Yifeng Tong - Academia.edu (original) (raw)
Papers by Yifeng Tong
Chinese Journal of Trauma, 2006
Objective To discuss the surgical outcome and operative technique of the modified trans-petrosal ... more Objective To discuss the surgical outcome and operative technique of the modified trans-petrosal presigmoid approach in treating cases with facial nerve palsy after petral bone fracture trea- ted with facial nerve canal decompression method.Methods A total of 15 cases with facial nerve pal- sy were treated with traumatic facial nerve canal decompression technique with the trans-petrosal presig- mold approach combined with high-dose hormone therapy,whereas 12 cases were treated with traditional Chinese medicine.The clinical data were analysed and compared retrospectively according to House- Brackmann facial nerve grading scale.Results At acute stage,eight(53.3%)out of 15 cases recov- ered to levelⅠ(P＜0.05),with no significant postoperative complications such as CSF leakage. Conclusions This approach is simple and safe and can expose extensively the facial nerve bone canal and effectively alleviate the edemous facial nerve aided by high-dose hormone therapy.Therefore,it is suitable for surgical treatment of acute facial nerve palsy after petral bone fractures.
ACS Applied Materials & Interfaces, Dec 7, 2022
Copper coated Bi 0.5 Sb 1.5 Te 3 powders were prepared through electroless plating with simplifie... more Copper coated Bi 0.5 Sb 1.5 Te 3 powders were prepared through electroless plating with simplified pretreatment method. After hydrogen reduction, the powders are consolidated into bulk by spark plasma sintering. The lowest lattice thermal conductivity in Bi 0.5 Sb 1.5 Te 3 /Cu reduces to 0.25 W/m•K at 371.5 K after annealing. The figure of merit (ZT) of Bi 0.5 Sb 1.5 Te 3 /Cu ascends in a large scale and reaches 1.08 at 373 K and 423 K before and after annealing respectively. The average ZT values of Bi 0.5 Sb 1.5 Te 3 /Cu samples both rise from 0.36 to 0.82, which makes this material suitable for application in a wide temperature range.
Chinese journal of otorhinolaryngology head and neck surgery, Jul 1, 2010
Objective: To evaluate the feasibility of endoscopic surgery using the low-temperature plasma rad... more Objective: To evaluate the feasibility of endoscopic surgery using the low-temperature plasma radiofrequency for nasopharyngeal angiofibroma (NA). Methods: The clinical data of 4 patients treated between December 2005 and August 2009 were retrospectively analyzed. The tumor in one patient was at stage I and three patients were at stage II, all these patients were treated by endoscopic surgery using the low-temperature plasma radiofrequency under controlled hypotension anesthesia. Preoperative angiography and embolisation were underwent in all patients. Bipolar coagulation was used to help hemostasis during operation. Results: The tumor in all 4 patients was completely removed. The operation time was 60, 80, 110, 90 min respectively. The blood loss was 250, 250, 320, 280 ml respectively. Neither blood transfusion nor complications were encountered perioperatively. Follow-up ranged from 6 months to 4 years, none of the patients recurred. Conclusions: Endoscopic surgery using low-temperature plasma radiofrequency for nasopharyngeal angiofibroma has many advantages such as less bleeding and total tumor removal. It is a minimally invasive surgical method for nasopharyngeal angiofibroma.
Studies in Law and Justice
The launch of ChatGPT marks a breakthrough in the development of generative artificial intelligen... more The launch of ChatGPT marks a breakthrough in the development of generative artificial intelligence (generative AI) technology, which is based on the collection and learning of big data as its core operating mechanism. Now the generative AI has the characteristics of high intelligence and high generalization and thus has led to various criminal risks. The current criminal law norms are inadequate in terms of the attribution system and crime norms for the criminal risks caused by the generative AI technologies. Thus, we should clarify the types of risks and governance challenges of generative AI, clarify that data is the object of risk governance, and establish a pluralistic liability allocation mechanism and a mixed legal governance framework of criminal, civil, and administrative law on this basis.
