Dhruv Sareen • UCLA Profiles (original) (raw)

  1. Charting the translational pathway: ISSCR best practices for the development of PSC-derived therapies. Stem Cell Reports. 2026 Feb 10; 21(2):102784. Barry J, Abranches E, Baptista RP, Barry C, Brandsten C, Bruce K, Carpenter MK, Cavagnaro J, Collins L, Csaszar E, Dashnau J, de Villa D, Fynes K, Gabaldo M, Hao J, Harel-Adar T, Hei D, Henchcliffe C, Hidalgo-Simon A, Hollands J, Hursh D, Jackman S, Kelly K, Kim JH, Kim H, Kino-Oka M, Lakshmipathy U, Lamb T, Lazic SE, Loring JF, Ludwig TE, Mariappan I, Monville C, Mountford JC, Nagy A, Okano H, Pellegrini G, Persson A, Prutton K, Rasko JEJ, Sareen D, Sato Y, Shnaiderman A, Stacey G, Svendsen CN, Tomishima M, Trounson A, Viswanathan S, Wang S, Wydenbach K, Zhang A, Zylberberg C, Mosher JT, Bharti K. PMID: 41576937; PMCID: PMC12903078.
    View in: PubMed Mentions: Fields:
    Translation:HumansCells
  2. Safety and tolerability of RPESC-RPE transplantation in patients with dry age-related macular degeneration: Low-dose clinical outcomes. Cell Stem Cell. 2025 Nov 06; 32(11):1659-1670.e4. Rao RC, Arduini BL, Borden S, Sareen D, Svendsen C, Lee P, Ryan C, Kodati S, Nyaiburi C, Wolsieffer K, Oh E, Park S, Ford G, Dionne K, Temple S, Stern J. PMID: 40961946; PMCID: PMC12533590.
    View in: PubMed Mentions: 1 Fields:
    Translation:HumansCellsCTClinical Trials
  3. Corrigendum to "Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data". Mol Cell Proteomics. 2025 Jul; 24(7):100995. Vidovic D, Shamsaei B, Schürer SC, Kogan P, Chojnacki S, Kouril M, Medvedovic M, Niu W, Azeloglu EU, Birtwistle MR, Chen Y, Chen T, Hansen J, Hu B, Iyengar R, Jayaraman G, Li H, Liu T, Sobie EA, Xiong Y, Berberich MJ, Bradshaw G, Chung M, Everley RA, Gaudio B, Hafner M, Kalocsay M, Mills CE, Nariya MK, Sorger PK, Subramanian K, Victor C, Banuelos M, Dardov V, Holewinski R, Manalo DM, Mandefro B, Matlock AD, Ornelas L, Sareen D, Svendsen CN, Vaibhav V, Van Eyk JE, Venkatraman V, Finkbiener S, Fraenkel E, Rothstein J, Thompson L, Asiedu J, Carr SA, Christianson KE, Davison D, Dele-Oni DO, DeRuff KC, Egri SB, Vaca Jacome AS, Jaffe JD, Lam D, Litichevskiy L, Lu X, Mullahoo J, Officer A, Papanastasiou M, Peckner R, Toder C, Blanchard J, Bula M, Ko T, Tsai LH, Young JZ, Sharma V, Meller J, MacCoss MJ. PMID: 40783300; PMCID: PMC12365493.
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  4. Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects. Neuron. 2025 Jun 18; 113(12):2028. Workman MJ, Lim RG, Wu J, Frank A, Ornelas L, Panther L, Galvez E, Perez D, Meepe I, Lei S, Valencia V, Gomez E, Liu C, Moran R, Pinedo L, Tsitkov S, Ho R, Kaye JA, Answer ALS Consortium, Thompson T, Rothstein JD, Finkbeiner S, Fraenkel E, Sareen D, Thompson LM, Svendsen CN. PMID: 40441139.
    View in: PubMed Mentions: Fields:
  5. Filamented Light (FLight) Biofabrication of Aligned Fibrillar Structures to Direct 3D Cell Organization Within Microgels. Small. 2025 Jul; 21(26):e2500261. Joshi A, Kamaraj M, Moghimi N, Heidari H, Aghamaleky-Sarvestany A, Rahim CSA, Rodriguez-Sanchez DN, Hu C, Aravindan S, Nair DSR, Huang NF, Thomas BB, Sareen D, Yoshihara E, Jucaud V, Khademhosseini A, V John J. PMID: 40346963.
