Roberto Tinoco • UCI Profiles (original) (raw)
- The protein phosphatase 6 subunit SAPS3 modulates lifespan by regulating metabolism. Sci Adv. 2025 Oct 24; 11(43):eadt3879. Yang Y, Kang DE, Fan Q, Hanse EA, Bae H, Barahona RA, Shen X, Ruiz BI, Lee SH, Pasterczyk KR, Babbar N, Waldvogel KG, Tinoco R, Green KN, Yang Q, Jang C, Kong M. PMID: 41134908; PMCID: PMC12551702.
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Translation:AnimalsCells - Toll-like Receptor 4 Contributes to PCOS-like Metabolic and Reproductive Pathogenesis. bioRxiv. 2025 Oct 17. Wiggins K, Del Mundo Z, Angulo JA, Naidu N, Saba A, Garcia C, Nguyen C, Ujagar N, De La Torre JJ, De Robles G, Rivera A, Trinh D, Tinoco R, Kauffman AS, Thackray VG, Agrawal A, Seldin M, Sanchez GP, Nicholas D. PMID: 41279684; PMCID: PMC12632965.
View in: PubMed Mentions: - Spatial and Single-Cell Transcriptomics Reveal Keratinocytes as Key Players in Vulvar Lichen Sclerosus Pathogenesis. J Invest Dermatol. 2026 Mar; 146(3):678-698.e5. Sun P, Kraus CN, Zhao W, Xu J, Suh S, Nguyen Q, Jia Y, Nair A, Oakes M, Tinoco R, Shiu J, Sun B, Elsensohn A, Atwood SX, Nie Q, Dai X. PMID: 40886965; PMCID: PMC12591268.
View in: PubMed Mentions: Fields: - UHRF1 is critical for tumor-promoting inflammation and tumorigenesis in retinoblastoma. bioRxiv. 2025 Mar 07. Gu Y, Suarez-Pizarro M, Chen CC, Wu J, Zocchi L, Suh S, Smith PJ, Cruz S, Tinoco R, Benavente CA. PMID: 40093113; PMCID: PMC11908184.
View in: PubMed Mentions: - Contrasting roles of PSGL-1 and PD-1 in regulating T-cell exhaustion and function during chronic viral infection. J Virol. 2025 03 18; 99(3):e0224224. Viramontes KM, Thone MN, De La Torre J-J, Neubert EN, DeRogatis JM, Garcia C, Henriquez ML, Tinoco R. PMID: 39912665; PMCID: PMC11915808.
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Translation:AnimalsCells - Prion protein modulation of virus-specific T cell differentiation and function during acute viral infection. Immunohorizons. 2025 01 23; 9(1). Viramontes KM, Thone MN, DeRogatis JM, Neubert EN, Henriquez ML, De La Torre JJ, Tinoco R. PMID: 39846843; PMCID: PMC11841969.
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Translation:AnimalsCells - Single-cell and spatial transcriptomics of vulvar lichen sclerosus reveal multi-compartmental alterations in gene expression and signaling cross-talk. bioRxiv. 2024 Aug 17. Sun P, Kraus CN, Zhao W, Xu J, Suh S, Nguyen Q, Jia Y, Nair A, Oakes M, Tinoco R, Shiu J, Sun B, Elsensohn A, Atwood SX, Nie Q, Dai X. PMID: 39211101; PMCID: PMC11361165.
View in: PubMed Mentions: - HMGB2 regulates the differentiation and stemness of exhausted CD8+ T cells during chronic viral infection and cancer. Nat Commun. 2023 09 13; 14(1):5631. Neubert EN, DeRogatis JM, Lewis SA, Viramontes KM, Ortega P, Henriquez ML, Buisson R, Messaoudi I, Tinoco R. PMID: 37704621; PMCID: PMC10499904.
View in: PubMed Mentions: 22 Fields:
Translation:HumansCells - PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion. Cell Rep. 2023 05 30; 42(5):112436. Hope JL, Otero DC, Bae EA, Stairiker CJ, Palete AB, Faso HA, Lin M, Henriquez ML, Roy S, Seo H, Lei X, Wang ES, Chow S, Tinoco R, Daniels GA, Yip K, Campos AR, Yin J, Adams PD, Rao A, Bradley LM. PMID: 37115668; PMCID: PMC10403047.