Scripta Materialia, 2016
eAg nanocomposites were fabricated using a chemical plating method and then compacted via spark p... more eAg nanocomposites were fabricated using a chemical plating method and then compacted via spark plasma sintering at 673 K and 50 MPa for 5 min. The effects of TiO 2 eAg nanoparticles (NPs) dispersed into Bi 0.4 Sb 1.6 Te 3 on the thermoelectric and mechanical properties were investigated. The results demonstrated that the carrier concentration and electrical conductivity increased by the incorporation of TiO 2 eAg NPs. Moreover, the addition of TiO 2 eAg NPs also changed the Fermi level positions and the maximum ZT could be obtained in the temperature range of 300-500 K. The maximum ZT value for a Bi 0.4 Sb 1.6 Te 3 /TiO 2 eAg (0.25 wt %) sample was 1.19 at 375 K due primarily to a significant increase in the power factor and an appropriate thermal conductivity. Consequently, the thermoelectric and mechanical properties were improved by embedding the TiO 2 eAg NPs into the Bi 0.4 Sb 1.6 Te 3 matrix.
American Journal of Translational Research, 2022
Frontiers in Cellular Neuroscience, 2020
Myelin membranes are dominated by lipids while the complexity of their protein composition has lo... more Myelin membranes are dominated by lipids while the complexity of their protein composition has long been considered to be low. However, numerous additional myelin proteins have been identified since. Here we revisit the proteome of myelin biochemically purified from the brains of healthy c56Bl/6N-mice utilizing complementary proteomic approaches for deep qualitative and quantitative coverage. By gel-free, label-free mass spectrometry, the most abundant myelin proteins PLP, MBP, CNP, and MOG constitute 38, 30, 5, and 1% of the total myelin protein, respectively. The relative abundance of myelin proteins displays a dynamic range of over four orders of magnitude, implying that PLP and MBP have overshadowed less abundant myelin constituents in initial gel-based approaches. By comparisons with published datasets we evaluate to which degree the CNS myelin proteome correlates with the mRNA and protein abundance profiles of myelin and oligodendrocytes. Notably, the myelin proteome displays only minor changes if assessed after a post-mortem delay of 6 h. These data provide the most comprehensive proteome resource of CNS myelin so far and a basis for addressing proteomic heterogeneity of myelin in mouse models and human patients with white matter disorders.
Oligodendrocytes, 2019
Molecular characterization of myelin is a prerequisite for understanding the normal structure of ... more Molecular characterization of myelin is a prerequisite for understanding the normal structure of the axon/ myelin-unit in the healthy nervous system and abnormalities in myelin-related disorders. However, reliable molecular profiles necessitate very pure myelin membranes, in particular when considering the power of highly sensitive "omics"-data acquisition methods. Here, we recapitulate the history and recent applications of myelin purification. We then provide our laboratory protocols for the biochemical isolation of a highly pure myelin-enriched fraction from mouse brains and for its proteomic analysis. We also supply methodological modifications when investigating posttranslational modifications, RNA, or myelin from peripheral nerves. Notably, technical advancements in solubilizing myelin are beneficial for gel-based and gel-free myelin proteome analyses. We conclude this article by exemplifying the exceptional power of label-free proteomics in the mass-spectrometric quantification of myelin proteins.
Proteomes, Jan 12, 2017
Post-translational modifications (PTMs) play a key role in regulating protein function, yet their... more Post-translational modifications (PTMs) play a key role in regulating protein function, yet their identification is technically demanding. Here, we present a straightforward workflow to systematically identify post-translationally modified proteins based on two-dimensional gel electrophoresis. Upon colloidal Coomassie staining the proteins are partially transferred, and the investigated PTMs are immunodetected. This strategy allows tracking back the immunopositive antigens to the corresponding spots on the original gel, from which they are excised and mass spectrometrically identified. Candidate proteins are validated on the same membrane by immunodetection using a second fluorescence channel. We exemplify the power of partial immunoblotting with the identification of lysine-acetylated proteins in myelin, the oligodendroglial membrane that insulates neuronal axons. The excellent consistency of the detected fluorescence signals at all levels allows the differential comparison of PTMs...