    View in: PubMed Mentions: 1 Fields:
    Translation:AnimalsCells
  6. Comprehensive Proteomics Metadata and Integrative Web Portals Facilitate Sharing and Integration of LINCS Multiomics Data. Mol Cell Proteomics. 2025 Jul; 24(7):100947. Vidovic D, Shamsaei B, Schürer SC, Kogan P, Chojnacki S, Kouril M, Medvedovic M, Niu W, Azeloglu EU, Birtwistle MR, Chen Y, Chen T, Hansen J, Hu B, Iyengar R, Jayaraman G, Li H, Liu T, Sobie EA, Xiong Y, Berberich MJ, Bradshaw G, Chung M, Everley RA, Gaudio B, Hafner M, Kalocsay M, Mills CE, Nariya MK, Sorger PK, Subramanian K, Victor C, Banuelos M, Dardov V, Holewinski R, Manalo DM, Mandefro B, Matlock AD, Ornelas L, Sareen D, Svendsen CN, Vaibhav V, Van Eyk JE, Venkatraman V, Finkbiener S, Fraenkel E, Rothstein J, Thompson L, Asiedu J, Carr SA, Christianson KE, Davison D, Dele-Oni DO, DeRuff KC, Egri SB, Jacome ASV, Jaffe JD, Lam D, Litichevskiy L, Lu X, Mullahoo J, Officer A, Papanastasiou M, Peckner R, Toder C, Blanchard J, Bula M, Ko T, Tsai LH, Young JZ, Sharma V, Pillai A, Meller J, MacCoss MJ. PMID: 40089066; PMCID: PMC12332945.
    View in: PubMed Mentions: Fields:
    Translation:Humans
  7. Identification of Disease-Relevant, Sex-Based Proteomic Differences in iPSC-Derived Vascular Smooth Muscle Cells. Int J Mol Sci. 2024 Dec 29; 26(1). Ariyasinghe NR, Gupta D, Escopete S, Rai D, Stotland A, Sundararaman N, Ngu B, Dabke K, McCarthy L, Santos RS, McCain ML, Sareen D, Parker SJ. PMID: 39796045; PMCID: PMC11719605.
    View in: PubMed Mentions: 1 Fields:
    Translation:HumansCells
  8. Identification of Disease-relevant, Sex-based Proteomic Differences in iPSC-derived Vascular Smooth Muscle. bioRxiv. 2024 Aug 02. Ariyasinghe NR, Gupta D, Escopete S, Stotland AB, Sundararaman N, Ngu B, Dabke K, Rai D, McCarthy L, Santos RS, McCain ML, Sareen D, Parker SJ. PMID: 39211096; PMCID: PMC11361011.
    View in: PubMed Mentions:
  9. Disease related changes in ATAC-seq of iPSC-derived motor neuron lines from ALS patients and controls. Nat Commun. 2024 May 02; 15(1):3606. Tsitkov S, Valentine K, Kozareva V, Donde A, Frank A, Lei S, Answer ALS Consortium, E Van Eyk J, Finkbeiner S, Rothstein JD, Thompson LM, Sareen D, Svendsen CN, Fraenkel E. PMID: 38697975; PMCID: PMC11066062.
    View in: PubMed Mentions: 3 Fields:
    Translation:HumansCells
  10. Proteomics of novel induced pluripotent stem cell-derived vascular endothelial cells reveal extensive similarity with an immortalized human endothelial cell line. Physiol Genomics. 2023 08 01; 55(8):324-337. Ariyasinghe NR, de Souza Santos R, Gross A, Aghamaleky-Sarvestany A, Kreimer S, Escopete S, Parker SJ, Sareen D. PMID: 37306406; PMCID: PMC10396221.
    View in: PubMed Mentions: 3 Fields:
    Translation:HumansCells
  11. Generation of isogenic and homozygous MEN1 mutant cell lines from patient-derived iPSCs using CRISPR/Cas9. Stem Cell Res. 2023 06; 69:103124. Even-Zohar N, Metin-Armagan D, Ben-Shlomo A, Sareen D, Melmed S. PMID: 37209468; PMCID: PMC10882434.
