Kwang Jung • UCI Profiles (original) (raw)

  1. Chronic cannabis use in people with bipolar disorder is associated with comparable decision-making and functional outcome to healthy participants. Transl Psychiatry. 2025 Nov 27; 15(1):506. Miranda A, Roberts BZ, Holloway BM, Peek E, Rosberg H, Ayoub SM, Piomelli D, Jung KM, Barnes SA, Rossi S, Geyer MA, Perry W, Minassian A, Young JW. PMID: 41309543; PMCID: PMC12660854.
    View in: PubMed Mentions: Fields:
    Translation:Humans
  2. Adolescent exposure to Δ9-tetrahydrocannabinol impairs testicular function in young adult male mice. Toxicol Sci. 2025 Nov 01; 208(1):82-94. Lim J, Quach C, Nguyen J, Rizk A, Getze S, Jung KM, Mahler SV, Piomelli D, Luderer U. PMID: 40127192; PMCID: PMC12599868.
    View in: PubMed Mentions: Fields:
    Translation:Animals
  3. Metabolic reprogramming in the spinal cord drives the transition to pain chronicity. Cell Rep. 2025 Sep 23; 44(9):116261. Mabou Tagne A, Fotio Y, Lee HL, Jung KM, Katz J, Ahmed F, Le J, Bazinet R, Jang C, Piomelli D. PMID: 40946312; PMCID: PMC12717780.
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    Translation:Animals
  4. Administration of Δ9-Tetrahydrocannabinol (THC) in Adolescent and Adult Mice. J Vis Exp. 2025 Aug 01; (222). Jung KM, Mabou Tagne A, Avalos HC, D'Agosta D, Katz J, Lee HL, Piomelli D. PMID: 40824853.
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    Translation:Animals
  5. Microglia Support Both the Singular Form of LTP Expressed by the Lateral Perforant Path and Episodic Memory. J Neurosci. 2025 06 25; 45(26). Chavez J, Le AA, Quintanilla J, Lauterborn JC, Jia Y, Tagne AM, Lee HL, Jung KM, Piomelli D, Lynch G, Gall CM. PMID: 40404354; PMCID: PMC12199551.
    View in: PubMed Mentions: 1 Fields:
    Translation:AnimalsCells
  6. Metabolic reprogramming in the spinal cord drives the transition to pain chronicity. bioRxiv. 2025 Jun 19. Tagne AM, Fotio Y, Lee HL, Jung KM, Katz J, Ahmed F, Le J, Bazinet R, Jang C, Piomelli D. PMID: 39975205; PMCID: PMC11838349.
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  7. Targeting dysfunctional endocannabinoid signaling in a mouse model of Gulf War illness. Neuropharmacology. 2024 Dec 15; 261:110142. Squire E, Lee HL, Jeong W, Lee S, Ravichandiran V, Limoli CL, Piomelli D, Parihar VK, Jung KM. PMID: 39241906.
    View in: PubMed Mentions: Fields:
    Translation:AnimalsCells
  8. Overactivation of the Endocannabinoid System in Adolescence Disrupts Adult Adipose Organ Function in Mice. Cells. 2024 03 06; 13(5). Jung KM, Lin L, Piomelli D. PMID: 38474425; PMCID: PMC10930932.
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    Translation:HumansAnimalsCells
  9. Development of Potent and Selective Monoacylglycerol Lipase Inhibitors. SARs, Structural Analysis, and Biological Characterization. J Med Chem. 2024 02 08; 67(3):1758-1782. Butini S, Grether U, Jung KM, Ligresti A, Allarà M, Postmus AGJ, Maramai S, Brogi S, Papa A, Carullo G, Sykes D, Veprintsev D, Federico S, Grillo A, Di Guglielmo B, Ramunno A, Stevens AF, Heer D, Lamponi S, Gemma S, Benz J, Di Marzo V, van der Stelt M, Piomelli D, Campiani G. PMID: 38241614.
