surekha salgar - Academia.edu (original) (raw)

Papers by surekha salgar

Journal of Herbal …, 2009

The aim of present work was development and evaluation of antiviral famciclovir transdermal cream... more The aim of present work was development and evaluation of antiviral famciclovir transdermal cream by using hundred times washable cow’s Ghee, as a novel permeation enhancer to increase the permeation rate of famciclovir with combination of oleic acid and terpene as a surfactant and methyl paraben and propyl paraben used as a preservative. To evaluate the formulated cream for drug content, pH, viscosity, spreadiability, extruability, rheology. To compaire and contrast the in-vitro release rate of Famciclovir from propritory cream product i.e., Famvir and prepared topical cream formulation using Franz diffusion cell with hair removed rat abdominal skin. The result of rheological studies indicate that the formulation were Non-Newtonian system because as share rate changes, the formulation shows change in viscocity. As per ICH guideline the stability study showed that cream was stable as emulsion retaining it’s biphasic integrates & globule size did not increase to considerable extent.

Journal of Pharmaceutical and BioSciences, 2018

According to their mode of action, poisons are broadly classified into three groups; these three ... more According to their mode of action, poisons are broadly classified into three groups; these three broad groups are subdivided on the basis of their effect on the body, type of composition, etc., which are available in the literature [3-5] and summarized as shown in Figure 1. Figure 1: Types of poison in clinical point of view Classification Plant toxins are classified based on their structural and chemical properties. They are grouped into alkaloids, glycosides, tannins, proteins, oxalates, enzyme inhibitors, antivitamins, phytoestrogens, volatile etheric layers, and photosensitizing substances. [1,5-8] • Alkaloids include indole alkaloids, pyrrolizidine alkaloids, tropane alkaloids, opium alkaloids, vicine and covicine alkaloids.

Natural products chemistry & research, Dec 1, 2015

The preliminary phytochemical analysis of Limonia acidissima plant parts such as bark, leaf, rind... more The preliminary phytochemical analysis of Limonia acidissima plant parts such as bark, leaf, rind, pulp and seed showed the presence of alkaloids, flavonoids, steroids, saponins, glycosides, phenols, gum and mucilage, fixed oils and fats, resins and tannins. Among the five plant parts, pulp possessed high amount of protein and the carbohydrate content was more in seeds and rind is rich was amino acid. The methanolic extracts of L. acidissima plant parts were tested against Escherichia coli and Staphylococcus aureus using disc diffusion method. The extracts from different parts showed varying degrees of antimicrobial activity.

Journal of Herbal …, 2009

The aim of present work was development and evaluation of antiviral famciclovir transdermal cream... more The aim of present work was development and evaluation of antiviral famciclovir transdermal cream by using hundred times washable cow’s Ghee, as a novel permeation enhancer to increase the permeation rate of famciclovir with combination of oleic acid and terpene as a surfactant and methyl paraben and propyl paraben used as a preservative. To evaluate the formulated cream for drug content, pH, viscosity, spreadiability, extruability, rheology. To compaire and contrast the in-vitro release rate of Famciclovir from propritory cream product i.e., Famvir and prepared topical cream formulation using Franz diffusion cell with hair removed rat abdominal skin. The result of rheological studies indicate that the formulation were Non-Newtonian system because as share rate changes, the formulation shows change in viscocity. As per ICH guideline the stability study showed that cream was stable as emulsion retaining it’s biphasic integrates & globule size did not increase to considerable extent.

Journal of Pharmaceutical and BioSciences, 2018

According to their mode of action, poisons are broadly classified into three groups; these three ... more According to their mode of action, poisons are broadly classified into three groups; these three broad groups are subdivided on the basis of their effect on the body, type of composition, etc., which are available in the literature [3-5] and summarized as shown in Figure 1. Figure 1: Types of poison in clinical point of view Classification Plant toxins are classified based on their structural and chemical properties. They are grouped into alkaloids, glycosides, tannins, proteins, oxalates, enzyme inhibitors, antivitamins, phytoestrogens, volatile etheric layers, and photosensitizing substances. [1,5-8] • Alkaloids include indole alkaloids, pyrrolizidine alkaloids, tropane alkaloids, opium alkaloids, vicine and covicine alkaloids.

Natural products chemistry & research, Dec 1, 2015

The preliminary phytochemical analysis of Limonia acidissima plant parts such as bark, leaf, rind... more The preliminary phytochemical analysis of Limonia acidissima plant parts such as bark, leaf, rind, pulp and seed showed the presence of alkaloids, flavonoids, steroids, saponins, glycosides, phenols, gum and mucilage, fixed oils and fats, resins and tannins. Among the five plant parts, pulp possessed high amount of protein and the carbohydrate content was more in seeds and rind is rich was amino acid. The methanolic extracts of L. acidissima plant parts were tested against Escherichia coli and Staphylococcus aureus using disc diffusion method. The extracts from different parts showed varying degrees of antimicrobial activity.