- Ahn S, Nelson CD, Garrison TR, Miller WE, Lefkowitz RJ (2003) Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference. Proc Natl Acad Sci USA 100:1740–1744
Article PubMed CAS Google Scholar
- Altankov G, Grinnell F (1993) Depletion of intracellular potassium disrupts coated pits and reversibly inhibits cell polarization during fibroblast spreading. J Cell Biol 120:1449–1459
Article PubMed CAS Google Scholar
- Bauer M, Pelkmans L (2006) A new paradigm for membrane-organizing and -shaping scaffolds. FEBS Lett 580:5559–5564
Article PubMed CAS Google Scholar
- Beck KA, Keen JH (1991) Interaction of phosphoinositide cycle intermediates with the plasma membrane-associated clathrin assembly protein AP-2. J Biol Chem 266:4442–4447
PubMed CAS Google Scholar
- Berdnik D, Torok T, Gonzalez-Gaitan M, Knoblich JA (2002) The endocytic protein alpha-adaptin is required for numb-mediated asymmetric cell division in Drosophila. Dev Cell 3:221–231
Article PubMed CAS Google Scholar
- Boehm M, Bonifacino JS (2001) Adaptins: the final recount. Mol Biol Cell 12:2907–2920
PubMed CAS Google Scholar
- Boll W, Rapoport I, Brunner C, Modis Y, Prehn S, Kirchhausen T (2002) The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppO sorting signals at distinct sites. Traffic 3: 590–600
Article PubMed CAS Google Scholar
- Bonifacino JS, Traub LM (2003) Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu Rev Biochem 72:395–447
Article PubMed CAS Google Scholar
- Bonifacino JS, Lippincott-Schwartz J (2003) Coat proteins: shaping membrane transport. Nat Rev Mol Cell Biol 4:409–414
Article PubMed CAS Google Scholar
- Chen YJ, Zhang P, Egelman EH, Hinshaw JE (2004) The stalk region of dynamin drives the constriction of dynamin tubes. Nat Struct Mol Biol 11:574–557
Article PubMed CAS Google Scholar
- Collins BM, McCoy AJ, Kent HM, Evans PR, Owen DJ (2002) Molecular architecture and functional model of the endocytic AP2 complex. Cell 109:523–535
Article PubMed CAS Google Scholar
- Conner SD, Schmid SL (2003) Regulated portals of entry into the cell. Nature 422:37–44
Article PubMed CAS Google Scholar
- Cremona O, Di Paolo G, Wenk MR, Luthi A, Kim WT, Takei K, Daniell L, Nemoto Y, Shears SB, Flavell RA, McCormick DA, De Camilli P (1999) Essential role of phosphoinositide metabolism in synaptic vesicle recycling. Cell 99:179–188
Article PubMed CAS Google Scholar
- Dell’Angelica EC (2001) Clathrin-binding proteins: got a motif? Join the network! Trends Cell Biol 11: 315–318
Article PubMed Google Scholar
- Derkach VA, Oh MC, Guire ES, Soderling TR (2007) Regulatory mechanisms of AMPA receptors in synaptic plasticity. Nat Rev Neurosci 8:101–113
Article PubMed CAS Google Scholar
- Di Paolo G, De Camilli P (2006) Phosphoinositides in cell regulation and membrane dynamics. Nature 443:651–657
Article PubMed CAS Google Scholar
- Diril MK, Wienisch M, Jung N, Klingauf J, Haucke V (2006) Stonin 2 is an AP-2-dependent endocytic sorting adaptor for synaptotagmin internalization and recycling. Dev Cell 10:233–244
Article PubMed CAS Google Scholar
- Dudu V, Pantazis P, Gonzalez-Gaitan M (2004) Membrane traffic during embryonic development: epithelial formation, cell fate decisions and differentiation. Curr Opin Cell Biol 16: 407–414
Article PubMed CAS Google Scholar
- Edeling MA, Mishra SK, Keyel PA, Steinhauser AL, Collins BM, Roth R, Heuser JE, Owen DJ, Traub LM (2006a) Molecular switches involving the AP-2 beta2 appendage regulate endocytic cargo selection and clathrin coat assembly. Dev Cell 10:329–342
