Lan Huang • UCI Profiles (original) (raw)

1. CSN5i-3 is an orthosteric molecular glue inhibitor of COP9 signalosome. Nature. 2026 Feb 11. Shi H, Wang X, Yu C, Mao H, Jiao F, Braitbard M, Shor B, Zhang Z, Hinds TR, Cao S, Fan E, Schneidman-Duhovny D, Huang L, Zheng N. PMID: 41673158.
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2. Cysteine-enabled cleavability to advance cross-linking mass spectrometry for global analysis of endogenous protein-protein interactions. Nat Commun. 2025 Dec 12; 16(1):11093. Jiao F, Braitbard M, Yu C, Shor B, Wulff BE, Schneidman-Duhovny D, Huang L. PMID: 41387687; PMCID: PMC12701074.
   View in: PubMed Mentions: Fields:
   Translation:HumansCells
3. LENG8 mediates RNA nuclear retention and degradation in eukaryotes. bioRxiv. 2025 Aug 16. Tian L, Liu L, Yoon Y, Soles LV, Valdez M, Jeong J, Yu C, Huang L, Shi Y. PMID: 40832163; PMCID: PMC12363940.
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4. Trioxane-based MS-cleavable cross-linking mass spectrometry for profiling multimeric interactions of cellular networks. Nat Commun. 2025 Jul 01; 16(1):5585. Yu C, Novitsky E, Balasubramani SG, Wang X, Shen X, Yang Q, Rychnovsky S, Echeverria I, Huang L. PMID: 40593561; PMCID: PMC12215968.
   View in: PubMed Mentions: Fields:
   Translation:HumansAnimals
5. NEMF-mediated CAT tailing facilitates translocation-associated quality control. J Cell Biol. 2025 Jun 02; 224(6). Ennis A, Wang L, Xu Y, Saidi L, Wang X, Yu C, Yun S, Huang L, Ye Y. PMID: 40257401; PMCID: PMC12010919.
   View in: PubMed Mentions: Fields:
   Translation:HumansAnimalsCells
6. Mass Spectrometry-Based Proteomics Technologies to Define Endogenous Protein-Protein Interactions and Their Applications to Cancer and Viral Infectious Diseases. Mass Spectrom Rev. 2025 Feb 09. Yu C, Adavikolanu R, Kaake RM, Huang L. PMID: 39924651; PMCID: PMC12334737.
   View in: PubMed Mentions: 2 Fields:
7. RBBP6 anchors pre-mRNA 3' end processing to nuclear speckles for efficient gene expression. Mol Cell. 2025 Feb 06; 85(3):555-570.e8. Yoon Y, Bournique E, Soles LV, Yin H, Chu HF, Yin C, Zhuang Y, Liu X, Liu L, Jeong J, Yu C, Valdez M, Tian L, Huang L, Shi X, Seelig G, Ding F, Tong L, Buisson R, Shi Y. PMID: 39798570; PMCID: PMC11805622.
   View in: PubMed Mentions: 3 Fields:
   Translation:HumansCells
8. Proximity labeling expansion microscopy (PL-ExM) evaluates interactome labeling techniques. J Mater Chem B. 2024 Aug 28; 12(34):8335-8348. Park S, Wang X, Mo Y, Zhang S, Li X, Fong KC, Yu C, Tran AA, Scipioni L, Dai Z, Huang X, Huang L, Shi X. PMID: 39105364; PMCID: PMC11426358.
   View in: PubMed Mentions: 1 Fields:
   Translation:Humans
9. Huntingtin contains an ubiquitin-binding domain and regulates lysosomal targeting of mitochondrial and RNA-binding proteins. Proc Natl Acad Sci U S A. 2024 Aug 06; 121(32):e2319091121. Fote GM, Eapen VV, Lim RG, Yu C, Salazar L, McClure NR, McKnight J, Nguyen TB, Heath MC, Lau AL, Villamil MA, Miramontes R, Kratter IH, Finkbeiner S, Reidling JC, Paulo JA, Kaiser P, Huang L, Housman DE, Thompson LM, Steffan JS. PMID: 39074279; PMCID: PMC11317567.
   View in: PubMed Mentions: 5 Fields:
   Translation:HumansAnimalsCells
10. Cadmium binding by the F-box domain induces p97-mediated SCF complex disassembly to activate stress response programs. Nat Commun. 2024 May 08; 15(1):3894. Lauinger L, Andronicos A, Flick K, Yu C, Durairaj G, Huang L, Kaiser P. PMID: 38719837; PMCID: PMC11079001.
    View in: PubMed Mentions: 5 Fields:
    Translation:HumansAnimalsCells
11. Mechanism of autocatalytic activation during proteasome assembly. Nat Struct Mol Biol. 2024 Aug; 31(8):1167-1175. Velez B, Walsh RM, Rawson S, Razi A, Adams L, Perez EF, Jiao F, Blickling M, Rajakumar T, Fung D, Huang L, Hanna J. PMID: 38600323; PMCID: PMC11705615.
