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antonio bobbio

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Papers by antonio bobbio

Research paper thumbnail of Case report - Thoracic non-oncologic Endometriosis-related spontaneous diaphragmatic rupture

Non-traumatic, spontaneous diaphragmatic rupture is a rare event whose pathophysiology is not kno... more Non-traumatic, spontaneous diaphragmatic rupture is a rare event whose pathophysiology is not known. We report the case of endometriosis-related spontaneous rupture of the right diaphragm with intrathoracic herniation of the liver, gallbladder and colon. We hypothesize that the invasiveness of endometriotic tissue caused diaphragm fragility, which finally lead to its complete rupture without traumatic event. The treatment consisted of a classical management of diaphragmatic rupture, with excision of the endometriotic nodule followed by medical ovarian suppression for six months. 2010 Published by European Association for Cardio-Thoracic Surgery. All rights reserved.

Research paper thumbnail of Sarcopenia as independent risk factor of postpneumonectomy respiratory failure, ARDS and mortality

Research paper thumbnail of Isolation and preservation of perichondrium during costal resection; positive intraoperative “hooking maneuver” with subluxation of costal cartilage and resection

Research paper thumbnail of Thoracic Endometriosis Syndrome Other Than Pneumothorax: Clinical and Pathological Findings

The Annals of Thoracic Surgery, 2017

Research paper thumbnail of Resection of Superior Sulcus Cancers: Anterior Approach

Atlas of Procedures in Surgical Oncology with Critical, Evidence-Based Commentary Notes, 2009

Research paper thumbnail of Extra-Abdominal Endometriosis

Science and Practice, 2012

Research paper thumbnail of Lobectomy with pulmonary artery resection: Morbidity, mortality, and long-term survival

The Journal of Thoracic and Cardiovascular Surgery, 2009

Research paper thumbnail of Intertumor heterogeneity of non-small-cell lung carcinomas revealed by multiplexed mutation profiling and integrative genomics

International Journal of Cancer, 2014

Research paper thumbnail of Pneumothorax in Women of Child-Bearing Age

Chest, 2014

A significant percentage of pneumothorax in women is due to thoracic endometriosis. Pathophysiolo... more A significant percentage of pneumothorax in women is due to thoracic endometriosis. Pathophysiologic mechanisms continue to be debated, and pathologic aspects are poorly known. Clinical and pathologic records of all consecutive women of reproductive age operated on for pneumothorax between 2000 and 2011 were retrospectively reviewed. Two hundred twenty-nine women (mean age, 33 years) underwent surgery. One hundred forty-four cases (63%) were right-sided, and pneumothoraces were catamenial for 80 women (35%). Diagnosed pelvic endometriosis was associated in 29 cases. At pathology, thoracic endometriosis was diagnosed in 54 cases (24%). Endometrial glands were observed in 33 of 54 cases and were often cystic (16 of 33). Stroma was observed in 51 of 54 cases and endometrial stroma without glands in 21 cases. Hemosiderin-laden macrophages were observed in 27 of 54 cases. All cases of thoracic endometriosis were positive for progesterone and/or estrogen receptors (intense and nuclear). Catamenial pneumothoraces (n = 80, 34.9%) were endometriosis related in 50% of cases (n = 40, 17% of the whole population). Pneumothoraces were noncatamenial but endometriosis related in 6% of cases (n = 14) and merely idiopathic in 60% of patients (n = 135). Multivariate analysis showed that right side, presence of diaphragmatic abnormalities, relapse after unilateral surgery, and presence of hemosiderin-laden macrophages were independent variables associated with thoracic endometriosis (all, P < .02). Apical emphysema-like changes were found in 184 of the 213 patients (86%) with apical resection and were significantly associated with the absence of thoracic endometriosis (P < .001). In women with surgically treated pneumothorax, prevalence of catamenial/endometriosis-related pneumothorax is high. Clinicians and pathologists must be aware to recognize such a difficult diagnosis.