Article PubMed CAS Google Scholar
- Edeling MA, Smith C, Owen D (2006b) Life of a clathrin coat: insights from clathrin and AP structures. Nat Rev Mol Cell Biol 7:32–44
Article PubMed CAS Google Scholar
- Fergestad T, Broadie K (2001) Interaction of stoned and synaptotagmin in synaptic vesicle endocytosis. J Neurosci 21:1218–1227
PubMed CAS Google Scholar
- Gaidarov I, Keen JH (1999) Phosphoinositide-AP-2 interactions required for targeting to plasma membrane clathrin-coated pits. J Cell Biol 146:755–764
Article PubMed CAS Google Scholar
- Gaidarov I, Smith ME, Domin J, Keen JH (2001) The class II phosphoinositide 3-kinase C2alpha is activated by clathrin and regulates clathrin-mediated membrane trafficking. Mol Cell 7:443–449
Article PubMed CAS Google Scholar
- Galli T, Haucke V (2004) Cycling of synaptic vesicles: how far? How fast! Sci STKE 2004: re19
Article Google Scholar
- Glebov OO, Bright NA, Nichols BJ (2006) Flotillin-1 defines a clathrin-independent endocytic pathway in mammalian cells. Nat Cell Biol 8:46–54
Article PubMed CAS Google Scholar
- Gonzalez-Gaitan M, Jackle H (1997) Role of Drosophila alpha-adaptin in presynaptic vesicle recycling. Cell 88:767–776
Article PubMed CAS Google Scholar
- Gupta-Rossi N, Six E, LeBail O, Logeat F, Chastagner P, Olry A, Israel A, Brou C (2004) Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor. J Cell Biol 166:73–83
Article PubMed CAS Google Scholar
- Hansen SH, Sandvig K, van Deurs B (1993) Clathrin and HA2 adaptors: effects of potassium depletion, hypertonic medium, and cytosol acidification. J Cell Biol 121:61–72
Article PubMed CAS Google Scholar
- Harris TW, Hartwieg E, Horvitz HR, Jorgensen EM (2000) Mutations in synaptojanin disrupt synaptic vesicle recycling. J Cell Biol 150:589–600
Article PubMed CAS Google Scholar
- Haucke V (2005) Phosphoinositide regulation of clathrin-mediated endocytosis. Biochem Soc Trans 33:1285–1289
Article PubMed CAS Google Scholar
- Haucke V (2006) Cargo takes control of endocytosis. Cell 127:35–37
Article PubMed CAS Google Scholar
- Henley JR, Krueger EW, Oswald BJ, McNiven MA (1998) Dynamin-mediated internalization of caveolae. J Cell Biol 141:85–99
Article PubMed CAS Google Scholar
- Heuser J (1989) Effects of cytoplasmic acidification on clathrin lattice morphology. J Cell Biol 108:401–411
Article PubMed CAS Google Scholar
- Heuser JE, Anderson RG (1989) Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation. J Cell Biol 108:389–400
Article PubMed CAS Google Scholar
- Heuser JE, Keen J (1988) Deep-etch visualization of proteins involved in clathrin assembly. J Cell Biol 107:877–886
Article PubMed CAS Google Scholar
- Hinrichsen L, Harborth J, Andrees L, Weber K, Ungewickell EJ (2003) Effect of clathrin heavy chain- and alpha-adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in HeLa cells. J Biol Chem 278:45160–45170
Article PubMed CAS Google Scholar
- Hinrichsen L, Meyerholz A, Groos S, Ungewickell EJ (2006) Bending a membrane: how clathrin affects budding. Proc Natl Acad Sci USA 103:8715–8720
Article PubMed CAS Google Scholar
- Honing S, Ricotta D, Krauss M, Spate K, Spolaore B, Motley A, Robinson M, Robinson C, Haucke V, Owen DJ (2005) Phosphatidylinositol-(4,5)-bisphosphate regulates sorting signal recognition by the clathrin-associated adaptor complex AP2. Mol Cell 18:519–531
