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Papers by mohammad goli

Research paper thumbnail of Study on the Effect of Replacing Cinnamon with Cardamom and Animal Butter with Plant Butter on Physicochemical Properties of Sohan-Polki

Food Science and Technology, 2020

Research paper thumbnail of Survey on the Effect of Sucrose Replacement with Stevia (Stevia rebaudiana) Powder and Tragacanth Gum on Physico-chemical, Rheological and Sensorial Properties of Apricot Nectar

Pizhūhish va Nuāvarī dar ̒Ulūm va Sanāyi̒-i Ghaz̠āyī, 2018

Awareness of people about the suitable nutrition, can influence human nutrition and lead manufact... more Awareness of people about the suitable nutrition, can influence human nutrition and lead manufacturers to produce food products with low fat, sugar and salt, but with high fiber. One of the special diets is production of low-calorie foods with less sugar. In this study the effect of replacing sucrose with stevioside (0, 50 and 100%) and tragacanth gum (0.5%) in low-calorie apricot nectar was investigated. In the present study the tests included acidity, pH, total solids, total sugar, density, antioxidant activity (DPPH), total phenol, viscosity, lightness and sensory evaluation. The results showed that the Stevia addition had no significant effect on acidity and pH; however, it caused significant changes in the total solids and density of treatments. Total sugar and viscosity reduced with increasing Stevia addition. Antioxidant activity of samples increased with Stevia addition and, in all samples these factors improved through the addition of tragacanth gum. Additionally, rheologic...

Research paper thumbnail of Optimization of dietary Sohan formulation for celiac and diabetic patients by replacing sucrose with isomalt and complete replacing of wheat flour with soybean meal and corn flour by response surface methodology

Food Science and Technology, 2021

Research paper thumbnail of Evaluation of antioxidant properties of sodium-selenite microencapsulated in antioxidant-free soybean oil refined

Food Science and Technology, 2021

Research paper thumbnail of The Effect of Spray Dryer Atomizer Speed on Casein Micelle Size and Physicochemical Properties of White Cheese

In this research, an industrial spray dryer was used and the effects of atomizer speed on the phy... more In this research, an industrial spray dryer was used and the effects of atomizer speed on the physicochemical properties of milk powder, the textural and sensory characteristics of white cheese made from this milk powder were evaluated. For this purpose, whole milk was converted into powder by using three different speeds (10,000, 11,000, and 12,000 rpm). The results showed that by increasing atomizer speed in the spray dryer, the average size of casein micelle is significantly decreased (P < 0.05), whereas no significant effect is observed on the chemical properties of milk powder. White cheese characteristics indicated that by increasing atomizer speed, texture parameters, such as hardness, mastication, and gumminess were significantly reduced (P < 0.05). Sensory evaluation also revealed that the cheese samples prepared with dried milk produced at 12,000 rpm were highly accepted by the panelists. Overall, the findings suggested that 12,000 rpm is the optimal atomizer speed f...

Research paper thumbnail of Investigation of sugar and fat substitution with malt extract and inulin in order to prepare dietary syrup used for probiotic ice cream

Food Science and Technology, 2021

Research paper thumbnail of Physico-chemical characteristics and antioxidant activity of honey containing added Dill extract in the process and biological methods

Food Science and Technology International, 2019

Research paper thumbnail of MPC-based Lateral Controller with Look-Ahead Design for Autonomous Multi-vehicle Merging into Platoon

2019 American Control Conference (ACC), 2019

In this paper a Model Predictive Control (MPC)-based approach is implemented to control the later... more In this paper a Model Predictive Control (MPC)-based approach is implemented to control the lateral maneuver of nonlinear vehicle dynamics. The controller is then applied to a multi-vehicle merging strategy for several vehicles to autonomously merge into a platoon using a variable-gap lateral reference trajectory. The MPC controller features a look-ahead design so that the controller could take actions in advance and thus improve the tracking objective. A combination of constraints, and slack variables-which quantify constraints violation-are chosen to guarantee a safe, efficient, and comfortable ride. The performance of the linear MPC controller is evaluated against a nonlinear plant to demonstrate a more realistic scenario.

