swapnajeet sahoo - Academia.edu (original) (raw)
Papers by swapnajeet sahoo
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, Nov 30, 2016
Apart from sleep wake disorders, nowadays, modafinil is being prescribed for several psychiatric ... more Apart from sleep wake disorders, nowadays, modafinil is being prescribed for several psychiatric disorders including depression. Despite being reported as to be having very low abuse potential, cases of modafinil dependence had come to the limelight. In this case report, we describe a 35 year old man with bipolar affective disorder while in remission who developed modafinil dependence and later on, had hypersexuality when he increased the dose of modafinil from 400 to 1,000 mg/day. Existing literature suggests that modafinil when taken above prescribed doses can cause many side effects ranging from nausea, vomiting to psychotic exacerbation and mania. However, hypersexuality as a side effect of modafinil overuse is not commonly seen. The exact pathophysiological mechanism of modafinil induced hypersexuality is not clear. Clinicians should be aware of possibility of modafinil leading to dependence and this rare significant side effect of modafinil.
Journal of geriatric mental health, 2016
The Journal of Obstetrics and Gynecology of India
In this article, the author name Rinnie Brar was incorrectly written as Rinne Brar.
Journal of geriatric mental health, 2017
Psychotic symptoms are not uncommon in patients with Parkinson's disease (PD). Several studie... more Psychotic symptoms are not uncommon in patients with Parkinson's disease (PD). Several studies have evaluated the prevalence of psychotic symptoms in PD. Psychosis in PD can either occur independently or due to the effect of dopaminergic antiparkinsonian drugs or as a part of behavioral and psychological symptoms of dementia with PD. Often, it is difficult to manage psychosis in PD as there are very few pharmacological agents which can be used with relative safety. Effective management includes early identification of symptoms, ruling out other differential diagnoses, using appropriate psychopharmacological agents along with proper psychoeducation, and applying nonpharmacological strategies. In this report, we report the case of an 84-year-old woman with PD who developed dementia and psychosis during her illness and discuss the various challenges in managing psychosis in patients with PD.
Asian Journal of Psychiatry, 2020
This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Asian Journal of Psychiatry, Aug 1, 2019
Journal of Ect, Aug 12, 2021
Industrial Psychiatry Journal, Jun 28, 2023
ABSTRACT There is good evidence to suggest that high prevalence of depression and anxiety in the ... more ABSTRACT There is good evidence to suggest that high prevalence of depression and anxiety in the postpartum period. However, very few studies have focused on antenatal depression and anxiety disorders and their associated risk factors. Further, there are only a handful of studies from India on common antenatal mental health disorders. With this background, we reviewed the existing evidence on antenatal depression and anxiety from the studies conducted in Indian pregnant women during the antenatal period and to explore the associated risk factors. All the major databases were searched systematically for English language studies on prevalence and risk factors for antenatal depression and anxiety in Indian pregnant females, published during the period January 2000 to May 2022. Quality assessment of studies was done with the modified version of Newcastle Ottawa Scale for cross-sectional studies. We found the overall prevalence of antenatal depression was ranged from 3.8% to 65% and antenatal anxiety from 13 to 55%. The most relevant risk factors associated with antenatal depression and anxiety during pregnancy were preference to have a male child, intimate partner violence, history of abortions, marital conflict, poor relationship with the husband/in-laws and lack of social support. To conclude, the systematic review suggests that depressive and anxiety disorders are quite common in Indian pregnant women in antepartum period with varying prevalence depending on various settings and scales used. Steps should be taken to promote obstetricians for regular mental health screening during the antenatal visits and prompt referral to mental health professionals when suspected.