Article PubMed CAS Google Scholar
- Huang F, Khvorova A, Marshall W, Sorkin A (2004) Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference. J Biol Chem 279:16657–16661
Article PubMed CAS Google Scholar
- Jha A, Agostinelli NR, Mishra SK, Keyel PA, Hawryluk MJ, Traub LM (2004) A novel AP-2 adaptor interaction motif initially identified in the long-splice isoform of synaptojanin 1, SJ170. J Biol Chem 279:2281–2290
Article PubMed CAS Google Scholar
- Jones C, Garuti R, Michaely P, Li WP, Maeda N, Cohen JC, Herz J, Hobbs HH (2007) Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia. J Clin Invest 117:165–1674
Article PubMed CAS Google Scholar
- Jost M, Simpson F, Kavran JM, Lemmon MA, Schmid SL (1998) Phosphatidylinositol-4,5-bisphosphate is required for endocytic coated vesicle formation. Curr Biol 8:1399–102
Article PubMed CAS Google Scholar
- Kastning K, Kukhtina V, Kittler JT, Chen G, Pechstein A, Enders S, Lee SH, Sheng M, Yan Z, Haucke V (2007) Molecular determinants for the interaction between AMPA receptors and the clathrin adaptor complex AP-2. Proc Natl Acad Sci USA 104:2991–2996
Article PubMed CAS Google Scholar
- Kirchhausen T (1999) Adaptors for clathrin-mediated traffic. Annu Rev Cell Dev Biol 15: 705–732
Article PubMed CAS Google Scholar
- Kirchhausen T (2000) Clathrin. Annu Rev Biochem 69:699–727
Article PubMed CAS Google Scholar
- Krauss M, Haucke V (2007) Phosphoinositides: Regulators of membrane traffic and protein function. FEBS Lett 581: 2015–2011
Article CAS Google Scholar
- Krauss M, Kinuta M, Wenk MR, De Camilli P, Takei K, Haucke V (2003) ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Igamma. J Cell Biol 162:113–124
Article PubMed CAS Google Scholar
- Lakadamyali M, Rust MJ, Zhuang X (2006) Ligands for clathrin-mediated endocytosis are differentially sorted into distinct populations of early endosomes. Cell 124:997–1009
Article PubMed CAS Google Scholar
- Larkin JM, Brown MS, Goldstein JL, Anderson RG (1983) Depletion of intracellular potassium arrests coated pit formation and receptor-mediated endocytosis in fibroblasts. Cell 33: 273–285
Article PubMed CAS Google Scholar
- Lee SH, Simonetta A, Sheng M (2004) Subunit rules governing the sorting of internalized AMPA receptors in hippocampal neurons. Neuron 43:221–236
Article PubMed CAS Google Scholar
- Lefkowitz RJ, Shenoy SK (2005) Transduction of receptor signals by beta-arrestins. Science 308:512–517
Article PubMed CAS Google Scholar
- Lewin DA, Mellman I (1998) Sorting out adaptors. Biochim Biophys Acta 1401:129–145
Article PubMed CAS Google Scholar
- Macia E, Ehrlich M, Massol R, Boucrot E, Brunner C, Kirchhausen T (2006) Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell 10:839–850
Article PubMed CAS Google Scholar
- Maldonado-Baez L, Wendland B (2006) Endocytic adaptors: recruiters, coordinators and regulators. Trends Cell Biol 16:505–513
Article PubMed CAS Google Scholar
- Martina JA, Bonangelino CJ, Aguilar RC, Bonifacino JS (2001) Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery. J Cell Biol 153:1111–1120
Article PubMed CAS Google Scholar
- Maycox PR, Link E, Reetz A, Morris SA, Jahn R (1992) Clathrin-coated vesicles in nervous tissue are involved primarily in synaptic vesicle recycling. J Cell Biol 118:1379–1388
Article PubMed CAS Google Scholar
- McNiven MA (1998) Dynamin: a molecular motor with pinchase action. Cell 94:151–14