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    Translation:Animals
  10. Frequent low-impact exposure to THC during adolescence causes persistent sexually dimorphic alterations in the response to viral infection in mice. Pharmacol Res. 2024 Jan; 199:107049. Lee HL, Squire E, Fotio Y, Mabou Tagne A, Lee J, Yoon JJ, Hong Y, Kim LH, Jung KM, Piomelli D. PMID: 38159785.
    View in: PubMed Mentions: 4 Fields:
    Translation:AnimalsCells
  11. Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood. Cell Metab. 2023 07 11; 35(7):1227-1241.e7. Lin L, Jung KM, Lee HL, Le J, Colleluori G, Wood C, Palese F, Squire E, Ramirez J, Su S, Torrens A, Fotio Y, Tang L, Yu C, Yang Q, Huang L, DiPatrizio N, Jang C, Cinti S, Piomelli D. PMID: 37267956; PMCID: PMC10524841.
    View in: PubMed Mentions: 14 Fields:
    Translation:Animals
  12. Adolescent exposure to low-dose Δ9-tetrahydrocannabinol depletes the ovarian reserve in female mice. Toxicol Sci. 2023 05 12; 193(1):31-47. Lim J, Lee HL, Nguyen J, Shin J, Getze S, Quach C, Squire E, Jung KM, Mahler SV, Mackie K, Piomelli D, Luderer U. PMID: 36912754; PMCID: PMC10176244.
    View in: PubMed Mentions: 3 Fields:
    Translation:Animals
  13. Fatty acid amide hydrolase inhibition alleviates anxiety-like symptoms in a rat model used to study post-traumatic stress disorder. Psychopharmacology (Berl). 2025 Jul; 242(7):1541-1551. Fotio Y, Mabou Tagne A, Jung KM, Piomelli D. PMID: 37017699.
    View in: PubMed Mentions: 10 Fields:
    Translation:Animals
  14. Assay of Monoacylglycerol Lipase Activity. Methods Mol Biol. 2023; 2576:285-297. Jung KM, Piomelli D. PMID: 36152196.
    View in: PubMed Mentions: 4 Fields:
  15. Phytocannabinoids, the Endocannabinoid System and Male Reproduction. World J Mens Health. 2023 Jan; 41(1):1-10. Lim J, Squire E, Jung KM. PMID: 36578200; PMCID: PMC9826913.
    View in: PubMed Mentions: 8
  16. Frequent Low-Dose Δ9-Tetrahydrocannabinol in Adolescence Disrupts Microglia Homeostasis and Disables Responses to Microbial Infection and Social Stress in Young Adulthood. Biol Psychiatry. 2022 12 01; 92(11):845-860. Lee HL, Jung KM, Fotio Y, Squire E, Palese F, Lin L, Torrens A, Ahmed F, Mabou Tagne A, Ramirez J, Su S, Wong CR, Jung DH, Scarfone VM, Nguyen PU, Wood M, Green K, Piomelli D. PMID: 35750512; PMCID: PMC10629396.
    View in: PubMed Mentions: 20 Fields:
    Translation:AnimalsCells
  17. NAAA-regulated lipid signaling governs the transition from acute to chronic pain. Sci Adv. 2021 Oct 22; 7(43):eabi8834. Fotio Y, Jung KM, Palese F, Obenaus A, Tagne AM, Lin L, Rashid TI, Pacheco R, Jullienne A, Ramirez J, Mor M, Spadoni G, Jang C, Hohmann AG, Piomelli D. PMID: 34678057; PMCID: PMC8535814.
    View in: PubMed Mentions: 16 Fields:
  18. Ceramide contributes to pathogenesis and may be targeted for therapy in VCP inclusion body myopathy. Hum Mol Genet. 2021 02 25; 29(24):3945-3953. Weiss L, Jung KM, Nalbandian A, Llewellyn K, Yu H, Ta L, Chang I, Migliore M, Squire E, Ahmed F, Piomelli D, Kimonis V. PMID: 33410456; PMCID: PMC8485215.
