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Papers by François Trompier

Research paper thumbnail of An Overview Of The Stratelec Project (Stratéole-2 Atmospheric Electricity)

HAL (Le Centre pour la Communication Scientifique Directe), May 1, 2022

Research paper thumbnail of Neutron spectra reconstruction based on an artificial neural network trained with a large built dataset

HAL (Le Centre pour la Communication Scientifique Directe), Sep 25, 2022

Research paper thumbnail of Dosimetry of a self-shielded gamma irradiator small animal whole-body irradiations: comparisons between ionisation chamber and alanine

Radiation Protection Dosimetry

Because of reproducibility and repeatability problems with reference measurements made with an io... more Because of reproducibility and repeatability problems with reference measurements made with an ionisation chamber in a self-protected GSRD1 irradiator, a comparison was made with alanine dosimetry for a whole-body mouse irradiation setup in a sterile box. The twisting of the cables in the cable duct and in the irradiator cell and the irradiation of the ionisation chamber connector are likely to have caused the problems encountered. These problems are not observed on other types of irradiators with more suitable cable passages. A difference up to 8.4% was observed between the alanine dosimetry and ionisation chamber. The influence of the number of animals in the sterile box on the whole-body dose of the animals was also evaluated with alanine and found to be <2%.

Research paper thumbnail of GPS-coupled contaminant monitors on free-ranging Chernobyl wolves challenge a fundamental assumption in exposure assessments

Environment International, 2019

Research paper thumbnail of EPR dosimetry for actual and suspected overexposures during radiotherapy treatments in Poland

Research paper thumbnail of Needs and State of the Art in Criticality Dosimetry and Dose Reconstruction Techniques for Medical Management of Criticality Accident’s Casualties

HAL (Le Centre pour la Communication Scientifique Directe), Sep 15, 2019

Research paper thumbnail of Calculation of Conversion Coefficients for Voxelized Phantoms for Criticality Accident Dosimetry

Radiation Protection Dosimetry, 2020

In the event of a criticality accident, not only the maximal doses received by the victims must b... more In the event of a criticality accident, not only the maximal doses received by the victims must be determined but it is also crucial to evaluate the doses to the different organs. With a neutron component, morphology is a key parameter in the organ dose calculation. As the simulation tools can be time consuming to proceed, especially if morphology is taken into account, for all the victims, it may be very useful to have a database of conversion coefficients that allow to obtain the organ doses from the dose measured in the dosemeter for different kinds of morphology. In this paper, we present a study performed to evaluate such conversion coefficients using voxelized anthropomorphic phantoms. These coefficients take into account two crucial parameters having an impact on the dose at the organs: the orientation of the victim in the radiation field and the morphology, that is to say the body mass index of the different victims.

Research paper thumbnail of The RENEB operational basis: complement of established biodosimetric assays

International Journal of Radiation Biology, 2016

Research paper thumbnail of Uncertainty of fast biological radiation dose assessment for emergency response scenarios

International Journal of Radiation Biology, 2016

Research paper thumbnail of Integration of new biological and physical retrospective dosimetry methods into EU emergency response plans - joint RENEB and EURADOS inter-laboratory comparisons

International journal of radiation biology, Jan 20, 2016

RENEB, 'Realising the European Network of Biodosimetry and Physical Retrospective Dosimetry,&... more RENEB, 'Realising the European Network of Biodosimetry and Physical Retrospective Dosimetry,' is a network for research and emergency response mutual assistance in biodosimetry within the EU. Within this extremely active network, a number of new dosimetry methods have recently been proposed or developed. There is a requirement to test and/or validate these candidate techniques and inter-comparison exercises are a well-established method for such validation. The authors present details of inter-comparisons of four such new methods: dicentric chromosome analysis including telomere and centromere staining; the gene expression assay carried out in whole blood; Raman spectroscopy on blood lymphocytes, and detection of radiation-induced thermoluminescent signals in glass screens taken from mobile phones. In general the results show good agreement between the laboratories and methods within the expected levels of uncertainty, and thus demonstrate that there is a lot of potential fo...