    View in: PubMed Mentions: 6 Fields:
    Translation:AnimalsCells
12. Mono-UFMylation promotes misfolding-associated secretion of α-synuclein. Sci Adv. 2024 03 15; 10(11):eadk2542. Wang L, Xu Y, Fukushige T, Saidi L, Wang X, Yu C, Lee JG, Krause M, Huang L, Ye Y. PMID: 38489364; PMCID: PMC10942102.
    View in: PubMed Mentions: 6 Fields:
    Translation:HumansAnimalsCells
13. DSBSO-Based XL-MS Analysis of Breast Cancer PDX Tissues to Delineate Protein Interaction Network in Clinical Samples. J Proteome Res. 2024 08 02; 23(8):3269-3279. Jiao F, Yu C, Wheat A, Chen L, Lih TM, Zhang H, Huang L. PMID: 38334954; PMCID: PMC11296914.
    View in: PubMed Mentions: 6 Fields:
    Translation:HumansAnimals
14. Proximity Labeling Expansion Microscopy (PL-ExM) resolves structure of the interactome. bioRxiv. 2023 Nov 13. Park S, Wang X, Li X, Huang X, Fong KC, Yu C, Tran AA, Scipioni L, Dai Z, Huang L, Shi X. PMID: 38014020; PMCID: PMC10680661.
    View in: PubMed Mentions: 1
15. The Hippo pathway noncanonically drives autophagy and cell survival in response to energy stress. Mol Cell. 2023 09 07; 83(17):3155-3170.e8. Seo G, Yu C, Han H, Xing L, Kattan RE, An J, Kizhedathu A, Yang B, Luo A, Buckle AL, Tifrea D, Edwards R, Huang L, Ju HQ, Wang W. PMID: 37595580; PMCID: PMC10568779.
    View in: PubMed Mentions: 10 Fields:
    Translation:AnimalsCells
16. Mapping Pregnancy-dependent Sulfhydrome Unfolds Diverse Functions of Protein Sulfhydration in Human Uterine Artery. Endocrinology. 2023 08 01; 164(9). Bai J, Jiao F, Salmeron AG, Xu S, Xian M, Huang L, Chen DB. PMID: 37439247; PMCID: PMC10413431.
    View in: PubMed Mentions: 7 Fields:
    Translation:Humans
17. New advances in cross-linking mass spectrometry toward structural systems biology. Curr Opin Chem Biol. 2023 10; 76:102357. Yu C, Huang L. PMID: 37406423; PMCID: PMC11091472.
    View in: PubMed Mentions: 18 Fields:
    Translation:Humans
18. Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood. Cell Metab. 2023 07 11; 35(7):1227-1241.e7. Lin L, Jung KM, Lee HL, Le J, Colleluori G, Wood C, Palese F, Squire E, Ramirez J, Su S, Torrens A, Fotio Y, Tang L, Yu C, Yang Q, Huang L, DiPatrizio N, Jang C, Cinti S, Piomelli D. PMID: 37267956; PMCID: PMC10524841.
    View in: PubMed Mentions: 14 Fields:
    Translation:Animals
19. Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry. Anal Chem. 2023 01 31; 95(4):2532-2539. Jiao F, Salituro LJ, Yu C, Gutierrez CB, Rychnovsky SD, Huang L. PMID: 36652389; PMCID: PMC10284117.
    View in: PubMed Mentions: 10 Fields:
    Translation:HumansCells
20. Discovery of compounds that reactivate p53 mutants in vitro and in vivo. Cell Chem Biol. 2022 09 15; 29(9):1381-1395.e13. Durairaj G, Demir Ö, Lim B, Baronio R, Tifrea D, Hall LV, DeForest JC, Lauinger L, Jebril Fallatah MM, Yu C, Bae H, Lin DW, Kim JK, Salehi F, Jang C, Qiao F, Lathrop RH, Huang L, Edwards R, Rychnovsky S, Amaro RE, Kaiser P. PMID: 35948006; PMCID: PMC9481737.
    View in: PubMed Mentions: 12 Fields:
    Translation:HumansCells
21. Point-of-care COPD diagnostics: biomarkers, sampling, paper-based analytical devices, and perspectives. Analyst. 2022 Mar 28; 147(7):1273-1293. He G, Dong T, Yang Z, Branstad A, Huang L, Jiang Z. PMID: 35113085.
    View in: PubMed Mentions: 6 Fields:
    Translation:Humans
22. Structure and conformational dynamics of Clostridioides difficile toxin A. Life Sci Alliance. 2022 06; 5(6). Chen B, Basak S, Chen P, Zhang C, Perry K, Tian S, Yu C, Dong M, Huang L, Bowen ME, Jin R. PMID: 35292538; PMCID: PMC8924006.
