kamel boukef - Academia.edu (original) (raw)
Papers by kamel boukef
Revue Des Regions Arides, 2007
The first aim of this study was to describe in detail the chemical composition of Tunisian Mentha... more The first aim of this study was to describe in detail the chemical composition of Tunisian Mentha pulegium L. essential oils (EOs) from Monastir. The second aim was to test their antibacterial activity. The essential oils obtained from fresh and dried aerial parts were analysed by using gas chromatography and mass spectrometry (GC-MS). The antimicrobial activity was evaluated against reference strains: Gram-positive as Enterococcus faecalis. Staphylococcus aureus and Micrococcus luteus and Gram-negative represented by Escherichia coli and Pseudomonas aeruginosa All the EOs are dissolved in tween 80. The minimum inhibitory concentrations (MIC) and the minimum bactericidal concentrations (MBC) were determinated by sub-culture at TSA agar plates which were incubated at 3 7°C during 18-24h. Thirty four compounds were identified. All oils were found to be rich in oxygen monoterpens hydrocarbons especially menthol, menthone, 1,8-cineole and pulegone. These oils have a good antimicrobial activity against all bacteria tested; Enterocoque feacalis is the most sensitive.
The influence of the vegetation and inter-organ and intra-organ stage on the solasodine content w... more The influence of the vegetation and inter-organ and intra-organ stage on the solasodine content was investigated in four natural populations of Solanum sodomeum L. growing in Tunisia. The influence of cutting leaves during immature fruits on the level of the active compound and the effect of ripe fruit number per cym on the percentage of solasodine were studied. The solasodine content increased with the plant age and was higher in the leaves than in stems and roots. The solasodine content varied with the position of leaves, being highest in the basic leaves at full flowering and the beginning of fructification. The solasodine content decreased significantly in the ripe berries when leaves were cut during the immature fruit stage. The content in ripe fruits was highest when the cym consisted of 2-3 berries. The pericarp and the placentary tissues of ripe berries contained more solasodine than the seeds. The solasodine content depended on the geographical site of the four populations.
La Tunisie médicale, 2000
La Tunisie médicale, 1999
Journal de pharmacie de Belgique
Among the neutrophil polynuclear specific antigens (NA, NB, ND, NE, ...), NA antigen is the most ... more Among the neutrophil polynuclear specific antigens (NA, NB, ND, NE, ...), NA antigen is the most common. It is a glycoprotein situated on the neutrophils FcRIIIb-receptor and presents 2 forms: NA1 and NA2. The epitope responsible of that polymorphism has got an amino acids composition that is unknown. The first techniques used for their analysis were the microagglutination and the granulocytotoxicity-later, the immunofluorescence, the chemiluminescence and the MAIGA (Monoclonal Antibody Immobilized granulocyte Antigen) were introduced. These last years, more efficient techniques appeared like Flow Cytometry and Polymerase Chain Reaction (PCR) that allowed phenotyping and genotyping of neutrophil polymorphonuclear specific antigens. The studies indicated that NA antigen frequency varies according to the populations and the ethnics. NA2 allelic form is more frequent than NA1 in the caucasian population (88% VS 46%). In human pathology, NA antigen is implicated in the physiopathologica...
Annales pharmaceutiques françaises, 1988
Transfusion Clinique et Biologique, 1995
disequilibrium was found for the following allelic associations : All B35 (X 2 = 6.8), A28 B35 (X... more disequilibrium was found for the following allelic associations : All B35 (X 2 = 6.8), A28 B35 (X 2 = 5.3), and A30 B35 (X 2 = 5). In conclusion, a specific distribution of HLA class I components in terms of antigen and haplotype frequencies characterizes the Tunisian population. This specific pattern may reflect the great ethnical diversity of this community. All these informations may be hepful in the future for HLA and disease association studies.
Journal of Biologically Active Products from Nature, 2012
Abstract This study investigates the in vivo analgesic and anti-inflammatory activities of variou... more Abstract This study investigates the in vivo analgesic and anti-inflammatory activities of various extracts prepared from Apium graveolens. This activity was evaluated with the acetic acid-induced writhing response method. The subcutaneous carrageenan injection induced hind paw edema. The treated animals received different doses of either aqueous or organic extracts, the reference group received ketoprofen or piroxicam and the control group received NaCl 0.9 %. The volume of the left and right legs was measured with a plethysmometer. A statistical analysis was performed by the Student t test. All extracts showed a significant reduction in the acetic acid-induced writhing test (63 %), compared with the reference group (53 %) (P<0.001). The aqueous extracts of A. graveolens showed a significant inhibition of edema (69 % – 73 %) (p <0.01). The methanol extract also induced a significant inhibition (70 %). These results were similar to those obtained with piroxicam (70 %) but higher than those obtained with ketoprofen (55 %).
