Stefano Maria Serini - Academia.edu (original) (raw)

Papers by Stefano Maria Serini

Research paper thumbnail of The efficacy and tolerability of 5-aminolevulinic acid 5% thermosetting gel photodynamic therapy (PDT) in the treatment of mild-to-moderate acne vulgaris. A two-center, prospective assessor-blinded, proof-of-concept study

Journal of cosmetic dermatology, Jan 22, 2018

Acne vulgaris is a chronic inflammatory skin disease, commonly treated with topical or systemic d... more Acne vulgaris is a chronic inflammatory skin disease, commonly treated with topical or systemic drugs, according to the severity of the condition. Retinoids and antibiotic compounds are considered cornerstone approaches in this condition. However, low adherence to the therapy and the issue of bacterial resistance undermine the efficacy in the long term. Photodynamic therapy (PDT) with 20% aminolevulinic acid (ALA) has shown to be effective in the treatment of inflammatory acne. Skin tolerability, however, could be a limiting factor for a widespread use of this approach. A new formulation of 5% ALA in thermosetting gel has been recently available. This formulation allows a more convenient application procedure without occlusion and better and more efficient release of the active compound in comparison with traditional ALA formulations like creams or ointments. To evaluate in a two-center, assessor-blinded, prospective, proof-of-concept study, the efficacy, and tolerability of red-lig...

Research paper thumbnail of Onychomycosis caused by Aspergillus terreus

Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia, 2016

Research paper thumbnail of Peristomal bullous pemphigoid

The Journal of Dermatology, Sep 1, 2010

Research paper thumbnail of Treatment of crusted scabies with acitretin

The British journal of dermatology, Jan 17, 2015

We present two cases of crusted scabies who were successfully treated with acitretin. Case 1. An ... more We present two cases of crusted scabies who were successfully treated with acitretin. Case 1. An 83-year-old woman was admitted to our Department because of a crusted dermatitis. The patient stated that she was in therapy with metoprolol and levodopa/benserazide for essential arterial hypertension and Parkinson's disease. The patient also stated that the dermatitis had appeared approximately six months earlier. It was diagnosed at other centres as allergic contact dermatitis and unsuccessfully treated with topical and oral corticosteroids, and oral anti-histamines. This article is protected by copyright. All rights reserved.

Research paper thumbnail of Sclerodermus domesticus infestation

Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia, 2010

Sclerodermus domesticus is an insect belonging to the order Hymenoptera. Female of S. domesticus ... more Sclerodermus domesticus is an insect belonging to the order Hymenoptera. Female of S. domesticus feeds on larvae of xylophagous Coleoptera and Lepidoptera living in the galleries they dig in old wooden furniture. Human infestation is rare. In the last few months, we observed nine adult patients (7 males and 2 females) who were affected by S. domesticus infestation. Seven patients were antiquarians or restorers and two were housewives. The rash was characterized by erythematous-papular lesions, accompanied by pruritus and/or pain. In addition, 7 patients reported general malaise and fever. In all cases it was possible to find specimens of S. domesticus in furniture or house dust. Complete remission was obtained with topical corticosteroids, oral anti-histamines and pest control of furniture. Antiquarians and restorers and, in general, the people in close contact with furniture infested by S. domesticus may be stung by these insects. S. domesticus infestation can therefore be consider...

Research paper thumbnail of Sclerodermus domesticus infestation: an occupational disease in antiquarians and restorers

Dermatitis : contact, atopic, occupational, drug

... Sclerodermus domesticus Infestation: An Occupational Disease in Antiquarians and Restorers. V... more ... Sclerodermus domesticus Infestation: An Occupational Disease in Antiquarians and Restorers. Veraldi, Stefano; Maria, Stefano; Silvia, Serini; Violetti, Alberti. Article Outline. Collapse Box ... al. Urticaria induced by Scleroderma domesticum: case report. Allergy 1996;51 Suppl:168. ...

Research paper thumbnail of Mycosis fungoides mimicking erythema gyratum repens: an additional variant?