    View in: PubMed Mentions: 7 Fields:
    Translation:HumansAnimalsCells
  19. The endocannabinoid system in the adipose organ. Rev Endocr Metab Disord. 2022 02; 23(1):51-60. Jung KM, Lin L, Piomelli D. PMID: 33387286; PMCID: PMC8776163.
    View in: PubMed Mentions: 11 Fields:
    Translation:HumansAnimals
  20. Cannabinoids in periodontal disease amid the COVID-19 pandemic. J Periodontal Implant Sci. 2020 Dec; 50(6):355-357. Park JB, Jung KM, Piomelli D. PMID: 33350175; PMCID: PMC7758300.
    View in: PubMed Mentions: 1
  21. Benzisothiazolinone Derivatives as Potent Allosteric Monoacylglycerol Lipase Inhibitors That Functionally Mimic Sulfenylation of Regulatory Cysteines. J Med Chem. 2020 02 13; 63(3):1261-1280. Castelli R, Scalvini L, Vacondio F, Lodola A, Anselmi M, Vezzosi S, Carmi C, Bassi M, Ferlenghi F, Rivara S, Møller IR, Rand KD, Daglian J, Wei D, Dotsey EY, Ahmed F, Jung KM, Stella N, Singh S, Mor M, Piomelli D. PMID: 31714779.
    View in: PubMed Mentions: 3 Fields:
    Translation:HumansAnimalsCells
  22. Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit. J Med Chem. 2018 09 13; 61(17):7902-7916. Spadoni G, Bedini A, Furiassi L, Mari M, Mor M, Scalvini L, Lodola A, Ghidini A, Lucini V, Dugnani S, Scaglione F, Piomelli D, Jung KM, Supuran CT, Lucarini L, Durante M, Sgambellone S, Masini E, Rivara S. PMID: 30126274.
    View in: PubMed Mentions: 6 Fields:
    Translation:AnimalsCells
  23. Atypical Endocannabinoid Signaling Initiates a New Form of Memory-Related Plasticity at a Cortical Input to Hippocampus. Cereb Cortex. 2018 07 01; 28(7):2253-2266. Wang W, Jia Y, Pham DT, Palmer LC, Jung KM, Cox CD, Rumbaugh G, Piomelli D, Gall CM, Lynch G. PMID: 28520937; PMCID: PMC5998949.
    View in: PubMed Mentions: 30 Fields:
    Translation:AnimalsCells
  24. Dysfunctional oleoylethanolamide signaling in a mouse model of Prader-Willi syndrome. Pharmacol Res. 2017 03; 117:75-81. Igarashi M, Narayanaswami V, Kimonis V, Galassetti PM, Oveisi F, Jung KM, Piomelli D. PMID: 28007570; PMCID: PMC5922435.
    View in: PubMed Mentions: 9 Fields:
    Translation:AnimalsCells
  25. Neurophysiology of space travel: energetic solar particles cause cell type-specific plasticity of neurotransmission. Brain Struct Funct. 2017 Jul; 222(5):2345-2357. Lee SH, Dudok B, Parihar VK, Jung KM, Zöldi M, Kang YJ, Maroso M, Alexander AL, Nelson GA, Piomelli D, Katona I, Limoli CL, Soltesz I. PMID: 27905022; PMCID: PMC5504243.
    View in: PubMed Mentions: 30 Fields:
    Translation:AnimalsCells
  26. Free-energy studies reveal a possible mechanism for oxidation-dependent inhibition of MGL. Sci Rep. 2016 08 08; 6:31046. Scalvini L, Vacondio F, Bassi M, Pala D, Lodola A, Rivara S, Jung KM, Piomelli D, Mor M. PMID: 27499063; PMCID: PMC4976315.
    View in: PubMed Mentions: 6 Fields:
    Translation:HumansCells
  27. A Primary Cortical Input to Hippocampus Expresses a Pathway-Specific and Endocannabinoid-Dependent Form of Long-Term Potentiation. eNeuro. 2016 Jul-Aug; 3(4). Wang W, Trieu BH, Palmer LC, Jia Y, Pham DT, Jung KM, Karsten CA, Merrill CB, Mackie K, Gall CM, Piomelli D, Lynch G. PMID: 27517090; PMCID: PMC4976302.