Journal of Biologically Active Products from Nature, 2011
Abstract The methanol and acetone extracts prepared from Apium graveolens were tested to determin... more Abstract The methanol and acetone extracts prepared from Apium graveolens were tested to determine their antioxidant activities by using the ferric reducing antioxidant power (FRAP), the iron chelation activity, the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) scavenging activity and the superoxide radical scavenging activity. The contents of total phenolic compounds in the two extracts were measured using a Folin-Ciocalteu assay. As a result, methanol showed the best antioxidant effect in comparison with acetone extract. Superoxide scavenging activity in A. graveolens rose above 80% at 1000 mg/ml for both acetone and methanol extracts. The FRAP was more important with methanol extract (65%) compared with that of acetone extract (40%). The dosage of the polyphenolic components showed that phenol acids, tannins and flavonoids concentrations were higher in methanol extract than in acetone extract.
Revue Française de Transfusion et d'Hémobiologie, 1993
ABSTRACT La présente étude a porté sur 4 129 donneurs de sang provenant de différentes régions de... more ABSTRACT La présente étude a porté sur 4 129 donneurs de sang provenant de différentes régions de Tunisie. Elle nous a permis de déterminer les fréquences géniques dans le système Rhésus. Les fréquences retrouvées pour les différents haplotypes sont les suivantes:
Revue Française de Transfusion et d'Hémobiologie, 1991
ABSTRACT A study carried out on 2 006 Tunisian blood donors permitted us to evaluate the prevalen... more ABSTRACT A study carried out on 2 006 Tunisian blood donors permitted us to evaluate the prevalence of hepatitis C virus antibodies (anti-HCV) which was 1.09%; frequency of indirect markers of NANBH were as follows: ALAT > 2 N (1.24%), anti-HBc (30.35%), 55.5% of HCV (+) donors had anti-HBc (+), 12.5% had rises ALAT and only 33,3% both markers.
Transfusion Clinique et Biologique, 1998
Session 29-Posters libres 225S ture de Plasmodium falciparum (facult6 de m6decine de Lille, servi... more Session 29-Posters libres 225S ture de Plasmodium falciparum (facult6 de m6decine de Lille, service de parasitologie). Les s6rums sont d ilu6s au 1 /100L Le conjugu6 est un anti-GAM ;
Transfusion Clinique et Biologique, 1994
La pr6sente 6rude a port6 sur 18 820 donneurs de sang provenant de diff6rentes r6gions de Tunisie... more La pr6sente 6rude a port6 sur 18 820 donneurs de sang provenant de diff6rentes r6gions de Tunisie. Elle nous a permis de d6terminer les fr6quences g6niques des all61es du syst6me ABO. Les fr6quences retrouv6es sont les suivantes : A(0,192), B(0,122), 0(0,686).
Tissue Antigens, 1995
Tunisian population-HLA polymorphism-DNA typingallele and haplotype frequencieslinkage disequilib... more Tunisian population-HLA polymorphism-DNA typingallele and haplotype frequencieslinkage disequilibrium-PCR and reverse dot blot
PLoS Medicine, 2012
The Essay section contains opinion pieces on topics of broad interest to a general medical audience.