Article PubMed CAS Google Scholar
- Mitsunari T, Nakatsu F, Shioda N, Love PE, Grinberg A, Bonifacino JS, Ohno H (2005) Clathrin adaptor AP-2 is essential for early embryonal development. Mol Cell Biol 25:9318–9323
Article PubMed CAS Google Scholar
- Morrow IC, Parton RG (2005) Flotillins and the PHB domain protein family: rafts, worms and anaesthetics. Traffic 6:725–740
Article PubMed CAS Google Scholar
- Motley A, Bright NA, Seaman MN, Robinson MS (2003) Clathrin-mediated endocytosis in AP-2-depleted cells. J Cell Biol 162:909–918
Article PubMed CAS Google Scholar
- Motley AM, Berg N, Taylor MJ, Sahlender DA, Hirst J, Owen DJ, Robinson MS (2006) Functional analysis of AP-2 alpha and mu2 subunits. Mol Biol Cell 17:5298–5308
Article PubMed CAS Google Scholar
- Mukherjee S, Ghosh RN, Maxfield FR (1997) Endocytosis. Physiol Rev 77:759–803
PubMed CAS Google Scholar
- Nesterov A, Carter RE, Sorkina T, Gill GN, Sorkin A (1999) Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis. EMBO J 18:2489–2499
Article PubMed CAS Google Scholar
- Newmyer SL, Christensen A, Sever S (2003) Auxilin-dynamin interactions link the uncoating ATPase chaperone machinery with vesicle formation. Dev Cell 4:929–940
Article PubMed CAS Google Scholar
- Ochoa GC, Slepnev VI, Neff L, Ringstad N, Takei K, Daniell L, Kim W, Cao H, McNiven M, Baron R, De Camilli P (2000) A functional link between dynamin and the actin cytoskeleton at podosomes. J Cell Biol 150:377–389
Article PubMed CAS Google Scholar
- Ohno H, Stewart J, Fournier MC, Bosshart H, Rhee I, Miyatake S, Saito T, Gallusser A, Kirchhausen T, Bonifacino JS (1995) Interaction of tyrosine-based sorting signals with clathrin-associated proteins. Science 269:1872–1875
Article PubMed CAS Google Scholar
- Owen DJ, Evans PR (1998) A structural explanation for the recognition of tyrosine-based endocytotic signals. Science 282:1327–1332
Article PubMed CAS Google Scholar
- Owen DJ, Luzio JP (2000) Structural insights into clathrin-mediated endocytosis. Curr Opin Cell Biol 12:467–474
Article PubMed CAS Google Scholar
- Owen DJ, Vallis Y, Noble ME, Hunter JB, Dafforn TR, Evans PR, McMahon HT (1999) A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain. Cell 97:805–815
Article PubMed CAS Google Scholar
- Owen DJ, Setiadi H, Evans PR, McEver RP, Green SA (2001) A third specificity-determining site in mu 2 adaptin for sequences upstream of Yxx phi sorting motifs. Traffic 2:105–110
Article PubMed CAS Google Scholar
- Perera RM, Zoncu R, Lucast L, De Camilli P, Toomre D (2006) Two synaptojanin 1 isoforms are recruited to clathrin-coated pits at different stages. Proc Natl Acad Sci USA 103: 19332–19337
Article PubMed CAS Google Scholar
- Praefcke GJ, Ford MG, Schmid EM, Olesen LE, Gallop JL, Peak-Chew SY, Vallis Y, Babu MM, Mills IG, McMahon HT (2004) Evolving nature of the AP2 alpha-appendage hub during clathrin-coated vesicle endocytosis. EMBO J 23:4371–4383
Article PubMed CAS Google Scholar
- Puthenveedu MA, von Zastrow M (2006) Cargo regulates clathrin-coated pit dynamics. Cell 127: 113–124
Article PubMed CAS Google Scholar
- Ricotta D, Conner SD, Schmid SL, von Figura K, Honing S (2002) Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals. J Cell Biol 156:791–795
Article PubMed CAS Google Scholar
- Ritter B, Philie J, Girard M, Tung EC, Blondeau F, McPherson PS (2003) Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif. EMBO Rep 4: 1089–1095