Lupus, May 19, 2023
Background Systemic Lupus Erythematosus (SLE) is an autoimmune disease with multiorgan involvemen... more Background Systemic Lupus Erythematosus (SLE) is an autoimmune disease with multiorgan involvement presenting with a myriad of symptoms, including neuropsychiatric symptoms. Although many studies have evaluated screening questionnaires based psychiatric morbidity, very few studies have used contemporary diagnostic criteria. Objective This study aimed to evaluate the prevalence of psychiatric disorders in patients with SLE admitted to a tertiary care hospital. Methods A total of 79 patients diagnosed with SLE for at least for 1 year, who were not in delirium were assessed by a qualified psychiatrist for psychiatric morbidity as per the International Classification of Diseases, 10th Revision (ICD-10) criteria. Additionally, these patients were assessed on Patient Health Questionnaire-9 (PHQ-9) item version, Patient Health Questionnaire-15 (PHQ-15) item version, Generalized Anxiety Disorder-7 item scale and Montreal Cognitive Assessment (MoCA). Results 51% ( n = 40) of the participants were diagnosed with a psychiatric diagnosis, with depressive disorders being the most common, seen in 36.7% ( n = 29) of the participants. Additionally, 10% ( n = 8) participants were diagnosed with adjustment disorder and 2.5% ( n = 2) were diagnosed with anxiety (not otherwise specified). Only one patient was diagnosed with organic psychosis. On PHQ-9, 39.8% ( n = 33) were diagnosed with depression. 44.3% ( n = 35) expressed death wishes and/or suicidal ideations. On PHQ-15, 17.7% ( n = 14) of the participants scored for severe somatic distress (score >15). On GAD-7, 55.7% ( n = 44) screened positive for anxiety symptoms, but only 7.6% ( n = ) had a score of 15 or more to indicate severe anxiety. Nearly half ( n = 43; 52%) of the participants also had cognitive impairment as assessed on MoCA, with 13.3% ( n = 11) of the participants having scores indicating severe dementia. Conclusions Patients with SLE have a high prevalence of psychiatric comorbidities and should be routinely screened for psychiatric morbidity. They should be appropriately treated, to improve the overall treatment outcomes.
International Journal of Social Psychiatry, May 1, 2023
Asian Journal of Psychiatry, 2020
Students of a university hospital were assessed in 2007 and later in 2013 to determine the preval... more Students of a university hospital were assessed in 2007 and later in 2013 to determine the prevalence of metabolic syndrome. Statistical analysis was done with SPSS version 17.0. A total of 213 students were evaluated in both 2007 and 2013 (48.3 % women and 51.7 % men). The diagnosis of overweight and obesity increased from 24.9 to 37.1 % (p < 0.05), central obesity from 17.8 to 28.6 % (p < 0.05), and prevalence of metabolic syndrome from 9.8 to 14.5 % (p ≥ 0.05); up to 20 % in male gender. It is important to implement programs for early diagnosis of metabolic syndrome.
Indian Journal of Psychiatry, May 1, 2023
Journal of Psychiatrist's Association of Nepal, Sep 18, 2020
Introduction: Nepal entered into a lockdown mode since 24th March 2020 to control the spread of C... more Introduction: Nepal entered into a lockdown mode since 24th March 2020 to control the spread of COVID-19 infection. Our aim was to evaluate the mental and behavioural impact of lockdown due to COVID-19 pandemic on the general public of Nepal in terms of the point prevalence of sadness, anxiety, feelings and relationship issues due to lockdown. Material And Method: It was a web-based cross-sectional survey conducted by using the Survey Monkey platform during 8th April 2020 and 29th April 2020. The link generated was circulated on Whatsapp platforms. Self-designed clinical profile was made to assess different feelings, leisure activities and relationship changes with family members that are not assessed using scale. The survey link was circulated starting from 8th April 2020 and was closed on 29th April 2020. Results: Of the 142 participants about 35.9% reported being sad, 28.2% had anxiety and about 46.5% of the participants felt lonely. Fear of death (60.6%) and getting infected with corona (52.1%) were the most common stress. Most of them were involved in sexual activities (67.6%) and reading books (42.3%) during lockdown. Some (14.8% and 18.3%) reported marked improvement in relationships with parents and children respectively. Conclusion: The present survey suggests that substantial proportion of the population do not report change in relationship despite reporting sadness, loneliness and change in daily activities. Therefore, social relationship and brotherhood need to be advised in addition to minimising emotional distancing during awareness programs related to COVID-19.
Indian Journal of Psychiatry, 2022
Context: Telepsychiatry is being practiced in India for many years but was formalized only in 202... more Context: Telepsychiatry is being practiced in India for many years but was formalized only in 2020. It has many advantages and disadvantages. Aims: This study aimed to understand the perceived advantages and disadvantages of telepsychiatry practices in India. Settings and Design: An online survey with ethics approval by the Indian Psychiatric Society (IPS) Ethics Review Board. All psychiatrists who are members of the IPS and whose email address was available with the society were sent the survey link by email. Methodology: Information about existing telepsychiatry consultation practices in India and perception of advantages and disadvantages by the practitioners were collected between June and July 2020. Statistical Analysis: Frequency, percentages, mean, and standard deviation were calculated. Results: Responses by 340 responders were analyzed. Majority of the responders felt that telepsychiatry would provide easy accessibility to mental health services (n = 283, 83.24%) and would lead to less exposure to infections (n = 222, 65.29%). Half of the responders (n = 177, 52.06%) felt that there would be an increased doctor shopping resulting in poor care and nearly three-fourth (n = 245, 72.06%) felt that mental health professionals would fall into a problem while dealing with a suicidal or a homicidal patient. Some expressed that the inability to do physical and central nervous system examinations could lead to missing out comorbidities. About one-third (n = 117, 36.56%) felt that the patient recording the consultation would be a legal issue. Conclusions: This online survey showed that psychiatrists perceive many advantages and some disadvantages in practicing telepsychiatry.