Pathologie Biologie, 2001
Le diabète type 1 est une maladie autoimmune, polygénique et multifactorielle. Son association av... more Le diabète type 1 est une maladie autoimmune, polygénique et multifactorielle. Son association avec certains allèles HLA classe II n'explique pas à elle seule le développement de la maladie. D'autre facteurs génétiques interviennent certainement dans la susceptibilité à cette maladie. Le gène CTLA-4 situé sur le chromosome 2q33 (IDDM12) est un bon candidat en raison de son rôle dans la régulation négative de l'activation lymphocytaire T. Dans le présent travail, nous avons abordé le dimorphisme de l'exon 1 du gène CTLA-4 (position 49 A/G), chez 74 diabétiques type 1 et 48 témoins, tous originaires de Tunisie en utilisant deux méthodes de biologie moléculaire PCR RFLP et PCR allèle spécifique. L'allèle CTLA-4/G a été retrouvé plus fréquemment chez les patients diabétiques que chez le témoin (68,92 contre 51,02 % et un p = 0,002). Cet allèle est principalement présent à l'état homozygote (G/G) (43,24 % contre 22,45 avec un p = 0,0058). Ces résultats indiquent que le dimorphisme A/G en position 49 de l'exon 1 du gène CTLA-4 est significativement associé au diabète type 1 dans la population tunisienne. 2001 Éditions scientifiques et médicales Elsevier SAS association-dimorphisme du gène CTLA-4 / diabète type 1 Summary-Association between type 1 diabetes mellitus with cytotoxic T lymphocyte associated 4 (CTLA-4) in tunisian population. Susceptibility to type 1 diabetes mellitus is strongly associated with particular HLA class II alleles. However, non HLA genetic factors are likely to be required for the development of disease. The candidate genes include the cytotoxic T lymphocyte associated 4 (CTLA-4) located on chromosome 2q33 and designated (IDDM12), which encodes a cell surface negative signal T molecule providing for activation. We investigated CTLA-4 exon 1 dimorphism in 74 type 1 patients and a control group of 48 healthy subjects from Tunisia using two methods PCR (polymerase chain reaction) allele specific and polymerase chain reaction restriction fragment length polymorphism (PCR RFLP). The CTLA-4/G allele was found on 68.9% in type 1 patients as compared to 51.02% in controls (p = 0.002), mostly in homozygous from 43.24% versus 22.45% (p = 0.0058). This results indicate that CTLA-4/G allele was significantly associated with predisposition to type 1 diabetes in our group from Tunisian population. 2001 Éditions scientifiques et médicales Elsevier SAS association CTLA-4 gene dimorphism / type 1 diabetes * Correspondance et tirés à part.
Natural Product Research, 2013
This study investigates the antiulcerogenic and antibacterial activities of Apium graveolens extr... more This study investigates the antiulcerogenic and antibacterial activities of Apium graveolens extracts. The antiulcerogenic activity was evaluated in rats by the HCl/EtOH method. Inhibition of gastric lesions by A. graveolens extracts was dose-dependent for both aerial part (53-76%) and seeds (51-95%). The methanolic extract as well as the aqueous extracts used at 300 mg kg(-1) dose exhibited a highly significant inhibition of gastric lesions (91% and 95%, respectively) which was similar to that induced by omeprazole (94%). Essential oil and aqueous extract prepared from the aerial parts of A. graveolens were tested to determine their antibacterial activity using the paper disc-diffusion method, the minimal inhibitory concentration and the minimal bactericidal concentration. Essential oil of A. graveolens was strongly inhibitory against Escherichia coli and moderately inhibitory against Pseudomonas aeruginosa and Staphylococcus aureus. The chemical composition of the volatile oil was investigated by gas chromatography analysis. The major components identified were β-pinene, camphene, cumene, limonene, α-thuyene, α-pinene, β-phellendrene, p-cymene, γ-terpinene, sabinene and terpinolene.
Human Heredity, 1981
Bf and C3 type determinations have been performed in a population from Tunisia. The corresponding... more Bf and C3 type determinations have been performed in a population from Tunisia. The corresponding allele frequencies are as follows: BfsS = 0.6173, BfF = 0.2813, BfS0.7 = 0.0827, BfF1 = 0.0187 and C3S = 0.8326, C3F = 0.1524, C3S0.4 = 0.0086, C3‘F rare’ = 0.0064. According to these values, the Tunisian population seems to be situated between Caucasoid and Negroid populations.Copyright © 1981 S. Karger AG, Basel
Food Chemistry, 1987
Phenolic acids have been determined in the Tunisian currant palm tree products, dates and legmi (... more Phenolic acids have been determined in the Tunisian currant palm tree products, dates and legmi (a fermented sap extract). Reversed phase high performance liquid chromatography has been used and results confirmed for the more concentrated compounds by thin-layer chromatography on silica gel. Gallic acid, protocatechuic, p-hydroxybenzoic, syringic, vanillic, caffeic, pcoumaric and ferulic acids have been identified and the origin of these compounds is discussed. The analysed palm tree products are rich in phenolic acids and are characterized by a high concentration in one particular phenolic acid: ferulic acid for dates, gallic acid for legmi.
