Hiromi Wettersten • UCSD Profiles (original) (raw)
- Macrophage-Engaging IgG4 Antibody Triggers Cytotoxicity against Integrin αvβ3+ Cancers. Mol Cancer Ther. 2026 Mar 02; 25(3):448-456. Reddy JP, Yu Z, Shepard RM, Von Schalscha T, Clague RA, Peixoto BP, McCormack SJ, Onaitis MW, Weis SM, Cheresh DA, Wettersten HI. PMID: 41081633; PMCID: PMC12570272.
View in: PubMed Mentions: - Lung Cancer Cells Secrete Glutamine to Accumulate Tumor-Associated Macrophages. Mol Carcinog. 2026 Mar; 65(3):356-364. Reddy JP, Clague RA, Peixoto BP, Bernstein S, Lauth EE, Takanohashi CY, Kim SC, Wettersten HI. PMID: 41498201; PMCID: PMC12799098.
View in: PubMed Mentions: Fields:
Translation:HumansAnimalsCells - A STAT3/integrin axis accelerates pancreatic cancer initiation and progression. Cell Rep. 2025 Aug 26; 44(8):116010. Campos AD, Shepard RM, Ortega Z, Heumann I, Wilke AE, Nam A, Cable C, Kouhmareh K, Klemke R, Mattson NM, Ideker T, De Arruda Saldanha C, Heinz S, Weaver V, Von Schalscha T, Wettersten HI, Weis SM, Cheresh DA. PMID: 40701148; PMCID: PMC12445075.
View in: PubMed Mentions: 2 Fields:
Translation:HumansAnimalsCells - The Emerging Roles of Metabolic Reprogramming in Non-Small Cell Lung Cancer Progression. Front Biosci (Landmark Ed). 2025 Jul 08; 30(7):31363. Peixoto BP, Clague RA, Reddy JP, Wettersten HI. PMID: 40765333.
View in: PubMed Mentions: 1 Fields:
Translation:HumansAnimals - Targeting Pancreatic Cancer Cell Stemness by Blocking Fibronectin-Binding Integrins on Cancer-Associated Fibroblasts. Cancer Res Commun. 2025 01 01; 5(1):195-208. Wu C, Von Schalscha T, Sansanwal D, Qian C, Jiang Q, Shepard RM, Wettersten HI, McCormack SJ, Weis SM, Cheresh DA. PMID: 39785683; PMCID: PMC11783622.
View in: PubMed Mentions: 1 Fields:
Translation:HumansAnimalsCells - Integrin αvβ3 Upregulation in Response to Nutrient Stress Promotes Lung Cancer Cell Metabolic Plasticity. Cancer Res. 2024 May 15; 84(10):1630-1642. Nam A, Jain S, Wu C, Campos A, Shepard RM, Yu Z, Reddy JP, Von Schalscha T, Weis SM, Onaitis M, Wettersten HI, Cheresh DA. PMID: 38588407; PMCID: PMC11096068.
View in: PubMed Mentions: 8 Fields:
Translation:HumansAnimalsCells - Pancreatic cancer cells upregulate LPAR4 in response to isolation stress to promote an ECM-enriched niche and support tumour initiation. Nat Cell Biol. 2023 02; 25(2):309-322. Wu C, Rakhshandehroo T, Wettersten HI, Campos A, von Schalscha T, Jain S, Yu Z, Tan J, Mose E, Childers BG, Lowy AM, Weis SM, Cheresh DA. PMID: 36646789; PMCID: PMC10280815.
View in: PubMed Mentions: 19 Fields:
Translation:HumansCells - Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis. Cell Stem Cell. 2020 02 06; 26(2):187-204.e10. Zhu Z, Mesci P, Bernatchez JA, Gimple RC, Wang X, Schafer ST, Wettersten HI, Beck S, Clark AE, Wu Q, Prager BC, Kim LJY, Dhanwani R, Sharma S, Garancher A, Weis SM, Mack SC, Negraes PD, Trujillo CA, Penalva LO, Feng J, Lan Z, Zhang R, Wessel AW, Dhawan S, Diamond MS, Chen CC, Wechsler-Reya RJ, Gage FH, Hu H, Siqueira-Neto JL, Muotri AR, Cheresh DA, Rich JN. PMID: 31956038; PMCID: PMC9628766.
View in: PubMed Mentions: 120 Fields:
Translation:HumansCells - Reprogramming of Metabolism in Kidney Cancer. Semin Nephrol. 2020 01; 40(1):2-13. Wettersten HI. PMID: 32130963.
