Ali Khoshnan • USC Profiles (original) (raw)
- Epitope-specific antibodies can distinguish between soluble huntingtin exon-1 and its diverse cellular aggregates. J Biol Chem. 2026 Feb; 302(2):111048. Lugo J, Xu H, Chen J, Khoshnan A, Langen R. PMID: 41391760; PMCID: PMC12816906.
View in: PubMed Mentions: - Gut Microbiota as a Modifier of Huntington's Disease Pathogenesis. J Huntingtons Dis. 2024; 13(2):133-147. Khoshnan A. PMID: 38728199; PMCID: PMC11307070.
View in: PubMed Mentions: 7 Fields:
Translation:HumansAnimals - Corrigendum: Gut bacteria regulate the pathogenesis of Huntington's disease in Drosophila model. Front Neurosci. 2022; 16:991513. Chongtham A, Yoo JH, Chin TM, Akingbesote ND, Huda A, Marsh JL, Khoshnan A. PMID: 36312028; PMCID: PMC9611772.
View in: PubMed Mentions: 1 - Gut Bacteria Regulate the Pathogenesis of Huntington's Disease in Drosophila Model. Front Neurosci. 2022; 16:902205. Chongtham A, Yoo JH, Chin TM, Akingbesote ND, Huda A, Marsh JL, Khoshnan A. PMID: 35757549; PMCID: PMC9215115.
View in: PubMed Mentions: 17 - IKKβ signaling mediates metabolic changes in the hypothalamus of a Huntington disease mouse model. iScience. 2022 Feb 18; 25(2):103771. Soylu-Kucharz R, Khoshnan A, Petersén Å. PMID: 35146388; PMCID: PMC8819015.
View in: PubMed Mentions: 5 - Amplification of neurotoxic HTTex1 assemblies in human neurons. Neurobiol Dis. 2021 11; 159:105517. Chongtham A, Isas JM, Pandey NK, Rawat A, Yoo JH, Mastro T, Kennedy MB, Langen R, Khoshnan A. PMID: 34563643; PMCID: PMC8943833.
View in: PubMed Mentions: 5 Fields:
Translation:HumansAnimalsCells - Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of zQ175 Huntington's Disease Knock-in Mice. Front Neurosci. 2021; 15:682172. Schindler F, Praedel N, Neuendorf N, Kunz S, Schnoegl S, Mason MA, Taxy BA, Bates GP, Khoshnan A, Priller J, Grimm J, Maier M, Boeddrich A, Wanker EE. PMID: 34239412; PMCID: PMC8257939.
View in: PubMed Mentions: 7 - Identification of distinct conformations associated with monomers and fibril assemblies of mutant huntingtin. Hum Mol Genet. 2018 07 01; 27(13):2330-2343. Ko J, Isas JM, Sabbaugh A, Yoo JH, Pandey NK, Chongtham A, Ladinsky M, Wu WL, Rohweder H, Weiss A, Macdonald D, Munoz-Sanjuan I, Langen R, Patterson PH, Khoshnan A. PMID: 29912367; PMCID: PMC6005051.
View in: PubMed Mentions: 22 Fields:
Translation:HumansAnimalsCells - IKKβ and mutant huntingtin interactions regulate the expression of IL-34: implications for microglial-mediated neurodegeneration in HD. Hum Mol Genet. 2017 11 01; 26(21):4267-4277. Khoshnan A, Sabbaugh A, Calamini B, Marinero SA, Dunn DE, Yoo JH, Ko J, Lo DC, Patterson PH. PMID: 28973132; PMCID: PMC5886231.
View in: PubMed Mentions: 17 Fields:
Translation:HumansAnimalsCells - DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease. Hum Mol Genet. 2014 Feb 01; 23(3):755-66. Sajjad MU, Green EW, Miller-Fleming L, Hands S, Herrera F, Campesan S, Khoshnan A, Outeiro TF, Giorgini F, Wyttenbach A. PMID: 24070869.
View in: PubMed Mentions: 25 Fields:
Translation:HumansAnimalsCells - Antibodies and intrabodies against huntingtin: production and screening of monoclonals and single-chain recombinant forms. Methods Mol Biol. 2013; 1010:231-51. Khoshnan A, Ou S, Ko J, Patterson PH. PMID: 23754229.
View in: PubMed Mentions: 2 Fields:
Translation:HumansAnimalsCellsPHPublic Health - Elevated IKKα accelerates the differentiation of human neuronal progenitor cells and induces MeCP2-dependent BDNF expression. PLoS One. 2012; 7(7):e41794. Khoshnan A, Patterson PH. PMID: 22848609; PMCID: PMC3407048.
View in: PubMed Mentions: 12 Fields:
Translation:HumansAnimalsCells - The role of IκB kinase complex in the neurobiology of Huntington's disease. Neurobiol Dis. 2011 Aug; 43(2):305-11. Khoshnan A, Patterson PH. PMID: 21554955; PMCID: PMC3124142.
View in: PubMed Mentions: 27 Fields:
Translation:HumansAnimals - IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome. J Cell Biol. 2009 Dec 28; 187(7):1083-99. Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, Zeitlin SO, Finkbeiner S, Green KN, LaFerla FM, Bates G, Huang L, Patterson PH, Lo DC, Cuervo AM, Marsh JL, Steffan JS. PMID: 20026656; PMCID: PMC2806289.