    View in: PubMed Mentions: 11 Fields:
    Translation:Cells
23. Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis. Anal Chem. 2022 03 15; 94(10):4236-4242. Jiao F, Yu C, Wheat A, Wang X, Rychnovsky SD, Huang L. PMID: 35235311; PMCID: PMC9056026.
    View in: PubMed Mentions: 19 Fields:
    Translation:HumansCells
24. Developing a Targeted Quantitative Strategy for Sulfoxide-Containing MS-Cleavable Cross-Linked Peptides to Probe Conformational Dynamics of Protein Complexes. Anal Chem. 2022 03 15; 94(10):4390-4398. Yu C, Wang X, Huang L. PMID: 35193351; PMCID: PMC9000990.
    View in: PubMed Mentions: 7 Fields:
    Translation:Humans
25. The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1. Nat Cell Biol. 2022 01; 24(1):74-87. Han H, Nakaoka HJ, Hofmann L, Zhou JJ, Yu C, Zeng L, Nan J, Seo G, Vargas RE, Yang B, Qi R, Bardwell L, Fishman DA, Cho KWY, Huang L, Luo R, Warrior R, Wang W. PMID: 35027733; PMCID: PMC9022944.
    View in: PubMed Mentions: 22 Fields:
    Translation:HumansCells
26. The Ubiquitin Interacting Motif-Like Domain of Met4 Selectively Binds K48 Polyubiquitin Chains. Mol Cell Proteomics. 2022 01; 21(1):100175. Villamil M, Xiao W, Yu C, Huang L, Xu P, Kaiser P. PMID: 34763062; PMCID: PMC8693465.
    View in: PubMed Mentions: 3 Fields:
    Translation:AnimalsCells
27. Developing a Bimolecular Affinity Purification Strategy to Isolate 26S Proteasome Holocomplexes for Complex-Centric Proteomic Analysis. Anal Chem. 2021 10 05; 93(39):13407-13413. Yu C, Wang X, Li W, Liu Y, Huang L. PMID: 34550675; PMCID: PMC8999942.
    View in: PubMed Mentions: 3 Fields:
28. Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1. JCI Insight. 2021 09 08; 6(17). Cao Y, Tang L, Du K, Paraiso K, Sun Q, Liu Z, Ye X, Fang Y, Yuan F, Chen H, Chen Y, Wang X, Yu C, Blitz IL, Wang PH, Huang L, Cheng H, Lu X, Cho KW, Seldin M, Fang Z, Yang Q. PMID: 34314389; PMCID: PMC8492328.
    View in: PubMed Mentions: 7 Fields:
    Translation:AnimalsCells
29. Protein interaction landscapes revealed by advanced in vivo cross-linking-mass spectrometry. Proc Natl Acad Sci U S A. 2021 08 10; 118(32). Wheat A, Yu C, Wang X, Burke AM, Chemmama IE, Kaake RM, Baker P, Rychnovsky SD, Yang J, Huang L. PMID: 34349018; PMCID: PMC8364181.
    View in: PubMed Mentions: 61 Fields:
    Translation:HumansCells
30. Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection. Nat Commun. 2021 06 18; 12(1):3748. Chen P, Zeng J, Liu Z, Thaker H, Wang S, Tian S, Zhang J, Tao L, Gutierrez CB, Xing L, Gerhard R, Huang L, Dong M, Jin R. PMID: 34145250; PMCID: PMC8213806.
    View in: PubMed Mentions: 45 Fields:
    Translation:AnimalsCells
31. Enabling Photoactivated Cross-Linking Mass Spectrometric Analysis of Protein Complexes by Novel MS-Cleavable Cross-Linkers. Mol Cell Proteomics. 2021; 20:100084. Gutierrez C, Salituro LJ, Yu C, Wang X, DePeter SF, Rychnovsky SD, Huang L. PMID: 33915260; PMCID: PMC8214149.
    View in: PubMed Mentions: 14 Fields:
    Translation:AnimalsCells
32. Quality-Control Mechanism for Telomerase RNA Folding in the Cell. Cell Rep. 2020 12 29; 33(13):108568. Hu X, Kim JK, Yu C, Jun HI, Liu J, Sankaran B, Huang L, Qiao F. PMID: 33378677.
    View in: PubMed Mentions: 12 Fields:
    Translation:AnimalsCells
33. Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes. PLoS Genet. 2020 06; 16(6):e1008881. Alkafeef SS, Lane S, Yu C, Zhou T, Solis NV, Filler SG, Huang L, Liu H. PMID: 32525871; PMCID: PMC7319344.