Journal of Neuroscience, 2007
Mice lacking the expression of proteolipid protein (PLP)/DM20 in oligodendrocytes provide a genui... more Mice lacking the expression of proteolipid protein (PLP)/DM20 in oligodendrocytes provide a genuine model for spastic paraplegia (SPG-2). Their axons are well myelinated but exhibit impaired axonal transport and progressive degeneration, which is difficult to attribute to the absence of a single myelin protein. We hypothesized that secondary molecular changes in PLP null myelin contribute to the loss of PLP/DM20-dependent neuroprotection and provide more insight into glia-axonal interactions in this disease model. By gel-based proteome analysis, we identified Ͼ160 proteins in purified myelin membranes, which allowed us to systematically monitor the CNS myelin proteome of adult PLP null mice, before the onset of disease. We identified three proteins of the septin family to be reduced in abundance, but the nicotinamide adenine dinucleotide (NAD ϩ)-dependent deacetylase sirtuin 2 (SIRT2) was virtually absent. SIRT2 is expressed throughout the oligodendrocyte lineage, and immunoelectron microscopy revealed its association with myelin. Loss of SIRT2 in PLP null was posttranscriptional, suggesting that PLP/DM20 is required for its transport into the myelin compartment. Because normal SIRT2 activity is controlled by the NAD ϩ /NADH ratio, its function may be coupled to the axo-glial metabolism and the long-term support of axons by oligodendrocytes.
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2014
To investigate the result of child-type micro-sensitive mattress sleep monitor on obstructive sle... more To investigate the result of child-type micro-sensitive mattress sleep monitor on obstructive sleep apnea-hypopnea syndrome in children. The PSG and child-type micro-sensitive mattress sleep monitor were synchronously performed on 58 cases of children with OSAHS. The breathing and sleep metrics were compared. By PSG monitoring, 41 cases were diagnosed as mild OSAHS, 14 cases were moderate and 3 cases were severe. The results of mattress system monitoring showed mild OSAHS in 37 cases, 16 cases of moderate and severe OSAHS in 5 cases. Seven patients diagnosed as mild OSAHS monitored by PSG were classified as moderate by mattress system monitoring; three cases diagnosed as mild OSAHS by mattress system monitoring system were diagnosed as moderate by PSG. Among 14 cases of children diagnosed as moderate by PSG, three cases were diagnosed as mild by mattress system monitor and two cases as severe. Children diagnosed as severe by PSG got the same result by mattress system monitor. Two ki...
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2015
OBJECTIVE To investigate the sleep monitoring feature of the MSMS in elderly patients with OSAHS.... more OBJECTIVE To investigate the sleep monitoring feature of the MSMS in elderly patients with OSAHS. METHOD One hundred and ninety patients diagnosed with OSAHS were divided into elderly group and non elderly group according to age, then the results of MSMS were analyzed. RESULT Majority elderly patients were with mild to moderate OSAHS. The nocturnal mean blood oxygen and the lowest oxygen were higher than non elderly group, coupled with higher percentage of the total oxygen saturation < 90% monitoring time (TS90). There was no significant difference in sleep structure between two groups, but the total sleep time of elderly group is lower than the non elderly group, the difference is statistically significant. CONCLUSION The elderly patients with OSAHS were less severe in nature, but the nocturnal hypoxia last longer in the elderly group. There is no significant difference in the sleep structure between the two groups. But the total sleep time decrease in elderly group. With smalle...