Research paper thumbnail of Optimization of cupcake formulation by replacement of wheat flour with different levels of eggplant fiber using response surface methodology

Food Science and Technology, 2021

This study aimed to design and produce optimal formula of cupcakes containing eggplant fiber by s... more This study aimed to design and produce optimal formula of cupcakes containing eggplant fiber by surface response methodology (RSM). The wheat flour replaced with eggplant fiber in five levels, 0-40%, whole-egg and sugar were set at the same time, 55-75% and 70-90% based on (wheat-flour + eggplant-fiber) weight, respectively. Considering the most important textural properties (hardness, cohesiveness, springiness, gumminess and chewiness), density, weight, and also by mean comparisons with Duncan's test at the level of 5% significance, optimal formulas include: formula (a) (12% eggplant-fiber, 71% whole-egg, 70% sugar) and formula (b): (8% eggplant-fiber, 57% whole-egg, 70% sugar) were appropriately suggested. Chemical properties of the optimal formulas including, protein, fat, carbohydrate, moisture, insoluble ash in acid and calorie were calculated and compared with the blank. Using of the eggplant-fiber in cupcake formulation caused calorie reduction and increased its nutritional value. Formula (b), in terms of many factors, demonstrated similarity to the blank. The eggplant-fiber had an impact on all of the textural properties except springiness. The impacts of whole-egg content on springiness, chewiness and density are also remarkable. Sugar content will be shown in weight differences and is expressed as one of the most effective variables on sample weight.

Research paper thumbnail of Optimization of hydrolysis conditions (temperature, time, and concentration of alkalase) of rainbow trout viscera using the response surface methodology

Journal of Food Processing and Preservation, 2021

Research paper thumbnail of Migration of Various Nanoparticles into Food Samples: A Review

Foods, 2021

Nanotechnology has provided new opportunities for the food industry with its applications in food... more Nanotechnology has provided new opportunities for the food industry with its applications in food packaging. The addition of nanoparticles, such as clay, silver and copper, can improve the mechanical and antimicrobial properties of food packaging. However, nanoparticles may have an adverse impact on human health. This has led to legislative and regulatory concerns. The inhibitory effects of nano packaging on different microorganisms, such as Salmonella, E. coli, and molds, have been studied. Nanoparticles, like other materials, may have a diverse set of properties that need to be determined. In this review, different features of silver, clay and copper nanoparticles, such as their anti-microbial, cell toxicity, genetic toxicity, mechanical properties, and migration, are critically evaluated in the case of food packaging. Specifically, the viewpoints of WHO, FDA, and ESFA, concerning the nano-silver application in food packaging, are discussed as well.

Research paper thumbnail of Predisposing factors of important invasive fungal coinfections in COVID-19 patients: a review article

Journal of International Medical Research, 2021

Severe acute respiratory syndrome coronavirus-2 has caused a devastating pandemic lasting for mor... more Severe acute respiratory syndrome coronavirus-2 has caused a devastating pandemic lasting for more than a year. To date, 47 million individuals have been infected and 1.2 million individuals have died worldwide. Some of the most important coinfections in patients with coronavirus disease 2019 (COVID-19) are opportunistic invasive fungal infections (OIFIs), which are sometimes not rapidly diagnosed and are often diagnosed after death. Aspergillosis and candidiasis are the most prevalent OIFIs in patients with COVID-19. Mycormycosis, cryptococcosis, and other fungal diseases have also been documented more rarely. This review aimed to summarize factors affecting COVID-19 transmission, prevalence, morbidity, and mortality in Iran as well as to review common OIFIs in patients with COVID-19. Immunological factors, underlying diseases, and social, cultural, and environmental factors can affect COVID-19 transmission. There is a need to improve diagnostic and therapeutic criteria for OIFIs a...

Research paper thumbnail of Review of novel human β‐coronavirus ( 2019‐nCoV or SARS‐CoV ‐2) from the food industry perspective—Food plant health principles

Journal of Food Safety, 2020

Coronaviruses, enveloped non-segmented positive-sense RNA viruses, distinguished in the mid-60s c... more Coronaviruses, enveloped non-segmented positive-sense RNA viruses, distinguished in the mid-60s can infect humans and a variety of birds and mammals. The purpose of this study was to review these coronaviruses, especially SARS (because of its very similar gene sequence to the 2019-nCoV or SARS-CoV-2), from the perspective of observing the food plant health principles including observing the personal hygiene principles, that is, identification and prevention of workers suspected of carrying COVID-19 in the food production lines, implementation of the hazard analysis and critical control points (HACCP), good manufacturing practice (GMP), and good hygienic practice (GHP) principles from farm to table; utilizing the appropriate chemical sanitizers, that is, incorporation of copper alloy surfaces in conjunction with effective cleaning regimens; use of food plant surface and cleaning-in-place-program sanitizers; utilizing the different light spectrums, that is, Surface sanitizing with UVC light or surface sanitizing with methylene blue in conjunction with visible light in food production lines; and providing unfavorable environmental conditions for coronavirus survival (minimum heat treatment, for example, low temperature long time and greater for liquid food products, pH ≤3, minimum-storage relative-humidity). Considering these aspects during times and times and places of with the high prevalence of β-coronavirus (2019-nCoV or SARS-CoV-2) will be essential for preventing further outbreaks at the community level.

