Molecular mapping of obesity genes (original) (raw)

References

• Abbs, S., Roberts, R.G., Mathew, C.G., Bentley, D.R., and Bobrow, M.: Accurate assessment of intragenic recombination frequency within the Duchenne muscular dystrophy gene. Genomics 7: 602–606, 1990.
  Article CAS PubMed Google Scholar
• Altman, P.L.: Inbred and Genetically Defined Strains of Laboratory Animals: Part I, Mouse and Rat, 16–20, Federation of American Societies for Experimental Biology, Bethesda MD, 1979.
  Google Scholar
• Arase, K., Shargill, N.S., and Bray, G.A.: Effects of corticotropin releasing factor on genetically obese (fatty) rats. Physiol Behav 45, 565–570, 1989.
  Article CAS PubMed Google Scholar
• Bahary, N., Leibel, R.L., Joseph L., and Friedman, J.M.: Molecular mapping of the mouse db mutation. Proc Natl Acad Sci USA 87: 8642–8646, 1990.
  Article CAS PubMed Google Scholar
• Balling, R., Deutsch, U., and Gruss, P: Undulated, a mutation affecting the development of the mouse skeleton, has a point mutation in the paired box of Pax-1. Cell 55: 531–535, 1988.
  Article CAS PubMed Google Scholar
• Batt, R.A.: Decreased food intake in response to cholecystokinin (pancreozymin) in wild-type and obese mice (genotype oblob). Int J Obes 7: 25–29, 1983.
  CAS PubMed Google Scholar
• Begin-Heick, NL: Absence of the inhibitory effect of guanine nucleotides on adenylate cyclase activity in white adipocyte membranes of the oblob mouse: Effect of the ob gene. J Biol Chem 260: 6187–6193, 1985.
  CAS PubMed Google Scholar
• Bielschowsky, M., and Bielschowsky, F.: A new strain of mice with hereditary obesity. Proc Univ Otago M School 31: 29, 1953.
  Google Scholar
• Bjorkland, A., Hokfelt, T., and Swanson, L.W.: Integrated systems of the CNS, Part I. Hypothalamus, hippocampus, amygdala, retina. In Handbook of Chemical Neuroanatomy. Elsevier Press, New York, 1987.
  Google Scholar
• Bray, G.A.: An approach to control of food intake in humans. Med Clin N Amer 73: 29–45, 1989a.
  CAS PubMed Google Scholar
• Bray, G.A.: Genetic and hypothalamic mechanisms for obesity—finding the needle in the haystack. Am J Clin Nutr 50: 891–902, 1989b.
  CAS PubMed Google Scholar
• Bray, G.A., Shimomura, Y., Ohtake, M., and Walker, P.: Salivary gland weight and nerve growth factor in the genetically obese (oblob) mouse. Endocrinology 110: 47–50, 1982.
  Article CAS PubMed Google Scholar
• Bray, G.A., York, D.A., and Fisler, J.S.: Experimental obesity: a homeostatic failure due to defective nutrient stimulation of the sympathetic nervous system. Vitamins and Hormones 45: 1–125, 1989.
  Article CAS PubMed Google Scholar
• Brown, M.R., and Fisher, L.A.: Corticotropin-releasing factor: Effects on the autonomic nervous system and visceral systems. Federation Proc 44: 243–248, 1985.
  CAS Google Scholar
• Brown, M.R., Fisher, L.A., Spiess, J., Rivier, C., Rivier, J., and Vale, W.: Corticotropin-releasing factor: Actions on the sympathetic nervous system and metabolism. Endocrinology 111: 928–931, 1982.
  Article CAS PubMed Google Scholar
• Burke, D.T., Rossi, J.M., Leung, J., Koos, D.S., and Tilghman, S.M.: A mouse genomic library of yeast artificial chromosome clones. Mammalian Genome 1: 65, 1991.
  Article CAS PubMed Google Scholar
• Camper, S.A., Saunders, T.L., Katz, R.W., and Reeves, R.H.: The Pit-1 transcription factor gene is a candidate for the murine snell dwarf mutation. Genomics 8: 586–590, 1990.
  Article CAS PubMed Google Scholar
• Cebra-Thomas, J.A., Decker, C.L., Snyder, L.C., Pilder, S.H., and Silver, L.M.: Allele- and haploid-specific product generated by alternative splicing from a mouse t complex responder locus candidate. Nature 349: 239, 1991.
