Muller, S., Hoege, C., Pyrowolakis, G., and Jentsch, S. (2001) SUMO, ubiquitin's mysterious cousin. Nat Rev Mol Cell Biol2, 202–210. ArticlePubMedCAS Google Scholar
Bernier-Villamor, V., Sampson, D. A., Matunis, M. J., and Lima, C. D. (2002) Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1. Cell108, 345–356. ArticlePubMedCAS Google Scholar
Yunus, A. A., and Lima, C. D. (2006) Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway. Nat Struct Mol Biol13, 491–499. ArticlePubMedCAS Google Scholar
Cheng, C. H., Lo, Y. H., Liang, S. S., Ti, S. C., Lin, F. M., Yeh, C. H., Huang, H. Y., and Wang, T. F. (2006) SUMO modifications control assembly of synaptonemal complex and polycomplex in meiosis of Saccharomyces cerevisiae. Genes Dev20, 2067–2081. ArticlePubMedCAS Google Scholar
Hochstrasser, M. (2001) SP-RING for SUMO: new functions bloom for a ubiqui-tin-like protein. Cell107, 5–8. ArticlePubMedCAS Google Scholar
Johnson, E. S., and Gupta, A. A. (2001) An E3-like factor that promotes SUMO conjugation to the yeast septins. Cell106, 735–744. ArticlePubMedCAS Google Scholar
Kahyo, T., Nishida, T., and Yasuda, H. (2001) Involvement of PIAS1 in the sumoylation of tumor suppressor p53. Mol Cell8, 713–718. ArticlePubMedCAS Google Scholar
Potts, P. R., and Yu, H. (2005) Human MMS21/NSE2 is a SUMO ligase required for DNA repair. Mol Cell Biol25, 7021–7032. ArticlePubMedCAS Google Scholar
Schmidt, D., and Muller, S. (2003) PIAS/ SUMO: new partners in transcriptional regulation. Cell Mol Life Sci60, 2561–2574. ArticlePubMedCAS Google Scholar
Takahashi, Y., Toh-e, A., and Kikuchi, Y. (2001) A novel factor required for the SUMO1/Smt3 conjugation of yeast septins. Gene275, 223–231. ArticlePubMedCAS Google Scholar
Zhao, X., and Blobel, G. (2005) A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A102, 4777–4782. ArticlePubMedCAS Google Scholar
Pichler, A., Gast, A., Seeler, J. S., Dejean, A., and Melchior, F. (2002) The nucleop-orin RanBP2 has SUMO1 E3 ligase activity. Cell108, 109–120. ArticlePubMedCAS Google Scholar
Pichler, A., Knipscheer, P., Saitoh, H., Sixma, T. K., and Melchior, F. (2004) The RanBP2 SUMO E3 ligase is neither HECT- nor RING-type. Nat Struct Mol Biol11, 984–991. ArticlePubMedCAS Google Scholar
Reverter, D., and Lima, C. D. (2005) Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex. Nature435, 687–692. ArticlePubMedCAS Google Scholar
Mossessova, E., and Lima, C. D. (2000) Ulp1-SUMO crystal structure andgenetic analysis reveal conserved interactions and a regulatory element essential for cellgrowth in yeast. Mol Cell5, 865–876. ArticlePubMedCAS Google Scholar
Hoege, C., Pfander, B., Moldovan, G. L., Pyrowolakis, G., and Jentsch, S. (2002) RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature419, 135–141. ArticlePubMedCAS Google Scholar
Pfander, B., Moldovan, G. L., Sacher, M., Hoege, C., and Jentsch, S. (2005) SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase. Nature436, 428–433. PubMedCAS Google Scholar
Fersht, A. (2000) The pH dependence of enzyme catalysis. in Structure and Mechanism in Protein Science, W.H Freeman and Company, New York. Google Scholar