Liana Chan • UCLA Profiles (original) (raw)

  1. SARS-CoV-2 peptide fragments selectively dysregulate specific immune cell populations via Gaussian curvature targeting. Proc Natl Acad Sci U S A. 2026 Jan 13; 123(2):e2521841122. Zhang Y, Silvestre-Roig C, Fu H, Alimohamadi H, Mandal T, Chen JW, Luo EW, Anda J, Linard Matos AL, Richter M, Mennella A, Lee H, Chan LC, Wang Y, Wang N, Wang H, Wang X, Lee CK, Ghosh S, Matsui T, Weiss TM, Guo T, Zhang M, Li D, Wolfgang MC, Hagan RS, Li MMH, Gunzer M, Sickmann A, Frasca L, Yeaman MR, Lande R, Cui Q, Soehnlein O, Wong GCL. PMID: 41505524; PMCID: PMC12799121.
    View in: PubMed Mentions: Fields:
    Translation:HumansCells
  2. Early cytokine signatures and clinical phenotypes discriminate persistent from resolving MRSA bacteremia. BMC Infect Dis. 2025 Feb 18; 25(1):231. Bergersen KV, Zheng Y, Rossetti M, Ruffin F, Pickering H, Parmar R, Sunga G, Chan LC, Gjertson D, Fowler VG, Yeaman MR, Reed EF, MRSA Systems Immunobiology Group. PMID: 39966757; PMCID: PMC11834594.
    View in: PubMed Mentions: 2 Fields:
    Translation:HumansCells
  3. Integrated transcriptomic analysis reveals immune signatures distinguishing persistent versus resolving outcomes in MRSA bacteremia. Front Immunol. 2024; 15:1373553. Parmar R, Pickering H, Ahn R, Rossetti M, Gjertson DW, Ruffin F, Chan LC, Fowler VG, Yeaman MR, Reed EF, MRSA Systems Immunology Group. PMID: 38846955; PMCID: PMC11153731.
    View in: PubMed Mentions: 2 Fields:
    Translation:HumansCells
  4. Tensor modeling of MRSA bacteremia cytokine and transcriptional patterns reveals coordinated, outcome-associated immunological programs. PNAS Nexus. 2024 May; 3(5):pgae185. Chin JL, Tan ZC, Chan LC, Ruffin F, Parmar R, Ahn R, Taylor SD, Bayer AS, Hoffmann A, Fowler VG, Reed EF, Yeaman MR, Meyer AS, with the MRSA Systems Immunobiology Group . PMID: 38779114; PMCID: PMC11109816.
    View in: PubMed Mentions: 4
  5. Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes. Proc Natl Acad Sci U S A. 2024 Feb 06; 121(6):e2300644120. Zhang Y, Bharathi V, Dokoshi T, de Anda J, Ursery LT, Kulkarni NN, Nakamura Y, Chen J, Luo EWC, Wang L, Xu H, Coady A, Zurich R, Lee MW, Matsui T, Lee H, Chan LC, Schepmoes AA, Lipton MS, Zhao R, Adkins JN, Clair GC, Thurlow LR, Schisler JC, Wolfgang MC, Hagan RS, Yeaman MR, Weiss TM, Chen X, Li MMH, Nizet V, Antoniak S, Mackman N, Gallo RL, Wong GCL. PMID: 38306481; PMCID: PMC10861912.
    View in: PubMed Mentions: 15 Fields:
    Translation:HumansAnimalsCells
  6. Diflunisal and Analogue Pharmacophores Mediating Suppression of Virulence Phenotypes in Staphylococcus aureus. Antibiotics (Basel). 2023 Jul 12; 12(7). Chan LC, Lee HK, Wang L, Chaili S, Xiong YQ, Bayer AS, Proctor RA, Yeaman MR. PMID: 37508276; PMCID: PMC10376238.
    View in: PubMed Mentions: 2
  7. Diflunisal Attenuates Virulence Factor Gene Regulation and Phenotypes in Staphylococcus aureus. Antibiotics (Basel). 2023 May 13; 12(5). Chan LC, Park M, Lee HK, Chaili S, Xiong YQ, Bayer AS, Proctor RA, Yeaman MR. PMID: 37237805; PMCID: PMC10215304.
    View in: PubMed Mentions: 3
  8. Tensor-based insights into systems immunity and infectious disease. Trends Immunol. 2023 05; 44(5):329-332. Chin JL, Chan LC, Yeaman MR, Meyer AS. PMID: 36997459; PMCID: PMC10411872.