    View in: PubMed Mentions: 13 Fields:
    Translation:HumansAnimals
34. Structural dynamics of the human COP9 signalosome revealed by cross-linking mass spectrometry and integrative modeling. Proc Natl Acad Sci U S A. 2020 02 25; 117(8):4088-4098. Gutierrez C, Chemmama IE, Mao H, Yu C, Echeverria I, Block SA, Rychnovsky SD, Zheng N, Sali A, Huang L. PMID: 32034103; PMCID: PMC7049115.
    View in: PubMed Mentions: 42 Fields:
    Translation:HumansCells
35. Structure of the full-length Clostridium difficile toxin B. Nat Struct Mol Biol. 2019 08; 26(8):712-719. Chen P, Lam KH, Liu Z, Mindlin FA, Chen B, Gutierrez CB, Huang L, Zhang Y, Hamza T, Feng H, Matsui T, Bowen ME, Perry K, Jin R. PMID: 31308519; PMCID: PMC6684407.
    View in: PubMed Mentions: 55 Fields:
    Translation:Cells
36. Human red and green cone opsins are O-glycosylated at an N-terminal Ser/Thr-rich domain conserved in vertebrates. J Biol Chem. 2019 05 17; 294(20):8123-8133. Salom D, Jin H, Gerken TA, Yu C, Huang L, Palczewski K. PMID: 30948514; PMCID: PMC6527158.
    View in: PubMed Mentions: 6 Fields:
    Translation:HumansAnimalsCells
37. Probing H2O2-mediated Structural Dynamics of the Human 26S Proteasome Using Quantitative Cross-linking Mass Spectrometry (QXL-MS). Mol Cell Proteomics. 2019 05; 18(5):954-967. Yu C, Wang X, Huszagh AS, Viner R, Novitsky E, Rychnovsky SD, Huang L. PMID: 30723094; PMCID: PMC6495261.
    View in: PubMed Mentions: 8 Fields:
    Translation:Humans
38. Development of a Novel Sulfoxide-Containing MS-Cleavable Homobifunctional Cysteine-Reactive Cross-Linker for Studying Protein-Protein Interactions. Anal Chem. 2018 06 19; 90(12):7600-7607. Gutierrez CB, Block SA, Yu C, Soohoo SM, Huszagh AS, Rychnovsky SD, Huang L. PMID: 29792801; PMCID: PMC6037416.
    View in: PubMed Mentions: 22 Fields:
    Translation:AnimalsCells
39. Wor1 establishes opaque cell fate through inhibition of the general co-repressor Tup1 in Candida albicans. PLoS Genet. 2018 01; 14(1):e1007176. Alkafeef SS, Yu C, Huang L, Liu H. PMID: 29337983; PMCID: PMC5786334.
    View in: PubMed Mentions: 18 Fields:
    Translation:AnimalsCells
40. Dissecting Dynamic and Heterogeneous Proteasome Complexes Using In Vivo Cross-Linking-Assisted Affinity Purification and Mass Spectrometry. Methods Mol Biol. 2018; 1844:401-410. Wang X, Huang L. PMID: 30242723; PMCID: PMC6944201.
    View in: PubMed Mentions: 1 Fields:
    Translation:HumansCells
41. Cross-Linking Mass Spectrometry: An Emerging Technology for Interactomics and Structural Biology. Anal Chem. 2018 01 02; 90(1):144-165. Yu C, Huang L. PMID: 29160693; PMCID: PMC6022837.
    View in: PubMed Mentions: 160 Fields:
42. Structural Basis for Shelterin Bridge Assembly. Mol Cell. 2017 Nov 16; 68(4):698-714.e5. Kim JK, Liu J, Hu X, Yu C, Roskamp K, Sankaran B, Huang L, Komives EA, Qiao F. PMID: 29149597; PMCID: PMC5698806.
    View in: PubMed Mentions: 17 Fields:
    Translation:HumansAnimalsCells
43. The proteasome-interacting Ecm29 protein disassembles the 26S proteasome in response to oxidative stress. J Biol Chem. 2017 09 29; 292(39):16310-16320. Wang X, Chemmama IE, Yu C, Huszagh A, Xu Y, Viner R, Block SA, Cimermancic P, Rychnovsky SD, Ye Y, Sali A, Huang L. PMID: 28821611; PMCID: PMC5625060.
    View in: PubMed Mentions: 56 Fields:
    Translation:HumansCells
44. Nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) is regulated by O-GlcNAc transferase. Free Radic Biol Med. 2017 09; 110:196-205. Han JW, Valdez JL, Ho DV, Lee CS, Kim HM, Wang X, Huang L, Chan JY. PMID: 28625484.
    View in: PubMed Mentions: 22 Fields:
    Translation:HumansCells
45. Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome. Mol Cell Proteomics. 2017 05; 16(5):840-854. Wang X, Cimermancic P, Yu C, Schweitzer A, Chopra N, Engel JL, Greenberg C, Huszagh AS, Beck F, Sakata E, Yang Y, Novitsky EJ, Leitner A, Nanni P, Kahraman A, Guo X, Dixon JE, Rychnovsky SD, Aebersold R, Baumeister W, Sali A, Huang L. PMID: 28292943; PMCID: PMC5417825.