    View in: PubMed Mentions: 1 Fields:
    Translation:HumansCells
  12. Large-scale differentiation of iPSC-derived motor neurons from ALS and control subjects. Neuron. 2023 04 19; 111(8):1191-1204.e5. Workman MJ, Lim RG, Wu J, Frank A, Ornelas L, Panther L, Galvez E, Perez D, Meepe I, Lei S, Valencia V, Gomez E, Liu C, Moran R, Pinedo L, Tsitkov S, Ho R, Kaye JA, Answer ALS Consortium, Thompson T, Rothstein JD, Finkbeiner S, Fraenkel E, Sareen D, Thompson LM, Svendsen CN. PMID: 36764301; PMCID: PMC10557526.
    View in: PubMed Mentions: 49 Fields:
    Translation:HumansCells
  13. NeuroLINCS Proteomics: Defining human-derived iPSC proteomes and protein signatures of pluripotency. Sci Data. 2023 01 11; 10(1):24. Matlock AD, Vaibhav V, Holewinski R, Venkatraman V, Dardov V, Manalo DM, Shelley B, Ornelas L, Banuelos M, Mandefro B, Escalante-Chong R, Li J, Finkbeiner S, Fraenkel E, Rothstein J, Thompson L, Sareen D, Svendsen CN, NIH NeuroLINCS Consortium, Van Eyk JE. PMID: 36631473; PMCID: PMC9834231.
    View in: PubMed Mentions: 4 Fields:
    Translation:HumansCells
  14. Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines. Nat Neurosci. 2022 02; 25(2):226-237. Baxi EG, Thompson T, Li J, Kaye JA, Lim RG, Wu J, Ramamoorthy D, Lima L, Vaibhav V, Matlock A, Frank A, Coyne AN, Landin B, Ornelas L, Mosmiller E, Thrower S, Farr SM, Panther L, Gomez E, Galvez E, Perez D, Meepe I, Lei S, Mandefro B, Trost H, Pinedo L, Banuelos MG, Liu C, Moran R, Garcia V, Workman M, Ho R, Wyman S, Roggenbuck J, Harms MB, Stocksdale J, Miramontes R, Wang K, Venkatraman V, Holewenski R, Sundararaman N, Pandey R, Manalo DM, Donde A, Huynh N, Adam M, Wassie BT, Vertudes E, Amirani N, Raja K, Thomas R, Hayes L, Lenail A, Cerezo A, Luppino S, Farrar A, Pothier L, Prina C, Morgan T, Jamil A, Heintzman S, Jockel-Balsarotti J, Karanja E, Markway J, McCallum M, Joslin B, Alibazoglu D, Kolb S, Ajroud-Driss S, Baloh R, Heitzman D, Miller T, Glass JD, Patel-Murray NL, Yu H, Sinani E, Vigneswaran P, Sherman AV, Ahmad O, Roy P, Beavers JC, Zeiler S, Krakauer JW, Agurto C, Cecchi G, Bellard M, Raghav Y, Sachs K, Ehrenberger T, Bruce E, Cudkowicz ME, Maragakis N, Norel R, Van Eyk JE, Finkbeiner S, Berry J, Sareen D, Thompson LM, Fraenkel E, Svendsen CN, Rothstein JD. PMID: 35115730; PMCID: PMC8825283.
    View in: PubMed Mentions: 82 Fields:
    Translation:HumansCells
  15. An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients. iScience. 2021 Nov 19; 24(11):103221. NeuroLINCS Consortium, Li J, Lim RG, Kaye JA, Dardov V, Coyne AN, Wu J, Milani P, Cheng A, Thompson TG, Ornelas L, Frank A, Adam M, Banuelos MG, Casale M, Cox V, Escalante-Chong R, Daigle JG, Gomez E, Hayes L, Holewenski R, Lei S, Lenail A, Lima L, Mandefro B, Matlock A, Panther L, Patel-Murray NL, Pham J, Ramamoorthy D, Sachs K, Shelley B, Stocksdale J, Trost H, Wilhelm M, Venkatraman V, Wassie BT, Wyman S, Yang S, NYGC ALS Consortium, Van Eyk JE, Lloyd TE, Finkbeiner S, Fraenkel E, Rothstein JD, Sareen D, Svendsen CN, Thompson LM. PMID: 34746695; PMCID: PMC8554488.
    View in: PubMed Mentions: 27
  16. Deleterious Effects of SARS-CoV-2 Infection on Human Pancreatic Cells. Front Cell Infect Microbiol. 2021; 11:678482. Shaharuddin SH, Wang V, Santos RS, Gross A, Wang Y, Jawanda H, Zhang Y, Hasan W, Garcia G, Arumugaswami V, Sareen D. PMID: 34282405; PMCID: PMC8285288.