Research paper thumbnail of Medical Response to Radiological Accidents in Latin America and International Assistance

Radiation research, Apr 1, 2016

This article provides an overview of four radiological accidents in Latin America, and includes a... more This article provides an overview of four radiological accidents in Latin America, and includes a history of the events, the clinical manifestations and health consequences for the exposed individuals, the medical response based on preclinical studies and the role of the International Atomic Energy Agency (IAEA) in coordinating medical response assistance.

Research paper thumbnail of Exposition Au Rayonnement Cosmique a Bord Des Avions : Les Premiers Resultats Avec Le Systeme Sievert

Research paper thumbnail of New Therapeutical Approach in the Treatment of Severe Radiation Burn: Surgery and Local Stem Cell Therapy

Research paper thumbnail of Qualification of a numerical anthropomorphic model dedicated to radiological accidents

Research paper thumbnail of Retrospective Dosimetry after Criticality Accidents Using Low-Frequency EPR: A Study of Whole Human Teeth Irradiated in a Mixed Neutron and Gamma-Radiation Field

Research paper thumbnail of Optimisation of Recording Conditions for the Electron Paramagnetic Resonance Signal used in Dental Enamel Dosimetry

Radiation Protection Dosimetry, 2002

Optimisation of the parameters for recording the electron paramagnetic resonance (EPR) spectra of... more Optimisation of the parameters for recording the electron paramagnetic resonance (EPR) spectra of dental enamel for absorbed dose reconstruction was performed for an EMX (Bruker) spectrometer supplied with a high-sensitivity microwave cavity. Dose determination was performed using a previously developed automatic spectra processing procedure, which uses the non-linear fit of a model spectrum. The experimental error was estimated as the standard deviation of the results from the nominal doses for the set of spectra recorded for 10 samples prepared from teeth of different persons and irradiated in the dose range 0-500 mGy. The microwave power and magnetic field modulation amplitude corresponding to the minimum of dependencies of the error on these parameters were adopted as the optimal ones. For the sets of spectra recorded at optimal parameters for sample masses 100, 50 and 30 mg, the errors of dose determination were obtained as 18, 27 and 37 mGy respectively.

Research paper thumbnail of Exposure of aircraft crew to cosmic radiation: on-board intercomparison of various dosemeters

Radiation Protection Dosimetry, 2004

Owing to their professional activity, flight crews may receive a dose of some millisieverts withi... more Owing to their professional activity, flight crews may receive a dose of some millisieverts within a year; airline passengers may also be concerned. The effective dose is to be estimated using various experimental and calculation tools. The European project DOSMAX (Dosimetry of Aircrew Exposure during Solar Maximum) was initiated in 2000 extending to 2004 to complete studies over the current solar cycle during the solar maximum phase. To compare various dosemeters in real conditions simultaneously in the same radiation field, an intercomparison was organised aboard a Paris-Tokyo round-trip flight. Both passive and active detectors were used. Good agreement was observed for instruments determining the different components of the radiation field; the mean ambient dose equivalent for the round trip was 129 +/- 10 microSv. The agreement of values obtained for the total dose obtained by measurements and by calculations is very satisfying.

Research paper thumbnail of Calibration of EPR signal dose response of tooth enamel to photons: experiment and Monte Carlo simulation

Radiation Protection Dosimetry, 2004

Research paper thumbnail of Review of retrospective dosimetry techniques for external ionising radiation exposures

Radiation Protection Dosimetry, 2010

Research paper thumbnail of Secondary exposure for 73 and 200 MeV proton therapy

Radiation Protection Dosimetry, 2006

Following modifications on the beam line at the Orsay Protontherapy Center, dose measurements wer... more Following modifications on the beam line at the Orsay Protontherapy Center, dose measurements were performed in order to make a dose map in the treatment rooms and in the delimited radiation-controlled area around beam line. Measurements were performed using tissue-equivalent proportional counters and rem-counters. Analysis of TEPC single event measurements showed that high LET components (&gt;10 keV.microm(-1)) represent 90 to 99% of total dose equivalent in the treatment rooms and 50 to 90% in the controlled area and quality factors range, respectively between 2 and 15. A fast neutron component was identified in the treatment rooms, where dose equivalent rate varied between few microSv.h(-1) to some dozen of mSv.h(-1). In high-energy radiation field rem-counters underestimated TEPC values for neutron component. The variation between instruments response according to the location is linked to energetic spectrum variations and instrument characteristics.