    View in: PubMed Mentions: 57 Fields:
    Translation:HumansCells
46. Developing a Multiplexed Quantitative Cross-Linking Mass Spectrometry Platform for Comparative Structural Analysis of Protein Complexes. Anal Chem. 2016 10 18; 88(20):10301-10308. Yu C, Huszagh A, Viner R, Novitsky EJ, Rychnovsky SD, Huang L. PMID: 27626298; PMCID: PMC5361889.
    View in: PubMed Mentions: 37 Fields:
    Translation:Cells
47. Developing an Acidic Residue Reactive and Sulfoxide-Containing MS-Cleavable Homobifunctional Cross-Linker for Probing Protein-Protein Interactions. Anal Chem. 2016 08 16; 88(16):8315-22. Gutierrez CB, Yu C, Novitsky EJ, Huszagh AS, Rychnovsky SD, Huang L. PMID: 27417384; PMCID: PMC4989248.
    View in: PubMed Mentions: 34 Fields:
    Translation:AnimalsCells
48. Characterization of Dynamic UbR-Proteasome Subcomplexes by In vivo Cross-linking (X) Assisted Bimolecular Tandem Affinity Purification (XBAP) and Label-free Quantitation. Mol Cell Proteomics. 2016 07; 15(7):2279-92. Yu C, Yang Y, Wang X, Guan S, Fang L, Liu F, Walters KJ, Kaiser P, Huang L. PMID: 27114451; PMCID: PMC4937504.
    View in: PubMed Mentions: 29 Fields:
    Translation:HumansCells
49. Quantitative Proteomics Analysis of VEGF-Responsive Endothelial Protein S-Nitrosylation Using Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and LC-MS/MS. Biol Reprod. 2016 05; 94(5):114. Zhang HH, Lechuga TJ, Chen Y, Yang Y, Huang L, Chen DB. PMID: 27075618; PMCID: PMC4939742.
    View in: PubMed Mentions: 6 Fields:
    Translation:AnimalsCells
50. Gln40 deamidation blocks structural reconfiguration and activation of SCF ubiquitin ligase complex by Nedd8. Nat Commun. 2015 Dec 03; 6:10053. Yu C, Mao H, Novitsky EJ, Tang X, Rychnovsky SD, Zheng N, Huang L. PMID: 26632597; PMCID: PMC4686759.
    View in: PubMed Mentions: 25 Fields:
    Translation:HumansCells
51. Design of CID-cleavable protein cross-linkers: identical mass modifications for simpler sequence analysis. Org Biomol Chem. 2015 Oct 14; 13(38):9793-807. Kandur WV, Kao A, Vellucci D, Huang L, Rychnovsky SD. PMID: 26269432; PMCID: PMC4581996.
    View in: PubMed Mentions: 8 Fields:
    Translation:HumansCells
52. Activation of m1 muscarinic acetylcholine receptor induces surface transport of KCNQ channels through a CRMP-2-mediated pathway. J Cell Sci. 2015 Nov 15; 128(22):4235-45. Jiang L, Kosenko A, Yu C, Huang L, Li X, Hoshi N. PMID: 26446259; PMCID: PMC4712786.
    View in: PubMed Mentions: 6 Fields:
    Translation:HumansAnimalsCells
53. Ty3 Retrotransposon Hijacks Mating Yeast RNA Processing Bodies to Infect New Genomes. PLoS Genet. 2015; 11(9):e1005528. Bilanchone V, Clemens K, Kaake R, Dawson AR, Matheos D, Nagashima K, Sitlani P, Patterson K, Chang I, Huang L, Sandmeyer S. PMID: 26421679; PMCID: PMC4589538.
    View in: PubMed Mentions: 19 Fields:
    Translation:AnimalsCells
54. Dissecting Fission Yeast Shelterin Interactions via MICro-MS Links Disruption of Shelterin Bridge to Tumorigenesis. Cell Rep. 2015 Sep 29; 12(12):2169-80. Liu J, Yu C, Hu X, Kim JK, Bierma JC, Jun HI, Rychnovsky SD, Huang L, Qiao F. PMID: 26365187; PMCID: PMC4591219.
    View in: PubMed Mentions: 12 Fields:
    Translation:HumansAnimalsCells
55. Synthesis of two new enrichable and MS-cleavable cross-linkers to define protein-protein interactions by mass spectrometry. Org Biomol Chem. 2015 May 07; 13(17):5030-7. Burke AM, Kandur W, Novitsky EJ, Kaake RM, Yu C, Kao A, Vellucci D, Huang L, Rychnovsky SD. PMID: 25823605; PMCID: PMC4420144.