Research paper thumbnail of Pneumothorax Recurrence After Surgery in Women: Clinicopathologic Characteristics and Management

The Annals of Thoracic Surgery, 2011

Research paper thumbnail of Management of postintubation membranous tracheal rupture

The Annals of Thoracic Surgery, 2004

Research paper thumbnail of Case report - Thoracic non-oncologic Endometriosis-related spontaneous diaphragmatic rupture

Non-traumatic, spontaneous diaphragmatic rupture is a rare event whose pathophysiology is not kno... more Non-traumatic, spontaneous diaphragmatic rupture is a rare event whose pathophysiology is not known. We report the case of endometriosis-related spontaneous rupture of the right diaphragm with intrathoracic herniation of the liver, gallbladder and colon. We hypothesize that the invasiveness of endometriotic tissue caused diaphragm fragility, which finally lead to its complete rupture without traumatic event. The treatment consisted of a classical management of diaphragmatic rupture, with excision of the endometriotic nodule followed by medical ovarian suppression for six months. 2010 Published by European Association for Cardio-Thoracic Surgery. All rights reserved.

Research paper thumbnail of Sarcopenia as independent risk factor of postpneumonectomy respiratory failure, ARDS and mortality

Research paper thumbnail of Isolation and preservation of perichondrium during costal resection; positive intraoperative “hooking maneuver” with subluxation of costal cartilage and resection

Research paper thumbnail of Thoracic Endometriosis Syndrome Other Than Pneumothorax: Clinical and Pathological Findings

The Annals of Thoracic Surgery, 2017

Research paper thumbnail of Resection of Superior Sulcus Cancers: Anterior Approach

Atlas of Procedures in Surgical Oncology with Critical, Evidence-Based Commentary Notes, 2009

Research paper thumbnail of Extra-Abdominal Endometriosis

Science and Practice, 2012

Research paper thumbnail of Lobectomy with pulmonary artery resection: Morbidity, mortality, and long-term survival

The Journal of Thoracic and Cardiovascular Surgery, 2009

Research paper thumbnail of Intertumor heterogeneity of non-small-cell lung carcinomas revealed by multiplexed mutation profiling and integrative genomics

International Journal of Cancer, 2014

Research paper thumbnail of Pneumothorax in Women of Child-Bearing Age

Chest, 2014

A significant percentage of pneumothorax in women is due to thoracic endometriosis. Pathophysiolo... more A significant percentage of pneumothorax in women is due to thoracic endometriosis. Pathophysiologic mechanisms continue to be debated, and pathologic aspects are poorly known. Clinical and pathologic records of all consecutive women of reproductive age operated on for pneumothorax between 2000 and 2011 were retrospectively reviewed. Two hundred twenty-nine women (mean age, 33 years) underwent surgery. One hundred forty-four cases (63%) were right-sided, and pneumothoraces were catamenial for 80 women (35%). Diagnosed pelvic endometriosis was associated in 29 cases. At pathology, thoracic endometriosis was diagnosed in 54 cases (24%). Endometrial glands were observed in 33 of 54 cases and were often cystic (16 of 33). Stroma was observed in 51 of 54 cases and endometrial stroma without glands in 21 cases. Hemosiderin-laden macrophages were observed in 27 of 54 cases. All cases of thoracic endometriosis were positive for progesterone and/or estrogen receptors (intense and nuclear). Catamenial pneumothoraces (n = 80, 34.9%) were endometriosis related in 50% of cases (n = 40, 17% of the whole population). Pneumothoraces were noncatamenial but endometriosis related in 6% of cases (n = 14) and merely idiopathic in 60% of patients (n = 135). Multivariate analysis showed that right side, presence of diaphragmatic abnormalities, relapse after unilateral surgery, and presence of hemosiderin-laden macrophages were independent variables associated with thoracic endometriosis (all, P < .02). Apical emphysema-like changes were found in 184 of the 213 patients (86%) with apical resection and were significantly associated with the absence of thoracic endometriosis (P < .001). In women with surgically treated pneumothorax, prevalence of catamenial/endometriosis-related pneumothorax is high. Clinicians and pathologists must be aware to recognize such a difficult diagnosis.

Research paper thumbnail of Pneumothorax Recurrence After Surgery in Women: Clinicopathologic Characteristics and Management

The Annals of Thoracic Surgery, 2011

Research paper thumbnail of Management of postintubation membranous tracheal rupture

The Annals of Thoracic Surgery, 2004

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