Research paper thumbnail of Construction of a sensitive and specific lead biosensor using a genetically engineered bacterial system with a luciferase gene reporter

Background A bacterial biosensor refers to genetically engineered bacteria that produces an asses... more Background A bacterial biosensor refers to genetically engineered bacteria that produces an assessable signal in the presence of a physical or chemical agent in the environment. Methods We designed and evaluated a bacterial biosensor expressing a luciferase-reporting gene that is controlled by pbr and cadA promoters in Cupriavidus metallidurans (previously Ralstonia metallidurans ) CH34 and pI258 plasmids of Staphylococcus aureus , respectively, for detection of heavy metals. In the present study, we produced biosensor plasmids designated pGL3-luc/pbr -biosensor and pGL3-luc/cad -biosensor, which were based on the expression of luc+ under the control of the cad promoter and the cadC gene of S. aureus plasmid pI258 and pbr promoter and pbrR gene from plasmid pMOL30 of Cupriavidus metallidurans . Results: We found that the biodegradable pGL3-luc/pbr -biosensor could measure lead concentrations between 1-100 μM in the presence of other metals such as zinc, cadmium, tin and nickel, in t...

Research paper thumbnail of Quinoa as a wheat substitute to improve the textural properties and minimize the carcinogenic acrylamide content of the biscuit

Journal of Food Processing and Preservation, 2020

The substitution of gluten for celiac patients is a great challenge and the majority of gluten-fr... more The substitution of gluten for celiac patients is a great challenge and the majority of gluten-free bakery products available on the market are based on starches. Currently, gluten-free food manufacturers are investing in the use of whole grains including corn, rice, sorghum, buckwheat, amaranth, and quinoa, since the majority of them are rich in fiber, iron, and vitamin B sources. The pseudocereals are considered gluten-free grains with an excellent nutrient profile, capable of diversifying this rising market (Paucean, Man, Muste, & Pop, 2015). Quinoa (Chenopodium quinoa Willd.) is a grain with exceptional nutritional value and high concentrations of protein, all essential amino acids and unsaturated fatty acids. It has a low glycemic index (GI) and contains vitamins, minerals, as well as other beneficial compounds. It is gluten-free by nature (Gordillo-Bastidas,

Research paper thumbnail of Bacterial staphylokinase as a promising third-generation drug in the treatment for vascular occlusion

Molecular Biology Reports, 2019

Vascular occlusion is one of the major causes of mortality and morbidity. Blood vessel blockage c... more Vascular occlusion is one of the major causes of mortality and morbidity. Blood vessel blockage can lead to thrombotic complications such as myocardial infarction, stroke, deep venous thrombosis, peripheral occlusive disease, and pulmonary embolism. Thrombolytic therapy currently aims to rectify this through the administration of recombinant tissue plasminogen activator. Research is underway to design an ideal thrombolytic drug with the lowest risk. Despite the potent clot lysis achievable using approved thrombolytic drugs such as alteplase, reteplase, streptokinase, tenecteplase, and some other fibrinolytic agents, there are some drawbacks, such as high production cost, systemic bleeding, intracranial hemorrhage, vessel re-occlusion by platelet-rich and retracted secondary clots, and non-fibrin specificity. In comparison, bacterial staphylokinase, is a new, small-size plasminogen activator, unlike bacterial streptokinase, it hinders the systemic degradation of fibrinogen and reduces the risk of severe hemorrhage. A fibrin-bound plasmin-staphylokinase complex shows high resistance to a 2-antiplasmin-related inhibition. Staphylokinase has the potential to be considered as a promising thrombolytic agent with properties of cost-effective production and the least side effects.

