Benjamin Gastfriend • UCSD Profiles (original) (raw)

  1. Development of the blood-brain barrier. Development. 2026 Jan 15; 153(2). Gastfriend BD, Daneman R. PMID: 41574630; PMCID: PMC12863308.
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    Translation:HumansAnimalsCells
  2. Identification of Variable Lymphocyte Receptors That Target the Human Blood-Brain Barrier. Pharmaceutics. 2025 Sep 10; 17(9). Katt ME, Waters EA, Gastfriend BD, Herrin BR, Cooper MD, Shusta EV. PMID: 41012515; PMCID: PMC12473985.
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  3. Regional heterogeneity of the blood-brain barrier. Nat Commun. 2025 Aug 08; 16(1):7332. Blanchette M, Bajc K, Gastfriend BD, Profaci CP, Ruderisch N, Dorrier CE, Zhong G, Cuevas-Diaz Duran R, Harvey SS, Garcia-Pak IH, Pintaric L, Leclerc M, Reveret L, Émond V, Wang A, Pant D, Tsai LT, Calon F, Isoherranen N, Palecek SP, Shusta EV, Wu J, Daneman R. PMID: 40781224; PMCID: PMC12334574.
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    Translation:AnimalsCells
  4. 3D organoids containing endothelial and neural cells generation by serial inductions of differentiation on human iPSC-derived embryoid bodies. bioRxiv. 2025 May 21. Wang T, Bagnell A, McDonald V, Gastfriend BD, Steiner JP, Elkahloun AG, Johnson K, Langston RG, Cookson MR, Nath A. PMID: 40475416; PMCID: PMC12139883.
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  5. Transcriptional Responses of In Vitro Blood-Brain Barrier Models to Shear Stress. Biomolecules. 2025 Jan 29; 15(2). Foreman KL, Gastfriend BD, Katt ME, Palecek SP, Shusta EV. PMID: 40001496; PMCID: PMC11853657.
    View in: PubMed Mentions: 1 Fields:
    Translation:HumansAnimalsCells
  6. Derivation of a Human Brain Organoid with Microglia Development. J Vis Exp. 2025 01 17; (215). Wang T, Gastfriend BD, McDonald V, Steiner JP, Elkahloun AG, Nath A. PMID: 39895643.
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    Translation:HumansCells
  7. Pericytes Enrich the Basement Membrane and Reduce Neutrophil Transmigration in an In Vitro Model of Peripheral Inflammation at the Blood-Brain Barrier. Biomater Res. 2024; 28:0081. McCloskey MC, Ahmad SD, Widom LP, Kasap P, Gastfriend BD, Shusta EV, Palecek SP, Engelhardt B, Gaborski TR, Flax J, Waugh RE, McGrath JL. PMID: 39363889; PMCID: PMC11447289.
    View in: PubMed Mentions: 7
  8. Notch3 directs differentiation of brain mural cells from human pluripotent stem cell-derived neural crest. Sci Adv. 2024 02 02; 10(5):eadi1737. Gastfriend BD, Snyder ME, Holt HE, Daneman R, Palecek SP, Shusta EV. PMID: 38306433; PMCID: PMC10836734.
    View in: PubMed Mentions: 8 Fields:
    Translation:HumansCells
  9. Dural mural cells paint an anti-inflammatory picture. J Exp Med. 2024 Feb 05; 221(2). Lummis NC, Gastfriend BD, Daneman R. PMID: 38270593; PMCID: PMC10818063.
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    Translation:Humans
  10. Intrinsic blood-brain barrier dysfunction contributes to multiple sclerosis pathogenesis. Brain. 2022 12 19; 145(12):4334-4348. Nishihara H, Perriot S, Gastfriend BD, Steinfort M, Cibien C, Soldati S, Matsuo K, Guimbal S, Mathias A, Palecek SP, Shusta EV, Pasquier RD, Engelhardt B. PMID: 35085379; PMCID: PMC10200307.
    View in: PubMed Mentions: 60 Fields:
    Translation:HumansCells
  11. Antibody-Targeted Liposomes for Enhanced Targeting of the Blood-Brain Barrier. Pharm Res. 2022 Jul; 39(7):1523-1534. Ye Z, Gastfriend BD, Umlauf BJ, Lynn DM, Shusta EV. PMID: 35169958; PMCID: PMC9250590.
    View in: PubMed Mentions: 13 Fields:
    Translation:HumansAnimals
  12. Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells. Elife. 2021 11 10; 10. Gastfriend BD, Nishihara H, Canfield SG, Foreman KL, Engelhardt B, Palecek SP, Shusta EV. PMID: 34755601; PMCID: PMC8664294.
    View in: PubMed Mentions: 40 Fields:
    Translation:HumansCells
  13. A human three-dimensional neural-perivascular 'assembloid' promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology. Nat Med. 2021 09; 27(9):1600-1606. Wang L, Sievert D, Clark AE, Lee S, Federman H, Gastfriend BD, Shusta EV, Palecek SP, Carlin AF, Gleeson JG. PMID: 34244682; PMCID: PMC8601037.
    View in: PubMed Mentions: 90 Fields:
    Translation:HumansCells