    View in: PubMed Mentions: 51 Fields:
    Translation:AnimalsCells
  28. Second-Generation Non-Covalent NAAA Inhibitors are Protective in a Model of Multiple Sclerosis. Angew Chem Int Ed Engl. 2016 09 05; 55(37):11193-11197. Migliore M, Pontis S, Fuentes de Arriba AL, Realini N, Torrente E, Armirotti A, Romeo E, Di Martino S, Russo D, Pizzirani D, Summa M, Lanfranco M, Ottonello G, Busquet P, Jung KM, Garcia-Guzman M, Heim R, Scarpelli R, Piomelli D. PMID: 27404798; PMCID: PMC5009002.
    View in: PubMed Mentions: 21 Fields:
    Translation:AnimalsCells
  29. Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain. J Med Chem. 2016 03 24; 59(6):2612-32. Brindisi M, Maramai S, Gemma S, Brogi S, Grillo A, Di Cesare Mannelli L, Gabellieri E, Lamponi S, Saponara S, Gorelli B, Tedesco D, Bonfiglio T, Landry C, Jung KM, Armirotti A, Luongo L, Ligresti A, Piscitelli F, Bertucci C, Dehouck MP, Campiani G, Maione S, Ghelardini C, Pittaluga A, Piomelli D, Di Marzo V, Butini S. PMID: 26888301.
    View in: PubMed Mentions: 30 Fields:
    Translation:HumansAnimalsCells
  30. A role for the endocannabinoid 2-arachidonoyl-sn-glycerol for social and high-fat food reward in male mice. Psychopharmacology (Berl). 2016 05; 233(10):1911-9. Wei D, Lee D, Li D, Daglian J, Jung KM, Piomelli D. PMID: 26873082; PMCID: PMC5118226.
    View in: PubMed Mentions: 22 Fields:
    Translation:AnimalsCells
  31. Assay of Monoacylglycerol Lipase Activity. Methods Mol Biol. 2016; 1412:157-68. Jung KM, Piomelli D. PMID: 27245902.
    View in: PubMed Mentions: 1 Fields:
    Translation:HumansAnimalsCells
  32. Endocannabinoid Modulation of Predator Stress-Induced Long-Term Anxiety in Rats. Neuropsychopharmacology. 2016 Apr; 41(5):1329-39. Lim J, Igarashi M, Jung KM, Butini S, Campiani G, Piomelli D. PMID: 26361059; PMCID: PMC4793117.
    View in: PubMed Mentions: 26 Fields:
    Translation:Animals
  33. Fasting stimulates 2-AG biosynthesis in the small intestine: role of cholinergic pathways. Am J Physiol Regul Integr Comp Physiol. 2015 Oct 15; 309(8):R805-13. DiPatrizio NV, Igarashi M, Narayanaswami V, Murray C, Gancayco J, Russell A, Jung KM, Piomelli D. PMID: 26290104; PMCID: PMC4666947.
    View in: PubMed Mentions: 28 Fields:
    Translation:Animals
  34. Peroxide-Dependent MGL Sulfenylation Regulates 2-AG-Mediated Endocannabinoid Signaling in Brain Neurons. Chem Biol. 2015 May 21; 22(5):619-28. Dotsey EY, Jung KM, Basit A, Wei D, Daglian J, Vacondio F, Armirotti A, Mor M, Piomelli D. PMID: 26000748; PMCID: PMC4459529.
    View in: PubMed Mentions: 17 Fields:
    Translation:HumansAnimalsCells
  35. O-(triazolyl)methyl carbamates as a novel and potent class of fatty acid amide hydrolase (FAAH) inhibitors. ChemMedChem. 2015 Feb; 10(2):380-95. Colombano G, Albani C, Ottonello G, Ribeiro A, Scarpelli R, Tarozzo G, Daglian J, Jung KM, Piomelli D, Bandiera T. PMID: 25338703; PMCID: PMC4384654.
