Jung huang - Academia.edu (original) (raw)

Papers by Jung huang

Chinese Journal of Chemistry, 2014

Applied Optics, 2007

InGaAs quantum wells and a Bragg mirror structure are grown on a GaAs substrate to simultaneously... more InGaAs quantum wells and a Bragg mirror structure are grown on a GaAs substrate to simultaneously serve as a low-loss saturable absorber and an output coupler for highly efficient Q switching of a diode-pumped Nd:YAG laser operating at 946 nm. With an incident pump power of 9.2 W, the laser produces pulses of 38 ns duration with average pulse energy of as much as 20 J at a pulse repetition rate of 55 kHz.

Tetrahedron Letters, 1996

A new series of conjugated thiophene compounds 1-4 containing methylsulfonyl and phenylsnlfunyl a... more A new series of conjugated thiophene compounds 1-4 containing methylsulfonyl and phenylsnlfunyl acccptors have been synthesized wluch possess efficient second-order optical nonlinearities, lugh thermal stability and good transparency for use as nonlinear optical mat er i al s.

In this annual report, we present our recent research results of the anchoring energetic, molecul... more In this annual report, we present our recent research results of the anchoring energetic, molecular alignment and field-induced re-orientation in a thin LC film on varying polymeric alignment layers. The photo-induced anisotropy on a photo-alignment film can be controlled by varying the exposure of incident linearly-polarized ultraviolet light. The resulting anchoring properties were studied with optical retardance-voltage (RV), optical transmission-voltage (TV) measurements, polarized infrared absorption spectroscopy and Raman scattering spectroscopy. Our results indicate that the surface anchoring energy on a UV-defined layer can be as large as that on a rubbed polymeric surface. In addition, the anchoring energy in a twist nematic cell can not be decomposed into a simple summation of azimuthal and polar anchoring terms. The LC molecules in a twist pi-cell were found to

Journal of Physics: Condensed Matter, 2006

Time-resolved two-dimensional infrared (2D IR) spectroscopy has been applied to analyse an electr... more Time-resolved two-dimensional infrared (2D IR) spectroscopy has been applied to analyse an electro-optic switching ferroelectric liquid crystal (FLC) mixture. The 2D IR correlation technique clearly shows that the Goldstone mode in the SmC* phase is suppressed by an applied electric field. The field-induced reorientation process initiates from intramolecular motions in about 10 µs. The intramolecular motions then propagate from the molecular segments attached to the same molecule to those fragments on other surrounding molecules. During the field-induced switching, the IR dipoles undergo a collective reorientation but with hindered rotation about the molecular long axis.

A sensitive color sensor module is developed to probe the physiological status of the human cardi... more A sensitive color sensor module is developed to probe the physiological status of the human cardiovascular system. Breathing rhythm and heartbeat activity are observed in real time. The skin lightness and skin color expressed in the L*a*b* color coordinate system fluctuate due to changes in blood perfusion according to the rhythm of the heartbeat. Using a Gaussian mixture model, the cardiovascular system is found to fall into three physiological states. The state distribution profiles differ before and after physical exercise. To obtain time-domain information from the color sensor data, we apply the hidden Markov model to retrieve the transition kinetics of the hidden states. Our data suggest that the cardiovascular system mainly resides in two of the three states and makes rare transitions to the third one under resting conditions. We speculate that this rare state may provide flexibility it needs to adapt to different physiological conditions.

Advanced Series in Physical Chemistry

Photonic Fiber and Crystal Devices: Advances in Materials and Innovations in Device Applications II

We present the results of the ab initio calculated electronic properties, first and second harmon... more We present the results of the ab initio calculated electronic properties, first and second harmonic generation for the A II B IV N 2 (A II =Be, Mg; B IV =C, Si, Ge) compounds with chalcopyrite structure performed using the Linear Augmented Slater-Type Orbitals (LASTO) method. The second-order optical susceptibilities as functions of frequency for A II B IV N 2 are also presented. Specifically, we study the relation between the structural properties and the optical responses. Our electronic band structure and density of states (PDOS) analysis reveal that the underestimate bandgaps of these chalcopyrite A II B IV N 2 are wide enough (from4eV to6eV), direct transition and mainly located at Γ-point. Calcultion results show this new category wide-bandgap ternary nitrides has potential applications in optoelectronics.

