnic groups and is generally treated... more Background Bimaxillary dental protrusion is common in many ethnic groups and is generally treated by the extraction of all first premolars. However, temporary anchorage devices (TADs) are currently gaining popularity and most studies have focused on anchorage loss, treatment duration, mini-implant success and failure rates, pain, discomfort and root resorption. Few studies have focused on the clinical effectiveness of implants for the intrusion and retraction of anterior teeth. Objectives To assess the clinical use of orthodontic mini-implants for the intrusion and retraction of anterior teeth. Methods A systematic review of articles selected from PUBMED and Google Scholar was carried out to determine the clinical use of orthodontic mini-implants for anterior tooth intrusion and retraction. Additional studies were hand searched to identify and include clinical trials, prospective and retrospective studies, while excluding finite element method (FEM) studies and case reports. A total...

Research paper thumbnail of Crystal structure of XCC3289 from Xanthomonas campestris: homology with the N-terminal substrate-binding domain of Lon peptidase

Acta Crystallographica Section F Structural Biology Communications, 2020

LonA peptidase is a major component of the protein quality-control mechanism in both prokaryotes ... more LonA peptidase is a major component of the protein quality-control mechanism in both prokaryotes and the organelles of eukaryotes. Proteins homologous to the N-terminal domain of LonA peptidase, but lacking its other domains, are conserved in several phyla of prokaryotes, including the Xanthomonadales order. However, the function of these homologous proteins (LonNTD-like proteins) is not known. Here, the crystal structure of the LonNTD-like protein from Xanthomonas campestris (XCC3289; UniProt Q8P5P7) is reported at 2.8 Å resolution. The structure was solved by molecular replacement and contains one polypeptide in the asymmetric unit. The structure was refined to an R free of 29%. The structure of XCC3289 consists of two domains joined by a long loop. The N-terminal domain (residues 1–112) consists of an α-helix surrounded by β-sheets, whereas the C-terminal domain (residues 123–193) is an α-helical bundle. The fold and spatial orientation of the two domains closely resembles those ...

Research paper thumbnail of Effect of Rapid Maxillary Expansion on Mandibular Rotation—A Systematic Review

Journal of Indian Orthodontic Society, 2020

Objective: To evaluate the effect of rapid maxillary expansion (RME) on mandibular rotation. Mate... more Objective: To evaluate the effect of rapid maxillary expansion (RME) on mandibular rotation. Materials and Method: A systematic review of articles selected from 4 electronic databases—PUBMED, Cochrane Central Register of Controlled Trials, Clinical Trials Registry, and Google Scholar—was carried out. Additional studies were hand-searched and retrieved from the reference lists of relevant articles. Studies published till August, 2019, were included in this study. Results: A total of 28 articles were identified through electronic database searching. 16 articles were obtained after elimination of duplicates which were then screened. Full-text articles were assessed according to the eligibility criteria. 2 randomized controlled trials (RCTs) and 14 clinical trials (CTs) were identified for inclusion in the review. These studies effectively highlighted the effect of RME on mandibular rotation, primarily in the clockwise direction. Conclusion: There is a moderate sum of evidence to illust...

Research paper thumbnail of Primary adenoid cystic carcinoma of the liver: A case report

International Journal of Molecular and Immuno Oncology, 2017

Adenoid cystic carcinoma (ACC) is primarily found in the salivary glands and rarely at other orga... more Adenoid cystic carcinoma (ACC) is primarily found in the salivary glands and rarely at other organs but never reported as liver primary. This is a very rare case of primary ACC of the liver which was not resectable and managed with chemotherapy and targeted therapy. The patient progressed on imatinib (c-kit positive) while responded to chemotherapy and gefitinib (epidermal growth factor receptor mutation absent).

Research paper thumbnail of Radiographic Assessment for Predicting the Mandibular Third Molar Eruption after Orthodontic Treatment in First Premolar Extraction Group and Non-Extraction Group: A-retrospective Study

International Journal of Dental Health Concerns, 2015

Introduction: The third molars are the most congenitally missing teeth. If present, they might fo... more Introduction: The third molars are the most congenitally missing teeth. If present, they might follow ectopic eruption path and become impacted. Because it is the last tooth erupt in the arch, and usually there is no space in the arch. Effects of orthodontic treatment may also affect the position of third molar after treatment and may changes the eruption pattern of third molar. Materials and Methods: 30 patient's pre-treatment and post-treatment lateral cephalogram and orthopantomogram (OPG) were taken out of which 15 patients were treated with first pre-molar extraction, and 15 patients were treated with non-extraction approach. Cephalomatric and OPG tracing were done at T1 (pre-treatment) and T2 (post-treatment). Distance from Xi-point to distal surface of second molar, distance from anterior border of ramus to the distal surface of second molar, angulation of third molar in relation with second molar and mesio-distal width of third molar were checked. Descriptive analysis was perform for both the groups and paired t-test and un-paired t-test were performed for first pre-molar extraction and nonextraction group with two different methods such as panoramic radiograph (OPG) and lateral cephalograms at significant level P < 0.05. Results: In extraction group, there were more possibility of the eruption, more mesial movement and more angulation changes noted compare to non-extraction group. Conclusion: Panoramic radiographs were more accurate when compared to lateral cephalogram while checking minor changes.

