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Papers by sadia parween

Research paper thumbnail of Knowledge, Attitude and Practices Regarding Human Papillomavirus (HPV) Vaccination Among Adolescent Girls in Bihar and Evaluate the Factors Influencing It- a Cross Sectional Study at a Tertiary Care Hospital

Research paper thumbnail of Pregnancy Related Acute Kidney Injury; Our Experience at Tertiary Level Hospital

International Journal of Contemporary Medical Research [IJCMR]

Introduction: Pregnancy-related acute kidney injury (AKI) is a common occurrence and is associate... more Introduction: Pregnancy-related acute kidney injury (AKI) is a common occurrence and is associated with substantial maternal morbidity and mortality in developing countries. It may comprise up to 25% of the referrals to dialysis centers in developing countries. Acute kidney injury in pregnancy bears a high risk of bilateral renal cortical necrosis and consequently chronic renal failure. Study aimed to evaluate the contributing factors responsible for pregnancy-related Acute kidney injury and to assess the outcome of patients with pregnancy-related Acute kidney injury. Material and methods: The present study is a prospective study of patients with obstetric complications leading to Acute kidney injury admitted in Obs and Gynae Deptt and nephrology deptt of IGIMS for a period of one year. Pregnant women who are included in the study are those who were healthy previously and had developed Acute kidney injury-oliguria (Urine output <400 ml/d) and azotemia (Serum creatinine >2 mg%) due to pregnancy related complications. Results: Pregnancy related complications was present in 38 patients admitted in our hospital with acute kidney injury in one year period. Out of these 37% (14) of patients were in early stage of pregnancy while 63% (24) were in later stage of pregnancy and puerperium. Causes of AKI was post abortal sepsis in 23.6%, puerperal sepsis in 26.3%, haemorrhagic shock in 23.6%, eclampsia/pre-eclampsia/HELLP syndrome in 21%, IUD in 2 nd trimester with sepsis in 2.6% and acute fatty liver of pregnancy in 2.6% of cases. Sepsis was the major cause accounting upto 52.6% of cases. Approximately 52.6% (20) of patients improved on treatment and dialysis, 21% did not improve (8), 13.15% (5) died and 13.15% (5) left against medical advice. Cause of death in 80% (4 out of 5) of patients was sepsis. Renal biopsy was performed on 62.5% of patients who did not improve (5 out of 8 patients). Renal transplant was done in 1 patients. Conclusion: Obstetric AKI is still a critical situation in developing countries and rare entity in developed countries. Maternal mortality has decreased but sepsis still accounts for majority of cases. Therefore early diagnosis and treatment is the need of the hour.

Research paper thumbnail of Impact of Meconium-Stained Amniotic Fluid on Neonatal Outcome in a Tertiary Hospital

Cureus, Apr 25, 2022

The aim of this study was to determine the perinatal outcome of pregnant patients complicated wit... more The aim of this study was to determine the perinatal outcome of pregnant patients complicated with meconium-stained amniotic fluid (MSAF) compared with clear amniotic fluid.

Research paper thumbnail of Retrospective study of ectopic pregnancy in tertiary care centre

Background: Ectopic pregnancy is one in which fertilized ovum become implanted in site other than... more Background: Ectopic pregnancy is one in which fertilized ovum become implanted in site other than normal uterine cavity. Ectopic pregnancy commonly occurs in the fallopian tube. Ectopic pregnancy is the leading cause of maternal death in early pregnancy. The diagnosis of ectopic pregnancy is complicated by wide spectrum of clinical presentations, from asymptomatic cases to acute abdomen, and hemodynamic shock. There is considerable regional variation in its incidence. Materials and methods: Retrospective analysis of all cases of ectopic pregnancy admitted in IGIMS, Patna was done from January 2014 to December 2016. Results: The incidence of ectopic pregnancy in present study was 2.1%. Majority of patients were multigravida (94.1%) and in the age group of 25-35 years (70.4%). PID was the strongest risk factor found in 35.29%. Other risk factors were tube ligation (23%), LSCS (11.76%), history of abortion/MTP (17.64%). Commonest clinical presentation was pain abdomen (88.23%) followed...

