ahmad tajehmiri | Kermanshah University Of Medical Science (original) (raw)

Papers by ahmad tajehmiri

Jundishapur Journal of Microbiology

Background: The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has... more Background: The spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been undergoing variation. Most of the variants cause no concern for human health. Some others have had worse outcomes in terms of transmissibility, vaccination resistance, and, generally, the survival of patients infected with SARS-CoV-2. Objectives: This study investigated the mutation of interest in the receptor-binding domain (RBD) of SARS-CoV-2. Methods: Ribonucleic acid (RNA) was extracted from 40 swap samples. Next, the polymerase chain reaction (PCR) assay was carried out to detect the RBD. Investigation of SARS-COV-2 RBD was performed completely by phylogenetic and tree alignment. The multiple sequence alignment (MSA) of the biological sequence of RBD was created by BioEdit, Snap Gene, and MEGA software and was then compared to sequences of different variants of SARS-COV-2 in the GenBank (National Center for Biotechnology Information). The Influenza Surveillance and Response Sy...

مجله علمی دانشگاه علوم پزشکی کردستان, 2015

Scientific Journal of Animal Science, 2014

During recentdecades, the contamination of cereal grains with toxic metabolites of Fusariumspecie... more During recentdecades, the contamination of cereal grains with toxic metabolites of Fusariumspecies has been increasingly documented. Deoxynivalenol (DON) is one of themost common trichothecene toxins produced by F. graminearum. Wheat,rice, corn (maize), oats, barley and other grains used for human and animalconsumption are frequently contaminated with DON. DON affects animal and humanhealth causing vomiting, acute temporary nausea, diarrhea, abdominal pain,headache, dizziness, and fever. In this paper, we reviewed recent studies inDON contamination in cereals and cereal based products.

Journal of Polymer Research, Jul 7, 2022

Bioinorganic Chemistry and Applications, Oct 22, 2021

Background. Wound healing is a complex process of replacing devitalized cellular structures and t... more Background. Wound healing is a complex process of replacing devitalized cellular structures and tissues with healthy cells and tissue. Nanotechnology has been increasingly proposed as a novel platform to treat wounds and skin regeneration. e aim of this study was to evaluate the antibacterial, antioxidant, cytotoxic, and cutaneous wound healing activities of phytosynthesized Au NPs using Abelmoschus esculentus (okra) and synthesized Au NPs by using the citrate synthesis method. e Ok Au NPs were characterized using various techniques like UV-Vis absorption spectroscopy, FTIR, X-ray diffraction (XRD), and transmission electron microscopy (TEM). Cutaneous wounds were created on 30 rats and randomized into three groups: untreated and two groups treated with Ch Au NPs and Ok Au NPs. e treatment was carried out daily for 12 days. A peak characterized the Ok Au NPs at 538 nm in the UV-Vis spectrum. Based on the results of FTIR spectroscopy, various functional oxygenated groups such as hydroxyl, carboxyl, and nitrogenous groups were observed. XRD confirmed the crystalline nature of the nanoparticles. TEM images of Ok Au NPs showed a spherical shape and size range of 75 nm. DPPH test showed similar antioxidant potentials for Au NPs. e Au NPs showed cell viability in a dose-dependent manner, and this technique was found to be nontoxic. Agar well diffusion, which is the method to determine antibacterial characteristics of Au NPs, showed a significant beneficial effect against a variety of bacterial species. In addition, histopathological results showed that Au NPs could accelerate wound closure. erefore, Au NPs could be suitable for wound healing applications.

Journal of Drug Delivery Science and Technology, Mar 1, 2023

Journal of Drug Delivery Science and Technology

Journal of Polymer Research

Lack of association between rs1799983 polymorphism and Parkinson's disease in Iran

Copyright © 2014 Masoud Hassani Kolavani et al. This is an open access article distributed under ... more Copyright © 2014 Masoud Hassani Kolavani et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In recent years, the usage of plant materials as food supplement and as alternative medicine has increased. Medicinal herbs are a rich source of antimicrobial agents. In this investigation, antimicrobial effects of leaf methanol and ethanol extracts of Artemisia annua against Staphylococcus aureus PTCC 1431, Salmonella enterica PTCC 1231, Klebsiella pneumonia PTCC 1053, Shigella dysenteriae PTCC 1188 and Escherichia coli PTCC 1399 were studied, using well diffusion method. Methanol and ethanol extracts obtained from leaves of A. annua exhibited antimicrobial activity against test microorganisms. The methanol extract of A. annua showed high inhibition of the growth of S. aureus PTCC 1431, S. enterica PTCC 1231 with inhibitory...