Research paper thumbnail of Effect of Saliva and Desensitizing agent on the Shear Bond Strength of Metal and Ceramic Brackets using Self Etching Primer and in Vitro Stud

Indian Journal of Contemporary Dentistry, 2015

Research paper thumbnail of Evaluation of Maxillary Interpremolar, Molar Width by DRNA Indices and Arch Dimension, Arch Form in Maratha Population

The Journal of Indian Orthodontic Society, 2013

Background and objectives: The present study is conducted to ascertain whether or not Pont's Inde... more Background and objectives: The present study is conducted to ascertain whether or not Pont's Index can be used reliably on Maratha individuals and if not, to establish the norms for the same. A mathematical model is also presented to individualize the nature of arch form. Materials and methods: Full mouth dental cast of 60 patients between ages 18 and 25 years were obtained belonging to Maharashtra and traced back to two generations. The different formulae were used to determine the premolar and molar indices of the maxillary arch width by using the sum of incisal widths of maxilla or mandible. Mathematical model was determined using fourth order polynomial. Results: Mean and standard deviation of premolar arch width and molar arch width for male is 37.59 ± 1.76 and 48.15 ± 2.16 and for females, it is 35.61 ± 1.66 and 46.12 ± 2.06 respectively. The premolar and molar indices derived from sum of maxillary incisors (SI max) are 80.29 ± 5.39 and 62.66 ± 4.0 for males and 82.33 ± 4.02 and 63.6 ± 3.62 for females respectively. The polynomial indicated that the arches were symmetrical. The arch dimensions showed variations in males and females. Conclusion: Significant correlation was found between the sum of maxillary incisors and interpremolar width but not with the intermolar width while sum of mandibular incisors showed significant correlation with the interpremolar and intermolar arch width. There is no single arch form unique to any of the ethnic groups. A new formula is proposed to determine the premolar and molar index.

Research paper thumbnail of An Unusual Presentation of Bilateral Vocal Fold Paralysis due to Spinal Muscular Atrophy

International Journal of Phonosurgery & Laryngology, 2014

Background Spinal muscular atrophy is a rare autosomal recessive neurodegenerative disorder. We r... more Background Spinal muscular atrophy is a rare autosomal recessive neurodegenerative disorder. We report a case of 62-year-old female of spinal muscular atrophy presenting with bilateral vocal fold paralysis, her diagnosis and management. Objective Case report of a case of spinal muscular atrophy presenting with bilateral vocal fold paralysis. Conclusion Spinomuscular atrophy though rarely associated with laryngeal symptoms should be kept in mind as a possible etiology of bilateral vocal fold paralysis. The surgical decision and the postoperative sequeale will be affected due to the presence of this disease and thus a high index of suspicion is required. How to cite this article Nerurkar NK, Deshmukh S, Agrawal P, Kulkarni P. An Unusual Presentation of Bilateral Vocal Fold Paralysis due to Spinal Muscular Atrophy. Int J Phonosurg Laryngol 2014;4(1):27-29.

Research paper thumbnail of Mean values of Steiner, Tweed, Ricketts and McNamara analysis in Maratha ethnic population: A cephalometric study

APOS Trends in Orthodontics, 2013

Objectives: Cephalometric norms derived for Caucasian population are routinely used for investiga... more Objectives: Cephalometric norms derived for Caucasian population are routinely used for investigations. As these norms show a great degree of variation when applied to different populations, it becomes necessary to establish the norms for every ethnic group. The present study was designed to derive norms for the Maratha ethnic population, which would be comparable in diagnosis and treatment planning, to the Steiner, Tweed, Ricketts and McNamara cephalometric analysis. Materials and Methods: The sample consisted of 60 adult subjects (30 males and 30 females) of Maratha ethnic origin. The age ranged between 18 and 26 years. The cephalograms of the subjects were subjected to Steiner, Tweed, Ricketts and McNamara cephalometric analysis and were complemented by a few additional readings. Result: The cephalometric norms for Steiner, Tweed, Ricketts and McNamara cephalometric analysis of the Maratha population differed significantly from the Caucasian population. Comparison of our sample with the other ethnic group reaffirmed the need to develop separate standards for different populations. Conclusion: Therefore, it is legitimate and important for those undertaking orthodontic treatment for patients of Maratha ethnicity to use cephalometric norms for Maratha ethnic population.

Research paper thumbnail of Elemental and Organic Carbon in Ambient Air of a Major Indian Urban Community

Bulletin of Environmental Contamination and Toxicology, 2010

Recent epidemiological studies have demonstrated associations between residential proximity to tr... more Recent epidemiological studies have demonstrated associations between residential proximity to traffic sources and adverse respiratory symptoms as the Diesel Exhaust Particulate surfaces act as a site for the concentration of thousands of organic compounds. Analysis of 24 h integrated samples of PM10 and PM2.5 collected at a kerb site in a major Indian urban community, heavily impacted by heavy commercial vehicles, showed elemental carbon concentrations higher (14.4-48.8 lg/m 3) than organic carbon (1.7-9.2 lg/m 3). The organic to elemental carbon ratio varied from 0.09 to 0.31. Average concentration of PM10 and PM2.5 ranged 133-492 lg/m 3 and 87-160 lg/m 3 , respectively.

Research paper thumbnail of Treatment of malpositioned periodontally compromised teeth by an interdisciplinary approach-A case report

Journal of the International Clinical …, 2009

... Treatment of malpositioned periodontally compromised teeth by an interdisciplinary approach -... more ... Treatment of malpositioned periodontally compromised teeth by an interdisciplinary approach - A case report Sonali Deshmukh 1 , Sanket Agarkar 1 , Amrita Kishore 2 1 Department of Orthodontics, Dr. DY Patil Dental College &amp;amp; Hospital, Pimpri, Pune, India 2 Department of ...