Research paper thumbnail of Substitution of sesame and peanut defatted-meal milk with egg yolk and evaluation of the rheological and microstructural properties of low-cholesterol mayonnaise

Food Science and Technology International, 2019

Peanut, sesame, and (peanut:sesame (1:1)) meal milk were used as the egg yolk substitute at the l... more Peanut, sesame, and (peanut:sesame (1:1)) meal milk were used as the egg yolk substitute at the levels of 0%, 25%, 50%, 75%, and 100% in mayonnaise. Then, the rheological, textural (hardness, adhesive force, and adhesiveness), and microstructural properties of samples were evaluated on the first day after production. The oscillatory test indicated that all treatments had shear thinning flow behavior and in low-angular frequencies had higher elastic modulus than the viscous modulus (tan δ < 1), but in the P-S50 and P-S100, P75 and S75 in angular frequencies higher than 63 rad.s−1, tan δ was more than one (i.e. G″ > G′) which indicated more viscous modulus (liquid-like flow behavior) than the elastic modulus (gel-like flow behavior). The optical microscopy confirmed that the oil particle size in blank, 25 and 50% of substitution was of smaller size, and the fat droplets had a monotonous and regular form. In 75 and 100% of substitution, the oil particle size was larger and more i...

Research paper thumbnail of Toward a muon-specific electronic structure theory: effective electronic Hartree-Fock equations for muonic molecules

Physical chemistry chemical physics : PCCP, Jan 26, 2018

An effective set of Hartree-Fock (HF) equations are derived for electrons of muonic systems, i.e.... more An effective set of Hartree-Fock (HF) equations are derived for electrons of muonic systems, i.e., molecules containing a positively charged muon, conceiving the muon as a quantum oscillator, which are completely equivalent to the usual two-component HF equations used to derive stationary states of the muonic molecules. In these effective equations, a non-Coulombic potential is added to the orthodox coulomb and exchange potential energy terms, which describes the interaction of the muon and the electrons effectively and is optimized during the self-consistent field cycles. While in the two-component HF equations a muon is treated as a quantum particle, in the effective HF equations it is absorbed into the effective potential and practically transformed into an effective potential field experienced by electrons. The explicit form of the effective potential depends on the nature of muon's vibrations and is derivable from the basis set used to expand the muonic spatial orbital. The...

Research paper thumbnail of The effect of replacing oil with water and NaCl with KCl on soybean oil hydrolysis and oxidation in canned skipjack tuna fish at the end of the 18-month shelf life

Food Science and Biotechnology, 2017

The effects of replacing oil with water (0, 3, 6, and 10% based on total net weight of the produc... more The effects of replacing oil with water (0, 3, 6, and 10% based on total net weight of the product) and replacing NaCl with KCl (0, 50, and 100%) at different replacement levels were surveyed. Hydrolysis (acidity number), peroxide value, and thiobarbituric acid (TBA) index were evaluated at the end of the 18-month shelf life in canned skipjack tuna fish. Results showed that the TBA index was not affected, whereas the peroxide value was affected by replacing oil with water and NaCl with KCl (p>0.05), so that by increasing in replacing oil with water and replacing NaCl with KCl, the peroxide value was significantly decreased (p<0.05). Hydrolysis (acidity number) was affected by replacing oil with water (p<0.05); however, it was not affected by replacing NaCl with KCl (p>0.05). It was found out the best suggestion is 10% replacing oil with water and 50% replacing NaCl with KCl.

Research paper thumbnail of Extending the Domain-Averaged Exchange-Correlation Energies Within the Context of the MC-QTAIM: Tracing Subtle Variations Induced by Isotope Substitution

ChemPhysChem, 2016

Recently, it has been demonstrated that the domain-averaged exchange-correlation energies, V(xc) ... more Recently, it has been demonstrated that the domain-averaged exchange-correlation energies, V(xc) , are capable of tracing the covalent character of atom-atom interactions unequivocally and thus pave the way for detailed bonding analysis within the context of the quantum theory of atoms in molecules (QTAIM) [M. García-Revilla, E. Francisco, P. L. Popelier, A. Martín Pendás, ChemPhysChem 2013, 14, 1211-1218]. Herein, the concept of V(xc) is extended within the context of the newly developed multicomponent QTAIM (MC-QTAIM). The extended version, Veexc , is capable of analyzing nonadiabatic wavefunctions and thus is sensitive to the mass of nuclei and can trace &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;locally&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot; the subtle electronic variations induced by isotope substitution. To demonstrate this capability in practice, ab initio nonadiabatic wavefunctions for three isotopically substituted hydrogen cyanide molecules, in which the hydrogen nucleus was assumed to be a proton, deuterium, or tritium, were derived. The resulting wavefunctions were then used to compute Veexc and it emerged that for the hydrogen-carbon bond, the Veexc was distinct for each isotopic composition and varied in line with chemical expectations. Indeed, the introduction of Veexc paves the way for the investigation of vast numbers of structural and kinetic isotope effects within the context of the MC-QTAIM.