    View in: PubMed Mentions: 25 Fields:
    Translation:Cells
56. S-nitrosylation of Cofilin-1 Serves as a Novel Pathway for VEGF-Stimulated Endothelial Cell Migration. J Cell Physiol. 2015 Feb; 230(2):406-17. Zhang HH, Wang W, Feng L, Yang Y, Zheng J, Huang L, Chen DB. PMID: 25056928; PMCID: PMC8906234.
    View in: PubMed Mentions: 22 Fields:
    Translation:HumansCells
57. A new in vivo cross-linking mass spectrometry platform to define protein-protein interactions in living cells. Mol Cell Proteomics. 2014 Dec; 13(12):3533-43. Kaake RM, Wang X, Burke A, Yu C, Kandur W, Yang Y, Novtisky EJ, Second T, Duan J, Kao A, Guan S, Vellucci D, Rychnovsky SD, Huang L. PMID: 25253489; PMCID: PMC4256503.
    View in: PubMed Mentions: 101 Fields:
    Translation:HumansAnimalsCells
58. Endogenous NO upon estradiol-17β stimulation and NO donor differentially regulate mitochondrial S-nitrosylation in endothelial cells. Endocrinology. 2014 Aug; 155(8):3005-16. Satohisa S, Zhang HH, Feng L, Yang YY, Huang L, Chen DB. PMID: 24877627; PMCID: PMC4098011.
    View in: PubMed Mentions: 8 Fields:
    Translation:HumansCells
59. Characterizing the dynamics of proteasome complexes by proteomics approaches. Antioxid Redox Signal. 2014 Dec 10; 21(17):2444-56. Kaake RM, Kao A, Yu C, Huang L. PMID: 24423446; PMCID: PMC4241863.
    View in: PubMed Mentions: 6 Fields:
60. Developing new isotope-coded mass spectrometry-cleavable cross-linkers for elucidating protein structures. Anal Chem. 2014 Feb 18; 86(4):2099-106. Yu C, Kandur W, Kao A, Rychnovsky S, Huang L. PMID: 24471733; PMCID: PMC3985771.
    View in: PubMed Mentions: 23 Fields:
    Translation:AnimalsCells
61. Defining dynamic protein interactions using SILAC-based quantitative mass spectrometry. Methods Mol Biol. 2014; 1188:191-205. Wang X, Huang L. PMID: 25059613; PMCID: PMC4444047.
    View in: PubMed Mentions: 4 Fields:
    Translation:HumansCells
62. Combining docking site and phosphosite predictions to find new substrates: identification of smoothelin-like-2 (SMTNL2) as a c-Jun N-terminal kinase (JNK) substrate. Cell Signal. 2013 Dec; 25(12):2518-29. Gordon EA, Whisenant TC, Zeller M, Kaake RM, Gordon WM, Krotee P, Patel V, Huang L, Baldi P, Bardwell L. PMID: 23981301; PMCID: PMC4132694.
    View in: PubMed Mentions: 20 Fields:
    Translation:HumansAnimalsCells
63. A novel role for lipid droplets in the organismal antibacterial response. Elife. 2012 Nov 13; 1:e00003. Anand P, Cermelli S, Li Z, Kassan A, Bosch M, Sigua R, Huang L, Ouellette AJ, Pol A, Welte MA, Gross SP. PMID: 23150794; PMCID: PMC3491588.
    View in: PubMed Mentions: 69 Fields:
    Translation:AnimalsCells
64. Signal-induced disassembly of the SCF ubiquitin ligase complex by Cdc48/p97. Mol Cell. 2012 Oct 26; 48(2):288-97. Yen JL, Flick K, Papagiannis CV, Mathur R, Tyrrell A, Ouni I, Kaake RM, Huang L, Kaiser P. PMID: 23000173; PMCID: PMC3483439.
    View in: PubMed Mentions: 26 Fields:
    Translation:AnimalsCells
65. Mapping the structural topology of the yeast 19S proteasomal regulatory particle using chemical cross-linking and probabilistic modeling. Mol Cell Proteomics. 2012 Dec; 11(12):1566-77. Kao A, Randall A, Yang Y, Patel VR, Kandur W, Guan S, Rychnovsky SD, Baldi P, Huang L. PMID: 22550050; PMCID: PMC3518129.
    View in: PubMed Mentions: 30 Fields:
    Translation:AnimalsCells
66. Mapping the protein interaction network of the human COP9 signalosome complex using a label-free QTAX strategy. Mol Cell Proteomics. 2012 May; 11(5):138-47. Fang L, Kaake RM, Patel VR, Yang Y, Baldi P, Huang L. PMID: 22474085; PMCID: PMC3418852.
