Hossein Mohammad-Rabei | Shahid Beheshti university of Medical siencses (original) (raw)

Papers by Hossein Mohammad-Rabei

$Research paper thumbnail of Topography versus non-topography-guided photorefractive keratectomy with corneal cross-linking variations in keratoconus$

International Journal of Ophthalmology, May 18, 2022

BMC Ophthalmology, Jul 14, 2023

Background To determine the effect of ketorolac tromethamine 0.5% in preventing post-phacoemulsif... more Background To determine the effect of ketorolac tromethamine 0.5% in preventing post-phacoemulsification macular thickening. This randomized clinical trial. patients randomized 1:1 to receive either topical ketorolac three times a day or a placebo. Methods A total of 101 eyes of 101 diabetic patients who were scheduled for phacoemulsification and had normal macular contour and thickness enrolled consecutively. The topical ketorolac and placebo were prescribed on the day before surgery and continued up to 4 weeks after surgery. Patients with proliferative diabetic retinopathy, a history of intravitreal injection in less than three months, a history of macular photocoagulation in less than 6 months, and any other concomitant ocular pathologies were excluded. Central macular thickness (CMT) and best corrected visual acuity (BCVA) was recorded in the follow-ups of 6, 12, and 24 weeks after the surgery and compared with the controls. Results 49 eyes in the case group and 52 eyes in the control group were analyzed. Mean BCVA was significantly improved in both groups at all follow-ups (P < 0.001 for all). There was no statistically significant difference regarding the BCVA in different time points except week 12 (P = 0.028) among the study group. In the case and control groups, CMT was increased at all follow-ups (P < 0.05). There was no statistically significant difference when comparing the two groups regarding the mean of CMT at any time point postoperatively (P > 0.05 for all). Conclusion Based on our findings, topical ketorolac tromethamine 0.5% is not effective in the prevention of postphacoemulsification macular thickening in diabetic patients. Trail registration The study protocol was registered into www.clinicaltrial.gov with the RCT registration number NCT03551808. (2018/06/11) Clinical trial registration number NCT03551808.

Research Square (Research Square), Mar 22, 2023

Background: To determine the prophylactic effect of ketorolac tromethamine0.5% in preventing post... more Background: To determine the prophylactic effect of ketorolac tromethamine0.5% in preventing post-phacoemulsi cation macular thickening. This randomized clinical trial. patients randomized 1:1 to receive either topical ketorolac three times a day or a placebo. Methods: A total of 101 eyes of 101 diabetic patients who were scheduled for phacoemulsi cation and had normal macular contour and thickness enrolled consecutively. The topical ketorolac and placebo were prescribed on the day before surgery and continued up to 4 weeks after surgery. Patients with proliferative diabetic retinopathy, a history of intravitreal injection in less than three months, a history of macular photocoagulation in less than 6 months, and any other concomitant ocular pathologies were excluded. Central macular thickness (CMT) and best corrected visual acuity (BCVA) was recorded in the follow-ups of 6, 12, and 24 weeks after the surgery and compared with the controls. Results: 49 eyes in the case group and 52 eyes in the control group were analyzed.Mean BCVA was signi cantly improved in both groups at all follow-ups (P<0.001 for all). There was no statistically signi cant difference regarding the BCVA in different time points except week 12 (P=0.028) among the study group. In the case and control groups, CMT was increased at all followups (P<0.05). There was no statistically signi cant difference when comparing the two groups regarding the mean of CMT at any time point postoperatively (P>0.05 for all). Conclusion: Based on our ndings, topical ketorolac tromethamine 0.5% is not effective in the prevention of postphacoemulsi cation macular thickening in diabetic patients. Trail registration: The study protocol was registered into www.clinicaltrial.gov with the RCT registration number NCT03551808.

Bina Journal of Ophthalmology, Jan 15, 2006

Bina Journal of …, 2010

Purpose: To compare keratocyte density between normal and keratoconic corneas in non-contact lens... more Purpose: To compare keratocyte density between normal and keratoconic corneas in non-contact lens wearers. Methods: Confocal scanning was performed on 39 corneas of 26 patients with keratoconus and 28 corneas of 14 normal control subjects. None of the cases were ...

Bina Journal of Ophthalmology, Jan 10, 2014

To evaluate the corneal endothelial cell density and Polymegathism one year after laser assisted ... more To evaluate the corneal endothelial cell density and Polymegathism one year after laser assisted keratomileusis using mitomycin C. Methods: One hundred and three eyes from 52 patients who underwent laser assisted sub-epithelial keratomileusis using mitomycin C 0.02% for 30 seconds entered this study. Corneal endothelial cells were evaluated using specular microscopy before and one year after the surgery considering endothelial cell density and polymegathism. Also the corneal thickness was measured before and one year after the surgery. Results: The mean endothelial cell density before surgery was 2870±368/mm 2 , which changed to 2828±300/mm 2 one year after the surgery (P=0.182). Polymegathism was 24±7 before the surgery, which changed to 25±7 one year after the surgery (P=0.039). The average stromal ablation dept was 65 micron (22 to 131 micron) and the remaining corneal thickness one year after the surgery was 488±42 micron (405 to 567 micron) (p<0.001). Conclusion: Using mitomycin C (0, 02% for 30 seconds) during the laser assisted sub-epithelial keratomileusis did not significantly change the corneal endothelial cell density one year after the surgery but the change in polymegathism was significant.