American Journal of Otolaryngology
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2009
This paper aims to demonstrate the maxillary mucosa restoration after operation to the nasal fung... more This paper aims to demonstrate the maxillary mucosa restoration after operation to the nasal fungal sinusitis. Observation by microscopic, transmission electron microscopic and scanning electron microscopic was done to the same parts in the maxillary mucosa 3-4 months before and after the endoscopic sinus surgery in the 24 cases of the nasal fungal sinusitis during 2003-2005. Before the operation, all the cases demonstrated epithelia shedding, proliferation, squamous metaplasia, glandular and fibrous tissue proliferation and lymphocytes infiltration. The microtubule was abnormal and mitochondria diminished, 3-4 months after operation, the cavity was clear and smooth and the epithelia complete. The cilia average increased and the cilia lined in the same direction. The structure of microtubules was clear. The mitochondria was elongated and dense. There was no significant difference in the damage on ultramicrostructure of the maxillary mucosa between the chronic nasal sinusitis and chr...
Journal of Laparoendoscopic & Advanced Surgical Techniques
OBJECTIVE To investigate the clinical application value of enhanced recovery after surgery (ERAS)... more OBJECTIVE To investigate the clinical application value of enhanced recovery after surgery (ERAS) combined with the laparoscopic technique in the radical resection of colorectal cancer. METHODS A total of 200 patients undergoing laparoscopic radical surgery for colorectal cancer from June 2014 to June 2017 were selected and randomly divided into ERAS group (n = 100) and conventional (CON) group (n = 100). The ERAS group adopted enhanced recovery approach after surgery for perioperative treatment, while the CON group adopted a CON approach. The operation time, blood loss, first exhaust time, first defecation time, extubation time, complication rate (incision infection, pneumonia, gastric retention, anastomotic leakage, intestinal obstruction, etc.), scores of visual analog scale (VAS) 1, 3, and 7 days after surgery, and nutritional status (albumin, total protein) 1, 3, and 7 days after surgery were compared and analyzed. RESULTS Compared with the CON group, the ERAS group had significantly shorter first exhaust time, first defecation time, and extubation time (all P < .05). The incidence of overall complications in the ERAS group was less than those in the CON group (P < .05); and albumin and total protein were significantly higher in the ERAS group than in the CON group (both P < .05). CONCLUSIONS ERAS combined with laparoscopic techniques for the treatment of colorectal cancer is a safe and feasible practice. It not only promoted the recovery of gastrointestinal function but also improved the perioperative nutritional status of patients.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Dec 1, 2008
To evaluate the effect of snoring on facial growth in children and the changes after surgery. Obs... more To evaluate the effect of snoring on facial growth in children and the changes after surgery. Observations on facial growth were taken by X-ray 1.5 - 2 years before and after surgery on 40 children snorers aged between 2 - 5 years old, whose tonsils and (or) adenoids were completely removed. The data collected before surgery in the 2 - 3 years old snorers and in the 4 - 5 years old ones were compared with the data from healthy children at the same age respectively. The comparison of data between 21 children snorers aged from 2 - 3 and 17 healthy children of the same ages showed that there was no significant difference in the diameter of pharyngeal cavity at tongue base (PAS), the diameter of nasopharyngeal cavity (UPW-PNS) and the angle between mandibular plane and frankfort horizontal plane (FH-MP) within 2 - 3 years group by statistically (P > 0.05). There is no significance in UPW-PNS and FH-MP angle within 4 - 5 years group by statistics (P > 0.05). Others results is significance in all groups (P < 0.05 or P < 0.01). There was no significant difference in all groups expect Y-axis Angle 1.5 - 2 years after surgery (P > 0.05). Abnormal facial growth was caused by the consistent force from the changed way of breathing due to the increasing narrowness of upper airway obstruction and the long-existing obstructive sleep. Surgery done as soon as possible is helpful to reduce the force caused by the obstruction and helpful to the normal facial growth.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Feb 1, 2012
Chinese Journal of Trauma, 2006
Objective To discuss the surgical outcome and operative technique of the modified trans-petrosal ... more Objective To discuss the surgical outcome and operative technique of the modified trans-petrosal presigmoid approach in treating cases with facial nerve palsy after petral bone fracture trea- ted with facial nerve canal decompression method.Methods A total of 15 cases with facial nerve pal- sy were treated with traumatic facial nerve canal decompression technique with the trans-petrosal presig- mold approach combined with high-dose hormone therapy,whereas 12 cases were treated with traditional Chinese medicine.The clinical data were analysed and compared retrospectively according to House- Brackmann facial nerve grading scale.Results At acute stage,eight(53.3%)out of 15 cases recov- ered to levelⅠ(P＜0.05),with no significant postoperative complications such as CSF leakage. Conclusions This approach is simple and safe and can expose extensively the facial nerve bone canal and effectively alleviate the edemous facial nerve aided by high-dose hormone therapy.Therefore,it is suitable for surgical treatment of acute facial nerve palsy after petral bone fractures.