View in: PubMed Mentions: 17 Fields:
Translation:HumansCells - Cell-Intrinsic CD38 Expression Sustains Exhausted CD8+ T Cells by Regulating Their Survival and Metabolism during Chronic Viral Infection. J Virol. 2023 04 27; 97(4):e0022523. DeRogatis JM, Neubert EN, Viramontes KM, Henriquez ML, Nicholas DA, Tinoco R. PMID: 37039663; PMCID: PMC10134879.
View in: PubMed Mentions: 12 Fields:
Translation:AnimalsCells - PD-1 Immune Checkpoint Blockade and PSGL-1 Inhibition Synergize to Reinvigorate Exhausted T Cells. Front Immunol. 2022; 13:869768. Viramontes KM, Neubert EN, DeRogatis JM, Tinoco R. PMID: 35774790; PMCID: PMC9237324.
View in: PubMed Mentions: 14 Fields:
Translation:HumansCells - Targeting the PSGL-1 Immune Checkpoint Promotes Immunity to PD-1-Resistant Melanoma. Cancer Immunol Res. 2022 05 03; 10(5):612-625. DeRogatis JM, Viramontes KM, Neubert EN, Henriquez ML, Guerrero-Juarez CF, Tinoco R. PMID: 35303066; PMCID: PMC9064985.
View in: PubMed Mentions: 20 Fields:
Translation:HumansAnimalsCells - The cure from within? a review of the microbiome and diet in melanoma. Cancer Metastasis Rev. 2022 06; 41(2):261-280. Kumar P, Brazel D, DeRogatis J, Valerin JBG, Whiteson K, Chow WA, Tinoco R, Moyers JT. PMID: 35474500; PMCID: PMC9042647.
View in: PubMed Mentions: 15 Fields:
Translation:Humans - PSGL-1 Is a T Cell Intrinsic Inhibitor That Regulates Effector and Memory Differentiation and Responses During Viral Infection. Front Immunol. 2021; 12:677824. Tinoco R, Neubert EN, Stairiker CJ, Henriquez ML, Bradley LM. PMID: 34326837; PMCID: PMC8314012.
View in: PubMed Mentions: 16 Fields:
Translation:AnimalsCells - PSGL-1 Immune Checkpoint Inhibition for CD4+ T Cell Cancer Immunotherapy. Front Immunol. 2021; 12:636238. DeRogatis JM, Viramontes KM, Neubert EN, Tinoco R. PMID: 33708224; PMCID: PMC7940186.
View in: PubMed Mentions: 32 Fields:
Translation:HumansAnimalsCells - Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth. Cell Rep. 2020 02 11; 30(6):1753-1766.e6. Li Y, Elmén L, Segota I, Xian Y, Tinoco R, Feng Y, Fujita Y, Segura Muñoz RR, Schmaltz R, Bradley LM, Ramer-Tait A, Zarecki R, Long T, Peterson SN, Ronai ZA. PMID: 32049008; PMCID: PMC7053418.
View in: PubMed Mentions: 94 Fields:
Translation:Animals - Siah2 control of T-regulatory cells limits anti-tumor immunity. Nat Commun. 2020 01 07; 11(1):99. Scortegagna M, Hockemeyer K, Dolgalev I, Pozniak J, Rambow F, Li Y, Feng Y, Tinoco R, Otero DC, Zhang T, Brown K, Bosenberg M, Bradley LM, Marine JC, Aifantis I, Ronai ZA. PMID: 31911617; PMCID: PMC6946684.
View in: PubMed Mentions: 15 Fields:
Translation:HumansAnimalsCells - Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5-/- mice. Nat Commun. 2019 04 02; 10(1):1492. Li Y, Tinoco R, Elmén L, Segota I, Xian Y, Fujita Y, Sahu A, Zarecki R, Marie K, Feng Y, Khateb A, Frederick DT, Ashkenazi SK, Kim H, Perez EG, Day CP, Segura Muñoz RS, Schmaltz R, Yooseph S, Tam MA, Zhang T, Avitan-Hersh E, Tzur L, Roizman S, Boyango I, Bar-Sela G, Orian A, Kaufman RJ, Bosenberg M, Goding CR, Baaten B, Levesque MP, Dummer R, Brown K, Merlino G, Ruppin E, Flaherty K, Ramer-Tait A, Long T, Peterson SN, Bradley LM, Ronai ZA. PMID: 30940817; PMCID: PMC6445090.