  Article CAS PubMed Google Scholar
• Chabot, B., Stephenson, D.A., Chapman, V.M., Besmer, P., and Bernstein, A.: The protooncogene c-kit encoding a trasmembrane tyrosine kinase receptor maps to the mouse W locus. Nature 335: 88–89, 1988.
  Article CAS PubMed Google Scholar
• Coleman, D.L.: Effects of parabiosis of obese with diabetes and normal mice. Diabetologid 9: 294–298, 1973.
  Article CAS Google Scholar
• Coleman, D.L.: Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 14: 141–148, 1978.
  Article CAS PubMed Google Scholar
• Coleman, D.L.: Increased metablic efficiency in obese mutant mice. Intl J Obesity 9: 69–73, 1985.
  Google Scholar
• Coleman, D.L., and Eicher, E.M.: Fat (fat) and tubby (tub), two autosomal recessive mutations causing obesity syndromes in the mouse. J Heredity 81: 424–427, 1990.
  CAS Google Scholar
• Coleman, D.L., and Hummel, K.P.: Hyperinsulinemia in preweaning diabetes (db) mice. Diabetologia 10: 607–610, 1974.
  Article CAS PubMed Google Scholar
• Coleman, D.L., and Hummel, K.P.: Influence of genetic background on the expression of mutations at the diabetes locus in the mouse. II. Studies on background modifiers. Isr J Med 11: 708–718, 1975.
  CAS Google Scholar
• Copeland, N.G., Gilbert, D.J., Cho, B.C., Donovan, P.J., Jenkins, N.A., Cosman, D., Anderson, D., Lyman, S.D., and Williams, D.E.: Mast cell growth factor maps near the Steel locus on mouse Chromosome 10 and is deleted in a number of Steel alleles. Cell 63: 175–183, 1990.
  Article CAS PubMed Google Scholar
• D'Urso, M., Zucchi, I., Ciccodicola, A., Palmieri, G., Abidi, F.E., and Schlessinger, D.: Human glucose-6-phosphate dehydrogenase gene carried on a yeast artificial chromosome encodes active enzyme in monkey cells. Genomics 7: 531–534, 1990.
  Article PubMed Google Scholar
• Dickie, M.M., and Lane, P.W.: Mapping of the ob locus. Mouse News Lett 17: 52, 1957.
  Google Scholar
• Drumm, M.L., Smith, C.L., Dean, M., Cole, J.L., Iannuzzi, M.C., and Collins, F.S.: Physical mapping of the cystic fibrosis region by pulsed-field gel electrophoresis. Genomics 2: 346–354, 1988.
  Article CAS PubMed Google Scholar
• Elvin, P., Slynn, G., Black, D., Graham, A., Butler, R., Anand, R., and Markham, A.F.: Isolation of cDNA clone using yeast artificial chromosome probes. Nucl Acids Res 18: 3913–3917, 1990.
  Article CAS PubMed Google Scholar
• Fisher, E.M.C., Cavanna, J.S., and Brown, S.D.M.: Microdissection and microcloning of the mouse X Chromosome. Proc Natl Acad Sci USA 82: 5846–5849, 1985.
  Article CAS PubMed Google Scholar
• Flatt, J.P.: Dietary fat, carbohydrate balance, and weight maintenance: Effects of exercise. Am J Clin Nutr 45: 296–306, 1987.
  CAS PubMed Google Scholar
• Fletcher, C., Norman, D.J., and Heintz, N.: Genetic mapping of meander tail, a mouse mutation affecting cerebellar development. Genomics, in press, 1991.
• Foch, T.T., and McClearn, G.E.: Genetics, body weight and obesity. In A.J. Stunkard (ed.), Obesity, 48–71. Saunders, Philadelphia, 1980.
  Google Scholar
• Friedman, J.M., Leibel, R.L., Bahary, N. and Segal, D.A.: Molecular mapping of the mouse ob mutation. Submitted, 1991.
• Frohman, L.A., and Bernardis, L.L.: Effect of hypothalamic stimulation on plasma glucose, insulin, and glucagon levels. Am J Physiol 221: 1596–1603, 1971.