Article PubMed CAS Google Scholar
- Robinson MS, Bonifacino JS (2001) Adaptor-related proteins. Curr Opin Cell Biol 13:444–453
Article PubMed CAS Google Scholar
- Rohde G, Wenzel D, Haucke V (2002) A phosphatidylinositol (4,5)-bisphosphate binding site within mu2-adaptin regulates clathrin-mediated endocytosis. J Cell Biol 158:209–214
Article PubMed CAS Google Scholar
- Roux A, Uyhazi K, Frost A, De Camilli P (2006) GTP-dependent twisting of dynamin implicates constriction and tension in membrane fission. Nature 441:528–531
Article PubMed CAS Google Scholar
- Sandvig K, Olsnes S, Petersen OW, van Deurs B (1987) Acidification of the cytosol inhibits endocytosis from coated pits. J Cell Biol 105:679–689
Article PubMed CAS Google Scholar
- Schweizer FE, Ryan TA (2006) The synaptic vesicle: cycle of exocytosis and endocytosis. Curr Opin Neurobiol 16:298–304
Article PubMed CAS Google Scholar
- Sorkin A, Carpenter G (1993) Interaction of activated EGF receptors with coated pit adaptins. Science 261:612–615
Article PubMed CAS Google Scholar
- Stang E, Blystad FD, Kazazic M, Bertelsen V, Brodahl T, Raiborg C, Stenmark H, Madshus IH (2004) Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits. Mol Biol Cell 15:3591–3604
Article PubMed CAS Google Scholar
- Stimson DT, Estes PS, Rao S, Krishnan KS, Kelly LE, Ramaswami M (2001) Drosophila stoned proteins regulate the rate and fidelity of synaptic vesicle internalization. J Neurosci 21: 3034–3044
PubMed CAS Google Scholar
- Takamori S, Holt M, Stenius K, Lemke EA, Gronborg M, Riedel D, Urlaub H, Schenck S, Brugger B, Ringler P, Muller SA, Rammner B, Grater F, Hub JS, De Groot BL, Mieskes G, Moriyama Y, Klingauf J, Grubmuller H, Heuser J, Wieland F, Jahn R (2006) Molecular anatomy of a trafficking organelle. Cell 127:831–846
Article PubMed CAS Google Scholar
- Takei K, Haucke V (2001) Clathrin-mediated endocytosis: membrane factors pull the trigger. Trends Cell Biol 11:385–391
Article PubMed CAS Google Scholar
- Thompson HM, Cao H, Chen J, Euteneuer U, McNiven MA (2004) Dynamin 2 binds gamma-tubulin and participates in centrosome cohesion. Nat Cell Biol 6:335–342
Article PubMed CAS Google Scholar
- Traub LM (2003) Sorting it out: AP-2 and alternate clathrin adaptors in endocytic cargo selection. J Cell Biol 163:203–208
Article PubMed CAS Google Scholar
- Traub LM (2005) Common principles in clathrin-mediated sorting at the Golgi and the plasma membrane. Biochim Biophys Acta 1744:415–437
Article PubMed CAS Google Scholar
- Varnai P, Thyagarajan B, Rohacs T, Balla T (2006) Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact living cells. J Cell Biol 175:377–382
Article PubMed CAS Google Scholar
- Walther K, Diril MK, Jung N, Haucke V (2004) Functional dissection of the interactions of stonin 2 with the adaptor complex AP-2 and synaptotagmin. Proc Natl Acad Sci USA 101:964–969
Article PubMed CAS Google Scholar
- Wang LH, Rothberg KG, Anderson RG (1993) Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation. J Cell Biol 123:1107–1117
Article PubMed CAS Google Scholar
- Wang H, Traub LM, Weixel KM, Hawryluk MJ, Shah N, Edinger RS, Perry CJ, Kester L, Butterworth MB, Peters KW, Kleyman TR, Frizzell RA, Johnson JP (2006) Clathrin-mediated endocytosis of the epithelial sodium channel. Role of epsin. J Biol Chem 281:14129–14135
Article PubMed CAS Google Scholar