Research paper thumbnail of An Overview Of The Stratelec Project (Stratéole-2 Atmospheric Electricity)

HAL (Le Centre pour la Communication Scientifique Directe), May 1, 2022

Research paper thumbnail of Neutron spectra reconstruction based on an artificial neural network trained with a large built dataset

HAL (Le Centre pour la Communication Scientifique Directe), Sep 25, 2022

Research paper thumbnail of Dosimetry of a self-shielded gamma irradiator small animal whole-body irradiations: comparisons between ionisation chamber and alanine

Radiation Protection Dosimetry

Because of reproducibility and repeatability problems with reference measurements made with an io... more Because of reproducibility and repeatability problems with reference measurements made with an ionisation chamber in a self-protected GSRD1 irradiator, a comparison was made with alanine dosimetry for a whole-body mouse irradiation setup in a sterile box. The twisting of the cables in the cable duct and in the irradiator cell and the irradiation of the ionisation chamber connector are likely to have caused the problems encountered. These problems are not observed on other types of irradiators with more suitable cable passages. A difference up to 8.4% was observed between the alanine dosimetry and ionisation chamber. The influence of the number of animals in the sterile box on the whole-body dose of the animals was also evaluated with alanine and found to be <2%.

Research paper thumbnail of GPS-coupled contaminant monitors on free-ranging Chernobyl wolves challenge a fundamental assumption in exposure assessments

Environment International, 2019

Research paper thumbnail of EPR dosimetry for actual and suspected overexposures during radiotherapy treatments in Poland

Research paper thumbnail of Needs and State of the Art in Criticality Dosimetry and Dose Reconstruction Techniques for Medical Management of Criticality Accident’s Casualties

HAL (Le Centre pour la Communication Scientifique Directe), Sep 15, 2019

Research paper thumbnail of Calculation of Conversion Coefficients for Voxelized Phantoms for Criticality Accident Dosimetry

Radiation Protection Dosimetry, 2020

In the event of a criticality accident, not only the maximal doses received by the victims must b... more In the event of a criticality accident, not only the maximal doses received by the victims must be determined but it is also crucial to evaluate the doses to the different organs. With a neutron component, morphology is a key parameter in the organ dose calculation. As the simulation tools can be time consuming to proceed, especially if morphology is taken into account, for all the victims, it may be very useful to have a database of conversion coefficients that allow to obtain the organ doses from the dose measured in the dosemeter for different kinds of morphology. In this paper, we present a study performed to evaluate such conversion coefficients using voxelized anthropomorphic phantoms. These coefficients take into account two crucial parameters having an impact on the dose at the organs: the orientation of the victim in the radiation field and the morphology, that is to say the body mass index of the different victims.

Research paper thumbnail of The RENEB operational basis: complement of established biodosimetric assays

International Journal of Radiation Biology, 2016

Research paper thumbnail of Uncertainty of fast biological radiation dose assessment for emergency response scenarios

International Journal of Radiation Biology, 2016

Research paper thumbnail of Integration of new biological and physical retrospective dosimetry methods into EU emergency response plans - joint RENEB and EURADOS inter-laboratory comparisons

International journal of radiation biology, Jan 20, 2016

RENEB, 'Realising the European Network of Biodosimetry and Physical Retrospective Dosimetry,&... more RENEB, 'Realising the European Network of Biodosimetry and Physical Retrospective Dosimetry,' is a network for research and emergency response mutual assistance in biodosimetry within the EU. Within this extremely active network, a number of new dosimetry methods have recently been proposed or developed. There is a requirement to test and/or validate these candidate techniques and inter-comparison exercises are a well-established method for such validation. The authors present details of inter-comparisons of four such new methods: dicentric chromosome analysis including telomere and centromere staining; the gene expression assay carried out in whole blood; Raman spectroscopy on blood lymphocytes, and detection of radiation-induced thermoluminescent signals in glass screens taken from mobile phones. In general the results show good agreement between the laboratories and methods within the expected levels of uncertainty, and thus demonstrate that there is a lot of potential fo...