European journal of dermatology : EJD

... di Milano-Bicocca. Pictures. ARTICLE. Auteur(s) : Amilcare Cerri 1 , Pamela Vezzoli 2 , Stefa... more ... di Milano-Bicocca. Pictures. ARTICLE. Auteur(s) : Amilcare Cerri 1 , Pamela Vezzoli 2 , Stefano M Serini 2 , Carlo Crosti 2 , Emilio Berti 3 , Angelo V Marzano 2. 1 Dipartimento di ... presentation of MF. Jouary et al. [8] reported an ...

Research paper thumbnail of Three cases of cutaneous myiasis caused by Cordylobia rodhaini

The Journal of Infection in Developing Countries, 2014

Cordylobia sp. is a fly belonging to the Calliphoridae family. Three species of Cordylobia are kn... more Cordylobia sp. is a fly belonging to the Calliphoridae family. Three species of Cordylobia are known: C. anthropophaga, C. rodhaini and C. ruandae. The C. rodhaini Gedoelst 1909 lives in Sub-Saharan Africa, especially in rain forest areas. Usual hosts are rodents and antelopes. Humans are accidentally infested. Myiasis caused by C. rodhaini has been very rarely reported in the literature. We present three cases of C. rodhaini myiasis acquired in Ethiopia and Uganda.

Research paper thumbnail of Cutaneous lupus erythematosus induced by adalimumab

The Journal of Dermatology, 2010

Research paper thumbnail of Peristomal bullous pemphigoid

The Journal of Dermatology, 2010

Research paper thumbnail of Cutaneous Abscess After Conus textile Sting

Journal of Travel Medicine, 2011

We present a 31-year-old man who, after a Conus textile sting acquired in New Caledonia, develope... more We present a 31-year-old man who, after a Conus textile sting acquired in New Caledonia, developed a cutaneous abscess on a buttock. The abscess was accompanied by pain, paraesthesia, general malaise, and fever. Complete remission was achieved by sodium hypochlorite packs and oral amoxicillin/clavulanic acid, metronidazole, and tramadol.

Research paper thumbnail of The use of esmolol to treat systolic anterior motion of the mitral valve after mitral valve repair

European Journal of Anaesthesiology, 2008

... G. Crescenzi, C. Rosica, G. Marino, SM Serini RD Covello, G. Landoni, A. Zangrillo Department... more ... G. Crescenzi, C. Rosica, G. Marino, SM Serini RD Covello, G. Landoni, A. Zangrillo Department of Cardiothoracic Anesthesia and Intensive Care Istituto Scientifico San Raffaele Universita` Vita-Salute ... Le Club Mitrale Newsl 1988; 1: 5. 2. Mascagni R, Al Attar N, Lamarra M et al. ...

Research paper thumbnail of Long‐term follow‐up of metil aminolevulinate (MAL)‐PDT in difficult‐to‐treat cutaneous Bowen's disease

International journal …, 2011

Bowen's disease (... more Bowen's disease (BD) is a form of intraepidermal squamous cell carcinoma, which is clinically characterized by gradually enlarging, well-demarcated erythematous plaques with irregular borders and surface crusting or scaling, affecting primarily the elderly. BD often presents with lesions difficult to treat with standard therapy as surgery, cryosurgery, or 5-fluorouracil (5-FU) for the risk of significantly poor cosmetic outcome, failure rate, and adverse events, related mainly to the age of the patients. Topical PDT with methyl aminolevulinate (MAL) represents a valid and approved therapy for BD lesions in many cases, especially for lesions located at poor healing sites or for large patches of disease, due to its high efficacy coupled with good tolerability and tissue-sparing attitude. In this study, we sought to investigate the efficacy, safety, and cosmetic outcome of MAL-PDT in a series of patients with BD lesions which were challenging to treat for clinical, surgical, and patient-related reasons, such as size of the lesion, difficult surgical approach for anatomical sites, or age of patients and request of the best cosmetic result. We also performed a long-term follow-up to assess recurrence rates and eventual late-onset adverse events.