    View in: PubMed Mentions: 36 Fields:
    Translation:HumansCellsPHPublic Health
  17. Hypothalamus and neuroendocrine diseases: The use of human-induced pluripotent stem cells for disease modeling. Handb Clin Neurol. 2021; 181:337-350. de Souza Santos R, Gross AR, Sareen D. PMID: 34238469.
    View in: PubMed Mentions: 1 Fields:
    Translation:HumansAnimalsCells
  18. G4C2 Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD. Neuron. 2020 09 23; 107(6):1124-1140.e11. Coyne AN, Zaepfel BL, Hayes L, Fitchman B, Salzberg Y, Luo EC, Bowen K, Trost H, Aigner S, Rigo F, Yeo GW, Harel A, Svendsen CN, Sareen D, Rothstein JD. PMID: 32673563; PMCID: PMC8077944.
    View in: PubMed Mentions: 99 Fields:
    Translation:HumansCells
  19. Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns. Mol Autism. 2020 06 19; 11(1):52. Das Sharma S, Pal R, Reddy BK, Selvaraj BT, Raj N, Samaga KK, Srinivasan DJ, Ornelas L, Sareen D, Livesey MR, Bassell GJ, Svendsen CN, Kind PC, Chandran S, Chattarji S, Wyllie DJA. PMID: 32560741; PMCID: PMC7304215.
    View in: PubMed Mentions: 14 Fields:
    Translation:HumansAnimalsCells
  20. Immunosuppressive Functions of M2 Macrophages Derived from iPSCs of Patients with ALS and Healthy Controls. iScience. 2020 Jun 26; 23(6):101192. Zhao W, Beers DR, Thonhoff JR, Thome AD, Faridar A, Wang J, Wen S, Ornelas L, Sareen D, Goodridge HS, Svendsen CN, Appel SH. PMID: 32521508; PMCID: PMC7286967.
    View in: PubMed Mentions: 21
  21. Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936. Stem Cell Res. 2020 07; 46:101851. Toombs J, Panther L, Ornelas L, Liu C, Gomez E, Martín-Ibáñez R, Cox SR, Ritchie SJ, Harris SE, Taylor A, Redmond P, Russ TC, Murphy L, Cooper JD, Burr K, Selvaraj BT, Browne C, Svendsen CN, Cowley SA, Deary IJ, Chandran S, Spires-Jones TL, Sareen D. PMID: 32450543; PMCID: PMC7347008.
    View in: PubMed Mentions: 17 Fields:
    Translation:Cells
  22. Retraction Note: Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives. Nat Commun. 2019 Feb 02; 10(1):645. Rajamani U, Gross AR, Ocampo C, Andres AM, Gottlieb RA, Sareen D. PMID: 30712056; PMCID: PMC6359997.
    View in: PubMed Mentions: Fields:
  23. Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses. Cell Stem Cell. 2018 05 03; 22(5):698-712.e9. Rajamani U, Gross AR, Hjelm BE, Sequeira A, Vawter MP, Tang J, Gangalapudi V, Wang Y, Andres AM, Gottlieb RA, Sareen D. PMID: 29681516; PMCID: PMC6398951.
    View in: PubMed Mentions: 35 Fields:
    Translation:HumansCells
  24. Human iPSC-Derived Endothelial Cells and Microengineered Organ-Chip Enhance Neuronal Development. Stem Cell Reports. 2018 04 10; 10(4):1222-1236. Sances S, Ho R, Vatine G, West D, Laperle A, Meyer A, Godoy M, Kay PS, Mandefro B, Hatata S, Hinojosa C, Wen N, Sareen D, Hamilton GA, Svendsen CN. PMID: 29576540; PMCID: PMC5998748.