Research paper thumbnail of Study on the Effect of Replacing Cinnamon with Cardamom and Animal Butter with Plant Butter on Physicochemical Properties of Sohan-Polki

Food Science and Technology, 2020

Research paper thumbnail of Survey on the Effect of Sucrose Replacement with Stevia (Stevia rebaudiana) Powder and Tragacanth Gum on Physico-chemical, Rheological and Sensorial Properties of Apricot Nectar

Pizhūhish va Nuāvarī dar ̒Ulūm va Sanāyi̒-i Ghaz̠āyī, 2018

Awareness of people about the suitable nutrition, can influence human nutrition and lead manufact... more Awareness of people about the suitable nutrition, can influence human nutrition and lead manufacturers to produce food products with low fat, sugar and salt, but with high fiber. One of the special diets is production of low-calorie foods with less sugar. In this study the effect of replacing sucrose with stevioside (0, 50 and 100%) and tragacanth gum (0.5%) in low-calorie apricot nectar was investigated. In the present study the tests included acidity, pH, total solids, total sugar, density, antioxidant activity (DPPH), total phenol, viscosity, lightness and sensory evaluation. The results showed that the Stevia addition had no significant effect on acidity and pH; however, it caused significant changes in the total solids and density of treatments. Total sugar and viscosity reduced with increasing Stevia addition. Antioxidant activity of samples increased with Stevia addition and, in all samples these factors improved through the addition of tragacanth gum. Additionally, rheologic...

Research paper thumbnail of Optimization of dietary Sohan formulation for celiac and diabetic patients by replacing sucrose with isomalt and complete replacing of wheat flour with soybean meal and corn flour by response surface methodology

Food Science and Technology, 2021

Research paper thumbnail of Evaluation of antioxidant properties of sodium-selenite microencapsulated in antioxidant-free soybean oil refined

Food Science and Technology, 2021

Research paper thumbnail of The Effect of Spray Dryer Atomizer Speed on Casein Micelle Size and Physicochemical Properties of White Cheese

In this research, an industrial spray dryer was used and the effects of atomizer speed on the phy... more In this research, an industrial spray dryer was used and the effects of atomizer speed on the physicochemical properties of milk powder, the textural and sensory characteristics of white cheese made from this milk powder were evaluated. For this purpose, whole milk was converted into powder by using three different speeds (10,000, 11,000, and 12,000 rpm). The results showed that by increasing atomizer speed in the spray dryer, the average size of casein micelle is significantly decreased (P < 0.05), whereas no significant effect is observed on the chemical properties of milk powder. White cheese characteristics indicated that by increasing atomizer speed, texture parameters, such as hardness, mastication, and gumminess were significantly reduced (P < 0.05). Sensory evaluation also revealed that the cheese samples prepared with dried milk produced at 12,000 rpm were highly accepted by the panelists. Overall, the findings suggested that 12,000 rpm is the optimal atomizer speed f...

Research paper thumbnail of Investigation of sugar and fat substitution with malt extract and inulin in order to prepare dietary syrup used for probiotic ice cream

Food Science and Technology, 2021

Research paper thumbnail of Physico-chemical characteristics and antioxidant activity of honey containing added Dill extract in the process and biological methods

Food Science and Technology International, 2019

Research paper thumbnail of MPC-based Lateral Controller with Look-Ahead Design for Autonomous Multi-vehicle Merging into Platoon

2019 American Control Conference (ACC), 2019

In this paper a Model Predictive Control (MPC)-based approach is implemented to control the later... more In this paper a Model Predictive Control (MPC)-based approach is implemented to control the lateral maneuver of nonlinear vehicle dynamics. The controller is then applied to a multi-vehicle merging strategy for several vehicles to autonomously merge into a platoon using a variable-gap lateral reference trajectory. The MPC controller features a look-ahead design so that the controller could take actions in advance and thus improve the tracking objective. A combination of constraints, and slack variables-which quantify constraints violation-are chosen to guarantee a safe, efficient, and comfortable ride. The performance of the linear MPC controller is evaluated against a nonlinear plant to demonstrate a more realistic scenario.

