Cellular correlates of anxiety in CA1 hippocampal pyramidal cells of 5-HT1A receptor knockout mice (original) (raw)
Adhikari A, Topiwala MA, Gordon JA (2010) Synchronized activity between the ventral hippocampus and the medial prefrontal cortex during anxiety. Neuron 65:257–269 ArticleCASPubMed Google Scholar
Allan AM, Baier LD, Zhang X (1992) Effects of lorazepam tolerance and withdrawal on GABAA receptor-operated chloride channels. J Pharmacol Exp Ther 261:395–402 CASPubMed Google Scholar
Andrews N, Hogg S, Gonzalez LE, File SE (1994) 5-HT1A receptors in the median raphe nucleus and dorsal hippocampus may mediate anxiolytic and anxiogenic behaviours respectively. Eur J Pharmacol 264:259–264 ArticleCASPubMed Google Scholar
Appenrodt E, Kroning G, Schwarzberg H (1999) Increased plasma ACTH in rats exposed to the elevated plus-maze is independent of the pineal gland. Psychoneuroendocrinology 24:833–838 ArticleCASPubMed Google Scholar
Bailey SJ, Toth M (2004) Variability in the benzodiazepine response of serotonin 5-HT1A receptor null mice displaying anxiety-like phenotype: evidence for genetic modifiers in the 5-HT-mediated regulation of GABA(A) receptors. J Neurosci 24:6343–6351 ArticleCASPubMed Google Scholar
Barbaccia ML, Costa E, Ferrero P, Guidotti A, Roy A, Sunderland T, Pickar D, Paul SM, Goodwin FK (1986) Diazepam-binding inhibitor. A brain neuropeptide present in human spinal fluid: studies in depression, schizophrenia, and Alzheimer’s disease. Arch Gen Psychiatry 43:1143–1147 CASPubMed Google Scholar
Bourin M, Hascoet M (2001) Drug mechanisms in anxiety. Curr Opin Investig Drugs 2:259–265 CASPubMed Google Scholar
Britton KT, Lee G, Koob GF (1988) Corticotropin releasing factor and amphetamine exaggerate partial agonist properties of benzodiazepine antagonist Ro 15-1788 in the conflict test. Psychopharmacol (Berl) 94:306–311 CAS Google Scholar
Cagetti E, Liang J, Spigelman I, Olsen RW (2003) Withdrawal from chronic intermittent ethanol treatment changes subunit composition, reduces synaptic function, and decreases behavioral responses to positive allosteric modulators of GABAA receptors. Mol Pharmacol 63:53–64 ArticleCASPubMed Google Scholar
Calogero AE, Gallucci WT, Chrousos GP, Gold PW (1988) Interaction between GABAergic neurotransmission and rat hypothalamic corticotropin-releasing hormone secretion in vitro. Brain Res 463:28–36 ArticleCASPubMed Google Scholar
Carli M, Tatarczynska E, Cervo L, Samanin R (1993) Stimulation of hippocampal 5-HT1A receptors causes amnesia and anxiolytic-like but not antidepressant-like effects in the rat. Eur J Pharmacol 234:215–221 ArticleCASPubMed Google Scholar
Charney DS, Drevets WC (2002) Neurobiological basis of anxiety disorders. In: Davis KL, Charney DS, Coyle J, Nemeroff C (eds) Neuropsychopharmacology: the Fifth Generation of Progress. American College of Neuropsychopharmacology. Lippincott Williams & Wilkins, Baltimore, MD, pp 901–930 Google Scholar
Cossart R, Epsztein J, Tyzio R, Becq H, Hirsch J, Ben-Ari Y, Crepel V (2002) Quantal release of glutamate generates pure kainate and mixed AMPA/kainate EPSCs in hippocampal neurons. Neuron 35:147–159 ArticleCASPubMed Google Scholar
Costa E, Guidotti A (1991) Diazepam binding inhibitor (DBI): a peptide with multiple biological actions. Life Sci 49:325–344 ArticleCASPubMed Google Scholar
Crawley JN (1996) Unusual behavioral phenotypes of inbred mouse strains. Trends Neurosci 19:181–182 ArticleCASPubMed Google Scholar