    View in: PubMed Mentions: 82 Fields:
    Translation:HumansCells
  25. The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations. Cell Syst. 2018 01 24; 6(1):13-24. Keenan AB, Jenkins SL, Jagodnik KM, Koplev S, He E, Torre D, Wang Z, Dohlman AB, Silverstein MC, Lachmann A, Kuleshov MV, Ma'ayan A, Stathias V, Terryn R, Cooper D, Forlin M, Koleti A, Vidovic D, Chung C, Schürer SC, Vasiliauskas J, Pilarczyk M, Shamsaei B, Fazel M, Ren Y, Niu W, Clark NA, White S, Mahi N, Zhang L, Kouril M, Reichard JF, Sivaganesan S, Medvedovic M, Meller J, Koch RJ, Birtwistle MR, Iyengar R, Sobie EA, Azeloglu EU, Kaye J, Osterloh J, Haston K, Kalra J, Finkbiener S, Li J, Milani P, Adam M, Escalante-Chong R, Sachs K, Lenail A, Ramamoorthy D, Fraenkel E, Daigle G, Hussain U, Coye A, Rothstein J, Sareen D, Ornelas L, Banuelos M, Mandefro B, Ho R, Svendsen CN, Lim RG, Stocksdale J, Casale MS, Thompson TG, Wu J, Thompson LM, Dardov V, Venkatraman V, Matlock A, Van Eyk JE, Jaffe JD, Papanastasiou M, Subramanian A, Golub TR, Erickson SD, Fallahi-Sichani M, Hafner M, Gray NS, Lin JR, Mills CE, Muhlich JL, Niepel M, Shamu CE, Williams EH, Wrobel D, Sorger PK, Heiser LM, Gray JW, Korkola JE, Mills GB, LaBarge M, Feiler HS, Dane MA, Bucher E, Nederlof M, Sudar D, Gross S, Kilburn DF, Smith R, Devlin K, Margolis R, Derr L, Lee A, Pillai A. PMID: 29199020; PMCID: PMC5799026.
    View in: PubMed Mentions: 234 Fields:
    Translation:HumansCells
  26. A Comparison of mRNA Sequencing with Random Primed and 3'-Directed Libraries. Sci Rep. 2017 11 07; 7(1):14626. Xiong Y, Soumillon M, Wu J, Hansen J, Hu B, van Hasselt JGC, Jayaraman G, Lim R, Bouhaddou M, Ornelas L, Bochicchio J, Lenaeus L, Stocksdale J, Shim J, Gomez E, Sareen D, Svendsen C, Thompson LM, Mahajan M, Iyengar R, Sobie EA, Azeloglu EU, Birtwistle MR. PMID: 29116112; PMCID: PMC5676863.
    View in: PubMed Mentions: 34 Fields:
    Translation:HumansCells
  27. Directed Differentiation of Human Induced Pluripotent Stem Cells into Fallopian Tube Epithelium. Sci Rep. 2017 09 06; 7(1):10741. Yucer N, Holzapfel M, Jenkins Vogel T, Lenaeus L, Ornelas L, Laury A, Sareen D, Barrett R, Karlan BY, Svendsen CN. PMID: 28878359; PMCID: PMC5587694.
    View in: PubMed Mentions: 43 Fields:
    Translation:HumansCells
  28. Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives. Nat Commun. 2017 08 09; 8(1):219. Rajamani U, Gross AR, Ocampo C, Andres AM, Gottlieb RA, Sareen D. PMID: 28794470; PMCID: PMC5550485.
    View in: PubMed Mentions: 3 Fields:
    Translation:HumansCells
  29. Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy. Proc Natl Acad Sci U S A. 2017 02 21; 114(8):E1509-E1518. Woo CJ, Maier VK, Davey R, Brennan J, Li G, Brothers J, Schwartz B, Gordo S, Kasper A, Okamoto TR, Johansson HE, Mandefro B, Sareen D, Bialek P, Chau BN, Bhat B, Bullough D, Barsoum J. PMID: 28193854; PMCID: PMC5338378.
    View in: PubMed Mentions: 53 Fields:
    Translation:HumansAnimalsCells
  30. Differentiation of Human Induced Pluripotent Stem Cells to Mammary-like Organoids. Stem Cell Reports. 2017 02 14; 8(2):205-215. Qu Y, Han B, Gao B, Bose S, Gong Y, Wawrowsky K, Giuliano AE, Sareen D, Cui X. PMID: 28132888; PMCID: PMC5312254.
    View in: PubMed Mentions: 42 Fields:
    Translation:HumansCells
  31. Transcriptome and proteome characterization of surface ectoderm cells differentiated from human iPSCs. Sci Rep. 2016 08 23; 6:32007. Qu Y, Zhou B, Yang W, Han B, Yu-Rice Y, Gao B, Johnson J, Svendsen CN, Freeman MR, Giuliano AE, Sareen D, Cui X. PMID: 27550649; PMCID: PMC4994084.