Research paper thumbnail of Colposcopic evaluation of cervix in symptomatic women and its correlation with Pap smear. A prospective study at a tertiary care centre

Journal of Family Medicine and Primary Care, 2021

Introduction: Back in India, cervical cancer is the second most frequent cancer in women (aged 15... more Introduction: Back in India, cervical cancer is the second most frequent cancer in women (aged 15-45 years) following breast cancer, accounting for nearly 14% of all female cancer cases. The aim of this study is to yell the findings of pap smear with colposcopy and directed biopsy (if needed) and to evaluate the usefulness of colposcopy in discovering the premalignant and malignant lesions of the cervix. Methods: This is a prospective observational analysis of 150 symptomatic women attending the gynecology OPD of Indira Gandhi Institute of Medical Sciences, Patna, for a period of one year from 2019 to 2020. Assessment of symptomatic women was completed with a pap smear, colposcopy, and biopsy in selected instances. Statistical Analysis Used: MS Excel spreadsheet application, SPSS v23 (IBM Corp.), was used for data analysis. Results: The expression age (years) has been 34.68 ± 8.05. The sensitivity and specificity of pap smear were 91.7% and 45.45%, respectively, whereas the sensitivity and specificity of colposcopy were 83.3% and 72.72%, respectively, in the present study. Conclusions: Pap smear had low specificity as compared to colposcopy. Hence simultaneous use of colposcopy has shown to rise in the rate of carcinoma cervix discovery in symptomatic women.

Research paper thumbnail of Prevalence, Etiology, and Associated Symptoms of Vaginal Discharge During Pregnancy in Women Seen in a Tertiary Care Hospital in Bihar

Cureus, 2021

Introduction Vaginal discharge is the most frequent complaint during pregnancy, leading to numero... more Introduction Vaginal discharge is the most frequent complaint during pregnancy, leading to numerous complications in both the mother and fetus. Aim The goal of this study was to determine the prevalence of vaginal discharge, investigate its common infectious causes and associated symptoms during pregnancy. Methods This hospital-based cross-sectional study performed over one year evaluated 200 expectant mothers with vaginal discharge at any trimester in the Department of Obstetrics and Gynecology, in cooperation with the Microbiology section, of Indira Gandhi Institute of Medical Science, Patna. Results The mean age of the mothers was 26.84±5.51 years (range 19-42 years). Most of the patients (47.5%) were in the age group of 26-35 years, belonged to the lower socioeconomic class (67.5%), gravida 3 or more (43.5%), and presented in the third trimester. The prevalence of pathological discharge in pregnancy was 148/308 (48.05%). A positive culture was obtained in 105 (52.5%), and negati...

Research paper thumbnail of Neonatal and maternal outcome in oligohydramnios: a prospective study

International Journal of Contemporary Pediatrics, 2018

Background: Oligohydramnios presents a threat to the fetus and has been correlated with increased... more Background: Oligohydramnios presents a threat to the fetus and has been correlated with increased risk of intrauterine growth retardation, meconium aspiration syndrome, severe birth asphyxia, low APGAR scores and congenital abnormities. It is associated with perinatal morbidity and mortality and maternal morbidity in a significant number of cases. Therefore, early detection of oligohydramnios and its management is important. Aim of this study was to know the fetal and maternal outcome in oligohydramnios.Methods: 90 patients in third trimester of pregnancy with Oligohydramnios were selected after satisfying inclusion and exclusion criteria. A detailed history and examination were done. All required investigation done. Oligohydramnios confirmed by measuring Amniotic fluid index (AFI).Results: Mean maternal age-26.1 years. Incidence of oligohydramnios was more in primipara (64.4%) in our study. And operative morbidity was also more in primipara (51.7%). Most common cause of Oligohydram...

