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Papers by pavel turčáni
Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic, Sep 30, 2015
Česká stomatologie/Praktické zubní lékařství, 2020
Asian Pacific Journal of Allergy and Immunology, 2013
Objectives: Obstructive sleep apnea (OSA) occurs more commonly in asthma patients than in the gen... more Objectives: Obstructive sleep apnea (OSA) occurs more commonly in asthma patients than in the general population and can complicate asthma management. The aim of this study was to evaluate the presence of OSA in patients with difficult-to-treat asthma (DTA) and to investigate the sleep quality in these patients. Methods: Patients with DTA were recruited from the adult allergy clinic of a tertiary care hospital. After completing the Sleep Questionnaire and Epworth Sleepiness Scale, all participants underwent overnight polysomnography. The demographic and asthma severity assessments included the following measures: the age at diagnosis, duration of illness, smoking and atopy status, results of pulmonary function tests, number of asthma control medications used, and number of hospitalizations and emergency room visits because of asthma and analgesic hypersensitivity according to apnea-hypopnea index (AHI) scores. Results: We analyzed 47 (M:9/F:38) DTA patients with a mean age of 48.74±9.45 years. The mean duration of asthma was 9.17±6.5 years. Twenty-four (51.1%) patients were atopic. The analgesic hypersensitivity rate was 27.7%. Fourteen patients (29.8%) were former smokers and 2 patients were current smokers. Sleep quality was impaired in all patients. Thirty-five patients (74.5%) had OSA, 11 of whom had mild OSA, and 24 patients had moderate-severe OSA. The presence of OSA was not statistically correlated with asthma characteristics. Conclusion: The study showed that there is a remarkably high prevalence of OSA in DTA. Although no statistically significant relationship between the presence of OSA and clinical asthma characteristics was identified, all DTA patients should be assessed for OSA.
Pokud se u jednoho pacienta vyskytuje soucasně syndrom obstrukcni spankove apnoe (OSA) a chronick... more Pokud se u jednoho pacienta vyskytuje soucasně syndrom obstrukcni spankove apnoe (OSA) a chronicka obstrukcni plicni nemoc (CHOPN), jedna se o overlap syndrom CHOPN - OSA. O prevalenci OSA u pacientů s CHOPN neexistuji přesna data. Cilem prace bylo zjistit, jak casto se mezi pacienty, kteři jsou hospitalizovani pro exacerbaci CHOPN vyskytuje OSA. Popsat charakteristiky těchto pacientů a zjistit, ktere z nich koreluji s výskytem OSA. Metody: V průběhu 4 měsiců bylo na Klinice nemoci plicnich hospitalizovano pro exacerbaci CHOPN 101 pacientů. Konsekutivně jdouci pacienty (n=79) jsme zhodnotili s ohledem na vstupni kriteria a 35 z nich vysetřili polygrafii. Pro zhodnoceni výsledků byla použita popisna statistika, Mann-Whitney test, Kruskal-Wallis test, Spearmanova korelacniho koeficientu, a Fisherova exaktniho testu. Výsledky: U 18 z 35 (51.4 %) vysetřených byla hodnota AHI ≥ 5 (kriterium přitomnosti OSA). U 9 z 35 (25.7 %) byla hodnota AHI ≥ 15 (kriterium přiděleni NIV, ktere je platn...
Summing up their own experience with endobronchial treatment in general anesthesia using jet vent... more Summing up their own experience with endobronchial treatment in general anesthesia using jet ventilation, the authors answer the title question with guarded optimism.
Conclusions: Endobronchial treatment (electrosurgary and laser brochoscopy) is palliative therape... more Conclusions: Endobronchial treatment (electrosurgary and laser brochoscopy) is palliative therapeutic procedure with acceptable rate of complications in patients with endobronchial growth of malignancies and in patients with ASA classification III and IV.
Ethic and Economics, 2017
Introduction: Adherence to medical advice reflects an active patient role in treatment. Non fulfi... more Introduction: Adherence to medical advice reflects an active patient role in treatment. Non fulfillment adherence means the prescribed medication is never filled or initiated. Aim: To find out how much mediacation is prescribed to COPD and astma patiens by pneumologists in the outpatient department which was not filled during one year. Methods: From one particular insurance company, we collected data about which medications were filled in the pharmacy, and compared this to data about which medication was prescribed for patients with COPD and astma in our outpatient department. Results: The diference between the amout of medication which was prescribed and mediation which was not filled in a pharmacy was (%;packages): ipratropium bromide (34;436), ipratropium bromide/formoterol (30;359), roflumilast (38;300), theophylline (24;598), formoterol (32;171), indacaterol (34;53), salmeterol/fluticason (26;508), tiotropium bromide (23;617), budesonide/formoterol (22;385). The total price of the prescribed-but-not-filled medication was € 30493 in one year. Conclusion: In one year, the difference between the amount of prescribed and filled medication ranged between 22-38 % (53-617 packages) according to prescribed medication. This result can be used for making better systemic strategies to enhance adherence.
Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic, Sep 30, 2015
Česká stomatologie/Praktické zubní lékařství, 2020
Asian Pacific Journal of Allergy and Immunology, 2013
Objectives: Obstructive sleep apnea (OSA) occurs more commonly in asthma patients than in the gen... more Objectives: Obstructive sleep apnea (OSA) occurs more commonly in asthma patients than in the general population and can complicate asthma management. The aim of this study was to evaluate the presence of OSA in patients with difficult-to-treat asthma (DTA) and to investigate the sleep quality in these patients. Methods: Patients with DTA were recruited from the adult allergy clinic of a tertiary care hospital. After completing the Sleep Questionnaire and Epworth Sleepiness Scale, all participants underwent overnight polysomnography. The demographic and asthma severity assessments included the following measures: the age at diagnosis, duration of illness, smoking and atopy status, results of pulmonary function tests, number of asthma control medications used, and number of hospitalizations and emergency room visits because of asthma and analgesic hypersensitivity according to apnea-hypopnea index (AHI) scores. Results: We analyzed 47 (M:9/F:38) DTA patients with a mean age of 48.74±9.45 years. The mean duration of asthma was 9.17±6.5 years. Twenty-four (51.1%) patients were atopic. The analgesic hypersensitivity rate was 27.7%. Fourteen patients (29.8%) were former smokers and 2 patients were current smokers. Sleep quality was impaired in all patients. Thirty-five patients (74.5%) had OSA, 11 of whom had mild OSA, and 24 patients had moderate-severe OSA. The presence of OSA was not statistically correlated with asthma characteristics. Conclusion: The study showed that there is a remarkably high prevalence of OSA in DTA. Although no statistically significant relationship between the presence of OSA and clinical asthma characteristics was identified, all DTA patients should be assessed for OSA.
Pokud se u jednoho pacienta vyskytuje soucasně syndrom obstrukcni spankove apnoe (OSA) a chronick... more Pokud se u jednoho pacienta vyskytuje soucasně syndrom obstrukcni spankove apnoe (OSA) a chronicka obstrukcni plicni nemoc (CHOPN), jedna se o overlap syndrom CHOPN - OSA. O prevalenci OSA u pacientů s CHOPN neexistuji přesna data. Cilem prace bylo zjistit, jak casto se mezi pacienty, kteři jsou hospitalizovani pro exacerbaci CHOPN vyskytuje OSA. Popsat charakteristiky těchto pacientů a zjistit, ktere z nich koreluji s výskytem OSA. Metody: V průběhu 4 měsiců bylo na Klinice nemoci plicnich hospitalizovano pro exacerbaci CHOPN 101 pacientů. Konsekutivně jdouci pacienty (n=79) jsme zhodnotili s ohledem na vstupni kriteria a 35 z nich vysetřili polygrafii. Pro zhodnoceni výsledků byla použita popisna statistika, Mann-Whitney test, Kruskal-Wallis test, Spearmanova korelacniho koeficientu, a Fisherova exaktniho testu. Výsledky: U 18 z 35 (51.4 %) vysetřených byla hodnota AHI ≥ 5 (kriterium přitomnosti OSA). U 9 z 35 (25.7 %) byla hodnota AHI ≥ 15 (kriterium přiděleni NIV, ktere je platn...
Summing up their own experience with endobronchial treatment in general anesthesia using jet vent... more Summing up their own experience with endobronchial treatment in general anesthesia using jet ventilation, the authors answer the title question with guarded optimism.
Conclusions: Endobronchial treatment (electrosurgary and laser brochoscopy) is palliative therape... more Conclusions: Endobronchial treatment (electrosurgary and laser brochoscopy) is palliative therapeutic procedure with acceptable rate of complications in patients with endobronchial growth of malignancies and in patients with ASA classification III and IV.
Ethic and Economics, 2017
Introduction: Adherence to medical advice reflects an active patient role in treatment. Non fulfi... more Introduction: Adherence to medical advice reflects an active patient role in treatment. Non fulfillment adherence means the prescribed medication is never filled or initiated. Aim: To find out how much mediacation is prescribed to COPD and astma patiens by pneumologists in the outpatient department which was not filled during one year. Methods: From one particular insurance company, we collected data about which medications were filled in the pharmacy, and compared this to data about which medication was prescribed for patients with COPD and astma in our outpatient department. Results: The diference between the amout of medication which was prescribed and mediation which was not filled in a pharmacy was (%;packages): ipratropium bromide (34;436), ipratropium bromide/formoterol (30;359), roflumilast (38;300), theophylline (24;598), formoterol (32;171), indacaterol (34;53), salmeterol/fluticason (26;508), tiotropium bromide (23;617), budesonide/formoterol (22;385). The total price of the prescribed-but-not-filled medication was € 30493 in one year. Conclusion: In one year, the difference between the amount of prescribed and filled medication ranged between 22-38 % (53-617 packages) according to prescribed medication. This result can be used for making better systemic strategies to enhance adherence.