    View in: PubMed Mentions: 30 Fields:
    Translation:HumansCells
67. Casein kinase 2 reverses tail-independent inactivation of kinesin-1. Nat Commun. 2012 Mar 27; 3:754. Xu J, Reddy BJ, Anand P, Shu Z, Cermelli S, Mattson MK, Tripathy SK, Hoss MT, James NS, King SJ, Huang L, Bardwell L, Gross SP. PMID: 22453827; PMCID: PMC3574636.
    View in: PubMed Mentions: 22 Fields:
    Translation:AnimalsCells
68. Oxidative stress-mediated regulation of proteasome complexes. Mol Cell Proteomics. 2011 May; 10(5):R110.006924. Aiken CT, Kaake RM, Wang X, Huang L. PMID: 21543789; PMCID: PMC3098605.
    View in: PubMed Mentions: 177 Fields:
    Translation:HumansAnimalsCells
69. IL-25 causes apoptosis of IL-25R-expressing breast cancer cells without toxicity to nonmalignant cells. Sci Transl Med. 2011 Apr 13; 3(78):78ra31. Furuta S, Jeng YM, Zhou L, Huang L, Kuhn I, Bissell MJ, Lee WH. PMID: 21490275; PMCID: PMC3199022.
    View in: PubMed Mentions: 66 Fields:
    Translation:HumansCells
70. Pentatricopeptide repeat proteins stimulate mRNA adenylation/uridylation to activate mitochondrial translation in trypanosomes. Mol Cell. 2011 Apr 08; 42(1):106-17. Aphasizheva I, Maslov D, Wang X, Huang L, Aphasizhev R. PMID: 21474072; PMCID: PMC3073060.
    View in: PubMed Mentions: 71 Fields:
    Translation:AnimalsCells
71. Quantitative profiling of in vivo-assembled RNA-protein complexes using a novel integrated proteomic approach. Mol Cell Proteomics. 2011 Apr; 10(4):M110.007385. Tsai BP, Wang X, Huang L, Waterman ML. PMID: 21285413; PMCID: PMC3069349.
    View in: PubMed Mentions: 76 Fields:
    Translation:HumansCells
72. Regulation of the 26S proteasome complex during oxidative stress. Sci Signal. 2010 Dec 07; 3(151):ra88. Wang X, Yen J, Kaiser P, Huang L. PMID: 21139140; PMCID: PMC3140957.
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    Translation:HumansAnimalsCells
73. Computational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factors. PLoS Comput Biol. 2010 Aug 26; 6(8). Whisenant TC, Ho DT, Benz RW, Rogers JS, Kaake RM, Gordon EA, Huang L, Baldi P, Bardwell L. PMID: 20865152; PMCID: PMC2928751.
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74. Development of a novel cross-linking strategy for fast and accurate identification of cross-linked peptides of protein complexes. Mol Cell Proteomics. 2011 Jan; 10(1):M110.002212. Kao A, Chiu CL, Vellucci D, Yang Y, Patel VR, Guan S, Randall A, Baldi P, Rychnovsky SD, Huang L. PMID: 20736410; PMCID: PMC3013449.
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75. Profiling of protein interaction networks of protein complexes using affinity purification and quantitative mass spectrometry. Mol Cell Proteomics. 2010 Aug; 9(8):1650-65. Kaake RM, Wang X, Huang L. PMID: 20445003; PMCID: PMC2938061.
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76. Selective enrichment and identification of azide-tagged cross-linked peptides using chemical ligation and mass spectrometry. J Am Soc Mass Spectrom. 2010 Aug; 21(8):1432-45. Vellucci D, Kao A, Kaake RM, Rychnovsky SD, Huang L. PMID: 20472459; PMCID: PMC3119349.
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77. Characterization of cell cycle specific protein interaction networks of the yeast 26S proteasome complex by the QTAX strategy. J Proteome Res. 2010 Apr 05; 9(4):2016-29. Kaake RM, Milenkovic T, Przulj N, Kaiser P, Huang L. PMID: 20170199; PMCID: PMC3140958.
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78. Mechanism of U insertion RNA editing in trypanosome mitochondria: the bimodal TUTase activity of the core complex. J Mol Biol. 2010 Jun 25; 399(5):680-95. Ringpis GE, Aphasizheva I, Wang X, Huang L, Lathrop RH, Hatfield GW, Aphasizhev R. PMID: 20362585; PMCID: PMC2885523.
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79. IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. J Cell Biol. 2009 Dec 28; 187(7):1083-99. Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, Zeitlin SO, Finkbeiner S, Green KN, LaFerla FM, Bates G, Huang L, Patterson PH, Lo DC, Cuervo AM, Marsh JL, Steffan JS. PMID: 20026656; PMCID: PMC2806289.
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80. Phosphorylation of threonine 3: implications for Huntingtin aggregation and neurotoxicity. J Biol Chem. 2009 Oct 23; 284(43):29427-36. Aiken CT, Steffan JS, Guerrero CM, Khashwji H, Lukacsovich T, Simmons D, Purcell JM, Menhaji K, Zhu YZ, Green K, Laferla F, Huang L, Thompson LM, Marsh JL. PMID: 19710014; PMCID: PMC2785575.
