Seth Barishansky | Rutgers Robert Wood Johnson Medical School (original) (raw)
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Papers by Seth Barishansky
Fertility and Sterility, Apr 1, 2020
Between January 1976 and August 2001, endometrial samples from 87 women who underwent endometrial... more Between January 1976 and August 2001, endometrial samples from 87 women who underwent endometrial biopsy for abnormal uterine bleeding at the authors' institution were reported as "inadequate." The medical records of 76 women were suitable for review and were used to investigate the negative predictive value of inadequate endometrial specimens. Mean follow up was 26 months (range, 0-60 months). Follow-up management varied from observation to further diagnostic biopsy or ultrasound, or to treatment with hysteroscopy, dilation and curettage, or hysterectomy (Fig. 1). Fifty-five women were postmenopausal and 21 were premenopausal (mean age, 55 years). Follow-up tissue diagnoses were available for 37 women. In these patients, there was 1 histologic diagnosis of complex hyperplasia without atypia. Among the 38 women without follow-up tissue diagnoses, there were no reports of further bleeding.
Fertility and Sterility, Jul 1, 2023
Fertility and Sterility, Oct 1, 2022
Fertility and Sterility, Feb 1, 2023
Journal of Assisted Reproduction and Genetics
Fertility and Sterility, 2020
Fertility and Sterility, 2020
Objective: To evaluate the available COVID-19 content in regard to fertility care on the websites... more Objective: To evaluate the available COVID-19 content in regard to fertility care on the websites of Society for Assisted Reproductive Technology (SART) member clinics Design: Cross-sectional study Materials and Methods: From March 17 to March 30, 2020, following the release of the first American Society for Reproductive Medicine (ASRM) COVID-19 recommendations, SART member clinics’ websites were examined The presence of information on COVID-19 and pregnancy implications, acknowledgement of and compliance with ASRM recommendations, description of Centers for Disease Control and Prevention (CDC) risk mitigation strategies and local health department guidelines, as well as advertisement of telehealth and available mental health resources were queried Websites were categorized by practice size (small: <500 vs large: ≥500 cycles/year), type (academic vs private) and degree of statewide COVID-19 burden based on CDC data (low: 0-1000;high: ≥1000 diagnosed cases) Group differences were ...
International Journal of Molecular Sciences, 2021
The female reproductive system ages before any other organ system in the body. This phenomenon ca... more The female reproductive system ages before any other organ system in the body. This phenomenon can have tangible clinical implications leading to infertility, miscarriages, birth defects and systemic deterioration due to estrogen loss. “Fibroinflammation” is a hallmark of aging tissues; there is an increase in inflammatory cytokines and fibrotic tissue in the aging ovarian stroma. We systematically evaluated immunomodulatory factors in human follicular fluid, which, like the stroma, is a critical ovarian microenvironment directly influencing the oocyte. Using a cytokine antibody array, we identified a unique fibroinflammatory cytokine signature in follicular fluid across an aging series of women (27.7–44.8 years). This signature (IL-3, IL-7, IL-15, TGFβ1, TGFβ3 and MIP-1) increased with chronologic age, was inversely correlated to anti-Müllerian hormone (AMH) levels, and was independent of body mass index (BMI). We focused on one specific protein, TGFβ3, for further validation. By i...
Objective: To evaluate the available COVID-19 content in regard to fertility care on the social m... more Objective: To evaluate the available COVID-19 content in regard to fertility care on the social media (SM) platforms from Society for Assisted Reproductive Technology (SART) member clinics Design: Cross-sectional study Materials and Methods: From March 17-30/2020, following the release of the first American Society for Reproductive Medicine (ASRM) COVID-19 recommendations, SART member clinics’ SM platforms including Facebook and Twitter were examined The presence of information on COVID-19, its pregnancy implications, acknowledgement of and compliance with ASRM recommendations, mention of Centers for Disease Control and Prevention (CDC) risk mitigation strategies and local health department guidelines, as well as advertisement for telehealth and availability of mental health resources were queried Websites were categorized by practice size (<500 vs ≥500 cycles/year), type (academic vs private) and degree of statewide COVID-19 burden based on CDC surveillance data (low: 0-1000;hig...