View in: PubMed Mentions: 97 Fields:
Translation:HumansAnimalsCells - Ubiquitin Ligases in Cancer Immunotherapy - Balancing Antitumor and Autoimmunity. Trends Mol Med. 2019 05; 25(5):428-443. Fujita Y, Tinoco R, Li Y, Senft D, Ronai ZA. PMID: 30898473; PMCID: PMC6488401.
View in: PubMed Mentions: 31 Fields:
Translation:HumansAnimalsCells - Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis. Cell Rep. 2018 09 18; 24(12):3296-3311.e6. Fujita Y, Khateb A, Li Y, Tinoco R, Zhang T, Bar-Yoseph H, Tam MA, Chowers Y, Sabo E, Gerassy-Vainberg S, Starosvetsky E, James B, Brown K, Shen-Orr SS, Bradley LM, Tessier PA, Ronai ZA. PMID: 30232010; PMCID: PMC6185744.
View in: PubMed Mentions: 33 Fields:
Translation:HumansAnimalsCells - Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4+ T cell homeostasis. Nat Immunol. 2018 06; 19(6):594-605. Borlido J, Sakuma S, Raices M, Carrette F, Tinoco R, Bradley LM, D'Angelo MA. PMID: 29736031; PMCID: PMC5976539.
View in: PubMed Mentions: 24 Fields:
Translation:AnimalsCells - Fucosyltransferase Induction during Influenza Virus Infection Is Required for the Generation of Functional Memory CD4+ T Cells. J Immunol. 2018 04 15; 200(8):2690-2702. Tinoco R, Carrette F, Henriquez ML, Fujita Y, Bradley LM. PMID: 29491007; PMCID: PMC5890537.
View in: PubMed Mentions: 7 Fields:
Translation:AnimalsCells - Targeting the PSGL-1 pathway for immune modulation. Immunotherapy. 2017 09; 9(10):785-788. Tinoco R, Bradley LM. PMID: 28877633; PMCID: PMC5618955.
View in: PubMed Mentions: 6 Fields:
Translation:HumansAnimalsCells - PSGL-1: A New Player in the Immune Checkpoint Landscape. Trends Immunol. 2017 05; 38(5):323-335. Tinoco R, Otero DC, Takahashi AA, Bradley LM. PMID: 28262471; PMCID: PMC5411281.
View in: PubMed Mentions: 77 Fields:
Translation:HumansAnimalsCells - PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion. Immunity. 2016 Jun 21; 44(6):1470. Tinoco R, Carrette F, Barraza ML, Otero DC, Magaña J, Bosenberg MW, Swain SL, Bradley LM. PMID: 27332735.
View in: PubMed Mentions: 24 Fields: - PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion. Immunity. 2016 05 17; 44(5):1190-203. Tinoco R, Carrette F, Barraza ML, Otero DC, Magaña J, Bosenberg MW, Swain SL, Bradley LM. PMID: 27192578; PMCID: PMC4908967.
View in: PubMed Mentions: 82 Fields:
Translation:HumansAnimalsCells - Regulation of Antigen-Experienced T Cells: Lessons from the Quintessential Memory Marker CD44. Front Immunol. 2012; 3:23. Baaten BJ, Tinoco R, Chen AT, Bradley LM. PMID: 22566907; PMCID: PMC3342067.
View in: PubMed Mentions: 85 Fields: - Cell-intrinsic transforming growth factor-beta signaling mediates virus-specific CD8+ T cell deletion and viral persistence in vivo. Immunity. 2009 Jul 17; 31(1):145-57. Tinoco R, Alcalde V, Yang Y, Sauer K, Zuniga EI. PMID: 19604493; PMCID: PMC3039716.
View in: PubMed Mentions: 170 Fields:
Translation:AnimalsCells - Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor. Nat Immunol. 2009 Feb; 10(2):176-84. Kerdiles YM, Beisner DR, Tinoco R, Dejean AS, Castrillon DH, DePinho RA, Hedrick SM. PMID: 19136962; PMCID: PMC2856471.
View in: PubMed Mentions: 334 Fields:
Translation:AnimalsCells
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
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