Crawley J (2007) What’s wrong with my mouse: behavioral phenotyping of transgenic and knockout mice. John Wiley and Sons, Hoboken Google Scholar
Dos SL, De Andrade TG, Zangrossi JH (2008) 5-HT1A receptors in the dorsal hippocampus mediate the anxiogenic effect induced by the stimulation of 5-HT neurons in the median raphe nucleus. Eur Neuropsychopharmacol 18:286–294 Article Google Scholar
Fanselow MS, Dong HW (2010) Are the dorsal and ventral hippocampus functionally distinct structures? Neuron 65:7–19 ArticleCASPubMed Google Scholar
File SE (2001) Factors controlling measures of anxiety and responses to novelty in the mouse. Behav Brain Res 125:151–157 ArticleCASPubMed Google Scholar
File SE, Gonzalez LE (1996) Anxiolytic effects in the plus-maze of 5-HT1A-receptor ligands in dorsal raphe and ventral hippocampus. Pharmacol Biochem Behav 54:123–128 ArticleCASPubMed Google Scholar
File SE, Gonzalez LE, Andrews N (1996) Comparative study of pre- and postsynaptic 5-HT1A receptor modulation of anxiety in two ethological animal tests. J Neurosci 16:4810–4815 CASPubMed Google Scholar
File SE, Mabbutt PS, Hitchcott PK (1990) Characterisation of the phenomenon of “one-trial tolerance” to the anxiolytic effect of chlordiazepoxide in the elevated plus-maze. Psychopharmacol (Berl) 102:98–101 ArticleCAS Google Scholar
File SE, Zangrossi H Jr, Sanders FL, Mabbutt PS (1994) Raised corticosterone in the rat after exposure to the elevated plus-maze. Psychopharmacol (Berl) 113:543–546 ArticleCAS Google Scholar
Gerlai R (2001) Gene targeting: technical confounds and potential solutions in behavioral brain research. Behav Brain Res 125:13–21 ArticleCASPubMed Google Scholar
Gordon JA, Lacefield CO, Kentros CG, Hen R (2005) State-dependent alterations in hippocampal oscillations in serotonin 1A receptor-deficient mice. J Neurosci 25:6509–6519 ArticleCASPubMed Google Scholar
Graeff FG, Guimaraes FS, De Andrade TG, Deakin JF (1996) Role of 5-HT in stress, anxiety, and depression. Pharmacol Biochem Behav 54:129–141 ArticleCASPubMed Google Scholar
Gray JA, McNaughton N (2003) The neuropsychology of anxiety: an enquiry into the function of the septo-hippocampal system. Oxford University Press, Oxford Google Scholar
Griebel G, Moreau JL, Jenck F, Martin JR, Misslin R (1993) Some critical determinants of the behavior of rats in the elevated plus-maze. Behav Process 29:37–47 Article Google Scholar
Gross C, Zhuang X, Stark K, Ramboz S, Oosting R, Kirby L, Santarelli L, Beck S, Hen R (2002) Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult. Nature 416:396–400 ArticleCASPubMed Google Scholar
Heisler LK, Chu HM, Brennan TJ, Danao JA, Bajwa P, Parsons LH, Tecott LH (1998) Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice. Proc Natl Acad Sci USA 95:15049–15054 ArticleCASPubMed Google Scholar
Hogg S (1996) A review of the validity and variability of the elevated plus-maze as an animal model of anxiety. Pharmacol Biochem Behav 54:21–30 ArticleCASPubMed Google Scholar
Hogg S, Andrews N, File SE (1994) Contrasting behavioural effects of 8-OH DPAT in the dorsal raphe nucleus and ventral hippocampus. Neuropharmacology 33:343–348 ArticleCASPubMed Google Scholar
Jacobson L, Sapolsky RM (1991) The role of the hippocampus in feedback regulation of the hypothalamic-pituitary-adrenocortical axis. Endocr Rev 12:118–134 ArticleCASPubMed Google Scholar