JSLS : Journal of the Society of Laparoscopic & Robotic Surgeons
Background:Malnutrition continues to be pervasive among the general population, with rates as hig... more Background:Malnutrition continues to be pervasive among the general population, with rates as high as 50% of patients undergoing surgical procedures. Data is limited about women undergoing surgery for non-malignant gynecologic indications (generally elective laparoscopic hysterectomies, after failed conservative measures). With the significant increase in benign gynecologic surgery, it is of the upmost importance that surgeons optimize modifiable risk factors for patients undergoing laparoscopic hysterectomy. The purpose of this study is to identify the impact of malnutrition on postoperative outcomes in patients undergoing laparoscopic hysterectomy for benign conditions.Methods:A retrospective cohort study was conducted utilizing data that was collected through the American College of Surgeon’s National Surgical Quality Improvement Program (NSQIP) Database. All patients that underwent laparoscopic hysterectomy for benign indications were identified. Patients with malnutrition were identified by either low albumin (≤ 3.5 g/dL), low body mass index (≤ 18.5), or 10% weight loss within 6 months. The frequency of postoperative complications was evaluated with univariate and multivariate analyses where appropriate.Results:Following adjustment, multivariate analysis illustrated pre-operative malnutrition to be a risk factor for the following complications: any complication, death, bleeding requiring transfusion, wound, cardiac, pulmonary, renal, thromboembolic, sepsis complications, extended length of stay, and reoperation (p ≤ 0.05 for all).Conclusion:Malnourished patients were at significantly higher risk of developing postoperative complications during the acute postoperative period. With elective laparoscopic hysterectomies, pre-operative evaluation and intervention for malnutrition should be considered to improve nutritional status.
American Journal of Psychiatry Residents' Journal
Fertility and Sterility, Apr 1, 2020
Between January 1976 and August 2001, endometrial samples from 87 women who underwent endometrial... more Between January 1976 and August 2001, endometrial samples from 87 women who underwent endometrial biopsy for abnormal uterine bleeding at the authors' institution were reported as "inadequate." The medical records of 76 women were suitable for review and were used to investigate the negative predictive value of inadequate endometrial specimens. Mean follow up was 26 months (range, 0-60 months). Follow-up management varied from observation to further diagnostic biopsy or ultrasound, or to treatment with hysteroscopy, dilation and curettage, or hysterectomy (Fig. 1). Fifty-five women were postmenopausal and 21 were premenopausal (mean age, 55 years). Follow-up tissue diagnoses were available for 37 women. In these patients, there was 1 histologic diagnosis of complex hyperplasia without atypia. Among the 38 women without follow-up tissue diagnoses, there were no reports of further bleeding.
Fertility and Sterility, Jul 1, 2023
Fertility and Sterility, Oct 1, 2022
Fertility and Sterility, Feb 1, 2023
Journal of Assisted Reproduction and Genetics
Fertility and Sterility, 2020
Fertility and Sterility, 2020
Objective: To evaluate the available COVID-19 content in regard to fertility care on the websites... more Objective: To evaluate the available COVID-19 content in regard to fertility care on the websites of Society for Assisted Reproductive Technology (SART) member clinics Design: Cross-sectional study Materials and Methods: From March 17 to March 30, 2020, following the release of the first American Society for Reproductive Medicine (ASRM) COVID-19 recommendations, SART member clinics’ websites were examined The presence of information on COVID-19 and pregnancy implications, acknowledgement of and compliance with ASRM recommendations, description of Centers for Disease Control and Prevention (CDC) risk mitigation strategies and local health department guidelines, as well as advertisement of telehealth and available mental health resources were queried Websites were categorized by practice size (small: <500 vs large: ≥500 cycles/year), type (academic vs private) and degree of statewide COVID-19 burden based on CDC data (low: 0-1000;high: ≥1000 diagnosed cases) Group differences were ...