Research paper thumbnail of Optimization of cupcake formulation by replacement of wheat flour with different levels of eggplant fiber using response surface methodology

Food Science and Technology, 2021

This study aimed to design and produce optimal formula of cupcakes containing eggplant fiber by s... more This study aimed to design and produce optimal formula of cupcakes containing eggplant fiber by surface response methodology (RSM). The wheat flour replaced with eggplant fiber in five levels, 0-40%, whole-egg and sugar were set at the same time, 55-75% and 70-90% based on (wheat-flour + eggplant-fiber) weight, respectively. Considering the most important textural properties (hardness, cohesiveness, springiness, gumminess and chewiness), density, weight, and also by mean comparisons with Duncan's test at the level of 5% significance, optimal formulas include: formula (a) (12% eggplant-fiber, 71% whole-egg, 70% sugar) and formula (b): (8% eggplant-fiber, 57% whole-egg, 70% sugar) were appropriately suggested. Chemical properties of the optimal formulas including, protein, fat, carbohydrate, moisture, insoluble ash in acid and calorie were calculated and compared with the blank. Using of the eggplant-fiber in cupcake formulation caused calorie reduction and increased its nutritional value. Formula (b), in terms of many factors, demonstrated similarity to the blank. The eggplant-fiber had an impact on all of the textural properties except springiness. The impacts of whole-egg content on springiness, chewiness and density are also remarkable. Sugar content will be shown in weight differences and is expressed as one of the most effective variables on sample weight.

Research paper thumbnail of Optimization of hydrolysis conditions (temperature, time, and concentration of alkalase) of rainbow trout viscera using the response surface methodology

Journal of Food Processing and Preservation, 2021

Research paper thumbnail of Migration of Various Nanoparticles into Food Samples: A Review

Foods, 2021

Nanotechnology has provided new opportunities for the food industry with its applications in food... more Nanotechnology has provided new opportunities for the food industry with its applications in food packaging. The addition of nanoparticles, such as clay, silver and copper, can improve the mechanical and antimicrobial properties of food packaging. However, nanoparticles may have an adverse impact on human health. This has led to legislative and regulatory concerns. The inhibitory effects of nano packaging on different microorganisms, such as Salmonella, E. coli, and molds, have been studied. Nanoparticles, like other materials, may have a diverse set of properties that need to be determined. In this review, different features of silver, clay and copper nanoparticles, such as their anti-microbial, cell toxicity, genetic toxicity, mechanical properties, and migration, are critically evaluated in the case of food packaging. Specifically, the viewpoints of WHO, FDA, and ESFA, concerning the nano-silver application in food packaging, are discussed as well.

Research paper thumbnail of Predisposing factors of important invasive fungal coinfections in COVID-19 patients: a review article

Journal of International Medical Research, 2021

Severe acute respiratory syndrome coronavirus-2 has caused a devastating pandemic lasting for mor... more Severe acute respiratory syndrome coronavirus-2 has caused a devastating pandemic lasting for more than a year. To date, 47 million individuals have been infected and 1.2 million individuals have died worldwide. Some of the most important coinfections in patients with coronavirus disease 2019 (COVID-19) are opportunistic invasive fungal infections (OIFIs), which are sometimes not rapidly diagnosed and are often diagnosed after death. Aspergillosis and candidiasis are the most prevalent OIFIs in patients with COVID-19. Mycormycosis, cryptococcosis, and other fungal diseases have also been documented more rarely. This review aimed to summarize factors affecting COVID-19 transmission, prevalence, morbidity, and mortality in Iran as well as to review common OIFIs in patients with COVID-19. Immunological factors, underlying diseases, and social, cultural, and environmental factors can affect COVID-19 transmission. There is a need to improve diagnostic and therapeutic criteria for OIFIs a...

Research paper thumbnail of Review of novel human β‐coronavirus ( 2019‐nCoV or SARS‐CoV ‐2) from the food industry perspective—Food plant health principles

Journal of Food Safety, 2020

Coronaviruses, enveloped non-segmented positive-sense RNA viruses, distinguished in the mid-60s c... more Coronaviruses, enveloped non-segmented positive-sense RNA viruses, distinguished in the mid-60s can infect humans and a variety of birds and mammals. The purpose of this study was to review these coronaviruses, especially SARS (because of its very similar gene sequence to the 2019-nCoV or SARS-CoV-2), from the perspective of observing the food plant health principles including observing the personal hygiene principles, that is, identification and prevention of workers suspected of carrying COVID-19 in the food production lines, implementation of the hazard analysis and critical control points (HACCP), good manufacturing practice (GMP), and good hygienic practice (GHP) principles from farm to table; utilizing the appropriate chemical sanitizers, that is, incorporation of copper alloy surfaces in conjunction with effective cleaning regimens; use of food plant surface and cleaning-in-place-program sanitizers; utilizing the different light spectrums, that is, Surface sanitizing with UVC light or surface sanitizing with methylene blue in conjunction with visible light in food production lines; and providing unfavorable environmental conditions for coronavirus survival (minimum heat treatment, for example, low temperature long time and greater for liquid food products, pH ≤3, minimum-storage relative-humidity). Considering these aspects during times and times and places of with the high prevalence of β-coronavirus (2019-nCoV or SARS-CoV-2) will be essential for preventing further outbreaks at the community level.