Infrared and Photoelectronic Imagers and Detector Devices II

A systematic first-principles calculation of the linear and second-order optical susceptibilities... more A systematic first-principles calculation of the linear and second-order optical susceptibilities as functions of frequency for CsGeBr3 is presented. Specifically, we study the relation between the structural properties and the optical responses. Three structural deformation factors, Deltaalpha, dGe, dX are used to express the degree of distortion from the ideal perovskite structure in bond angle, Ge position, and anion position,

Receptors & Clinical Investigation

BMC biophysics, 2016

The first step in many cellular signaling processes occurs at various types of receptors in the p... more The first step in many cellular signaling processes occurs at various types of receptors in the plasma membrane. Membrane cholesterol can alter these signaling pathways of living cells. However, the process in which the interaction of activated receptors is modulated by cholesterol remains unclear. In this study, we measured single-molecule optical trajectories of epidermal growth factor receptors moving in the plasma membranes of two cancerous cell lines and one normal endothelial cell line. A stochastic model was developed and applied to identify critical information from single-molecule trajectories. We discovered that unliganded epidermal growth factor receptors may reside nearby cholesterol-riched regions of the plasma membrane and can move into these lipid domains when subjected to ligand binding. The amount of membrane cholesterol considerably affects the stability of correlated motion of activated epidermal growth factor receptors. Our results provide single-molecule evidenc...

Sensors (Basel, Switzerland), Jan 10, 2017

Cell-penetrating peptides (CPPs) can translocate across cell membranes, and thus have great poten... more Cell-penetrating peptides (CPPs) can translocate across cell membranes, and thus have great potential for the cellular delivery of macromolecular cargoes. However, the mechanism of this cellular uptake process is not yet fully understood. In this study, a time-lapse single-particle light-sheet microscopy technique was implemented to obtain a parallel visualization of the translocating process of individual human immunodeficiency virus 1 (HIV-1) transactivator of transcription (Tat) peptide conjugated quantum dots (TatP-QDs) in complex cellular terrains. Here, TatP-QDs served as nanoscale dynamic pens, which depict remarkable trajectory aggregates of TatP-QDs on the cell surface. Spectral-embedding analysis of the trajectory aggregates revealed a manifold formed by isotropic diffusion and a fraction of directed movement, possibly caused by interaction between the Tat peptides and heparan sulfate groups on the plasma membrane. Further analysis indicated that the membrane deformation i...

We investigate the performance of amorphous Si (a-Si) solar cells fabricated with Inductively Cou... more We investigate the performance of amorphous Si (a-Si) solar cells fabricated with Inductively Coupled Plasma (ICP) deposition technique. The ICP system produces a-Si films with low defect density ð3 Â 10 15 cm À3 Þ, resulting in a conversion efficiency of 9.6%. Deep level transient spectroscopy (DLTS) reveals that hole carriers trapped at defects near the valence band edge delocalize at 130 K; while trapped electrons can only be emitted into the conduction band near room temperature. Spectrally resolved DLTS study further indicates that light soaking enhances the emission rate of the tapped electrons near the conduction band edge while reduces the transition moments from the hole-trapping defect levels to the conduction band. The combined effects and light soaking-induced defects are responsible for the degradation of a thin film solar cell by light soaking.

Bulletin of the American Physical Society, Mar 2, 2015

To faithfully estimate a signal that varies in both space and time, the optimization strategy use... more To faithfully estimate a signal that varies in both space and time, the optimization strategy used by a live cell is to organize a collection of distributed and mobile receptors into a mobile active clustering. However, living eukaryotic cells are highly heterogeneous and stochastically dynamic. It is therefore important to develop an energetic model based on fundamental laws to verify that the underlying processes are energetically favorable. We developed an energetic model based on the generalized Langevin equation and the Cahn-Hilliard equation to simulate the diffusive behaviors of receptor proteins in the plasma membrane with a hierarchical structure of actin corrals, lipid domains, and receptor proteins. Single-molecule tracking data of EGFR acquired on live HeLa cells agrees with the simulation results. We discovered that after ligand binding, EGFR molecules move into lipid nanodomains. The transition rates between different diffusion states of liganded EGFR molecules are regulated by the lipid domains. Our method captures both the sensitivity of single-molecule processes, statistic accuracy of data analysis, and the hierarchical structure of plasma membranes.

Japanese Journal of Applied Physics Pt 1 Regular Papers Short Notes, Jul 15, 1994

Thesis Cornell University 1988 Source Dissertation Abstracts International Volume 48 12 Section B Page 3602, 1988

The Journal of chemical physics, Jan 14, 2015

Ligand-induced receptor dimerization plays a crucial role in the signaling process of living cell... more Ligand-induced receptor dimerization plays a crucial role in the signaling process of living cells. In this study, we developed a theoretical model and performed single-molecule tracking to explore the correlated diffusion processes of liganded epidermal growth factor receptors prior to dimer formation. We disclosed that both an attractive potential between liganded receptor proteins in proximity and correlated fluctuations in the local environments of the proteins play an important role to produce the observed correlated movement of the receptors. This result can serve as the foundation to shed light on the way in which receptor functions are regulated in plasma membranes in vivo.