    View in: PubMed Mentions: 22 Fields:
    Translation:HumansCells
  32. Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease. Nucleic Acids Res. 2016 12 15; 44(22):10960-10973. Vazquez-Arango P, Vowles J, Browne C, Hartfield E, Fernandes HJ, Mandefro B, Sareen D, James W, Wade-Martins R, Cowley SA, Murphy S, O'Reilly D. PMID: 27536002; PMCID: PMC5159530.
    View in: PubMed Mentions: 22 Fields:
    Translation:HumansCells
  33. ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks. Nat Neurosci. 2016 09; 19(9):1256-67. Ho R, Sances S, Gowing G, Amoroso MW, O'Rourke JG, Sahabian A, Wichterle H, Baloh RH, Sareen D, Svendsen CN. PMID: 27428653; PMCID: PMC5003654.
    View in: PubMed Mentions: 71 Fields:
    Translation:HumansCells
  34. Human Induced Pluripotent Stem Cells Differentiate Into Functional Mesenchymal Stem Cells and Repair Bone Defects. Stem Cells Transl Med. 2016 Nov; 5(11):1447-1460. Sheyn D, Ben-David S, Shapiro G, De Mel S, Bez M, Ornelas L, Sahabian A, Sareen D, Da X, Pelled G, Tawackoli W, Liu Z, Gazit D, Gazit Z. PMID: 27400789; PMCID: PMC5070500.
    View in: PubMed Mentions: 81 Fields:
  35. Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells. Sci Rep. 2016 05 05; 6:25474. Milani P, Escalante-Chong R, Shelley BC, Patel-Murray NL, Xin X, Adam M, Mandefro B, Sareen D, Svendsen CN, Fraenkel E. PMID: 27146274; PMCID: PMC4857123.
    View in: PubMed Mentions: 30 Fields:
    Translation:HumansCells
  36. Modeling ALS with motor neurons derived from human induced pluripotent stem cells. Nat Neurosci. 2016 Apr; 19(4):542-53. Sances S, Bruijn LI, Chandran S, Eggan K, Ho R, Klim JR, Livesey MR, Lowry E, Macklis JD, Rushton D, Sadegh C, Sareen D, Wichterle H, Zhang SC, Svendsen CN. PMID: 27021939; PMCID: PMC5015775.
    View in: PubMed Mentions: 168 Fields:
    Translation:HumansAnimalsCells
  37. Spinal Muscular Atrophy Patient iPSC-Derived Motor Neurons Have Reduced Expression of Proteins Important in Neuronal Development. Front Cell Neurosci. 2015; 9:506. Fuller HR, Mandefro B, Shirran SL, Gross AR, Kaus AS, Botting CH, Morris GE, Sareen D. PMID: 26793058; PMCID: PMC4707261.
    View in: PubMed Mentions: 44
  38. ALS Patient Stem Cells for Unveiling Disease Signatures of Motoneuron Susceptibility: Perspectives on the Deadly Mitochondria, ER Stress and Calcium Triad. Front Cell Neurosci. 2015; 9:448. Kaus A, Sareen D. PMID: 26635528; PMCID: PMC4652136.
    View in: PubMed Mentions: 25
  39. Low-Dose Irradiation Enhances Gene Targeting in Human Pluripotent Stem Cells. Stem Cells Transl Med. 2015 Sep; 4(9):998-1010. Hatada S, Subramanian A, Mandefro B, Ren S, Kim HW, Tang J, Funari V, Baloh RH, Sareen D, Arumugaswami V, Svendsen CN. PMID: 26185257; PMCID: PMC4542875.
    View in: PubMed Mentions: 8 Fields:
    Translation:HumansCells
  40. Human iPSC-Derived Neural Progenitors Preserve Vision in an AMD-Like Model. Stem Cells. 2015 Aug; 33(8):2537-49. Tsai Y, Lu B, Bakondi B, Girman S, Sahabian A, Sareen D, Svendsen CN, Wang S. PMID: 25869002; PMCID: PMC5477659.
    View in: PubMed Mentions: 31 Fields:
    Translation:HumansAnimalsCells
  41. HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity. Hum Mol Genet. 2015 Jun 01; 24(11):3257-71. Mattis VB, Tom C, Akimov S, Saeedian J, Østergaard ME, Southwell AL, Doty CN, Ornelas L, Sahabian A, Lenaeus L, Mandefro B, Sareen D, Arjomand J, Hayden MR, Ross CA, Svendsen CN. PMID: 25740845; PMCID: PMC4424959.