Research paper thumbnail of Medical Response to Radiological Accidents in Latin America and International Assistance

Radiation research, Apr 1, 2016

This article provides an overview of four radiological accidents in Latin America, and includes a... more This article provides an overview of four radiological accidents in Latin America, and includes a history of the events, the clinical manifestations and health consequences for the exposed individuals, the medical response based on preclinical studies and the role of the International Atomic Energy Agency (IAEA) in coordinating medical response assistance.

Research paper thumbnail of Exposition Au Rayonnement Cosmique a Bord Des Avions : Les Premiers Resultats Avec Le Systeme Sievert

Research paper thumbnail of New Therapeutical Approach in the Treatment of Severe Radiation Burn: Surgery and Local Stem Cell Therapy

Research paper thumbnail of Qualification of a numerical anthropomorphic model dedicated to radiological accidents

Research paper thumbnail of Retrospective Dosimetry after Criticality Accidents Using Low-Frequency EPR: A Study of Whole Human Teeth Irradiated in a Mixed Neutron and Gamma-Radiation Field

Research paper thumbnail of Optimisation of Recording Conditions for the Electron Paramagnetic Resonance Signal used in Dental Enamel Dosimetry

Radiation Protection Dosimetry, 2002

Optimisation of the parameters for recording the electron paramagnetic resonance (EPR) spectra of... more Optimisation of the parameters for recording the electron paramagnetic resonance (EPR) spectra of dental enamel for absorbed dose reconstruction was performed for an EMX (Bruker) spectrometer supplied with a high-sensitivity microwave cavity. Dose determination was performed using a previously developed automatic spectra processing procedure, which uses the non-linear fit of a model spectrum. The experimental error was estimated as the standard deviation of the results from the nominal doses for the set of spectra recorded for 10 samples prepared from teeth of different persons and irradiated in the dose range 0-500 mGy. The microwave power and magnetic field modulation amplitude corresponding to the minimum of dependencies of the error on these parameters were adopted as the optimal ones. For the sets of spectra recorded at optimal parameters for sample masses 100, 50 and 30 mg, the errors of dose determination were obtained as 18, 27 and 37 mGy respectively.

Research paper thumbnail of Exposure of aircraft crew to cosmic radiation: on-board intercomparison of various dosemeters

Radiation Protection Dosimetry, 2004

Owing to their professional activity, flight crews may receive a dose of some millisieverts withi... more Owing to their professional activity, flight crews may receive a dose of some millisieverts within a year; airline passengers may also be concerned. The effective dose is to be estimated using various experimental and calculation tools. The European project DOSMAX (Dosimetry of Aircrew Exposure during Solar Maximum) was initiated in 2000 extending to 2004 to complete studies over the current solar cycle during the solar maximum phase. To compare various dosemeters in real conditions simultaneously in the same radiation field, an intercomparison was organised aboard a Paris-Tokyo round-trip flight. Both passive and active detectors were used. Good agreement was observed for instruments determining the different components of the radiation field; the mean ambient dose equivalent for the round trip was 129 +/- 10 microSv. The agreement of values obtained for the total dose obtained by measurements and by calculations is very satisfying.

Research paper thumbnail of Calibration of EPR signal dose response of tooth enamel to photons: experiment and Monte Carlo simulation

Radiation Protection Dosimetry, 2004

Research paper thumbnail of Review of retrospective dosimetry techniques for external ionising radiation exposures

Radiation Protection Dosimetry, 2010

Research paper thumbnail of Secondary exposure for 73 and 200 MeV proton therapy

Radiation Protection Dosimetry, 2006

Following modifications on the beam line at the Orsay Protontherapy Center, dose measurements wer... more Following modifications on the beam line at the Orsay Protontherapy Center, dose measurements were performed in order to make a dose map in the treatment rooms and in the delimited radiation-controlled area around beam line. Measurements were performed using tissue-equivalent proportional counters and rem-counters. Analysis of TEPC single event measurements showed that high LET components (&gt;10 keV.microm(-1)) represent 90 to 99% of total dose equivalent in the treatment rooms and 50 to 90% in the controlled area and quality factors range, respectively between 2 and 15. A fast neutron component was identified in the treatment rooms, where dose equivalent rate varied between few microSv.h(-1) to some dozen of mSv.h(-1). In high-energy radiation field rem-counters underestimated TEPC values for neutron component. The variation between instruments response according to the location is linked to energetic spectrum variations and instrument characteristics.