Research paper thumbnail of Knowledge, Attitude and Practices Regarding Human Papillomavirus (HPV) Vaccination Among Adolescent Girls in Bihar and Evaluate the Factors Influencing It- a Cross Sectional Study at a Tertiary Care Hospital

Research paper thumbnail of Pregnancy Related Acute Kidney Injury; Our Experience at Tertiary Level Hospital

International Journal of Contemporary Medical Research [IJCMR]

Introduction: Pregnancy-related acute kidney injury (AKI) is a common occurrence and is associate... more Introduction: Pregnancy-related acute kidney injury (AKI) is a common occurrence and is associated with substantial maternal morbidity and mortality in developing countries. It may comprise up to 25% of the referrals to dialysis centers in developing countries. Acute kidney injury in pregnancy bears a high risk of bilateral renal cortical necrosis and consequently chronic renal failure. Study aimed to evaluate the contributing factors responsible for pregnancy-related Acute kidney injury and to assess the outcome of patients with pregnancy-related Acute kidney injury. Material and methods: The present study is a prospective study of patients with obstetric complications leading to Acute kidney injury admitted in Obs and Gynae Deptt and nephrology deptt of IGIMS for a period of one year. Pregnant women who are included in the study are those who were healthy previously and had developed Acute kidney injury-oliguria (Urine output <400 ml/d) and azotemia (Serum creatinine >2 mg%) due to pregnancy related complications. Results: Pregnancy related complications was present in 38 patients admitted in our hospital with acute kidney injury in one year period. Out of these 37% (14) of patients were in early stage of pregnancy while 63% (24) were in later stage of pregnancy and puerperium. Causes of AKI was post abortal sepsis in 23.6%, puerperal sepsis in 26.3%, haemorrhagic shock in 23.6%, eclampsia/pre-eclampsia/HELLP syndrome in 21%, IUD in 2 nd trimester with sepsis in 2.6% and acute fatty liver of pregnancy in 2.6% of cases. Sepsis was the major cause accounting upto 52.6% of cases. Approximately 52.6% (20) of patients improved on treatment and dialysis, 21% did not improve (8), 13.15% (5) died and 13.15% (5) left against medical advice. Cause of death in 80% (4 out of 5) of patients was sepsis. Renal biopsy was performed on 62.5% of patients who did not improve (5 out of 8 patients). Renal transplant was done in 1 patients. Conclusion: Obstetric AKI is still a critical situation in developing countries and rare entity in developed countries. Maternal mortality has decreased but sepsis still accounts for majority of cases. Therefore early diagnosis and treatment is the need of the hour.

Research paper thumbnail of Impact of Meconium-Stained Amniotic Fluid on Neonatal Outcome in a Tertiary Hospital

Cureus, Apr 25, 2022

The aim of this study was to determine the perinatal outcome of pregnant patients complicated wit... more The aim of this study was to determine the perinatal outcome of pregnant patients complicated with meconium-stained amniotic fluid (MSAF) compared with clear amniotic fluid.

Research paper thumbnail of Retrospective study of ectopic pregnancy in tertiary care centre

Background: Ectopic pregnancy is one in which fertilized ovum become implanted in site other than... more Background: Ectopic pregnancy is one in which fertilized ovum become implanted in site other than normal uterine cavity. Ectopic pregnancy commonly occurs in the fallopian tube. Ectopic pregnancy is the leading cause of maternal death in early pregnancy. The diagnosis of ectopic pregnancy is complicated by wide spectrum of clinical presentations, from asymptomatic cases to acute abdomen, and hemodynamic shock. There is considerable regional variation in its incidence. Materials and methods: Retrospective analysis of all cases of ectopic pregnancy admitted in IGIMS, Patna was done from January 2014 to December 2016. Results: The incidence of ectopic pregnancy in present study was 2.1%. Majority of patients were multigravida (94.1%) and in the age group of 25-35 years (70.4%). PID was the strongest risk factor found in 35.29%. Other risk factors were tube ligation (23%), LSCS (11.76%), history of abortion/MTP (17.64%). Commonest clinical presentation was pain abdomen (88.23%) followed...