    View in: PubMed Mentions: 9 Fields:
    Translation:Humans
  9. MRSA Isolates from Patients with Persistent Bacteremia Generate Nonstable Small Colony Variants In Vitro within Macrophages and Endothelial Cells during Prolonged Vancomycin Exposure. Infect Immun. 2023 01 24; 91(1):e0042322. Fauerharmel-Nunes T, Flannagan RS, Goncheva MI, Bayer AS, Fowler VG, Chan LC, Yeaman MR, Xiong YQ, Heinrichs DE. PMID: 36602380; PMCID: PMC9872686.
    View in: PubMed Mentions: 6 Fields:
    Translation:HumansCells
  10. Staphylococcus aureus adaptive evolution: Recent insights on how immune evasion, immunometabolic subversion and host genetics impact vaccine development. Front Cell Infect Microbiol. 2022; 12:1060810. Wong Fok Lung T, Chan LC, Prince A, Yeaman MR, Archer NK, Aman MJ, Proctor RA. PMID: 36636720; PMCID: PMC9831658.
    View in: PubMed Mentions: 19 Fields:
    Translation:HumansCells
  11. Impacts of NaHCO3 on β-Lactam Binding to PBP2a Protein Variants Associated with the NaHCO3-Responsive versus NaHCO3-Non-Responsive Phenotypes. Antibiotics (Basel). 2022 Mar 30; 11(4). Ersoy SC, Chan LC, Yeaman MR, Chambers HF, Proctor RA, Ludwig KC, Schneider T, Manna AC, Cheung A, Bayer AS. PMID: 35453214; PMCID: PMC9028190.
    View in: PubMed Mentions: 9
  12. Mechanistic Fingerprinting Reveals Kinetic Signatures of Resistance to Daptomycin and Host Defense Peptides in Streptococcus mitis-oralis. Antibiotics (Basel). 2021 Apr 08; 10(4). Yeaman MR, Chan LC, Mishra NN, Bayer AS. PMID: 33918000; PMCID: PMC8068394.
    View in: PubMed Mentions: 2
  13. PACAP is a pathogen-inducible resident antimicrobial neuropeptide affording rapid and contextual molecular host defense of the brain. Proc Natl Acad Sci U S A. 2021 01 05; 118(1). Lee EY, Chan LC, Wang H, Lieng J, Hung M, Srinivasan Y, Wang J, Waschek JA, Ferguson AL, Lee KF, Yount NY, Yeaman MR, Wong GCL. PMID: 33372152; PMCID: PMC7817161.
    View in: PubMed Mentions: 24 Fields:
    Translation:AnimalsCells
  14. Genetic variation of DNA methyltransferase-3A contributes to protection against persistent MRSA bacteremia in patients. Proc Natl Acad Sci U S A. 2019 10 01; 116(40):20087-20096. Mba Medie F, Sharma-Kuinkel BK, Ruffin F, Chan LC, Rossetti M, Chang YL, Park LP, Bayer AS, Filler SG, Ahn R, Reed EF, Gjertson D, Yeaman MR, Fowler VG, MRSA Systems Immunobiology Group. PMID: 31527248; PMCID: PMC6778225.
    View in: PubMed Mentions: 21 Fields:
    Translation:HumansCells
  15. Unifying structural signature of eukaryotic α-helical host defense peptides. Proc Natl Acad Sci U S A. 2019 04 02; 116(14):6944-6953. Yount NY, Weaver DC, Lee EY, Lee MW, Wang H, Chan LC, Wong GCL, Yeaman MR. PMID: 30877253; PMCID: PMC6452647.
    View in: PubMed Mentions: 24 Fields:
    Translation:Cells
  16. Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory. Proc Natl Acad Sci U S A. 2018 11 20; 115(47):E11111-E11119. Chan LC, Rossetti M, Miller LS, Filler SG, Johnson CW, Lee HK, Wang H, Gjertson D, Fowler VG, Reed EF, Yeaman MR, MRSA Systems Immunobiology Group. PMID: 30297395; PMCID: PMC6255181.
    View in: PubMed Mentions: 54 Fields:
    Translation:AnimalsCells
  17. Innate Immune Memory Contributes to Host Defense against Recurrent Skin and Skin Structure Infections Caused by Methicillin-Resistant Staphylococcus aureus. Infect Immun. 2017 02; 85(2). Chan LC, Chaili S, Filler SG, Miller LS, Solis NV, Wang H, Johnson CW, Lee HK, Diaz LF, Yeaman MR. PMID: 27849182; PMCID: PMC5278165.
    View in: PubMed Mentions: 34 Fields:
    Translation:AnimalsCells
  18. PBP 4 Mediates High-Level Resistance to New-Generation Cephalosporins in Staphylococcus aureus. Antimicrob Agents Chemother. 2016 07; 60(7):3934-41. Chan LC, Gilbert A, Basuino L, da Costa TM, Hamilton SM, Dos Santos KR, Chambers HF, Chatterjee SS. PMID: 27067335; PMCID: PMC4914628.