View in: PubMed Mentions: 205 Fields:
Translation:HumansAnimalsCells - IKKalpha and IKKbeta regulation of DNA damage-induced cleavage of huntingtin. PLoS One. 2009 Jun 02; 4(6):e5768. Khoshnan A, Ko J, Tescu S, Brundin P, Patterson PH. PMID: 19488402; PMCID: PMC2685016.
View in: PubMed Mentions: 22 Fields:
Translation:HumansAnimalsCells - Intrabodies binding the proline-rich domains of mutant huntingtin increase its turnover and reduce neurotoxicity. J Neurosci. 2008 Sep 03; 28(36):9013-20. Southwell AL, Khoshnan A, Dunn DE, Bugg CW, Lo DC, Patterson PH. PMID: 18768695; PMCID: PMC2633448.
View in: PubMed Mentions: 62 Fields:
Translation:HumansAnimalsCells - Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity. J Neurosci. 2004 Sep 15; 24(37):7999-8008. Khoshnan A, Ko J, Watkin EE, Paige LA, Reinhart PH, Patterson PH. PMID: 15371500; PMCID: PMC6729796.
View in: PubMed Mentions: 114 Fields:
Translation:HumansAnimalsCells - Antibodies against huntingtin: production and screening of monoclonals and single-chain recombinant forms. Methods Mol Biol. 2004; 277:87-102. Khoshnan A, Ou S, Ko J, Patterson PH. PMID: 15201451.
View in: PubMed Mentions: Fields:
Translation:Humans - Effects of intracellular expression of anti-huntingtin antibodies of various specificities on mutant huntingtin aggregation and toxicity. Proc Natl Acad Sci U S A. 2002 Jan 22; 99(2):1002-7. Khoshnan A, Ko J, Patterson PH. PMID: 11792860; PMCID: PMC117420.
View in: PubMed Mentions: 56 Fields:
Translation:HumansCells - The physical association of protein kinase C theta with a lipid raft-associated inhibitor of kappa B factor kinase (IKK) complex plays a role in the activation of the NF-kappa B cascade by TCR and CD28. J Immunol. 2000 Dec 15; 165(12):6933-40. Khoshnan A, Bae D, Tindell CA, Nel AE. PMID: 11120819.
View in: PubMed Mentions: 29 Fields:
Translation:HumansCells - Response differences between human CD4(+) and CD8(+) T-cells during CD28 costimulation: implications for immune cell-based therapies and studies related to the expansion of double-positive T-cells during aging. Clin Immunol. 2000 Sep; 96(3):187-97. Laux I, Khoshnan A, Tindell C, Bae D, Zhu X, June CH, Effros RB, Nel A. PMID: 10964536.
View in: PubMed Mentions: 32 Fields:
Translation:HumansCells - The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes. J Immunol. 2000 Aug 15; 165(4):1743-54. Khoshnan A, Tindell C, Laux I, Bae D, Bennett B, Nel AE. PMID: 10925251.
View in: PubMed Mentions: 73 Fields:
Translation:HumansCells - Primary human CD4+ T cells contain heterogeneous I kappa B kinase complexes: role in activation of the IL-2 promoter. J Immunol. 1999 Nov 15; 163(10):5444-52. Khoshnan A, Kempiak SJ, Bennett BL, Bae D, Xu W, Manning AM, June CH, Nel AE. PMID: 10553070.
View in: PubMed Mentions: 5 Fields:
Translation:HumansCells - Hepatitis C virus core protein binds to the cytoplasmic domain of tumor necrosis factor (TNF) receptor 1 and enhances TNF-induced apoptosis. J Virol. 1998 May; 72(5):3691-7. Zhu N, Khoshnan A, Schneider R, Matsumoto M, Dennert G, Ware C, Lai MM. PMID: 9557650; PMCID: PMC109590.
View in: PubMed Mentions: 96 Fields: - Involvement of dsRNA virus in the protein composition and growth kinetics of host Trichomonas vaginalis. Arch Virol. 1997; 142(5):939-52. Provenzano D, Khoshnan A, Alderete JF. PMID: 9191859.
View in: PubMed Mentions: 29 Fields:
Translation:AnimalsCells - Characterization of double-stranded RNA satellites associated with the Trichomonas vaginalis virus. J Virol. 1995 Nov; 69(11):6892-7. Khoshnan A, Alderete JF. PMID: 7474105; PMCID: PMC189605.
View in: PubMed Mentions: 7 Fields:
Translation:AnimalsCells - Unique double-stranded RNAs associated with the Trichomonas vaginalis virus are synthesized by viral RNA-dependent RNA polymerase. J Virol. 1994 Nov; 68(11):7108-14. Khoshnan A, Provenzano D, Alderete JF. PMID: 7933092; PMCID: PMC237149.
View in: PubMed Mentions: 9 Fields:
Translation:HumansAnimalsCells - Trichomonas vaginalis with a double-stranded RNA virus has upregulated levels of phenotypically variable immunogen mRNA. J Virol. 1994 Jun; 68(6):4035-8. Khoshnan A, Alderete JF. PMID: 8189538; PMCID: PMC236912.
View in: PubMed Mentions: 36 Fields:
Translation:HumansAnimalsCells - Multiple double-stranded RNA segments are associated with virus particles infecting Trichomonas vaginalis. J Virol. 1993 Dec; 67(12):6950-5. Khoshnan A, Alderete JF. PMID: 8230417; PMCID: PMC238153.
View in: PubMed Mentions: 19 Fields:
Translation:AnimalsCells
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This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
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