Indian Journal of Psychiatry, 2019
Research Question: Do patients with dual diagnosis (DD) with an early initiation of substance use... more Research Question: Do patients with dual diagnosis (DD) with an early initiation of substance use and subsequent early onset substance use disorder (EOS) differ from those with late onset substance use disorder (LOS) regarding characteristics, sex-related risk behaviors, course, and outcome? Objectives: The aim is to study EOS and LOS groups of patients with DD attending a treatment center with regard to clinical characteristics, type of psychiatric disorders, risk behaviors, and short-term outcome. Materials and Methods: Retrospective chart review of patients diagnosed with DD (n = 307) with regard to the above variables. Diagnoses of both substance use disorders (SUDs) and psychiatric disorders were made by qualified psychiatrists as per the International Classification of Diseases, 10th revision. Results: Among 307 participants with DD, 100 were in EOS group (onset of SUD before 18 years of age as assessed clinically) and 207 in LOS group. Cannabis as the primary substance was more prevalent in the EOS (30%) than that of the LOS group (12%). Psychotic disorders were more prevalent in the EOS group (41%) followed by mood disorders (30%), while the reverse was true in the LOS group (27.5% and 56.5%, respectively). When compared to the LOS group, the EOS group had higher number of psychiatric admissions, reported higher prevalence of risky sexual behaviors (unprotected sexual intercourse, multiple sexual partners, and history of sexual intercourse with commercial sex workers), showed poorer treatment adherence, and worse outcome regarding both psychiatric disorder and SUD (all differences significant at P < 0.05). Conclusions: DD patients differ significantly based on the age of onset of substance use. These may have therapeutic and management implications.
Routledge eBooks, Sep 29, 2022
Archives of mental health, 2022
Indian Journal of Psychiatry
Journal of Geriatric Mental Health
Innovations in clinical neuroscience, Jan 3, 2023
Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, Nov 30, 2016
Apart from sleep wake disorders, nowadays, modafinil is being prescribed for several psychiatric ... more Apart from sleep wake disorders, nowadays, modafinil is being prescribed for several psychiatric disorders including depression. Despite being reported as to be having very low abuse potential, cases of modafinil dependence had come to the limelight. In this case report, we describe a 35 year old man with bipolar affective disorder while in remission who developed modafinil dependence and later on, had hypersexuality when he increased the dose of modafinil from 400 to 1,000 mg/day. Existing literature suggests that modafinil when taken above prescribed doses can cause many side effects ranging from nausea, vomiting to psychotic exacerbation and mania. However, hypersexuality as a side effect of modafinil overuse is not commonly seen. The exact pathophysiological mechanism of modafinil induced hypersexuality is not clear. Clinicians should be aware of possibility of modafinil leading to dependence and this rare significant side effect of modafinil.
Journal of geriatric mental health, 2016
The Journal of Obstetrics and Gynecology of India
In this article, the author name Rinnie Brar was incorrectly written as Rinne Brar.
Journal of geriatric mental health, 2017
Psychotic symptoms are not uncommon in patients with Parkinson's disease (PD). Several studie... more Psychotic symptoms are not uncommon in patients with Parkinson's disease (PD). Several studies have evaluated the prevalence of psychotic symptoms in PD. Psychosis in PD can either occur independently or due to the effect of dopaminergic antiparkinsonian drugs or as a part of behavioral and psychological symptoms of dementia with PD. Often, it is difficult to manage psychosis in PD as there are very few pharmacological agents which can be used with relative safety. Effective management includes early identification of symptoms, ruling out other differential diagnoses, using appropriate psychopharmacological agents along with proper psychoeducation, and applying nonpharmacological strategies. In this report, we report the case of an 84-year-old woman with PD who developed dementia and psychosis during her illness and discuss the various challenges in managing psychosis in patients with PD.