  CAS PubMed Google Scholar
• Garthwaite, T.L., Martinson, D.R., Tseng, L.F., Hagen, T.C., and Menahan, L.A.: A longitudinal hormonal profile of the genetically obese mouse. Endocrinology 107: 671–676, 1980.
  Article CAS PubMed Google Scholar
• Glaser, T., Rose, E., Morse, H., Housman, D., and Jones, C.: A panel of irradiation-reduced hybrids selectively retaining human Chromosome 11p13: Their structure and use to purify the WAGR gene complex. Genomics 6: 48–64, 1990.
  Article CAS PubMed Google Scholar
• Green, E.D., and Olson, M.V.: Chromosomal region of the cystic fibrosis gene in yeast artificial chromosomes: A model for human genome mapping. Science 250: 94–98, 1990.
  Article CAS PubMed Google Scholar
• Harris, R.B.S.: Role of set-point theory in regulation of body weight. FASEB J 4: 3310–3318, 1990.
  CAS PubMed Google Scholar
• Harris, R.B.S., Hervey, E., Hervey, G.R., and Tobin, G.: Body fat content in Zucker rats in parabiosis. J Physiol 312: 52, 1981.
  Google Scholar
• Herberg, L., and Coleman, D.L.: Laboratory animals exhibiting obesity and diabetes syndromes. Metabolism 26: 59, 1977.
  Article CAS PubMed Google Scholar
• Herrmann, B.G.: Labeit, S., Poustka, A., King, T.R., and Lehrach, H.: Cloning of the T gene required in mesoderm formation in the mouse. Nature 343: 617–622, 1990.
  Article CAS PubMed Google Scholar
• Hervey, G.R.: The effects of lesions in the hypothalamus in parabiotic rats. J Physiol 145: 336, 1959.
  CAS PubMed Google Scholar
• Hoebel, B.G.: Neurotransmitters in the control of feeding and its rewards: Manoanines, apiates and brain-gut peptides. In Eating and Its Disorders, 15–38, Raven Press, New York, 1984.
  Google Scholar
• Hummel, K.P., Coleman, D.L., and Lane, P.W.: The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL/KsJ and C57BL/6J strains. Biochem Genet 7: 1–3, 1972.
  Article CAS PubMed Google Scholar
• Jeanrenaud, B.: An hypothesis on the aetiology of obesity: Dysfunction of the central nervous system as a primary cause. Diabetologia 28: 502–513, 1985.
  Article CAS PubMed Google Scholar
• Johnson, P.R., Stern, J.S., Greenwood, M.R.C., Zucker, L.M., and Hirsch, J.: Effect of early nutrition on adipose cellularity and pancreatic insulin release in the Zucker rat. J Nutr 103: 738–743, 1973.
  CAS PubMed Google Scholar
• Keesey, R.E.: Physiological regulation of body weight and the issue of obesity. Med Clinics N Amer 73: 15–27, 1989.
  CAS Google Scholar
• Keesey, R.E., and Pawley, T.L.: The regulation of body weight. Ann Rev Psychol 37: 109–133, 1986.
  Article CAS Google Scholar
• Knowler, W.C., Pettitt, D.J., Bennett P.H., and Williams, R.C.: Diabetes mellitus in the Pima Indians: Genetic and evolutionary considerations. Am J Phys Anthr 82: 107–114, 1983.
  Article Google Scholar
• Lander, E.S., and Botstein, D.: Mapping Mendelian factors underlying quantitative traits using RFLP linkage maps. Genetics 121: 185–199, 1989.
  CAS PubMed Google Scholar
• Lane, P.W.: Mapping of the db locus. Mouse News Lett 38: 24, 1968.
  Google Scholar
• Larin, Z., Monaco, A.P., and Lehrach, H.: Yeast artificial chromosome libraries containing large inserts from mouse and human DNA. Proc Natl Acad Sci USA, in press, 1991.
• Leibel, R.L., Bahary, N. and Friedman, J.M.: Genetic variation and nutrition in obesity: Approaches to the molecular genetics of obesity. In A.P. simopoulos and B. Childs (eds.); Genetic Variation and Nutrition, pp. 90–101, Kanger, Basel, 1990a.
  Google Scholar
• Leibel, R.L.: Is obesity due to a heritable difference in “set point” for adiposity? West J Med 153: 429–431, 1990b.