Cardiocore, 2010

Guías de prá ctica clínica para la prevenció n, diagnó stico y tratamiento de la endocarditis inf... more Guías de prá ctica clínica para la prevenció n, diagnó stico y tratamiento de la endocarditis infecciosa. Nueva versió n 2009 Clinical practice guidelines on the prevention, diagnosis and treatment of infective endocarditis. New version 2009

Journal of Ophthalmic and Vision Research

Purpose: To determine associated factors for keratoconus (KCN) in the Iranian population. Methods... more Purpose: To determine associated factors for keratoconus (KCN) in the Iranian population. Methods: In this retrospective case-control study, 100 KCN patients and 200 age- and sex-matched individuals, who were either candidates for photorefractive keratectomy or healthy referrals from the Torfeh Eye Hospital, were included as the case and control groups, respectively. KCN patients were all registered at the Iranian National Registry of Keratoconus (KCNReg®). Demographic characteristics, patients’ symptoms and their habits, as well as systemic and ocular disorders were documented. Clinical examinations included best corrected visual acuity (BCVA) and refractive error measurements, biomicroscopic examination, and corneal imaging. Results: In this case group, the frequency of mild, moderate, and severe KCN was 38%, 28%, and 34%, respectively. Parental consanguinity (odds ratio [OR] = 1.758, P = 0.029), positive familial history in patients’ first degree (OR = 12.533, P < 0.001) and s...

Purpose: To evaluate topographic corneal changes in relatives of patients with Keratoconus (KCN )... more Purpose: To evaluate topographic corneal changes in relatives of patients with Keratoconus (KCN ) Methods: As a prospective study 300 eyes of 150 relatives of 45 KCN patients were evaluated. Complete slit lamp examination, refraction, and then Corneal Topography was performed for all the eyes. The topographic indices for diagnosis of Keratoconus were based on Rabinowitz criteria. Results: The study included 84 (56%) female and 66 (44%) male subjects. Mean age was 32.4±15 years (range: 16-83). KCN was diagnosed in 14% of the subjects and other 7.3% as KCN suspect. The overall prevalence of astigmatism was 58% including 42.1% in the KCN group , 66.7% in the KCN suspect group, and 49.6% in the normal group. Thirty one eyes had high regular astigmatism ( >1.5 diopters) including 17 (54.8%) in the KCN, and 14 (45.2%) in the normal groups. Oblique astigmatism was seen in 33 eyes(11%) including 34.2% in the KCN, 47.6% in the KCN suspect, and 4.6% in the normal groups. Conclusion: Relati...

Purpose: To evaluate the effect of Isotretinoin on tear secretion among patients with Acne Vulgar... more Purpose: To evaluate the effect of Isotretinoin on tear secretion among patients with Acne Vulgaris. Patients and Methods: In this prospective study patients candidate for isotretinoin (Accutane) therapy for two months underwent complete eye examination. The best corrected visual acuity was measures and slit lamp examination of anterior segment, evaluation of tear break-up-time and Schirmer’s test were performed. The post surgical examination carried out two months post therapy consisted of complete eye examination and evaluation of dry eye level. Findings: Thirty nine patients entered the study. There were 5 patients complaining of eye strain before treatment, which rose to 19 patients after Isotretinoin therapy (p<0.001). The tear break up time was 13±1 seconds which decreased to 9±1 (p<0.001) after therapy and the Schirmer’s test mean reading was 22±2mm, which was reduced to 18±5 (p<0.001) after treatment. There were 4 patients with blepharitis before the treatment which...

$Research paper thumbnail of Refractive Dilemma$

$Research paper thumbnail of Effect of mitomycin-C on corneal endothelial cell parameters after refractive surface ablation procedures$

Medical hypothesis discovery and innovation in ophthalmology, 2022

Background: The effect of mitomycin-C (MMC) on the reduction of endothelial cell count in the cor... more Background: The effect of mitomycin-C (MMC) on the reduction of endothelial cell count in the cornea remains controversial. We aimed to evaluate the effect of MMC on corneal endothelial cell parameters after refractive surface ablation procedures, including photorefractive keratectomy (PRK) and laser epithelial keratomileusis (LASEK). Methods: In this interventional, comparative, follow-up study, 342 eyes of 171 patients were followed up for 6 months. Patients undergoing PRK or LASEK were included and were divided into two groups: group one (188 eyes of 94 patients) with an ablation depth of ? 65 µm and who received intraoperative 0.02% MMC for 30 s, and group two (154 eyes of 77 patients) with an ablation depth of < 65 µm and who received balanced salt solution for 30 s. Changes in endothelial cell density (ECD), central corneal thickness (CCT), coefficient of variation (CV), and hexagonality values were compared between the groups at 3 and 6 months after surgery. Results: The m...