    View in: PubMed Mentions: 7 Fields:
    Translation:HumansAnimalsCells
  36. Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease. Hum Mol Genet. 2014 Mar 01; 23(5):1333-44. Llewellyn KJ, Nalbandian A, Jung KM, Nguyen C, Avanesian A, Mozaffar T, Piomelli D, Kimonis VE. PMID: 24158850; PMCID: PMC3919004.
    View in: PubMed Mentions: 13 Fields:
    Translation:AnimalsCells
  37. Endocannabinoid signaling in the gut mediates preference for dietary unsaturated fats. FASEB J. 2013 Jun; 27(6):2513-20. DiPatrizio NV, Joslin A, Jung KM, Piomelli D. PMID: 23463697; PMCID: PMC3659363.
    View in: PubMed Mentions: 37 Fields:
    Translation:AnimalsCells
  38. Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia. J Neurosci. 2012 Jul 11; 32(28):9457-68. Gregg LC, Jung KM, Spradley JM, Nyilas R, Suplita RL, Zimmer A, Watanabe M, Mackie K, Katona I, Piomelli D, Hohmann AG. PMID: 22787031; PMCID: PMC3652685.
    View in: PubMed Mentions: 36 Fields:
    Translation:AnimalsCells
  39. 2-arachidonoylglycerol signaling in forebrain regulates systemic energy metabolism. Cell Metab. 2012 Mar 07; 15(3):299-310. Jung KM, Clapper JR, Fu J, D'Agostino G, Guijarro A, Thongkham D, Avanesian A, Astarita G, DiPatrizio NV, Frontini A, Cinti S, Diano S, Piomelli D. PMID: 22405068; PMCID: PMC3729112.
    View in: PubMed Mentions: 53 Fields:
    Translation:AnimalsCells
  40. Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome. Nat Commun. 2012; 3:1080. Jung KM, Sepers M, Henstridge CM, Lassalle O, Neuhofer D, Martin H, Ginger M, Frick A, DiPatrizio NV, Mackie K, Katona I, Piomelli D, Manzoni OJ. PMID: 23011134; PMCID: PMC3657999.
    View in: PubMed Mentions: 146 Fields:
    Translation:AnimalsCells
  41. Elevated stearoyl-CoA desaturase in brains of patients with Alzheimer's disease. PLoS One. 2011; 6(10):e24777. Astarita G, Jung KM, Vasilevko V, Dipatrizio NV, Martin SK, Cribbs DH, Head E, Cotman CW, Piomelli D. PMID: 22046234; PMCID: PMC3202527.
    View in: PubMed Mentions: 61 Fields:
    Translation:Humans
  42. An amyloid β42-dependent deficit in anandamide mobilization is associated with cognitive dysfunction in Alzheimer's disease. Neurobiol Aging. 2012 Aug; 33(8):1522-32. Jung KM, Astarita G, Yasar S, Vasilevko V, Cribbs DH, Head E, Cotman CW, Piomelli D. PMID: 21546126; PMCID: PMC3154439.
    View in: PubMed Mentions: 47 Fields:
    Translation:Humans
  43. Diacylglycerol lipase-alpha and -beta control neurite outgrowth in neuro-2a cells through distinct molecular mechanisms. Mol Pharmacol. 2011 Jul; 80(1):60-7. Jung KM, Astarita G, Thongkham D, Piomelli D. PMID: 21493725; PMCID: PMC3127538.
    View in: PubMed Mentions: 19 Fields:
    Translation:HumansCells
  44. Deficient liver biosynthesis of docosahexaenoic acid correlates with cognitive impairment in Alzheimer's disease. PLoS One. 2010 Sep 08; 5(9):e12538. Astarita G, Jung KM, Berchtold NC, Nguyen VQ, Gillen DL, Head E, Cotman CW, Piomelli D. PMID: 20838618; PMCID: PMC2935886.