Revue Des Regions Arides, 2007
The first aim of this study was to describe in detail the chemical composition of Tunisian Mentha... more The first aim of this study was to describe in detail the chemical composition of Tunisian Mentha pulegium L. essential oils (EOs) from Monastir. The second aim was to test their antibacterial activity. The essential oils obtained from fresh and dried aerial parts were analysed by using gas chromatography and mass spectrometry (GC-MS). The antimicrobial activity was evaluated against reference strains: Gram-positive as Enterococcus faecalis. Staphylococcus aureus and Micrococcus luteus and Gram-negative represented by Escherichia coli and Pseudomonas aeruginosa All the EOs are dissolved in tween 80. The minimum inhibitory concentrations (MIC) and the minimum bactericidal concentrations (MBC) were determinated by sub-culture at TSA agar plates which were incubated at 3 7°C during 18-24h. Thirty four compounds were identified. All oils were found to be rich in oxygen monoterpens hydrocarbons especially menthol, menthone, 1,8-cineole and pulegone. These oils have a good antimicrobial activity against all bacteria tested; Enterocoque feacalis is the most sensitive.
The influence of the vegetation and inter-organ and intra-organ stage on the solasodine content w... more The influence of the vegetation and inter-organ and intra-organ stage on the solasodine content was investigated in four natural populations of Solanum sodomeum L. growing in Tunisia. The influence of cutting leaves during immature fruits on the level of the active compound and the effect of ripe fruit number per cym on the percentage of solasodine were studied. The solasodine content increased with the plant age and was higher in the leaves than in stems and roots. The solasodine content varied with the position of leaves, being highest in the basic leaves at full flowering and the beginning of fructification. The solasodine content decreased significantly in the ripe berries when leaves were cut during the immature fruit stage. The content in ripe fruits was highest when the cym consisted of 2-3 berries. The pericarp and the placentary tissues of ripe berries contained more solasodine than the seeds. The solasodine content depended on the geographical site of the four populations.
La Tunisie médicale, 2000
La Tunisie médicale, 1999
Journal de pharmacie de Belgique
Among the neutrophil polynuclear specific antigens (NA, NB, ND, NE, ...), NA antigen is the most ... more Among the neutrophil polynuclear specific antigens (NA, NB, ND, NE, ...), NA antigen is the most common. It is a glycoprotein situated on the neutrophils FcRIIIb-receptor and presents 2 forms: NA1 and NA2. The epitope responsible of that polymorphism has got an amino acids composition that is unknown. The first techniques used for their analysis were the microagglutination and the granulocytotoxicity-later, the immunofluorescence, the chemiluminescence and the MAIGA (Monoclonal Antibody Immobilized granulocyte Antigen) were introduced. These last years, more efficient techniques appeared like Flow Cytometry and Polymerase Chain Reaction (PCR) that allowed phenotyping and genotyping of neutrophil polymorphonuclear specific antigens. The studies indicated that NA antigen frequency varies according to the populations and the ethnics. NA2 allelic form is more frequent than NA1 in the caucasian population (88% VS 46%). In human pathology, NA antigen is implicated in the physiopathologica...
Annales pharmaceutiques françaises, 1988
Transfusion Clinique et Biologique, 1995
disequilibrium was found for the following allelic associations : All B35 (X 2 = 6.8), A28 B35 (X... more disequilibrium was found for the following allelic associations : All B35 (X 2 = 6.8), A28 B35 (X 2 = 5.3), and A30 B35 (X 2 = 5). In conclusion, a specific distribution of HLA class I components in terms of antigen and haplotype frequencies characterizes the Tunisian population. This specific pattern may reflect the great ethnical diversity of this community. All these informations may be hepful in the future for HLA and disease association studies.
Journal of Biologically Active Products from Nature, 2012
Abstract This study investigates the in vivo analgesic and anti-inflammatory activities of variou... more Abstract This study investigates the in vivo analgesic and anti-inflammatory activities of various extracts prepared from Apium graveolens. This activity was evaluated with the acetic acid-induced writhing response method. The subcutaneous carrageenan injection induced hind paw edema. The treated animals received different doses of either aqueous or organic extracts, the reference group received ketoprofen or piroxicam and the control group received NaCl 0.9 %. The volume of the left and right legs was measured with a plethysmometer. A statistical analysis was performed by the Student t test. All extracts showed a significant reduction in the acetic acid-induced writhing test (63 %), compared with the reference group (53 %) (P<0.001). The aqueous extracts of A. graveolens showed a significant inhibition of edema (69 % – 73 %) (p <0.01). The methanol extract also induced a significant inhibition (70 %). These results were similar to those obtained with piroxicam (70 %) but higher than those obtained with ketoprofen (55 %).