ACS Applied Materials & Interfaces, Dec 7, 2022
Copper coated Bi 0.5 Sb 1.5 Te 3 powders were prepared through electroless plating with simplifie... more Copper coated Bi 0.5 Sb 1.5 Te 3 powders were prepared through electroless plating with simplified pretreatment method. After hydrogen reduction, the powders are consolidated into bulk by spark plasma sintering. The lowest lattice thermal conductivity in Bi 0.5 Sb 1.5 Te 3 /Cu reduces to 0.25 W/m•K at 371.5 K after annealing. The figure of merit (ZT) of Bi 0.5 Sb 1.5 Te 3 /Cu ascends in a large scale and reaches 1.08 at 373 K and 423 K before and after annealing respectively. The average ZT values of Bi 0.5 Sb 1.5 Te 3 /Cu samples both rise from 0.36 to 0.82, which makes this material suitable for application in a wide temperature range.
Chinese journal of otorhinolaryngology head and neck surgery, Jul 1, 2010
Objective: To evaluate the feasibility of endoscopic surgery using the low-temperature plasma rad... more Objective: To evaluate the feasibility of endoscopic surgery using the low-temperature plasma radiofrequency for nasopharyngeal angiofibroma (NA). Methods: The clinical data of 4 patients treated between December 2005 and August 2009 were retrospectively analyzed. The tumor in one patient was at stage I and three patients were at stage II, all these patients were treated by endoscopic surgery using the low-temperature plasma radiofrequency under controlled hypotension anesthesia. Preoperative angiography and embolisation were underwent in all patients. Bipolar coagulation was used to help hemostasis during operation. Results: The tumor in all 4 patients was completely removed. The operation time was 60, 80, 110, 90 min respectively. The blood loss was 250, 250, 320, 280 ml respectively. Neither blood transfusion nor complications were encountered perioperatively. Follow-up ranged from 6 months to 4 years, none of the patients recurred. Conclusions: Endoscopic surgery using low-temperature plasma radiofrequency for nasopharyngeal angiofibroma has many advantages such as less bleeding and total tumor removal. It is a minimally invasive surgical method for nasopharyngeal angiofibroma.
Studies in Law and Justice
The launch of ChatGPT marks a breakthrough in the development of generative artificial intelligen... more The launch of ChatGPT marks a breakthrough in the development of generative artificial intelligence (generative AI) technology, which is based on the collection and learning of big data as its core operating mechanism. Now the generative AI has the characteristics of high intelligence and high generalization and thus has led to various criminal risks. The current criminal law norms are inadequate in terms of the attribution system and crime norms for the criminal risks caused by the generative AI technologies. Thus, we should clarify the types of risks and governance challenges of generative AI, clarify that data is the object of risk governance, and establish a pluralistic liability allocation mechanism and a mixed legal governance framework of criminal, civil, and administrative law on this basis.