Research paper thumbnail of Colposcopic evaluation of cervix in symptomatic women and its correlation with Pap smear. A prospective study at a tertiary care centre

Journal of Family Medicine and Primary Care, 2021

Introduction: Back in India, cervical cancer is the second most frequent cancer in women (aged 15... more Introduction: Back in India, cervical cancer is the second most frequent cancer in women (aged 15-45 years) following breast cancer, accounting for nearly 14% of all female cancer cases. The aim of this study is to yell the findings of pap smear with colposcopy and directed biopsy (if needed) and to evaluate the usefulness of colposcopy in discovering the premalignant and malignant lesions of the cervix. Methods: This is a prospective observational analysis of 150 symptomatic women attending the gynecology OPD of Indira Gandhi Institute of Medical Sciences, Patna, for a period of one year from 2019 to 2020. Assessment of symptomatic women was completed with a pap smear, colposcopy, and biopsy in selected instances. Statistical Analysis Used: MS Excel spreadsheet application, SPSS v23 (IBM Corp.), was used for data analysis. Results: The expression age (years) has been 34.68 ± 8.05. The sensitivity and specificity of pap smear were 91.7% and 45.45%, respectively, whereas the sensitivity and specificity of colposcopy were 83.3% and 72.72%, respectively, in the present study. Conclusions: Pap smear had low specificity as compared to colposcopy. Hence simultaneous use of colposcopy has shown to rise in the rate of carcinoma cervix discovery in symptomatic women.

Research paper thumbnail of Prevalence, Etiology, and Associated Symptoms of Vaginal Discharge During Pregnancy in Women Seen in a Tertiary Care Hospital in Bihar

Cureus, 2021

Introduction Vaginal discharge is the most frequent complaint during pregnancy, leading to numero... more Introduction Vaginal discharge is the most frequent complaint during pregnancy, leading to numerous complications in both the mother and fetus. Aim The goal of this study was to determine the prevalence of vaginal discharge, investigate its common infectious causes and associated symptoms during pregnancy. Methods This hospital-based cross-sectional study performed over one year evaluated 200 expectant mothers with vaginal discharge at any trimester in the Department of Obstetrics and Gynecology, in cooperation with the Microbiology section, of Indira Gandhi Institute of Medical Science, Patna. Results The mean age of the mothers was 26.84±5.51 years (range 19-42 years). Most of the patients (47.5%) were in the age group of 26-35 years, belonged to the lower socioeconomic class (67.5%), gravida 3 or more (43.5%), and presented in the third trimester. The prevalence of pathological discharge in pregnancy was 148/308 (48.05%). A positive culture was obtained in 105 (52.5%), and negati...

Research paper thumbnail of Neonatal and maternal outcome in oligohydramnios: a prospective study

International Journal of Contemporary Pediatrics, 2018

Background: Oligohydramnios presents a threat to the fetus and has been correlated with increased... more Background: Oligohydramnios presents a threat to the fetus and has been correlated with increased risk of intrauterine growth retardation, meconium aspiration syndrome, severe birth asphyxia, low APGAR scores and congenital abnormities. It is associated with perinatal morbidity and mortality and maternal morbidity in a significant number of cases. Therefore, early detection of oligohydramnios and its management is important. Aim of this study was to know the fetal and maternal outcome in oligohydramnios.Methods: 90 patients in third trimester of pregnancy with Oligohydramnios were selected after satisfying inclusion and exclusion criteria. A detailed history and examination were done. All required investigation done. Oligohydramnios confirmed by measuring Amniotic fluid index (AFI).Results: Mean maternal age-26.1 years. Incidence of oligohydramnios was more in primipara (64.4%) in our study. And operative morbidity was also more in primipara (51.7%). Most common cause of Oligohydram...