Research paper thumbnail of Construction of a sensitive and specific lead biosensor using a genetically engineered bacterial system with a luciferase gene reporter

Background A bacterial biosensor refers to genetically engineered bacteria that produces an asses... more Background A bacterial biosensor refers to genetically engineered bacteria that produces an assessable signal in the presence of a physical or chemical agent in the environment. Methods We designed and evaluated a bacterial biosensor expressing a luciferase-reporting gene that is controlled by pbr and cadA promoters in Cupriavidus metallidurans (previously Ralstonia metallidurans ) CH34 and pI258 plasmids of Staphylococcus aureus , respectively, for detection of heavy metals. In the present study, we produced biosensor plasmids designated pGL3-luc/pbr -biosensor and pGL3-luc/cad -biosensor, which were based on the expression of luc+ under the control of the cad promoter and the cadC gene of S. aureus plasmid pI258 and pbr promoter and pbrR gene from plasmid pMOL30 of Cupriavidus metallidurans . Results: We found that the biodegradable pGL3-luc/pbr -biosensor could measure lead concentrations between 1-100 μM in the presence of other metals such as zinc, cadmium, tin and nickel, in t...

Research paper thumbnail of Quinoa as a wheat substitute to improve the textural properties and minimize the carcinogenic acrylamide content of the biscuit

Journal of Food Processing and Preservation, 2020

The substitution of gluten for celiac patients is a great challenge and the majority of gluten-fr... more The substitution of gluten for celiac patients is a great challenge and the majority of gluten-free bakery products available on the market are based on starches. Currently, gluten-free food manufacturers are investing in the use of whole grains including corn, rice, sorghum, buckwheat, amaranth, and quinoa, since the majority of them are rich in fiber, iron, and vitamin B sources. The pseudocereals are considered gluten-free grains with an excellent nutrient profile, capable of diversifying this rising market (Paucean, Man, Muste, & Pop, 2015). Quinoa (Chenopodium quinoa Willd.) is a grain with exceptional nutritional value and high concentrations of protein, all essential amino acids and unsaturated fatty acids. It has a low glycemic index (GI) and contains vitamins, minerals, as well as other beneficial compounds. It is gluten-free by nature (Gordillo-Bastidas,

Research paper thumbnail of Bacterial staphylokinase as a promising third-generation drug in the treatment for vascular occlusion

Molecular Biology Reports, 2019

Vascular occlusion is one of the major causes of mortality and morbidity. Blood vessel blockage c... more Vascular occlusion is one of the major causes of mortality and morbidity. Blood vessel blockage can lead to thrombotic complications such as myocardial infarction, stroke, deep venous thrombosis, peripheral occlusive disease, and pulmonary embolism. Thrombolytic therapy currently aims to rectify this through the administration of recombinant tissue plasminogen activator. Research is underway to design an ideal thrombolytic drug with the lowest risk. Despite the potent clot lysis achievable using approved thrombolytic drugs such as alteplase, reteplase, streptokinase, tenecteplase, and some other fibrinolytic agents, there are some drawbacks, such as high production cost, systemic bleeding, intracranial hemorrhage, vessel re-occlusion by platelet-rich and retracted secondary clots, and non-fibrin specificity. In comparison, bacterial staphylokinase, is a new, small-size plasminogen activator, unlike bacterial streptokinase, it hinders the systemic degradation of fibrinogen and reduces the risk of severe hemorrhage. A fibrin-bound plasmin-staphylokinase complex shows high resistance to a 2-antiplasmin-related inhibition. Staphylokinase has the potential to be considered as a promising thrombolytic agent with properties of cost-effective production and the least side effects.