    View in: PubMed Mentions: 91 Fields:
    Translation:Humans
  45. Purification of neutral sphingomyelinase 2 from bovine brain and its calcium-dependent activation. J Neurochem. 2010 Feb; 112(4):1088-97. Kim SK, Ahn KH, Jeon HJ, Lee DH, Jung SY, Jung KM, Kim DK. PMID: 19968763.
    View in: PubMed Mentions: 4 Fields:
    Translation:AnimalsCells
  46. Hypoxia-induced neuronal apoptosis is mediated by de novo synthesis of ceramide through activation of serine palmitoyltransferase. Cell Signal. 2010 Apr; 22(4):610-8. Kang MS, Ahn KH, Kim SK, Jeon HJ, Ji JE, Choi JM, Jung KM, Jung SY, Kim DK. PMID: 19932170.
    View in: PubMed Mentions: 21 Fields:
    Translation:HumansCells
  47. Discovery of potent and reversible monoacylglycerol lipase inhibitors. Chem Biol. 2009 Oct 30; 16(10):1045-52. King AR, Dotsey EY, Lodola A, Jung KM, Ghomian A, Qiu Y, Fu J, Mor M, Piomelli D. PMID: 19875078; PMCID: PMC3034734.
    View in: PubMed Mentions: 42 Fields:
    Translation:HumansAnimalsCells
  48. A key role for diacylglycerol lipase-alpha in metabotropic glutamate receptor-dependent endocannabinoid mobilization. Mol Pharmacol. 2007 Sep; 72(3):612-21. Jung KM, Astarita G, Zhu C, Wallace M, Mackie K, Piomelli D. PMID: 17584991.
    View in: PubMed Mentions: 106 Fields:
    Translation:HumansAnimalsCells
  49. Molecular composition of the endocannabinoid system at glutamatergic synapses. J Neurosci. 2006 May 24; 26(21):5628-37. Katona I, Urbán GM, Wallace M, Ledent C, Jung KM, Piomelli D, Mackie K, Freund TF. PMID: 16723519; PMCID: PMC1698282.
    View in: PubMed Mentions: 261 Fields:
    Translation:AnimalsCells
  50. Methylmercury-induced toxicity is mediated by enhanced intracellular calcium through activation of phosphatidylcholine-specific phospholipase C. Toxicol Appl Pharmacol. 2006 Oct 15; 216(2):206-15. Kang MS, Jeong JY, Seo JH, Jeon HJ, Jung KM, Chin MR, Moon CK, Bonventre JV, Jung SY, Kim DK. PMID: 16854443.
    View in: PubMed Mentions: 6 Fields:
    Translation:HumansAnimalsCells
  51. Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors. Mol Pharmacol. 2005 Nov; 68(5):1196-202. Jung KM, Mangieri R, Stapleton C, Kim J, Fegley D, Wallace M, Mackie K, Piomelli D. PMID: 16051747.
    View in: PubMed Mentions: 92 Fields:
    Translation:AnimalsCells
  52. Notch oncoproteins depend on gamma-secretase/presenilin activity for processing and function. J Biol Chem. 2004 Jul 16; 279(29):30771-80. Das I, Craig C, Funahashi Y, Jung KM, Kim TW, Byers R, Weng AP, Kutok JL, Aster JC, Kitajewski J. PMID: 15123653.
    View in: PubMed Mentions: 35 Fields:
    Translation:HumansAnimalsCells
  53. Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor. J Biol Chem. 2003 Oct 24; 278(43):42161-9. Jung KM, Tan S, Landman N, Petrova K, Murray S, Lewis R, Kim PK, Kim DS, Ryu SH, Chao MV, Kim TW. PMID: 12913006.
    View in: PubMed Mentions: 77 Fields:
    Translation:HumansAnimalsCells
  54. Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4. J Biol Chem. 2002 Feb 22; 277(8):6318-23. Lee HJ, Jung KM, Huang YZ, Bennett LB, Lee JS, Mei L, Kim TW. PMID: 11741961.
    View in: PubMed Mentions: 101 Fields:
    Translation:HumansCells

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