Asian Journal of Psychiatry, 2020
This is a PDF file of an article that has undergone enhancements after acceptance, such as the ad... more This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
Asian Journal of Psychiatry, Aug 1, 2019
Journal of Ect, Aug 12, 2021
Industrial Psychiatry Journal, Jun 28, 2023
ABSTRACT There is good evidence to suggest that high prevalence of depression and anxiety in the ... more ABSTRACT There is good evidence to suggest that high prevalence of depression and anxiety in the postpartum period. However, very few studies have focused on antenatal depression and anxiety disorders and their associated risk factors. Further, there are only a handful of studies from India on common antenatal mental health disorders. With this background, we reviewed the existing evidence on antenatal depression and anxiety from the studies conducted in Indian pregnant women during the antenatal period and to explore the associated risk factors. All the major databases were searched systematically for English language studies on prevalence and risk factors for antenatal depression and anxiety in Indian pregnant females, published during the period January 2000 to May 2022. Quality assessment of studies was done with the modified version of Newcastle Ottawa Scale for cross-sectional studies. We found the overall prevalence of antenatal depression was ranged from 3.8% to 65% and antenatal anxiety from 13 to 55%. The most relevant risk factors associated with antenatal depression and anxiety during pregnancy were preference to have a male child, intimate partner violence, history of abortions, marital conflict, poor relationship with the husband/in-laws and lack of social support. To conclude, the systematic review suggests that depressive and anxiety disorders are quite common in Indian pregnant women in antepartum period with varying prevalence depending on various settings and scales used. Steps should be taken to promote obstetricians for regular mental health screening during the antenatal visits and prompt referral to mental health professionals when suspected.
Lupus, May 19, 2023
Background Systemic Lupus Erythematosus (SLE) is an autoimmune disease with multiorgan involvemen... more Background Systemic Lupus Erythematosus (SLE) is an autoimmune disease with multiorgan involvement presenting with a myriad of symptoms, including neuropsychiatric symptoms. Although many studies have evaluated screening questionnaires based psychiatric morbidity, very few studies have used contemporary diagnostic criteria. Objective This study aimed to evaluate the prevalence of psychiatric disorders in patients with SLE admitted to a tertiary care hospital. Methods A total of 79 patients diagnosed with SLE for at least for 1 year, who were not in delirium were assessed by a qualified psychiatrist for psychiatric morbidity as per the International Classification of Diseases, 10th Revision (ICD-10) criteria. Additionally, these patients were assessed on Patient Health Questionnaire-9 (PHQ-9) item version, Patient Health Questionnaire-15 (PHQ-15) item version, Generalized Anxiety Disorder-7 item scale and Montreal Cognitive Assessment (MoCA). Results 51% ( n = 40) of the participants were diagnosed with a psychiatric diagnosis, with depressive disorders being the most common, seen in 36.7% ( n = 29) of the participants. Additionally, 10% ( n = 8) participants were diagnosed with adjustment disorder and 2.5% ( n = 2) were diagnosed with anxiety (not otherwise specified). Only one patient was diagnosed with organic psychosis. On PHQ-9, 39.8% ( n = 33) were diagnosed with depression. 44.3% ( n = 35) expressed death wishes and/or suicidal ideations. On PHQ-15, 17.7% ( n = 14) of the participants scored for severe somatic distress (score >15). On GAD-7, 55.7% ( n = 44) screened positive for anxiety symptoms, but only 7.6% ( n = ) had a score of 15 or more to indicate severe anxiety. Nearly half ( n = 43; 52%) of the participants also had cognitive impairment as assessed on MoCA, with 13.3% ( n = 11) of the participants having scores indicating severe dementia. Conclusions Patients with SLE have a high prevalence of psychiatric comorbidities and should be routinely screened for psychiatric morbidity. They should be appropriately treated, to improve the overall treatment outcomes.
International Journal of Social Psychiatry, May 1, 2023
Asian Journal of Psychiatry, 2020
Students of a university hospital were assessed in 2007 and later in 2013 to determine the preval... more Students of a university hospital were assessed in 2007 and later in 2013 to determine the prevalence of metabolic syndrome. Statistical analysis was done with SPSS version 17.0. A total of 213 students were evaluated in both 2007 and 2013 (48.3 % women and 51.7 % men). The diagnosis of overweight and obesity increased from 24.9 to 37.1 % (p < 0.05), central obesity from 17.8 to 28.6 % (p < 0.05), and prevalence of metabolic syndrome from 9.8 to 14.5 % (p ≥ 0.05); up to 20 % in male gender. It is important to implement programs for early diagnosis of metabolic syndrome.