Scripta Materialia, 2016
eAg nanocomposites were fabricated using a chemical plating method and then compacted via spark p... more eAg nanocomposites were fabricated using a chemical plating method and then compacted via spark plasma sintering at 673 K and 50 MPa for 5 min. The effects of TiO 2 eAg nanoparticles (NPs) dispersed into Bi 0.4 Sb 1.6 Te 3 on the thermoelectric and mechanical properties were investigated. The results demonstrated that the carrier concentration and electrical conductivity increased by the incorporation of TiO 2 eAg NPs. Moreover, the addition of TiO 2 eAg NPs also changed the Fermi level positions and the maximum ZT could be obtained in the temperature range of 300-500 K. The maximum ZT value for a Bi 0.4 Sb 1.6 Te 3 /TiO 2 eAg (0.25 wt %) sample was 1.19 at 375 K due primarily to a significant increase in the power factor and an appropriate thermal conductivity. Consequently, the thermoelectric and mechanical properties were improved by embedding the TiO 2 eAg NPs into the Bi 0.4 Sb 1.6 Te 3 matrix.
American Journal of Translational Research, 2022
Frontiers in Cellular Neuroscience, 2020
Myelin membranes are dominated by lipids while the complexity of their protein composition has lo... more Myelin membranes are dominated by lipids while the complexity of their protein composition has long been considered to be low. However, numerous additional myelin proteins have been identified since. Here we revisit the proteome of myelin biochemically purified from the brains of healthy c56Bl/6N-mice utilizing complementary proteomic approaches for deep qualitative and quantitative coverage. By gel-free, label-free mass spectrometry, the most abundant myelin proteins PLP, MBP, CNP, and MOG constitute 38, 30, 5, and 1% of the total myelin protein, respectively. The relative abundance of myelin proteins displays a dynamic range of over four orders of magnitude, implying that PLP and MBP have overshadowed less abundant myelin constituents in initial gel-based approaches. By comparisons with published datasets we evaluate to which degree the CNS myelin proteome correlates with the mRNA and protein abundance profiles of myelin and oligodendrocytes. Notably, the myelin proteome displays only minor changes if assessed after a post-mortem delay of 6 h. These data provide the most comprehensive proteome resource of CNS myelin so far and a basis for addressing proteomic heterogeneity of myelin in mouse models and human patients with white matter disorders.
Oligodendrocytes, 2019
Molecular characterization of myelin is a prerequisite for understanding the normal structure of ... more Molecular characterization of myelin is a prerequisite for understanding the normal structure of the axon/ myelin-unit in the healthy nervous system and abnormalities in myelin-related disorders. However, reliable molecular profiles necessitate very pure myelin membranes, in particular when considering the power of highly sensitive "omics"-data acquisition methods. Here, we recapitulate the history and recent applications of myelin purification. We then provide our laboratory protocols for the biochemical isolation of a highly pure myelin-enriched fraction from mouse brains and for its proteomic analysis. We also supply methodological modifications when investigating posttranslational modifications, RNA, or myelin from peripheral nerves. Notably, technical advancements in solubilizing myelin are beneficial for gel-based and gel-free myelin proteome analyses. We conclude this article by exemplifying the exceptional power of label-free proteomics in the mass-spectrometric quantification of myelin proteins.
Proteomes, Jan 12, 2017
Post-translational modifications (PTMs) play a key role in regulating protein function, yet their... more Post-translational modifications (PTMs) play a key role in regulating protein function, yet their identification is technically demanding. Here, we present a straightforward workflow to systematically identify post-translationally modified proteins based on two-dimensional gel electrophoresis. Upon colloidal Coomassie staining the proteins are partially transferred, and the investigated PTMs are immunodetected. This strategy allows tracking back the immunopositive antigens to the corresponding spots on the original gel, from which they are excised and mass spectrometrically identified. Candidate proteins are validated on the same membrane by immunodetection using a second fluorescence channel. We exemplify the power of partial immunoblotting with the identification of lysine-acetylated proteins in myelin, the oligodendroglial membrane that insulates neuronal axons. The excellent consistency of the detected fluorescence signals at all levels allows the differential comparison of PTMs...