Research paper thumbnail of The efficacy and tolerability of 5-aminolevulinic acid 5% thermosetting gel photodynamic therapy (PDT) in the treatment of mild-to-moderate acne vulgaris. A two-center, prospective assessor-blinded, proof-of-concept study

Journal of cosmetic dermatology, Jan 22, 2018

Acne vulgaris is a chronic inflammatory skin disease, commonly treated with topical or systemic d... more Acne vulgaris is a chronic inflammatory skin disease, commonly treated with topical or systemic drugs, according to the severity of the condition. Retinoids and antibiotic compounds are considered cornerstone approaches in this condition. However, low adherence to the therapy and the issue of bacterial resistance undermine the efficacy in the long term. Photodynamic therapy (PDT) with 20% aminolevulinic acid (ALA) has shown to be effective in the treatment of inflammatory acne. Skin tolerability, however, could be a limiting factor for a widespread use of this approach. A new formulation of 5% ALA in thermosetting gel has been recently available. This formulation allows a more convenient application procedure without occlusion and better and more efficient release of the active compound in comparison with traditional ALA formulations like creams or ointments. To evaluate in a two-center, assessor-blinded, prospective, proof-of-concept study, the efficacy, and tolerability of red-lig...

Research paper thumbnail of Onychomycosis caused by Aspergillus terreus

Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia, 2016

Research paper thumbnail of Peristomal bullous pemphigoid

The Journal of Dermatology, Sep 1, 2010

Research paper thumbnail of Treatment of crusted scabies with acitretin

The British journal of dermatology, Jan 17, 2015

We present two cases of crusted scabies who were successfully treated with acitretin. Case 1. An ... more We present two cases of crusted scabies who were successfully treated with acitretin. Case 1. An 83-year-old woman was admitted to our Department because of a crusted dermatitis. The patient stated that she was in therapy with metoprolol and levodopa/benserazide for essential arterial hypertension and Parkinson's disease. The patient also stated that the dermatitis had appeared approximately six months earlier. It was diagnosed at other centres as allergic contact dermatitis and unsuccessfully treated with topical and oral corticosteroids, and oral anti-histamines. This article is protected by copyright. All rights reserved.

Research paper thumbnail of Sclerodermus domesticus infestation

Giornale italiano di dermatologia e venereologia : organo ufficiale, Società italiana di dermatologia e sifilografia, 2010

Sclerodermus domesticus is an insect belonging to the order Hymenoptera. Female of S. domesticus ... more Sclerodermus domesticus is an insect belonging to the order Hymenoptera. Female of S. domesticus feeds on larvae of xylophagous Coleoptera and Lepidoptera living in the galleries they dig in old wooden furniture. Human infestation is rare. In the last few months, we observed nine adult patients (7 males and 2 females) who were affected by S. domesticus infestation. Seven patients were antiquarians or restorers and two were housewives. The rash was characterized by erythematous-papular lesions, accompanied by pruritus and/or pain. In addition, 7 patients reported general malaise and fever. In all cases it was possible to find specimens of S. domesticus in furniture or house dust. Complete remission was obtained with topical corticosteroids, oral anti-histamines and pest control of furniture. Antiquarians and restorers and, in general, the people in close contact with furniture infested by S. domesticus may be stung by these insects. S. domesticus infestation can therefore be consider...

Research paper thumbnail of Sclerodermus domesticus infestation: an occupational disease in antiquarians and restorers

Dermatitis : contact, atopic, occupational, drug

... Sclerodermus domesticus Infestation: An Occupational Disease in Antiquarians and Restorers. V... more ... Sclerodermus domesticus Infestation: An Occupational Disease in Antiquarians and Restorers. Veraldi, Stefano; Maria, Stefano; Silvia, Serini; Violetti, Alberti. Article Outline. Collapse Box ... al. Urticaria induced by Scleroderma domesticum: case report. Allergy 1996;51 Suppl:168. ...

Research paper thumbnail of Mycosis fungoides mimicking erythema gyratum repens: an additional variant?