Asian Pacific Journal of Cancer Prevention : APJCP, 2016

Background: The x-ray repair cross-complementing group 3 (XRCC3) encodes a protein involved in th... more Background: The x-ray repair cross-complementing group 3 (XRCC3) encodes a protein involved in the homologous recombination repair (HRR) pathway for double-strand DNA repair. Associations of the XRCC3 Thr241Met polymorphism with various cancers have been widely reported. However, published data on links between XRCC3 Thr241Met and gastrointestinal (GI) cancer risk are inconsistent. Objective and Methods: A meta-analysis was conducted to characterize the relationship between XRCC3 Thr241Met polymorphisms and GI cancer risk. Pooled odds ratios (ORs) and 95.0% confidence intervals were assessed using random- or fixed- effect models for 28.0 relevant articles with 30.0 studies containing 7,649.0 cases and 11,123.0 controls. Results: The results of the overall meta-analysis suggested a borderline association between the XRCC3 Thr241Met polymorphism and GI cancer susceptibility (T vs. C: OR=1.18, 9 % CI=1.0–1.4, POR=0.04; TT vs. CT+CC: OR=1.3, 95 % CI=1.0–1.6, POR=0.04). After removing st...

Catatonic schizophrenia is one of several subtypes of schizophrenia, a psychological disorder tha... more Catatonic schizophrenia is one of several subtypes of schizophrenia, a psychological disorder that usually emerges in late adolescence or early adulthood, however, it can appear at any time in life. Several studies have shown that Nitric oxide (NO) has several important roles in schizophrenia with type 2 Diabetes. Several studies have demonstrated that that eNOS might play a role in schizophrenia and type 2 Diabetes .We conducted study including a clinically well-defined group of 67 schizophrenia with type 2Diabetespatients and 60 healthy case to test the association between NOS3 G894T polymorphism and schizophrenia and type 2 Diabetes in Iranian population. So the NOS3 gene G894T polymorphism were carried out using ARMS-PCR method and then, the data were analyzed by SPSS software.The results of this study showed considerable association between Catatonic Schizophrenia with type 2 Diabetes disease and NOS3 gene G894T polymorphism in Iranian population.

Introduction: Some of the natural and synthetic compounds with antioxidant properties play an imp... more Introduction: Some of the natural and synthetic compounds with antioxidant properties play an important role to protect testis and epididymis against destructive factors.The purpose of this study was to investigate the protective effect of aqueous extract of Melissa officinalsin combination with Ziziphus juju be against the testis and epididymis lead poisoning in mice. Methods: A sum of 40 male mice with an average weight of 35-30 g and then randomly divided into four equal groups Compatible courses, Include: (1) Control group: saline recipient. (2) Sham group1: received lead acetate for 7 days and after 25 days of normal diet. (3) Sham group2: received formulations for 25 days with a dose of 200 mg/kg. (4) Intervention group: This received a solution of lead acetate in drinking water at a dose (ppm1000) for 7 days and 25 days post -dose formulation 200 mg/kg, the results of the statistical program SPSS software, one way ANOVA and T-test range test were used for statistical analysis...

Aflatoxins are large groups of mycotoxins that are produced by specific species of molds. Aflatox... more Aflatoxins are large groups of mycotoxins that are produced by specific species of molds. Aflatoxin B1 (AFB1) has been known as the most potent toxin among various aflatoxins. Aflatoxins are highly toxic, immunosuppressive, mutagenic, teratogenic, and carcinogenic compounds. The main target organ for their toxicity and carcinogenicity is the liver . Probiotics are microbial food supplements that beneficially affect the health of the host. Probiotic bacteria are used to balance the intestinal flora and to prevent several gastrointestinal disorders. In this review, recent developments in biocontrol of AFB1 by probiotic bacteria have been investigated.

