bahar bagheri - Academia.edu (original) (raw)
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Royal Holloway, University of London
Università Cattolica del Sacro Cuore (Catholic University of the Sacred Heart)
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Supplemental material, sj-pdf-1-lup-10.1177_0961203320984539 for Electron microscopy study of 496... more Supplemental material, sj-pdf-1-lup-10.1177_0961203320984539 for Electron microscopy study of 496 cases of lupus nephritis: A single-center experience by Bahar Bagheri, Seyed Mohammad Owji, Simin Torabinezhad, Hadi Raeisi Shahraki, Amirhossein Kamalinia, Seyed Hossein Owji and Farshad Dehghani in Lupus
Lupus, 2021
Introduction Renal involvement is seen in about 40-82% of systemic lupus erythematosus (SLE) Asia... more Introduction Renal involvement is seen in about 40-82% of systemic lupus erythematosus (SLE) Asian patients. The exact diagnosis and classification of lupus nephritis are important for treatment and prognosis. This study aimed to investigate the value of electron microscopy (EM) in the diagnosis and classification of lupus nephritis compared with light microscopy. Method In this cross-sectional referral-center 16-year study of lupus nephritis, the final diagnosis was based on the EM study. Primary light microscopy findings were compared with EM diagnosis. Moreover, Immunofluorescence patterns distribution was assessed. Results From 496 patients diagnosed with lupus nephritis based on EM, 225(45.4%) of patients were categorized in class IV, followed by 98(19.7%), 93(18.8%), 46(9.3%), and 14(2.8%) who were categorized into classes of II, III, V, and VI respectively. Only 1(0.2%) patient belonged to class I, and 19(3.8%) cases were diagnosed with mixed two classes. Using EM was essenti...
Journal of Nephropathology
Introduction: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that can involv... more Introduction: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that can involve various organs. Renal involvement has been seen in about 60% of SLE patients, while the most common presentation of lupus nephritis (LN) is proteinuria. Objectives: This study aimed to investigate the clinical and laboratory features of LN patients, confirmed by kidney biopsy and compare these among different classes of LN. Patients and Methods: This cross-sectional study was conducted on clinical and laboratory data of patients with LN from 2001 to 2016. All patients diagnosed with definite LN by biopsy and electron microscopy (EM) were included in this study. Results: A total number of 496 patients were enrolled. The mean age of all patients was 28.32 ±11.41 years; 82.4% (409) were females. The biopsies were classified into LN classes II, III, IV, V, and VI, whose frequencies were 98 (20.6%), 93 (19.5%), 225(47.3%), 46 (9.7%), and 14 (2.9%), respectively. Tubular atrophy (P<0.001)...
Supplemental material, sj-pdf-1-lup-10.1177_0961203320984539 for Electron microscopy study of 496... more Supplemental material, sj-pdf-1-lup-10.1177_0961203320984539 for Electron microscopy study of 496 cases of lupus nephritis: A single-center experience by Bahar Bagheri, Seyed Mohammad Owji, Simin Torabinezhad, Hadi Raeisi Shahraki, Amirhossein Kamalinia, Seyed Hossein Owji and Farshad Dehghani in Lupus
Lupus, 2021
Introduction Renal involvement is seen in about 40-82% of systemic lupus erythematosus (SLE) Asia... more Introduction Renal involvement is seen in about 40-82% of systemic lupus erythematosus (SLE) Asian patients. The exact diagnosis and classification of lupus nephritis are important for treatment and prognosis. This study aimed to investigate the value of electron microscopy (EM) in the diagnosis and classification of lupus nephritis compared with light microscopy. Method In this cross-sectional referral-center 16-year study of lupus nephritis, the final diagnosis was based on the EM study. Primary light microscopy findings were compared with EM diagnosis. Moreover, Immunofluorescence patterns distribution was assessed. Results From 496 patients diagnosed with lupus nephritis based on EM, 225(45.4%) of patients were categorized in class IV, followed by 98(19.7%), 93(18.8%), 46(9.3%), and 14(2.8%) who were categorized into classes of II, III, V, and VI respectively. Only 1(0.2%) patient belonged to class I, and 19(3.8%) cases were diagnosed with mixed two classes. Using EM was essenti...
Journal of Nephropathology
Introduction: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that can involv... more Introduction: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that can involve various organs. Renal involvement has been seen in about 60% of SLE patients, while the most common presentation of lupus nephritis (LN) is proteinuria. Objectives: This study aimed to investigate the clinical and laboratory features of LN patients, confirmed by kidney biopsy and compare these among different classes of LN. Patients and Methods: This cross-sectional study was conducted on clinical and laboratory data of patients with LN from 2001 to 2016. All patients diagnosed with definite LN by biopsy and electron microscopy (EM) were included in this study. Results: A total number of 496 patients were enrolled. The mean age of all patients was 28.32 ±11.41 years; 82.4% (409) were females. The biopsies were classified into LN classes II, III, IV, V, and VI, whose frequencies were 98 (20.6%), 93 (19.5%), 225(47.3%), 46 (9.7%), and 14 (2.9%), respectively. Tubular atrophy (P<0.001)...