Jolas T, Schreiber R, Laporte AM, Chastanet M, De VJ, Glaser T, Adrien J, Hamon M (1995) Are postsynaptic 5-HT1A receptors involved in the anxiolytic effects of 5-HT1A receptor agonists and in their inhibitory effects on the firing of serotonergic neurons in the rat? J Pharmacol Exp Ther 272:920–929 CASPubMed Google Scholar
Kataoka Y, Shibata K, Miyazaki A, Inoue Y, Tominaga K, Koizumi S, Ueki S, Niwa M (1991) Involvement of the dorsal hippocampus in mediation of the antianxiety action of tandospirone, a 5-hydroxytryptamine1A agonistic anxiolytic. Neuropharmacology 30:475–480 ArticleCASPubMed Google Scholar
Kostowski W, Plaznik A, Stefanski R (1989) Intra-hippocampal buspirone in animal models of anxiety. Eur J Pharmacol 168:393–396 ArticleCASPubMed Google Scholar
Lacaille JC, Mueller AL, Kunkel DD, Schwartzkroin PA (1987) Local circuit interactions between oriens/alveus interneurons and CA1 pyramidal cells in hippocampal slices: electrophysiology and morphology. J Neurosci 7:1979–1993 CASPubMed Google Scholar
Lister RG (1987) The use of a plus-maze to measure anxiety in the mouse. Psychopharmacol (Berl) 92:180–185 CAS Google Scholar
Lo IL, Gross C (2008) Alpha-Ca2+/calmodulin-dependent protein kinase II contributes to the developmental programming of anxiety in serotonin receptor 1A knock-out mice. J Neurosci 28:6250–6257 Article Google Scholar
Lucki I (1996) Serotonin receptor specificity in anxiety disorders. J Clin Psychiatry 57 Suppl 6:5–10 CASPubMed Google Scholar
Maguire JL, Stell BM, Rafizadeh M, Mody I (2005) Ovarian cycle-linked changes in GABA(A) receptors mediating tonic inhibition alter seizure susceptibility and anxiety. Nat Neurosci 8:797–804 ArticleCASPubMed Google Scholar
Mayorga AJ, Dalvi A, Page ME, Zimov-Levinson S, Hen R, Lucki I (2001) Antidepressant-like behavioral effects in 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) receptor mutant mice. J Pharmacol Exp Ther 298:1101–1107 CASPubMed Google Scholar
McEwen BS (2007) Physiology and neurobiology of stress and adaptation: central role of the brain. Physiol Rev 87:873–904 ArticlePubMed Google Scholar
McEwen BS, Gould EA, Sakai RR (1992) The vulnerability of the hippocampus to protective and destructive effects of glucocorticoids in relation to stress. Br J Psychiatry 15(Suppl):18–23 Google Scholar
McEwen BS, Magarinos AM (1997) Stress effects on morphology and function of the hippocampus. Ann NY Acad Sci 821:271–284 ArticleCASPubMed Google Scholar
Menard J, Treit D (1998) The septum and the hippocampus differentially mediate anxiolytic effects of R(+)-8-OH-DPAT. Behav Pharmacol 9:93–101 CASPubMed Google Scholar
Menard J, Treit D (1999) Effects of centrally administered anxiolytic compounds in animal models of anxiety. Neurosci Biobehav Rev 23:591–613 ArticleCASPubMed Google Scholar
Neumeister A, Bain E, Nugent AC, Carson RE, Bonne O, Luckenbaugh DA, Eckelman W, Herscovitch P, Charney DS, Drevets WC (2004) Reduced serotonin type 1A receptor binding in panic disorder. J Neurosci 24:589–591 ArticleCASPubMed Google Scholar
Parks CL, Robinson PS, Sibille E, Shenk T, Toth M (1998) Increased anxiety of mice lacking the serotonin1A receptor. Proc Natl Acad Sci USA 95:10734–10739 ArticleCASPubMed Google Scholar
Pattij T, Groenink L, Oosting RS, van der GJ M, RA OB (2002) GABA(A)-benzodiazepine receptor complex sensitivity in 5-HT(1A) receptor knockout mice on a 129/Sv background. Eur J Pharmacol 447:67–74 ArticleCASPubMed Google Scholar
Pellow S, Chopin P, File SE, Briley M (1985) Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods 14:149–167 ArticleCASPubMed Google Scholar