Journal of Neuroscience, 2007
Mice lacking the expression of proteolipid protein (PLP)/DM20 in oligodendrocytes provide a genui... more Mice lacking the expression of proteolipid protein (PLP)/DM20 in oligodendrocytes provide a genuine model for spastic paraplegia (SPG-2). Their axons are well myelinated but exhibit impaired axonal transport and progressive degeneration, which is difficult to attribute to the absence of a single myelin protein. We hypothesized that secondary molecular changes in PLP null myelin contribute to the loss of PLP/DM20-dependent neuroprotection and provide more insight into glia-axonal interactions in this disease model. By gel-based proteome analysis, we identified Ͼ160 proteins in purified myelin membranes, which allowed us to systematically monitor the CNS myelin proteome of adult PLP null mice, before the onset of disease. We identified three proteins of the septin family to be reduced in abundance, but the nicotinamide adenine dinucleotide (NAD ϩ)-dependent deacetylase sirtuin 2 (SIRT2) was virtually absent. SIRT2 is expressed throughout the oligodendrocyte lineage, and immunoelectron microscopy revealed its association with myelin. Loss of SIRT2 in PLP null was posttranscriptional, suggesting that PLP/DM20 is required for its transport into the myelin compartment. Because normal SIRT2 activity is controlled by the NAD ϩ /NADH ratio, its function may be coupled to the axo-glial metabolism and the long-term support of axons by oligodendrocytes.
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2014
To investigate the result of child-type micro-sensitive mattress sleep monitor on obstructive sle... more To investigate the result of child-type micro-sensitive mattress sleep monitor on obstructive sleep apnea-hypopnea syndrome in children. The PSG and child-type micro-sensitive mattress sleep monitor were synchronously performed on 58 cases of children with OSAHS. The breathing and sleep metrics were compared. By PSG monitoring, 41 cases were diagnosed as mild OSAHS, 14 cases were moderate and 3 cases were severe. The results of mattress system monitoring showed mild OSAHS in 37 cases, 16 cases of moderate and severe OSAHS in 5 cases. Seven patients diagnosed as mild OSAHS monitored by PSG were classified as moderate by mattress system monitoring; three cases diagnosed as mild OSAHS by mattress system monitoring system were diagnosed as moderate by PSG. Among 14 cases of children diagnosed as moderate by PSG, three cases were diagnosed as mild by mattress system monitor and two cases as severe. Children diagnosed as severe by PSG got the same result by mattress system monitor. Two ki...
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2015
OBJECTIVE To investigate the sleep monitoring feature of the MSMS in elderly patients with OSAHS.... more OBJECTIVE To investigate the sleep monitoring feature of the MSMS in elderly patients with OSAHS. METHOD One hundred and ninety patients diagnosed with OSAHS were divided into elderly group and non elderly group according to age, then the results of MSMS were analyzed. RESULT Majority elderly patients were with mild to moderate OSAHS. The nocturnal mean blood oxygen and the lowest oxygen were higher than non elderly group, coupled with higher percentage of the total oxygen saturation < 90% monitoring time (TS90). There was no significant difference in sleep structure between two groups, but the total sleep time of elderly group is lower than the non elderly group, the difference is statistically significant. CONCLUSION The elderly patients with OSAHS were less severe in nature, but the nocturnal hypoxia last longer in the elderly group. There is no significant difference in the sleep structure between the two groups. But the total sleep time decrease in elderly group. With smalle...