  CAS PubMed Google Scholar
• Leibel, R.L., Edens, N.K., and Fried, S.K.: Physiologic basis for the control of body fat distribution in humans. Ann Rev Nutr 9: 417–443, 1989.
  Article CAS Google Scholar
• Leibel, R.L., and Hirsch, J.: Diminished energy requirements in reduced-obese patients. Metabolism 33: 164–170, 1984.
  Article CAS PubMed Google Scholar
• Leibowitz, S.F.: Brain monoamines and peptides: Roles in the control of eating behavior. Fed Proc 45: 1396–1403, 1986.
  CAS PubMed Google Scholar
• Leiter, E.H.: The influence of genetic background on expression of mutations at the diabetes locus in the mouse. IV. Male lethal syndrome in CBA/Lt mice. Diabetes 30: 1035–1044, 1981a.
  Article CAS PubMed Google Scholar
• Leiter, E.H., Coleman, D.L., and Hummel, K.P.: The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. III. Effect of H-2 haplotype and sex. Diabetes 30: 1029–1034, 1981b.
  Article CAS PubMed Google Scholar
• Lyons, M.J., Faust, I.M., Hemmes, R.B., Buskirk, D.R., Hirsch, J., and Zabriskie, J.B.: A virally-induced obesity syndrome in mice. Science 216: 82–85, 1982.
  Article CAS PubMed Google Scholar
• Mansour, S.L., Thomas, K.R., and Capecchi, M.R.: Disruption of the protooncogene Int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to non-selectable genes. Nature 336: 348–352, 1988.
  Article CAS PubMed Google Scholar
• Marshall, N.B., Barrnett, R.S., and Mayer, J.: Hypothalamic lesions in goldthioglucose injected mice. PSEBM 90: 240–244, 1955.
  CAS Google Scholar
• Mayer, J., French, R.G., Zighera, C.F., and Barrnett, R.J.: Hypothalamic obesity in the mouse production, description and metabolic characteristics. Am J Physiol 182: 75–82, 1955.
  CAS PubMed Google Scholar
• Monaco, A.P., Neve, R.L., Colletti-Feener, C., Bertelson, C.J., Kurnit, D.M., and Kunkel, L.M.: Isolation of candidate cDNAs for portions of the Duchenne muscular dystrophy gene. Nature 323: 646–650, 1985.
  Article Google Scholar
• Morley, J.: Neuropeptide regulation of appetite and weight. Endocrine Reviews 8: 256–286, 1987.
  Article CAS PubMed Google Scholar
• Mrosovsky, N., and Powley, T.L.: Set points for body weight and fat. Behav Biol 20: 205–223, 1977.
  Article CAS PubMed Google Scholar
• Nadeau, J.H.: Linkage and synteny homologies between mouse and man. Trends Genet 5: 82–86, 1990.
  Article Google Scholar
• Paterson, A.H., Lander, E.S., Hewitt, J.D., Peterson, S., Lincoln, S.E., and Tanksley, S.D.: Resolution of quantitative traits into Mendelian factors by using a complete linkage map of restriction fragment length polymorphisms. Nature 335: 721, 1988.
  Article CAS PubMed Google Scholar
• Pavan, W.J., Hieter, P., and Reeves, R.H.: Generation of deletion derivatives by targeted transformation of human-derived yeast artificial chromosomes. Proc Natl Acad Sci USA 87: 1300–1304, 1990.
  Article CAS PubMed Google Scholar
• Prochazka, M., Leiter, E.H., and Serreze, D.V.: Three recessive loci required for insulin-dependent diabetes in nonobese diabetic mice. Science 237: 286–289, 1987.
  Article CAS PubMed Google Scholar
• Ravelli, G.P., Stein, Z., and Susser, M.W.: Obesity in young men after famine exposure in utero and early infancy. N Engl J Med 295: 349–353, 1976.
  Article CAS PubMed Google Scholar
• Ravussin, E., Abbott, W., Zawakzki, J.K., Young, A., Knowler, W.C., Jacobowitz, R., and Moll, P.P.: Familial dependence of the resting metabolic rate. N Engl J Med 315: 96–100, 1986.
  PubMed Google Scholar
• Ravussin, E., Lillioja, S., Knowler, W.C., Dr., P.H., Christin, L., Freymond, D., Abbot, W.G.H., Boyce, V., Howard, B., and Bogardus, C.: Reduced rate of energy expenditure as a risk factor for body-weight gain. N Eng J Med 318: 467–472, 1988.