Research paper thumbnail of Substitution of sesame and peanut defatted-meal milk with egg yolk and evaluation of the rheological and microstructural properties of low-cholesterol mayonnaise

Food Science and Technology International, 2019

Peanut, sesame, and (peanut:sesame (1:1)) meal milk were used as the egg yolk substitute at the l... more Peanut, sesame, and (peanut:sesame (1:1)) meal milk were used as the egg yolk substitute at the levels of 0%, 25%, 50%, 75%, and 100% in mayonnaise. Then, the rheological, textural (hardness, adhesive force, and adhesiveness), and microstructural properties of samples were evaluated on the first day after production. The oscillatory test indicated that all treatments had shear thinning flow behavior and in low-angular frequencies had higher elastic modulus than the viscous modulus (tan δ < 1), but in the P-S50 and P-S100, P75 and S75 in angular frequencies higher than 63 rad.s−1, tan δ was more than one (i.e. G″ > G′) which indicated more viscous modulus (liquid-like flow behavior) than the elastic modulus (gel-like flow behavior). The optical microscopy confirmed that the oil particle size in blank, 25 and 50% of substitution was of smaller size, and the fat droplets had a monotonous and regular form. In 75 and 100% of substitution, the oil particle size was larger and more i...

Research paper thumbnail of Toward a muon-specific electronic structure theory: effective electronic Hartree-Fock equations for muonic molecules

Physical chemistry chemical physics : PCCP, Jan 26, 2018

An effective set of Hartree-Fock (HF) equations are derived for electrons of muonic systems, i.e.... more An effective set of Hartree-Fock (HF) equations are derived for electrons of muonic systems, i.e., molecules containing a positively charged muon, conceiving the muon as a quantum oscillator, which are completely equivalent to the usual two-component HF equations used to derive stationary states of the muonic molecules. In these effective equations, a non-Coulombic potential is added to the orthodox coulomb and exchange potential energy terms, which describes the interaction of the muon and the electrons effectively and is optimized during the self-consistent field cycles. While in the two-component HF equations a muon is treated as a quantum particle, in the effective HF equations it is absorbed into the effective potential and practically transformed into an effective potential field experienced by electrons. The explicit form of the effective potential depends on the nature of muon's vibrations and is derivable from the basis set used to expand the muonic spatial orbital. The...

Research paper thumbnail of The effect of replacing oil with water and NaCl with KCl on soybean oil hydrolysis and oxidation in canned skipjack tuna fish at the end of the 18-month shelf life

Food Science and Biotechnology, 2017

The effects of replacing oil with water (0, 3, 6, and 10% based on total net weight of the produc... more The effects of replacing oil with water (0, 3, 6, and 10% based on total net weight of the product) and replacing NaCl with KCl (0, 50, and 100%) at different replacement levels were surveyed. Hydrolysis (acidity number), peroxide value, and thiobarbituric acid (TBA) index were evaluated at the end of the 18-month shelf life in canned skipjack tuna fish. Results showed that the TBA index was not affected, whereas the peroxide value was affected by replacing oil with water and NaCl with KCl (p>0.05), so that by increasing in replacing oil with water and replacing NaCl with KCl, the peroxide value was significantly decreased (p<0.05). Hydrolysis (acidity number) was affected by replacing oil with water (p<0.05); however, it was not affected by replacing NaCl with KCl (p>0.05). It was found out the best suggestion is 10% replacing oil with water and 50% replacing NaCl with KCl.

Research paper thumbnail of Extending the Domain-Averaged Exchange-Correlation Energies Within the Context of the MC-QTAIM: Tracing Subtle Variations Induced by Isotope Substitution

ChemPhysChem, 2016

Recently, it has been demonstrated that the domain-averaged exchange-correlation energies, V(xc) ... more Recently, it has been demonstrated that the domain-averaged exchange-correlation energies, V(xc) , are capable of tracing the covalent character of atom-atom interactions unequivocally and thus pave the way for detailed bonding analysis within the context of the quantum theory of atoms in molecules (QTAIM) [M. García-Revilla, E. Francisco, P. L. Popelier, A. Martín Pendás, ChemPhysChem 2013, 14, 1211-1218]. Herein, the concept of V(xc) is extended within the context of the newly developed multicomponent QTAIM (MC-QTAIM). The extended version, Veexc , is capable of analyzing nonadiabatic wavefunctions and thus is sensitive to the mass of nuclei and can trace &amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot;locally&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;quot; the subtle electronic variations induced by isotope substitution. To demonstrate this capability in practice, ab initio nonadiabatic wavefunctions for three isotopically substituted hydrogen cyanide molecules, in which the hydrogen nucleus was assumed to be a proton, deuterium, or tritium, were derived. The resulting wavefunctions were then used to compute Veexc and it emerged that for the hydrogen-carbon bond, the Veexc was distinct for each isotopic composition and varied in line with chemical expectations. Indeed, the introduction of Veexc paves the way for the investigation of vast numbers of structural and kinetic isotope effects within the context of the MC-QTAIM.