  14. Differentiation of human pluripotent stem cells to brain microvascular endothelial cell-like cells suitable to study immune cell interactions. STAR Protoc. 2021 06 18; 2(2):100563. Nishihara H, Gastfriend BD, Kasap P, Palecek SP, Shusta EV, Engelhardt B. PMID: 34151293; PMCID: PMC8188617.
    View in: PubMed Mentions: 22 Fields:
    Translation:HumansCells
  15. Integrative analysis of the human brain mural cell transcriptome. J Cereb Blood Flow Metab. 2021 11; 41(11):3052-3068. Gastfriend BD, Foreman KL, Katt ME, Palecek SP, Shusta EV. PMID: 34027687; PMCID: PMC8756477.
    View in: PubMed Mentions: 17 Fields:
    Translation:HumansAnimalsCells
  16. Differentiation of Brain Pericyte-Like Cells from Human Pluripotent Stem Cell-Derived Neural Crest. Curr Protoc. 2021 Jan; 1(1):e21. Gastfriend BD, Stebbins MJ, Du F, Shusta EV, Palecek SP. PMID: 33484491; PMCID: PMC7839246.
    View in: PubMed Mentions: 14 Fields:
    Translation:HumansCells
  17. Advancing human induced pluripotent stem cell-derived blood-brain barrier models for studying immune cell interactions. FASEB J. 2020 12; 34(12):16693-16715. Nishihara H, Gastfriend BD, Soldati S, Perriot S, Mathias A, Sano Y, Shimizu F, Gosselet F, Kanda T, Palecek SP, Du Pasquier R, Shusta EV, Engelhardt B. PMID: 33124083; PMCID: PMC7686106.
    View in: PubMed Mentions: 56 Fields:
    Translation:HumansCells
  18. Adaptable pulsatile flow generated from stem cell-derived cardiomyocytes using quantitative imaging-based signal transduction. Lab Chip. 2020 10 21; 20(20):3744-3756. Qian T, Gil DA, Contreras Guzman E, Gastfriend BD, Tweed KE, Palecek SP, Skala MC. PMID: 33048070; PMCID: PMC7699819.
    View in: PubMed Mentions: 3 Fields:
    Translation:HumansCells
  19. Immobilized metal affinity chromatography optimization for poly-histidine tagged proteins. J Chromatogr A. 2020 Oct 11; 1629:461505. Riguero V, Clifford R, Dawley M, Dickson M, Gastfriend B, Thompson C, Wang SC, O'Connor E. PMID: 32861092.
    View in: PubMed Mentions: 16 Fields:
    Translation:HumansAnimalsCells
  20. Antibody screening using a human iPSC-based blood-brain barrier model identifies antibodies that accumulate in the CNS. FASEB J. 2020 09; 34(9):12549-12564. Georgieva JV, Goulatis LI, Stutz CC, Canfield SG, Song HW, Gastfriend BD, Shusta EV. PMID: 32960493; PMCID: PMC7513543.
    View in: PubMed Mentions: 20 Fields:
    Translation:HumansAnimalsCells
  21. Transcriptomic comparison of human and mouse brain microvessels. Sci Rep. 2020 07 23; 10(1):12358. Song HW, Foreman KL, Gastfriend BD, Kuo JS, Palecek SP, Shusta EV. PMID: 32704093; PMCID: PMC7378255.
    View in: PubMed Mentions: 85 Fields:
    Translation:HumansAnimalsCells
  22. Streptococcus agalactiae disrupts P-glycoprotein function in brain endothelial cells. Fluids Barriers CNS. 2019 Aug 22; 16(1):26. Kim BJ, McDonagh MA, Deng L, Gastfriend BD, Schubert-Unkmeir A, Doran KS, Shusta EV. PMID: 31434575; PMCID: PMC6704684.
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    Translation:HumansAnimalsCells
  23. An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons. Fluids Barriers CNS. 2019 Aug 07; 16(1):25. Canfield SG, Stebbins MJ, Faubion MG, Gastfriend BD, Palecek SP, Shusta EV. PMID: 31387594; PMCID: PMC6685239.
    View in: PubMed Mentions: 53 Fields:
    Translation:HumansAnimalsCells
  24. Human pluripotent stem cell-derived brain pericyte-like cells induce blood-brain barrier properties. Sci Adv. 2019 03; 5(3):eaau7375. Stebbins MJ, Gastfriend BD, Canfield SG, Lee MS, Richards D, Faubion MG, Li WJ, Daneman R, Palecek SP, Shusta EV. PMID: 30891496; PMCID: PMC6415958.
    View in: PubMed Mentions: 118 Fields:
    Translation:HumansAnimalsCells
  25. Preventing S. aureus biofilm formation on titanium surfaces by the release of antimicrobial β-peptides from polyelectrolyte multilayers. Acta Biomater. 2019 07 15; 93:50-62. Rodríguez López AL, Lee MR, Ortiz BJ, Gastfriend BD, Whitehead R, Lynn DM, Palecek SP. PMID: 30831325; PMCID: PMC6693497.
    View in: PubMed Mentions: 14 Fields:
    Translation:AnimalsCells
  26. Modeling the blood-brain barrier: Beyond the endothelial cells. Curr Opin Biomed Eng. 2018 Mar; 5:6-12. Gastfriend BD, Palecek SP, Shusta EV. PMID: 29915815; PMCID: PMC6003712.
    View in: PubMed Mentions: 75

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

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