Indian Journal of Psychiatry, May 1, 2023
Journal of Psychiatrist's Association of Nepal, Sep 18, 2020
Introduction: Nepal entered into a lockdown mode since 24th March 2020 to control the spread of C... more Introduction: Nepal entered into a lockdown mode since 24th March 2020 to control the spread of COVID-19 infection. Our aim was to evaluate the mental and behavioural impact of lockdown due to COVID-19 pandemic on the general public of Nepal in terms of the point prevalence of sadness, anxiety, feelings and relationship issues due to lockdown. Material And Method: It was a web-based cross-sectional survey conducted by using the Survey Monkey platform during 8th April 2020 and 29th April 2020. The link generated was circulated on Whatsapp platforms. Self-designed clinical profile was made to assess different feelings, leisure activities and relationship changes with family members that are not assessed using scale. The survey link was circulated starting from 8th April 2020 and was closed on 29th April 2020. Results: Of the 142 participants about 35.9% reported being sad, 28.2% had anxiety and about 46.5% of the participants felt lonely. Fear of death (60.6%) and getting infected with corona (52.1%) were the most common stress. Most of them were involved in sexual activities (67.6%) and reading books (42.3%) during lockdown. Some (14.8% and 18.3%) reported marked improvement in relationships with parents and children respectively. Conclusion: The present survey suggests that substantial proportion of the population do not report change in relationship despite reporting sadness, loneliness and change in daily activities. Therefore, social relationship and brotherhood need to be advised in addition to minimising emotional distancing during awareness programs related to COVID-19.
Indian Journal of Psychiatry, 2022
Context: Telepsychiatry is being practiced in India for many years but was formalized only in 202... more Context: Telepsychiatry is being practiced in India for many years but was formalized only in 2020. It has many advantages and disadvantages. Aims: This study aimed to understand the perceived advantages and disadvantages of telepsychiatry practices in India. Settings and Design: An online survey with ethics approval by the Indian Psychiatric Society (IPS) Ethics Review Board. All psychiatrists who are members of the IPS and whose email address was available with the society were sent the survey link by email. Methodology: Information about existing telepsychiatry consultation practices in India and perception of advantages and disadvantages by the practitioners were collected between June and July 2020. Statistical Analysis: Frequency, percentages, mean, and standard deviation were calculated. Results: Responses by 340 responders were analyzed. Majority of the responders felt that telepsychiatry would provide easy accessibility to mental health services (n = 283, 83.24%) and would lead to less exposure to infections (n = 222, 65.29%). Half of the responders (n = 177, 52.06%) felt that there would be an increased doctor shopping resulting in poor care and nearly three-fourth (n = 245, 72.06%) felt that mental health professionals would fall into a problem while dealing with a suicidal or a homicidal patient. Some expressed that the inability to do physical and central nervous system examinations could lead to missing out comorbidities. About one-third (n = 117, 36.56%) felt that the patient recording the consultation would be a legal issue. Conclusions: This online survey showed that psychiatrists perceive many advantages and some disadvantages in practicing telepsychiatry.
Indian Journal of Psychiatry, 2019
Research Question: Do patients with dual diagnosis (DD) with an early initiation of substance use... more Research Question: Do patients with dual diagnosis (DD) with an early initiation of substance use and subsequent early onset substance use disorder (EOS) differ from those with late onset substance use disorder (LOS) regarding characteristics, sex-related risk behaviors, course, and outcome? Objectives: The aim is to study EOS and LOS groups of patients with DD attending a treatment center with regard to clinical characteristics, type of psychiatric disorders, risk behaviors, and short-term outcome. Materials and Methods: Retrospective chart review of patients diagnosed with DD (n = 307) with regard to the above variables. Diagnoses of both substance use disorders (SUDs) and psychiatric disorders were made by qualified psychiatrists as per the International Classification of Diseases, 10th revision. Results: Among 307 participants with DD, 100 were in EOS group (onset of SUD before 18 years of age as assessed clinically) and 207 in LOS group. Cannabis as the primary substance was more prevalent in the EOS (30%) than that of the LOS group (12%). Psychotic disorders were more prevalent in the EOS group (41%) followed by mood disorders (30%), while the reverse was true in the LOS group (27.5% and 56.5%, respectively). When compared to the LOS group, the EOS group had higher number of psychiatric admissions, reported higher prevalence of risky sexual behaviors (unprotected sexual intercourse, multiple sexual partners, and history of sexual intercourse with commercial sex workers), showed poorer treatment adherence, and worse outcome regarding both psychiatric disorder and SUD (all differences significant at P < 0.05). Conclusions: DD patients differ significantly based on the age of onset of substance use. These may have therapeutic and management implications.
Routledge eBooks, Sep 29, 2022
Archives of mental health, 2022
Indian Journal of Psychiatry
Journal of Geriatric Mental Health
Innovations in clinical neuroscience, Jan 3, 2023