    View in: PubMed Mentions: 72 Fields:
    Translation:HumansAnimalsCells
  42. Reliable generation of induced pluripotent stem cells from human lymphoblastoid cell lines. Stem Cells Transl Med. 2014 Dec; 3(12):1429-34. Barrett R, Ornelas L, Yeager N, Mandefro B, Sahabian A, Lenaeus L, Targan SR, Svendsen CN, Sareen D. PMID: 25298370; PMCID: PMC4250214.
    View in: PubMed Mentions: 54 Fields:
    Translation:HumansCells
  43. Differentiation of human limbal-derived induced pluripotent stem cells into limbal-like epithelium. Stem Cells Transl Med. 2014 Sep; 3(9):1002-12. Sareen D, Saghizadeh M, Ornelas L, Winkler MA, Narwani K, Sahabian A, Funari VA, Tang J, Spurka L, Punj V, Maguen E, Rabinowitz YS, Svendsen CN, Ljubimov AV. PMID: 25069777; PMCID: PMC4149305.
    View in: PubMed Mentions: 49 Fields:
    Translation:HumansCells
  44. miR-409-3p/-5p promotes tumorigenesis, epithelial-to-mesenchymal transition, and bone metastasis of human prostate cancer. Clin Cancer Res. 2014 Sep 01; 20(17):4636-46. Josson S, Gururajan M, Hu P, Shao C, Chu GY, Zhau HE, Liu C, Lao K, Lu CL, Lu YT, Lichterman J, Nandana S, Li Q, Rogatko A, Berel D, Posadas EM, Fazli L, Sareen D, Chung LW. PMID: 24963047; PMCID: PMC4155061.
    View in: PubMed Mentions: 89 Fields:
    Translation:HumansAnimalsCells
  45. Human induced pluripotent stem cells are a novel source of neural progenitor cells (iNPCs) that migrate and integrate in the rodent spinal cord. J Comp Neurol. 2014 Aug 15; 522(12):2707-28. Sareen D, Gowing G, Sahabian A, Staggenborg K, Paradis R, Avalos P, Latter J, Ornelas L, Garcia L, Svendsen CN. PMID: 24610630; PMCID: PMC4070510.
    View in: PubMed Mentions: 71 Fields:
    Translation:HumansAnimalsCells
  46. Patient-derived skeletal dysplasia induced pluripotent stem cells display abnormal chondrogenic marker expression and regulation by BMP2 and TGFβ1. Stem Cells Dev. 2014 Jul 01; 23(13):1464-78. Saitta B, Passarini J, Sareen D, Ornelas L, Sahabian A, Argade S, Krakow D, Cohn DH, Svendsen CN, Rimoin DL. PMID: 24559391; PMCID: PMC4066255.
    View in: PubMed Mentions: 29 Fields:
    Translation:HumansCells
  47. Neonatal immune-tolerance in mice does not prevent xenograft rejection. Exp Neurol. 2014 Apr; 254:90-8. Mattis VB, Wakeman DR, Tom C, Dodiya HB, Yeung SY, Tran AH, Bernau K, Ornelas L, Sahabian A, Reidling J, Sareen D, Thompson LM, Kordower JH, Svendsen CN. PMID: 24440640; PMCID: PMC3954854.
    View in: PubMed Mentions: 15 Fields:
    Translation:HumansAnimalsCells
  48. A simple alkaline method for decellularizing human amniotic membrane for cell culture. PLoS One. 2013; 8(11):e79632. Saghizadeh M, Winkler MA, Kramerov AA, Hemmati DM, Ghiam CA, Dimitrijevich SD, Sareen D, Ornelas L, Ghiasi H, Brunken WJ, Maguen E, Rabinowitz YS, Svendsen CN, Jirsova K, Ljubimov AV. PMID: 24236148; PMCID: PMC3827346.
    View in: PubMed Mentions: 27 Fields:
    Translation:HumansCells
  49. Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion. Sci Transl Med. 2013 Oct 23; 5(208):208ra149. Sareen D, O'Rourke JG, Meera P, Muhammad AK, Grant S, Simpkinson M, Bell S, Carmona S, Ornelas L, Sahabian A, Gendron T, Petrucelli L, Baughn M, Ravits J, Harms MB, Rigo F, Bennett CF, Otis TS, Svendsen CN, Baloh RH. PMID: 24154603; PMCID: PMC4090945.