International Journal of Molecular Sciences, 2021
The female reproductive system ages before any other organ system in the body. This phenomenon ca... more The female reproductive system ages before any other organ system in the body. This phenomenon can have tangible clinical implications leading to infertility, miscarriages, birth defects and systemic deterioration due to estrogen loss. “Fibroinflammation” is a hallmark of aging tissues; there is an increase in inflammatory cytokines and fibrotic tissue in the aging ovarian stroma. We systematically evaluated immunomodulatory factors in human follicular fluid, which, like the stroma, is a critical ovarian microenvironment directly influencing the oocyte. Using a cytokine antibody array, we identified a unique fibroinflammatory cytokine signature in follicular fluid across an aging series of women (27.7–44.8 years). This signature (IL-3, IL-7, IL-15, TGFβ1, TGFβ3 and MIP-1) increased with chronologic age, was inversely correlated to anti-Müllerian hormone (AMH) levels, and was independent of body mass index (BMI). We focused on one specific protein, TGFβ3, for further validation. By i...
Objective: To evaluate the available COVID-19 content in regard to fertility care on the social m... more Objective: To evaluate the available COVID-19 content in regard to fertility care on the social media (SM) platforms from Society for Assisted Reproductive Technology (SART) member clinics Design: Cross-sectional study Materials and Methods: From March 17-30/2020, following the release of the first American Society for Reproductive Medicine (ASRM) COVID-19 recommendations, SART member clinics’ SM platforms including Facebook and Twitter were examined The presence of information on COVID-19, its pregnancy implications, acknowledgement of and compliance with ASRM recommendations, mention of Centers for Disease Control and Prevention (CDC) risk mitigation strategies and local health department guidelines, as well as advertisement for telehealth and availability of mental health resources were queried Websites were categorized by practice size (<500 vs ≥500 cycles/year), type (academic vs private) and degree of statewide COVID-19 burden based on CDC surveillance data (low: 0-1000;hig...
JSLS : Journal of the Society of Laparoscopic & Robotic Surgeons
Background:Malnutrition continues to be pervasive among the general population, with rates as hig... more Background:Malnutrition continues to be pervasive among the general population, with rates as high as 50% of patients undergoing surgical procedures. Data is limited about women undergoing surgery for non-malignant gynecologic indications (generally elective laparoscopic hysterectomies, after failed conservative measures). With the significant increase in benign gynecologic surgery, it is of the upmost importance that surgeons optimize modifiable risk factors for patients undergoing laparoscopic hysterectomy. The purpose of this study is to identify the impact of malnutrition on postoperative outcomes in patients undergoing laparoscopic hysterectomy for benign conditions.Methods:A retrospective cohort study was conducted utilizing data that was collected through the American College of Surgeon’s National Surgical Quality Improvement Program (NSQIP) Database. All patients that underwent laparoscopic hysterectomy for benign indications were identified. Patients with malnutrition were identified by either low albumin (≤ 3.5 g/dL), low body mass index (≤ 18.5), or 10% weight loss within 6 months. The frequency of postoperative complications was evaluated with univariate and multivariate analyses where appropriate.Results:Following adjustment, multivariate analysis illustrated pre-operative malnutrition to be a risk factor for the following complications: any complication, death, bleeding requiring transfusion, wound, cardiac, pulmonary, renal, thromboembolic, sepsis complications, extended length of stay, and reoperation (p ≤ 0.05 for all).Conclusion:Malnourished patients were at significantly higher risk of developing postoperative complications during the acute postoperative period. With elective laparoscopic hysterectomies, pre-operative evaluation and intervention for malnutrition should be considered to improve nutritional status.
American Journal of Psychiatry Residents' Journal