Journal of Biologically Active Products from Nature, 2011
Abstract The methanol and acetone extracts prepared from Apium graveolens were tested to determin... more Abstract The methanol and acetone extracts prepared from Apium graveolens were tested to determine their antioxidant activities by using the ferric reducing antioxidant power (FRAP), the iron chelation activity, the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) scavenging activity and the superoxide radical scavenging activity. The contents of total phenolic compounds in the two extracts were measured using a Folin-Ciocalteu assay. As a result, methanol showed the best antioxidant effect in comparison with acetone extract. Superoxide scavenging activity in A. graveolens rose above 80% at 1000 mg/ml for both acetone and methanol extracts. The FRAP was more important with methanol extract (65%) compared with that of acetone extract (40%). The dosage of the polyphenolic components showed that phenol acids, tannins and flavonoids concentrations were higher in methanol extract than in acetone extract.
Revue Française de Transfusion et d'Hémobiologie, 1993
ABSTRACT La présente étude a porté sur 4 129 donneurs de sang provenant de différentes régions de... more ABSTRACT La présente étude a porté sur 4 129 donneurs de sang provenant de différentes régions de Tunisie. Elle nous a permis de déterminer les fréquences géniques dans le système Rhésus. Les fréquences retrouvées pour les différents haplotypes sont les suivantes:
Revue Française de Transfusion et d'Hémobiologie, 1991
ABSTRACT A study carried out on 2 006 Tunisian blood donors permitted us to evaluate the prevalen... more ABSTRACT A study carried out on 2 006 Tunisian blood donors permitted us to evaluate the prevalence of hepatitis C virus antibodies (anti-HCV) which was 1.09%; frequency of indirect markers of NANBH were as follows: ALAT > 2 N (1.24%), anti-HBc (30.35%), 55.5% of HCV (+) donors had anti-HBc (+), 12.5% had rises ALAT and only 33,3% both markers.
Transfusion Clinique et Biologique, 1998
Session 29-Posters libres 225S ture de Plasmodium falciparum (facult6 de m6decine de Lille, servi... more Session 29-Posters libres 225S ture de Plasmodium falciparum (facult6 de m6decine de Lille, service de parasitologie). Les s6rums sont d ilu6s au 1 /100L Le conjugu6 est un anti-GAM ;
Transfusion Clinique et Biologique, 1994
La pr6sente 6rude a port6 sur 18 820 donneurs de sang provenant de diff6rentes r6gions de Tunisie... more La pr6sente 6rude a port6 sur 18 820 donneurs de sang provenant de diff6rentes r6gions de Tunisie. Elle nous a permis de d6terminer les fr6quences g6niques des all61es du syst6me ABO. Les fr6quences retrouv6es sont les suivantes : A(0,192), B(0,122), 0(0,686).
Tissue Antigens, 1995
Tunisian population-HLA polymorphism-DNA typingallele and haplotype frequencieslinkage disequilib... more Tunisian population-HLA polymorphism-DNA typingallele and haplotype frequencieslinkage disequilibrium-PCR and reverse dot blot
PLoS Medicine, 2012
The Essay section contains opinion pieces on topics of broad interest to a general medical audience.