Phillips TJ, Hen R, Crabbe JC (1999) Complications associated with genetic background effects in research using knockout mice. Psychopharmacol (Berl) 147:5–7 ArticleCAS Google Scholar
Ramboz S, Oosting R, Amara DA, Kung HF, Blier P, Mendelsohn M, Mann JJ, Brunner D, Hen R (1998) Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. Proc Natl Acad Sci USA 95:14476–14481 ArticleCASPubMed Google Scholar
Ravindran LN, Stein MB (2010) The pharmacologic treatment of anxiety disorders: a review of progress. J Clin Psychiatry 71:839–854 ArticleCASPubMed Google Scholar
Rodgers RJ, Haller J, Holmes A, Halasz J, Walton TJ, Brain PF (1999) Corticosterone response to the plus-maze: high correlation with risk assessment in rats and mice. Physiol Behav 68:47–53 ArticleCASPubMed Google Scholar
Rodgers RJ, Lee C, Shepherd JK (1992) Effects of diazepam on behavioural and antinociceptive responses to the elevated plus-maze in male mice depend upon treatment regimen and prior maze experience. Psychopharmacol (Berl) 106:102–110 ArticleCAS Google Scholar
Rodgers RJ, Shepherd JK (1993) Influence of prior maze experience on behaviour and response to diazepam in the elevated plus-maze and light/dark tests of anxiety in mice. Psychopharmacol (Berl) 113:237–242 ArticleCAS Google Scholar
Sandford JJ, Argyropoulos SV, Nutt DJ (2000) The psychobiology of anxiolytic drugs. Part 1: Basic neurobiology. Pharmacol Ther 88:197–212 ArticleCASPubMed Google Scholar
Sarnyai Z, Sibille EL, Pavlides C, Fenster RJ, McEwen BS, Toth M (2000) Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors. Proc Natl Acad Sci USA 97:14731–14736 ArticleCASPubMed Google Scholar
Schreiber R, De Vry J (1993) Neuronal circuits involved in the anxiolytic effects of the 5-HT1A receptor agonists 8-OH-DPAT ipsapirone and buspirone in the rat. Eur J Pharmacol 249:341–351 ArticleCASPubMed Google Scholar
Sibille E, Pavlides C, Benke D, Toth M (2000) Genetic inactivation of the Serotonin(1A) receptor in mice results in downregulation of major GABA(A) receptor alpha subunits, reduction of GABA(A) receptor binding, and benzodiazepine-resistant anxiety. J Neurosci 20:2758–2765 CASPubMed Google Scholar
Skelton KH, Nemeroff CB, Knight DL, Owens MJ (2000) Chronic administration of the triazolobenzodiazepine alprazolam produces opposite effects on corticotropin-releasing factor and urocortin neuronal systems. J Neurosci 20:1240–1248 CASPubMed Google Scholar
Smith SS, Gong QH, Li X, Moran MH, Bitran D, Frye CA, Hsu FC (1998) Withdrawal from 3alpha-OH-5alpha-pregnan-20-One using a pseudopregnancy model alters the kinetics of hippocampal GABAA-gated current and increases the GABAA receptor alpha4 subunit in association with increased anxiety. J Neurosci 18:5275–5284 CASPubMed Google Scholar
Stefanski R, Palejko W, Bidzinski A, Kostowski W, Plaznik A (1993) Serotonergic innervation of the hippocampus and nucleus accumbens septi and the anxiolytic-like action of midazolam and 5-HT1A receptor agonists. Neuropharmacology 32:977–985 ArticleCASPubMed Google Scholar
Treit D, Menard J, Royan C (1993) Anxiogenic stimuli in the elevated plus-maze. Pharmacol Biochem Behav 44:463–469 ArticleCASPubMed Google Scholar
Van Sickle BJ, Xiang K, Tietz EI (2004) Transient plasticity of hippocampal CA1 neuron glutamate receptors contributes to benzodiazepine withdrawal-anxiety. Neuropsychopharmacology 29:1994–2006 ArticlePubMed Google Scholar