  Article CAS Google Scholar
• Readhead, C., Popko, B., Takahashi, N., David Shine, H., Saavedra, P.A., Sidman, R.L., and Hood, L.: Expression of a myelin basic protein gene in transgenic shiverer mice: Correction of the dysmyelinating phenotype. Cell 48: 703–712, 1987.
  Article CAS PubMed Google Scholar
• Reeders, S.T., Keith, T., Green, P., Germino, G.G., Barton, N.J., Lehmann, O.J., Brown, V.A., Phipps, P., Morgan, J., Bear, J.C., and Parfrey, P.: Regional localization of the autosomal dominant polycyctic kidney disease locus. Genomics 3: 150–155, 1988.
  Article CAS PubMed Google Scholar
• Reeves, R.H., Crowley, M.R., O'Hara, B.F., and Gearhart, J.D.: Sex, strain, and species differences affect recombination across an evolutionarily conserved segment of mouse Chromosome 16. Genomics 8: 141–148, 1990.
  Article CAS PubMed Google Scholar
• Robert, B., Barton, P., Minty, A., Daubas, P., Weydert, A., Bonhomme, F., Catalan, J., Chazottes, D., Guénet, J.-L., and Buckingham, M.: Investigation of genetic linkage between myosin and actin genes using an interspecific mouse backcross. Nature 314: 181–183, 1985.
  Article CAS PubMed Google Scholar
• Roberts, S.B., Savage, J., Coward, W.A., Chew, B., and Lucas, A.: Energy expenditure and intake in infants born to learn and overweight mothers. N Eng J Med 318: 461–466, 1988.
  Article CAS Google Scholar
• Robertson, E.J.: Pluripotent stem cell lines as a route into the mouse germ line. TIG (January): 9–13, 1986.
• Rohner-Jeanrenaud, F., and Jeanrenaud, B.: A role for the vagus nerve in the etiology and maintenance of the hyperinsulinemia of genetically obese falfa rats. Intl J Obesity 9: 71–75, 1985.
  Google Scholar
• Rohner-Jeanrenaud, F., Walker, C.-L., Greco-Perotto, R., and Jeanrenaud, B.: Central corticotropin-releasing factor administration prevents the excessive body weight gain of genetically obese (falfa) rats. Endocrinology 124: 733–739, 1989.
  Article CAS PubMed Google Scholar
• Rommens, J.M., Iannuzzi, M.C., Kerem, B., Drumm, M.L., Melmer, G., Dean, M., Rozmahel, R., Cole, J.L., Kennedy, D., Hidaka, N., Zsiga, M., Buchwald, M., Riordan, J.R., Tsui, L.-C., and Collins, F.S.: Identification of the cystic fibrosis gene: Chromosome walking and jumping. Science 245: 1059–1065, 1989.
  Article CAS PubMed Google Scholar
• Rosen, B.S., Cook, K.S., Yaglom, J., Groves, D.L., Volanakis, J.E., Damm, D., White, T., and Spiegelman, B.M.: Adipsin and the alternative pathway of complement in the regulation of energy balance. In G.A. Bray, D. Ricquier, and B.M. Spiegelman (eds.); Obesity: Towards a Molecular Approach, 273–287, Wiley-Liss, New York, 1990.
  Google Scholar
• Rutman, R.J., Lewis, F.S., and Bloomer, W.D.: Bispiperidyl mustard, a new obesifying agent in the mouse. Science 153: 1000–1002, 1966.
  Article CAS PubMed Google Scholar
• Sawchenko, P.E.: Evidence for a local site of action for glucocorticoids in inhibiting CRF and vasopressin expression in the paraventricular nucleus. Brain Res 403: 213–224, 1987.
  Article CAS PubMed Google Scholar
• Scambler, P.J., Law, H.-Y., Williamson, R., and Cooper, C.S.: Chromosome mediated gene transfer of six DNA markers linked to the cystic fibrosis locus on human Chromosome 7. Nucl Acids Res 14: 7159–7174, 1986.
  Article CAS PubMed Google Scholar
• Schlessinger, D.: Yeast artificial chromosomes: Tools for mapping and analysis of complex genomes. Trends Genet 6: 248–258, 1990.