American Journal of Otolaryngology
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2009
This paper aims to demonstrate the maxillary mucosa restoration after operation to the nasal fung... more This paper aims to demonstrate the maxillary mucosa restoration after operation to the nasal fungal sinusitis. Observation by microscopic, transmission electron microscopic and scanning electron microscopic was done to the same parts in the maxillary mucosa 3-4 months before and after the endoscopic sinus surgery in the 24 cases of the nasal fungal sinusitis during 2003-2005. Before the operation, all the cases demonstrated epithelia shedding, proliferation, squamous metaplasia, glandular and fibrous tissue proliferation and lymphocytes infiltration. The microtubule was abnormal and mitochondria diminished, 3-4 months after operation, the cavity was clear and smooth and the epithelia complete. The cilia average increased and the cilia lined in the same direction. The structure of microtubules was clear. The mitochondria was elongated and dense. There was no significant difference in the damage on ultramicrostructure of the maxillary mucosa between the chronic nasal sinusitis and chr...
Journal of Laparoendoscopic & Advanced Surgical Techniques
OBJECTIVE To investigate the clinical application value of enhanced recovery after surgery (ERAS)... more OBJECTIVE To investigate the clinical application value of enhanced recovery after surgery (ERAS) combined with the laparoscopic technique in the radical resection of colorectal cancer. METHODS A total of 200 patients undergoing laparoscopic radical surgery for colorectal cancer from June 2014 to June 2017 were selected and randomly divided into ERAS group (n = 100) and conventional (CON) group (n = 100). The ERAS group adopted enhanced recovery approach after surgery for perioperative treatment, while the CON group adopted a CON approach. The operation time, blood loss, first exhaust time, first defecation time, extubation time, complication rate (incision infection, pneumonia, gastric retention, anastomotic leakage, intestinal obstruction, etc.), scores of visual analog scale (VAS) 1, 3, and 7 days after surgery, and nutritional status (albumin, total protein) 1, 3, and 7 days after surgery were compared and analyzed. RESULTS Compared with the CON group, the ERAS group had significantly shorter first exhaust time, first defecation time, and extubation time (all P < .05). The incidence of overall complications in the ERAS group was less than those in the CON group (P < .05); and albumin and total protein were significantly higher in the ERAS group than in the CON group (both P < .05). CONCLUSIONS ERAS combined with laparoscopic techniques for the treatment of colorectal cancer is a safe and feasible practice. It not only promoted the recovery of gastrointestinal function but also improved the perioperative nutritional status of patients.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Dec 1, 2008
To evaluate the effect of snoring on facial growth in children and the changes after surgery. Obs... more To evaluate the effect of snoring on facial growth in children and the changes after surgery. Observations on facial growth were taken by X-ray 1.5 - 2 years before and after surgery on 40 children snorers aged between 2 - 5 years old, whose tonsils and (or) adenoids were completely removed. The data collected before surgery in the 2 - 3 years old snorers and in the 4 - 5 years old ones were compared with the data from healthy children at the same age respectively. The comparison of data between 21 children snorers aged from 2 - 3 and 17 healthy children of the same ages showed that there was no significant difference in the diameter of pharyngeal cavity at tongue base (PAS), the diameter of nasopharyngeal cavity (UPW-PNS) and the angle between mandibular plane and frankfort horizontal plane (FH-MP) within 2 - 3 years group by statistically (P > 0.05). There is no significance in UPW-PNS and FH-MP angle within 4 - 5 years group by statistics (P > 0.05). Others results is significance in all groups (P < 0.05 or P < 0.01). There was no significant difference in all groups expect Y-axis Angle 1.5 - 2 years after surgery (P > 0.05). Abnormal facial growth was caused by the consistent force from the changed way of breathing due to the increasing narrowness of upper airway obstruction and the long-existing obstructive sleep. Surgery done as soon as possible is helpful to reduce the force caused by the obstruction and helpful to the normal facial growth.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Feb 1, 2012