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81. GM130-dependent control of Cdc42 activity at the Golgi regulates centrosome organization. Mol Biol Cell. 2009 Feb; 20(4):1192-200. Kodani A, Kristensen I, Huang L, Sütterlin C. PMID: 19109421; PMCID: PMC2642749.
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82. Guide RNA-binding complex from mitochondria of trypanosomatids. Mol Cell. 2008 Oct 24; 32(2):198-209. Weng J, Aphasizheva I, Etheridge RD, Huang L, Wang X, Falick AM, Aphasizhev R. PMID: 18951088; PMCID: PMC2645705.
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83. Characterization of the human COP9 signalosome complex using affinity purification and mass spectrometry. J Proteome Res. 2008 Nov; 7(11):4914-25. Fang L, Wang X, Yamoah K, Chen PL, Pan ZQ, Huang L. PMID: 18850735; PMCID: PMC2676908.
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84. Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. J Proteome Res. 2008 Oct; 7(10):4566-76. Meierhofer D, Wang X, Huang L, Kaiser P. PMID: 18781797; PMCID: PMC2758155.
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85. Characterization of the proteasome interaction network using a QTAX-based tag-team strategy and protein interaction network analysis. Proc Natl Acad Sci U S A. 2008 Sep 09; 105(36):13333-8. Guerrero C, Milenkovic T, Przulj N, Kaiser P, Huang L. PMID: 18757749; PMCID: PMC2533190.
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86. A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins. J Proteome Res. 2008 Mar; 7(3):1274-87. Jones J, Wu K, Yang Y, Guerrero C, Nillegoda N, Pan ZQ, Huang L. PMID: 18247557; PMCID: PMC2676899.
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87. Tandem affinity purification combined with mass spectrometry to identify components of protein complexes. Methods Mol Biol. 2008; 439:309-26. Kaiser P, Meierhofer D, Wang X, Huang L. PMID: 18370112; PMCID: PMC3228642.
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88. Identifying dynamic interactors of protein complexes by quantitative mass spectrometry. Mol Cell Proteomics. 2008 Jan; 7(1):46-57. Wang X, Huang L. PMID: 17934176.
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89. Proteomics of proteasome complexes and ubiquitinated proteins. Expert Rev Proteomics. 2007 Oct; 4(5):649-65. Wang X, Guerrero C, Kaiser P, Huang L. PMID: 17941820.
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90. Mass spectrometric characterization of the affinity-purified human 26S proteasome complex. Biochemistry. 2007 Mar 20; 46(11):3553-65. Wang X, Chen CF, Baker PR, Chen PL, Kaiser P, Huang L. PMID: 17323924.
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91. Modulation of DRAK2 autophosphorylation by antigen receptor signaling in primary lymphocytes. J Biol Chem. 2007 Feb 16; 282(7):4573-4584. Friedrich ML, Cui M, Hernandez JB, Weist BM, Andersen HM, Zhang X, Huang L, Walsh CM. PMID: 17182616.
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92. HB tag modules for PCR-based gene tagging and tandem affinity purification in Saccharomyces cerevisiae. Yeast. 2006 Jun; 23(8):623-32. Tagwerker C, Zhang H, Wang X, Larsen LS, Lathrop RH, Hatfield GW, Auer B, Huang L, Kaiser P. PMID: 16823883.
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93. A tandem affinity tag for two-step purification under fully denaturing conditions: application in ubiquitin profiling and protein complex identification combined with in vivocross-linking. Mol Cell Proteomics. 2006 Apr; 5(4):737-48. Tagwerker C, Flick K, Cui M, Guerrero C, Dou Y, Auer B, Baldi P, Huang L, Kaiser P. PMID: 16432255.
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94. An integrated mass spectrometry-based proteomic approach: quantitative analysis of tandem affinity-purified in vivo cross-linked protein complexes (QTAX) to decipher the 26 S proteasome-interacting network. Mol Cell Proteomics. 2006 Feb; 5(2):366-78. Guerrero C, Tagwerker C, Kaiser P, Huang L. PMID: 16284124.
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95. Global approaches to understanding ubiquitination. Genome Biol. 2005; 6(10):233. Kaiser P, Huang L. PMID: 16207362; PMCID: PMC1257457.
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96. Comprehensive mass spectrometric analysis of the 20S proteasome complex. Methods Enzymol. 2005; 405:187-236. Huang L, Burlingame AL. PMID: 16413316.
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97. Fus3-regulated Tec1 degradation through SCFCdc4 determines MAPK signaling specificity during mating in yeast. Cell. 2004 Dec 29; 119(7):981-90. Chou S, Huang L, Liu H. PMID: 15620356.
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    Translation:AnimalsCells

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