The biological removing method is cheap and safe for the environment. The Cadmium is toxic and ha... more The biological removing method is cheap and safe for the environment. The Cadmium is toxic and harmful for the environment; therefore, the biological removing programs were developed for deletion of this metal from waste. Detection of persisting bacteria to toxic metals and using them for removing heavy metal from arouses environments and wastewaters is very important. In this study the ability of Halomonas elongate IBRC-M10433 bacterium was achieved from Urmia Salt Lake was tested to remove of Cadmium in wastewaters. For achievement optimised of different environmental factors such as Cadmium, Glucose and salt for removal of Cadmium from H. elongate IBRC-M10433, we used Taguchi method. Results from this study showed that H. elongate IBRC-M10433 persists to Cadmium metal. The largest Cadmium removal (85%) was seen in the culture that contains 50 ppm Cadmium, Glucose 10 g/L and NaCl 200 g/L.

Introduction: Diabetes mellitus is the most common endocrine disorder that impairs glucose homeos... more Introduction: Diabetes mellitus is the most common endocrine disorder that impairs glucose homeostasis resulting in severe diabetic complications including retinopathy, angiopathy, nephropathy, and neuropathy causing neurological disorders due to perturbation in utilization of glucose. Gundelia tournefortii L. is a medicinal plant, native to Asia, used as an occasional food source, and its extracts have been used for prevention and treatment of diabetes disease. Aim: The aim of this study was to effects of aqueous extract of gunnera (Gundelia tournefortii L) on the blood serum sugar levels and changes in the streptozotocin-induced diabetic pancreatic tissue of rat. Methods: A sum of 36 male Wistar rats were categorized into six study groups. In a 21 day study period, aqueous extract were given every day throughout the study period whereas. On day 21, fasting blood samples, body mass and pancreatic tissues were collected and processed for blood sugar estimation and the determined val...

Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to ... more Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH changes on the different formulation of CH with hydrophilic natural polymers over a period of 30 days. Various formulations were prepared by combining CH with gelatin, aloe vera and gum tragacanth. Root canals of 60 human teeth were instrumented and filled with a different formulation of CH and suspended in plastic tubes containing distilled water. Three formulas of polymer/CH were evaluated, and pure CH powder was used as a control. At specific time intervals, the calcium ions release and the pH changes of the medium in different formulations were analyzed. The main interactions between the studi...

Catatonic schizophrenia is one of several subtypes of schizophrenia, marked by symptoms such as r... more Catatonic schizophrenia is one of several subtypes of schizophrenia, marked by symptoms such as rigidity, excitement and stupor .Several studies have shown that Nitric oxide (NO) has several important roles in schizophrenia. Studies have demonstrated that the NO level of plasma, serum and postmortem brain from patients with Schizophrenia are increased and they have an abnormal NOS/NO pathway. NO is created by three nitric oxide synthase (NOS) isoenzymes, including endothelial NOS (eNOS), neuronal NOS (nNOS) and inducible NOS (iNOS).Evidence suggests that eNOS might play a role in this mysterious disease, as a result we studied eNOSG/T894 polymorphism in Iranian patient affected by

Mesenchymal stem cells (MSCs), as major stem cells for cell therapy, have been studied from diffe... more Mesenchymal stem cells (MSCs), as major stem cells for cell therapy, have been studied from different aspects in preclinical and clinical settings for more than a decade. These cells modulate the immune system (humoral and cellular immune responses) in vitro by producing soluble factors (anti-inflammatory molecules) and/or making cell-cell contacts. Hence, they could be used in regenerative medicine, tissue engineering and immune therapy. MSCs-based therapy have been recently used for treatment of cancer regarding the migratory potential of these cells towards tumor cells which makes them considerable candidates, also for cell therapy in both allogeneic and autologous settings. So, this review attempts to focus on the factors secreted by MSCs such as cytokines, their functional role in mounting and controlling immune responses mediated by different immune cell subpopulations and their significance in regenerative medicine in clinical trials. Although, further studies remain to be do...