International Journal of Ophthalmology, 2021

Coronavirus disease 2019 (COVID-19) pandemic has caused significant changes in ophthalmic practic... more Coronavirus disease 2019 (COVID-19) pandemic has caused significant changes in ophthalmic practice. The initial strategy of strict restriction of elective activities has been replaced with various guidelines to revitalize ophthalmic procedures considering the new safety concerns. In this manuscript, we reviewed recent recommendations for ophthalmic practice in different fields of ophthalmology during the COVID-19 pandemic.

Purpose: To evaluate the corneal endothelial cell density and Polymegathism after laser assisted ... more Purpose: To evaluate the corneal endothelial cell density and Polymegathism after laser assisted keratomileusis with mitomycin C. Patients and Methods: One hundred and three eyes from 52 patients undergoing laser assisted sub-epithelial keratomileusis using mitomycin-C 0.02% for 30 seconds entered this study. Specular microscopy was utilized to study the corneal endothelial cells before and one year after the surgery to evaluate the endothelial cell density and polymegathism. The corneal thickness was measured before and one year after the surgery. Results: The mean endothelial cell density before surgery was 2870±368/mm2, which changed to 2828±300/mm2 one year after the surgery (P=0.182). Endothelial cell size variation coefficient was 24±7 before the surgery, which changed to 25±7 one year after the surgery (P=0.039). The average stromal ablation dept was 65 micron (22 to 131 micron) and the remaining corneal thickness one year after the surgery was 488±42 micron (405 to 567 micro...

Purpose: To evaluate the efficacy and safety of Ahmed glaucoma valve (AGV) implantation for glauc... more Purpose: To evaluate the efficacy and safety of Ahmed glaucoma valve (AGV) implantation for glaucomatous eyes in short, intermediate, and long term follow up periods.Patients and Methods: In this retrospective study 76 eyes of 76 patients who underwent AGV insertion in Imam Hossein Medical Center, Tehran, Iran, between January 2008 and March 2017 with at least three years of followup were included. At each visit complete ophthalmic examination was performed and the success rate of surgery was assessed. Surgical success was defined as 5 ≤ IOP ≤ 21 mmHg and at least 20 % reduction in IOP without any glaucoma medication (complete success), or with the use of anti glaucoma medication (qualified success). The sum of complete and qualified success was reported as cumulative success.Results: The mean age of patients was 53.18 ± 16.92 years and the mean duration of follow up was 3.27 ± 2.36 years (range: 1-5 years). The complete surgical success rate was 20 % at 1 year, 18 % at ...

Purpose: To study the possible effects of occupation vibration on human retina using electroretin... more Purpose: To study the possible effects of occupation vibration on human retina using electroretinogram. Patients and Methods: Fifty workers from a segment of a textile factory with machinery creating high levels of vibration were selected. The workers had at least 6 years history of working in the factory segment where high vibrating machines were operating. The amplitude and latency of electroretinogram b-wave peak and amplitude was compared between these selected workers and 50 age and sex matched controls from other sections of the factory. Results: The mean age was 27.5 + 1.741 years and 27.28 + 1.641 years in the case and control groups respectively. There was statistically significant lower mean amplitude of electroretinogram b-wave peak in the case group compared to the control group (P < 0.001). Also higher mean latency of the electroretinogram b-wave in the case group compared to the control group was observed (P < 0.001) Conclusion: Occupational vibration might have ...

Purpose: Blindness is a catastrophic complication of surgeries performed in prone position which ... more Purpose: Blindness is a catastrophic complication of surgeries performed in prone position which occurs mainly due to hemodynamic alterations and the relevant effects on optic nerve perfusion. In this study, we compared the effects of Propofol and Isoflurane on intraocular pressure among patients undergoing lumbar disk surgery. Patients and Methods: In this randomized clinical trial, 60 patients who were candidates for lumbar disk surgery were randomly assigned into two groups: Propofol and Isoflurane groups. Intraocular Pressure was measured before and after induction of anesthesia in supine position, immediately after prone positioning of the patient and at the end of operation in prone position and also after turning the patients back to supine position. Mean arterial pressure, systolic and diastolic blood pressure and heart rates were also assessed. Result: The baseline Mean Intraocular Pressure among awake patients in supine position in Isoflurane and Propofol groups were 15.8 ...

Purpose: To report a case of spontaneous exposure of anterior chamber intraocular lens in a patie... more Purpose: To report a case of spontaneous exposure of anterior chamber intraocular lens in a patient with history of congenital cataract surgery ten years prior to presentation. Report of the case: A 27-year-old man presented with a two-year history of blurred vision, photophobia, mild ocular pain and redness in his left eye, with no history of prolonged eye rubbing, ocular surface disease or any evidence of trauma. On exam there was redness and swelling of the eyelids in the involved side; however, there was no evidence of any long standing ocular surface condition. Slit-lamp biomicroscopy disclosed an injected eye with haptic exposure of an angle-supported anterior chamber lens approximately 1 mm posterior to the limbus through the sclera. Anterior chamber was mildly inflamed and pupil was peaked towards the area of the exposed haptic. Ultrasound biomicroscopy revealed edematous and thickened sclera near the exposed tip. The dislocated lens was extracted and an iris-fixated anterio...