    View in: PubMed Mentions: 19 Fields:
    Translation:Cells
  19. Whole-Genome Sequencing of Methicillin-Resistant Staphylococcus aureus Resistant to Fifth-Generation Cephalosporins Reveals Potential Non-mecA Mechanisms of Resistance. PLoS One. 2016; 11(2):e0149541. Greninger AL, Chatterjee SS, Chan LC, Hamilton SM, Chambers HF, Chiu CY. PMID: 26890675; PMCID: PMC4758708.
    View in: PubMed Mentions: 35 Fields:
    Translation:Cells
  20. Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus. Infect Immun. 2015 Nov; 83(11):4427-37. Chan LC, Chaili S, Filler SG, Barr K, Wang H, Kupferwasser D, Edwards JE, Xiong YQ, Ibrahim AS, Miller LS, Schmidt CS, Hennessey JP, Yeaman MR. PMID: 26351278; PMCID: PMC4598415.
    View in: PubMed Mentions: 37 Fields:
    Translation:HumansAnimalsCells
  21. Comparative efficacies of tedizolid phosphate, vancomycin, and daptomycin in a rabbit model of methicillin-resistant Staphylococcus aureus endocarditis. Antimicrob Agents Chemother. 2015; 59(6):3252-6. Chan LC, Basuino L, Dip EC, Chambers HF. PMID: 25801564; PMCID: PMC4432129.
    View in: PubMed Mentions: 13 Fields:
    Translation:AnimalsCells
  22. Ceftobiprole- and ceftaroline-resistant methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2015 May; 59(5):2960-3. Chan LC, Basuino L, Diep B, Hamilton S, Chatterjee SS, Chambers HF. PMID: 25753637; PMCID: PMC4394828.
    View in: PubMed Mentions: 42 Fields:
    Translation:Cells
  23. Global gene expression of methicillin-resistant Staphylococcus aureus USA300 during human and mouse infection. J Infect Dis. 2014 May 15; 209(10):1542-50. Date SV, Modrusan Z, Lawrence M, Morisaki JH, Toy K, Shah IM, Kim J, Park S, Xu M, Basuino L, Chan L, Zeitschel D, Chambers HF, Tan MW, Brown EJ, Diep BA, Hazenbos WL. PMID: 24286981.
    View in: PubMed Mentions: 57 Fields:
    Translation:HumansAnimalsCells
  24. Epidemiologic Similarities in Pediatric Community-Associated Methicillin-Resistant and Methicillin-Sensitive Staphylococcus aureus in the San Francisco Bay Area. J Pediatric Infect Dis Soc. 2012 Sep; 1(3):200-11. Hsiang MS, Shiau R, Nadle J, Chan L, Lee B, Chambers HF, Pan E. PMID: 23687577; PMCID: PMC3656541.
    View in: PubMed Mentions: 10 Fields:
  25. Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury. Proc Natl Acad Sci U S A. 2010 Mar 23; 107(12):5587-92. Diep BA, Chan L, Tattevin P, Kajikawa O, Martin TR, Basuino L, Mai TT, Marbach H, Braughton KR, Whitney AR, Gardner DJ, Fan X, Tseng CW, Liu GY, Badiou C, Etienne J, Lina G, Matthay MA, DeLeo FR, Chambers HF. PMID: 20231457; PMCID: PMC2851770.
    View in: PubMed Mentions: 199 Fields:
    Translation:HumansAnimalsCells
  26. DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation. J Clin Invest. 2010 Mar; 120(3):756-67. Koliwad SK, Streeper RS, Monetti M, Cornelissen I, Chan L, Terayama K, Naylor S, Rao M, Hubbard B, Farese RV. PMID: 20124729; PMCID: PMC2827941.
    View in: PubMed Mentions: 123 Fields:
    Translation:AnimalsCells
  27. Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: evidence for independent chemokine functions in atherogenesis. Circulation. 2008 Apr 01; 117(13):1642-8. Saederup N, Chan L, Lira SA, Charo IF. PMID: 18165355; PMCID: PMC3589525.
    View in: PubMed Mentions: 99 Fields:
    Translation:AnimalsCells
  28. LPA3 receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA). J Leukoc Biol. 2007 Nov; 82(5):1193-200. Chan LC, Peters W, Xu Y, Chun J, Farese RV, Cases S. PMID: 17709403.
    View in: PubMed Mentions: 48 Fields:
    Translation:HumansAnimalsCells

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

Start with: newest oldestInclude: line numbers double spacing all authors publication IDs