Walmir Francelino Motta - Academia.edu (original) (raw)
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Papers by Walmir Francelino Motta
Journal of Clinical Oncology, 2013
e16036 Background: Recombinant (rec) poxviruses have been developed as therapeutic cancer vaccine... more e16036 Background: Recombinant (rec) poxviruses have been developed as therapeutic cancer vaccines. A multi-institutional, randomized phase II trial of poxviral vaccine, PROSTVAC-V/F, suggested an improvement in median overall survival in men with metastatic castration resistant prostate cancer. A phase III trial in this same population is accruing. Accumulating data suggest a favorable safety profile of the poxviral vaccines (vacs). Methods: We reviewed all vaccine injections (inj) from 297 patients (pts) in 9 clinical trials involving poxviral vaccines. Vacs consisted of rec vaccinia and rec fowlpox encoded with 3 human costimulatory molecules (TRICOM), and a) prostate specific antigen, or b) carcinoembryonic antigen +/-mucin-1. Vacs were administered at doses between 1.2x108 to 2x109 pfu, subcutaneously, in all pts. 21 pts were also vaccinated intra-tumorally. 84 pts received concurrent treatments, such as radiation, celecoxib, ipilimumab, samarium-153, or flutamide in 4 of these...
Enfoque: Reflexão Contábil, 2006
Brazilian Journal of Development
Motivações para a adoção ou não da depreciação para bens do ativo imobilizado na gestão pública M... more Motivações para a adoção ou não da depreciação para bens do ativo imobilizado na gestão pública Motivations for the adoption or not of the depreciation for the permanent assets in the public management
Journal of Clinical Oncology, 2013
e16036 Background: Recombinant (rec) poxviruses have been developed as therapeutic cancer vaccine... more e16036 Background: Recombinant (rec) poxviruses have been developed as therapeutic cancer vaccines. A multi-institutional, randomized phase II trial of poxviral vaccine, PROSTVAC-V/F, suggested an improvement in median overall survival in men with metastatic castration resistant prostate cancer. A phase III trial in this same population is accruing. Accumulating data suggest a favorable safety profile of the poxviral vaccines (vacs). Methods: We reviewed all vaccine injections (inj) from 297 patients (pts) in 9 clinical trials involving poxviral vaccines. Vacs consisted of rec vaccinia and rec fowlpox encoded with 3 human costimulatory molecules (TRICOM), and a) prostate specific antigen, or b) carcinoembryonic antigen +/-mucin-1. Vacs were administered at doses between 1.2x108 to 2x109 pfu, subcutaneously, in all pts. 21 pts were also vaccinated intra-tumorally. 84 pts received concurrent treatments, such as radiation, celecoxib, ipilimumab, samarium-153, or flutamide in 4 of these...
Enfoque: Reflexão Contábil, 2006
Brazilian Journal of Development
Motivações para a adoção ou não da depreciação para bens do ativo imobilizado na gestão pública M... more Motivações para a adoção ou não da depreciação para bens do ativo imobilizado na gestão pública Motivations for the adoption or not of the depreciation for the permanent assets in the public management