    View in: PubMed Mentions: 413 Fields:
    Translation:HumansCells
  50. EZ spheres: a stable and expandable culture system for the generation of pre-rosette multipotent stem cells from human ESCs and iPSCs. Stem Cell Res. 2013 May; 10(3):417-427. Ebert AD, Shelley BC, Hurley AM, Onorati M, Castiglioni V, Patitucci TN, Svendsen SP, Mattis VB, McGivern JV, Schwab AJ, Sareen D, Kim HW, Cattaneo E, Svendsen CN. PMID: 23474892; PMCID: PMC3786426.
    View in: PubMed Mentions: 66 Fields:
    Translation:HumansCells
  51. Inhibition of apoptosis blocks human motor neuron cell death in a stem cell model of spinal muscular atrophy. PLoS One. 2012; 7(6):e39113. Sareen D, Ebert AD, Heins BM, McGivern JV, Ornelas L, Svendsen CN. PMID: 22723941; PMCID: PMC3378532.
    View in: PubMed Mentions: 89 Fields:
    Translation:HumansCells
  52. Gene therapy-mediated delivery of targeted cytotoxins for glioma therapeutics. Proc Natl Acad Sci U S A. 2010 Nov 16; 107(46):20021-6. Candolfi M, Xiong W, Yagiz K, Liu C, Muhammad AK, Puntel M, Foulad D, Zadmehr A, Ahlzadeh GE, Kroeger KM, Tesarfreund M, Lee S, Debinski W, Sareen D, Svendsen CN, Rodriguez R, Lowenstein PR, Castro MG. PMID: 21030678; PMCID: PMC2993419.
    View in: PubMed Mentions: 54 Fields:
    Translation:HumansAnimalsCells
  53. Stem cell biologists sure play a mean pinball. Nat Biotechnol. 2010 Apr; 28(4):333-5. Sareen D, Svendsen CN. PMID: 20379177; PMCID: PMC3142542.
    View in: PubMed Mentions: 6 Fields:
    Translation:AnimalsCells
  54. Chromosome 7 and 19 trisomy in cultured human neural progenitor cells. PLoS One. 2009 Oct 29; 4(10):e7630. Sareen D, McMillan E, Ebert AD, Shelley BC, Johnson JA, Meisner LF, Svendsen CN. PMID: 19898616; PMCID: PMC2765070.
    View in: PubMed Mentions: 31 Fields:
    Translation:HumansCells
  55. Resveratrol inhibits uveal melanoma tumor growth via early mitochondrial dysfunction. Invest Ophthalmol Vis Sci. 2008 Apr; 49(4):1299-306. van Ginkel PR, Darjatmoko SR, Sareen D, Subramanian L, Bhattacharya S, Lindstrom MJ, Albert DM, Polans AS. PMID: 18385041; PMCID: PMC2465765.
    View in: PubMed Mentions: 30 Fields:
    Translation:AnimalsCells
  56. Mitochondria, calcium, and calpain are key mediators of resveratrol-induced apoptosis in breast cancer. Mol Pharmacol. 2007 Dec; 72(6):1466-75. Sareen D, Darjatmoko SR, Albert DM, Polans AS. PMID: 17848600.
    View in: PubMed Mentions: 69 Fields:
    Translation:HumansAnimalsCells
  57. Resveratrol inhibits tumor growth of human neuroblastoma and mediates apoptosis by directly targeting mitochondria. Clin Cancer Res. 2007 Sep 01; 13(17):5162-9. van Ginkel PR, Sareen D, Subramanian L, Walker Q, Darjatmoko SR, Lindstrom MJ, Kulkarni A, Albert DM, Polans AS. PMID: 17785572.
    View in: PubMed Mentions: 77 Fields:
    Translation:HumansAnimalsCells
  58. Mitochondria as the primary target of resveratrol-induced apoptosis in human retinoblastoma cells. Invest Ophthalmol Vis Sci. 2006 Sep; 47(9):3708-16. Sareen D, van Ginkel PR, Takach JC, Mohiuddin A, Darjatmoko SR, Albert DM, Polans AS. PMID: 16936077.
    View in: PubMed Mentions: 38 Fields:
    Translation:HumansCells
  59. Serum cholesterol levels in the population of Punjab in north west India. Am J Clin Nutr. 1978 Aug; 31(8):1479-83. Werner GT, Sareen DK. PMID: 677088.
    View in: PubMed Mentions: 1 Fields:
    Translation:Humans

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