  Article CAS PubMed Google Scholar
• Shor-Posner, G., Azar, A.P., Insinga, S., and Leibowitz, S.F.: Deficits in the control of food intake after hypothalamic paraventricular nucleus lesions. Physiol Behavior 35: 883–890, 1985.
  Article CAS Google Scholar
• Silverman, G.A., Jockel, J.I., Domer, P.H., Mohr, R.M., Taillon-Miller, P., and Korsmeyer, S.J.: Yeast artificial chromosome cloning of a two-megabase-size contig within chromosomal band 18q21 established physical linkage between BCL2 and plasminogen activator inhibitor type-2. Genomics 9: 219–228, 1991.
  Article CAS PubMed Google Scholar
• Sims, E.A., and Danforth, A.: Expenditure and storage of energy in man. J Clin Invest 79: 1019–1025, 1987.
  Article CAS PubMed Google Scholar
• Smith, D.R., Smyth, A.P., and Moir, D.T.: Amplification of large artificial chromosomes. Proc Natl Acad Sci USA 87: 8242–8246, 1990a.
  Article CAS PubMed Google Scholar
• Smith, G.P., Greenberg, D., Carp, E., and Gibbs, J.: Afferent information in the control of eating. In Obesity: Towards a Molecular Approach, 63–79, Wiley-Liss, New York, 1990b.
  Google Scholar
• Sorenson, T.I.A., Price, R.A., Stunkard, A.J., and Schulsinger, F.: Genetics of obesity in adult adoptess and their biological siblings. Br Med J 298: 87–90, 1989.
  Article Google Scholar
• Stunkard, A.J., Harris, J.R., Pedersen, N.L., and McClearn, G.E.: The body-mass index of twins who have been reared apart. N Engl J Med 322: 1483–1487, 1990.
  Article CAS PubMed Google Scholar
• Subhatme, P.V., and Margen, S.: Autoregulatory hemeostatic nature of energy balance. Am J Clin Nutr 35: 355–365, 1982.
  Google Scholar
• Thoday, J.M.: Location of polygenes. Nature 191: 368–370, 1961.
  Article Google Scholar
• Tomita, T., Doull, V., Kimmel, J.R., and Pollock, H.G.: Pancreatic polypeptide and other hormones in pancreas of obese (oblob) mice. Diabetologia 27: 454–459, 1984.
  Article CAS PubMed Google Scholar
• Tremblay, A., Poehlman, E.T., Nadeau, A., Dessault, J., and Bouchard, C.: Heredity and overfeeding-induced changes insubmaximal exercise VO2. J Appl Physiol 62: 539–544, 1987.
  CAS PubMed Google Scholar
• Truett, G.E., Bahary, N., Friedman, J.M., and Leibel, R.L.: The rat obesity gene fatty (fa) maps to Chromosome 5: Evidence for homology with mouse gene diabetes (db). Submitted, 1991.
• Wallace, M.R., Marchuk, D.A., Andersen, L.B., Letcher, R., Odeh, H.M., Saulino, A.M., Fountain, J.W., Brereton, A., Nicholson, J., Mitchell, A.L., Brownstein, B.H., and Collins, F.S.: Type I neurofibromatosis gene: Identification of a large transcript disrupted in three NF1 patients. Science 249: 181–186, 1990.
  Article CAS PubMed Google Scholar
• Weber, J.L., and May, P.E.: Abundant class of human DNA polymorphisms which can be typed using the polymerase chain reaction. Am J Hum Genet 44: 388–396, 1989.
  CAS PubMed Google Scholar
• Weigle, D.S.: Contribution of decreased body mass to diminished termic/effect of exercise in reduced-obese men. Int J Obesity 12: 567–578, 1988.
  CAS Google Scholar
• White, R., and Lalowel, J.M.: Investigation of genetic linkage in human families. Adv Human Genet 16: 121–228, 1987.
  CAS Google Scholar
• Wilson, B.E., Meyer, G.E., J.C. Cleveland, J., and Weigle, D.S.: Identification of candidate genes for a factor regulating body weight in primates. Am J Physiol, in press, 1991.
• York, D.A., Marchinton, D., Holt, S.J., and Allars, J.: Regulation of sympathetic activity in lean and obese Zucker (falfa) rats. Am J Physiol 249: 1985.

Download references