European journal of dermatology : EJD

... di Milano-Bicocca. Pictures. ARTICLE. Auteur(s) : Amilcare Cerri 1 , Pamela Vezzoli 2 , Stefa... more ... di Milano-Bicocca. Pictures. ARTICLE. Auteur(s) : Amilcare Cerri 1 , Pamela Vezzoli 2 , Stefano M Serini 2 , Carlo Crosti 2 , Emilio Berti 3 , Angelo V Marzano 2. 1 Dipartimento di ... presentation of MF. Jouary et al. [8] reported an ...

Research paper thumbnail of Three cases of cutaneous myiasis caused by Cordylobia rodhaini

The Journal of Infection in Developing Countries, 2014

Cordylobia sp. is a fly belonging to the Calliphoridae family. Three species of Cordylobia are kn... more Cordylobia sp. is a fly belonging to the Calliphoridae family. Three species of Cordylobia are known: C. anthropophaga, C. rodhaini and C. ruandae. The C. rodhaini Gedoelst 1909 lives in Sub-Saharan Africa, especially in rain forest areas. Usual hosts are rodents and antelopes. Humans are accidentally infested. Myiasis caused by C. rodhaini has been very rarely reported in the literature. We present three cases of C. rodhaini myiasis acquired in Ethiopia and Uganda.

Research paper thumbnail of Cutaneous lupus erythematosus induced by adalimumab

The Journal of Dermatology, 2010

Research paper thumbnail of Peristomal bullous pemphigoid

The Journal of Dermatology, 2010

Research paper thumbnail of Cutaneous Abscess After Conus textile Sting

Journal of Travel Medicine, 2011

We present a 31-year-old man who, after a Conus textile sting acquired in New Caledonia, develope... more We present a 31-year-old man who, after a Conus textile sting acquired in New Caledonia, developed a cutaneous abscess on a buttock. The abscess was accompanied by pain, paraesthesia, general malaise, and fever. Complete remission was achieved by sodium hypochlorite packs and oral amoxicillin/clavulanic acid, metronidazole, and tramadol.

Research paper thumbnail of The use of esmolol to treat systolic anterior motion of the mitral valve after mitral valve repair

European Journal of Anaesthesiology, 2008

... G. Crescenzi, C. Rosica, G. Marino, SM Serini RD Covello, G. Landoni, A. Zangrillo Department... more ... G. Crescenzi, C. Rosica, G. Marino, SM Serini RD Covello, G. Landoni, A. Zangrillo Department of Cardiothoracic Anesthesia and Intensive Care Istituto Scientifico San Raffaele Universita` Vita-Salute ... Le Club Mitrale Newsl 1988; 1: 5. 2. Mascagni R, Al Attar N, Lamarra M et al. ...

Research paper thumbnail of Long‐term follow‐up of metil aminolevulinate (MAL)‐PDT in difficult‐to‐treat cutaneous Bowen's disease

International journal …, 2011

Bowen's disease (... more Bowen's disease (BD) is a form of intraepidermal squamous cell carcinoma, which is clinically characterized by gradually enlarging, well-demarcated erythematous plaques with irregular borders and surface crusting or scaling, affecting primarily the elderly. BD often presents with lesions difficult to treat with standard therapy as surgery, cryosurgery, or 5-fluorouracil (5-FU) for the risk of significantly poor cosmetic outcome, failure rate, and adverse events, related mainly to the age of the patients. Topical PDT with methyl aminolevulinate (MAL) represents a valid and approved therapy for BD lesions in many cases, especially for lesions located at poor healing sites or for large patches of disease, due to its high efficacy coupled with good tolerability and tissue-sparing attitude. In this study, we sought to investigate the efficacy, safety, and cosmetic outcome of MAL-PDT in a series of patients with BD lesions which were challenging to treat for clinical, surgical, and patient-related reasons, such as size of the lesion, difficult surgical approach for anatomical sites, or age of patients and request of the best cosmetic result. We also performed a long-term follow-up to assess recurrence rates and eventual late-onset adverse events.