Pathologie Biologie, 2001
Le diabète type 1 est une maladie autoimmune, polygénique et multifactorielle. Son association av... more Le diabète type 1 est une maladie autoimmune, polygénique et multifactorielle. Son association avec certains allèles HLA classe II n'explique pas à elle seule le développement de la maladie. D'autre facteurs génétiques interviennent certainement dans la susceptibilité à cette maladie. Le gène CTLA-4 situé sur le chromosome 2q33 (IDDM12) est un bon candidat en raison de son rôle dans la régulation négative de l'activation lymphocytaire T. Dans le présent travail, nous avons abordé le dimorphisme de l'exon 1 du gène CTLA-4 (position 49 A/G), chez 74 diabétiques type 1 et 48 témoins, tous originaires de Tunisie en utilisant deux méthodes de biologie moléculaire PCR RFLP et PCR allèle spécifique. L'allèle CTLA-4/G a été retrouvé plus fréquemment chez les patients diabétiques que chez le témoin (68,92 contre 51,02 % et un p = 0,002). Cet allèle est principalement présent à l'état homozygote (G/G) (43,24 % contre 22,45 avec un p = 0,0058). Ces résultats indiquent que le dimorphisme A/G en position 49 de l'exon 1 du gène CTLA-4 est significativement associé au diabète type 1 dans la population tunisienne. 2001 Éditions scientifiques et médicales Elsevier SAS association-dimorphisme du gène CTLA-4 / diabète type 1 Summary-Association between type 1 diabetes mellitus with cytotoxic T lymphocyte associated 4 (CTLA-4) in tunisian population. Susceptibility to type 1 diabetes mellitus is strongly associated with particular HLA class II alleles. However, non HLA genetic factors are likely to be required for the development of disease. The candidate genes include the cytotoxic T lymphocyte associated 4 (CTLA-4) located on chromosome 2q33 and designated (IDDM12), which encodes a cell surface negative signal T molecule providing for activation. We investigated CTLA-4 exon 1 dimorphism in 74 type 1 patients and a control group of 48 healthy subjects from Tunisia using two methods PCR (polymerase chain reaction) allele specific and polymerase chain reaction restriction fragment length polymorphism (PCR RFLP). The CTLA-4/G allele was found on 68.9% in type 1 patients as compared to 51.02% in controls (p = 0.002), mostly in homozygous from 43.24% versus 22.45% (p = 0.0058). This results indicate that CTLA-4/G allele was significantly associated with predisposition to type 1 diabetes in our group from Tunisian population. 2001 Éditions scientifiques et médicales Elsevier SAS association CTLA-4 gene dimorphism / type 1 diabetes * Correspondance et tirés à part.
Natural Product Research, 2013
This study investigates the antiulcerogenic and antibacterial activities of Apium graveolens extr... more This study investigates the antiulcerogenic and antibacterial activities of Apium graveolens extracts. The antiulcerogenic activity was evaluated in rats by the HCl/EtOH method. Inhibition of gastric lesions by A. graveolens extracts was dose-dependent for both aerial part (53-76%) and seeds (51-95%). The methanolic extract as well as the aqueous extracts used at 300 mg kg(-1) dose exhibited a highly significant inhibition of gastric lesions (91% and 95%, respectively) which was similar to that induced by omeprazole (94%). Essential oil and aqueous extract prepared from the aerial parts of A. graveolens were tested to determine their antibacterial activity using the paper disc-diffusion method, the minimal inhibitory concentration and the minimal bactericidal concentration. Essential oil of A. graveolens was strongly inhibitory against Escherichia coli and moderately inhibitory against Pseudomonas aeruginosa and Staphylococcus aureus. The chemical composition of the volatile oil was investigated by gas chromatography analysis. The major components identified were β-pinene, camphene, cumene, limonene, α-thuyene, α-pinene, β-phellendrene, p-cymene, γ-terpinene, sabinene and terpinolene.
Human Heredity, 1981
Bf and C3 type determinations have been performed in a population from Tunisia. The corresponding... more Bf and C3 type determinations have been performed in a population from Tunisia. The corresponding allele frequencies are as follows: BfsS = 0.6173, BfF = 0.2813, BfS0.7 = 0.0827, BfF1 = 0.0187 and C3S = 0.8326, C3F = 0.1524, C3S0.4 = 0.0086, C3‘F rare’ = 0.0064. According to these values, the Tunisian population seems to be situated between Caucasoid and Negroid populations.Copyright © 1981 S. Karger AG, Basel
Food Chemistry, 1987
Phenolic acids have been determined in the Tunisian currant palm tree products, dates and legmi (... more Phenolic acids have been determined in the Tunisian currant palm tree products, dates and legmi (a fermented sap extract). Reversed phase high performance liquid chromatography has been used and results confirmed for the more concentrated compounds by thin-layer chromatography on silica gel. Gallic acid, protocatechuic, p-hydroxybenzoic, syringic, vanillic, caffeic, pcoumaric and ferulic acids have been identified and the origin of these compounds is discussed. The analysed palm tree products are rich in phenolic acids and are characterized by a high concentration in one particular phenolic acid: ferulic acid for dates, gallic acid for legmi.