View in: PubMed Mentions: 26 Fields:
Translation:HumansCells - Arming Tumor-Associated Macrophages to Reverse Epithelial Cancer Progression. Cancer Res. 2019 10 01; 79(19):5048-5059. Wettersten HI, Weis SM, Pathria P, Von Schalscha T, Minami T, Varner JA, Cheresh DA. PMID: 31416839; PMCID: PMC6774806.
View in: PubMed Mentions: 19 Fields:
Translation:HumansAnimalsCells - XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies. Oncotarget. 2018 Oct 02; 9(77):34567-34581. Baek HB, Lombard AP, Libertini SJ, Fernandez-Rubio A, Vinall R, Gandour-Edwards R, Nakagawa R, Vidallo K, Nishida K, Siddiqui S, Wettersten H, Landesman Y, Weiss RH, Ghosh PM, Mudryj M. PMID: 30349650; PMCID: PMC6195388.
View in: PubMed Mentions: 16 Fields: - Proapoptotic PUMA targets stem-like breast cancer cells to suppress metastasis. J Clin Invest. 2018 01 02; 128(1):531-544. Sun Q, Lesperance J, Wettersten H, Luterstein E, DeRose YS, Welm A, Cheresh DA, Desgrosellier JS. PMID: 29227280; PMCID: PMC5749527.
View in: PubMed Mentions: 31 Fields:
Translation:HumansAnimalsCells - Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers. Cancer Discov. 2017 12; 7(12):1464-1479. Seguin L, Camargo MF, Wettersten HI, Kato S, Desgrosellier JS, von Schalscha T, Elliott KC, Cosset E, Lesperance J, Weis SM, Cheresh DA. PMID: 28893801; PMCID: PMC5718959.
View in: PubMed Mentions: 64 Fields:
Translation:HumansAnimalsCells - Metabolic reprogramming in clear cell renal cell carcinoma. Nat Rev Nephrol. 2017 07; 13(7):410-419. Wettersten HI, Aboud OA, Lara PN, Weiss RH. PMID: 28480903.
View in: PubMed Mentions: 343 Fields:
Translation:Humans - Inhibiting tryptophan metabolism enhances interferon therapy in kidney cancer. Oncotarget. 2016 10 11; 7(41):66540-66557. Trott JF, Kim J, Abu Aboud O, Wettersten H, Stewart B, Berryhill G, Uzal F, Hovey RC, Chen CH, Anderson K, Graef A, Sarver AL, Modiano JF, Weiss RH. PMID: 27572319; PMCID: PMC5341819.
View in: PubMed Mentions: 36 Fields:
Translation:HumansAnimalsCells - Grade-Dependent Metabolic Reprogramming in Kidney Cancer Revealed by Combined Proteomics and Metabolomics Analysis. Cancer Res. 2015 Jun 15; 75(12):2541-52. Wettersten HI, Hakimi AA, Morin D, Bianchi C, Johnstone ME, Donohoe DR, Trott JF, Aboud OA, Stirdivant S, Neri B, Wolfert R, Stewart B, Perego R, Hsieh JJ, Weiss RH. PMID: 25952651; PMCID: PMC4470795.
View in: PubMed Mentions: 174 Fields:
Translation:HumansCells - Specific inhibition of the nuclear exporter exportin-1 attenuates kidney cancer growth. PLoS One. 2014; 9(12):e113867. Wettersten HI, Landesman Y, Friedlander S, Shacham S, Kauffman M, Weiss RH. PMID: 25461627; PMCID: PMC4252068.
View in: PubMed Mentions: 18 Fields:
Translation:HumansAnimalsCells - Biological evaluation of a novel sorafenib analogue, t-CUPM. Cancer Chemother Pharmacol. 2015 Jan; 75(1):161-71. Wecksler AT, Hwang SH, Liu JY, Wettersten HI, Morisseau C, Wu J, Weiss RH, Hammock BD. PMID: 25413440; PMCID: PMC4400119.
View in: PubMed Mentions: 6 Fields:
Translation:HumansAnimalsCells - Novel inhibitors of nuclear transport cause cell cycle arrest and decrease cyst growth in ADPKD associated with decreased CDK4 levels. Am J Physiol Renal Physiol. 2014 Dec 01; 307(11):F1179-86. Tan M, Wettersten HI, Chu K, Huso DL, Watnick T, Friedlander S, Landesman Y, Weiss RH. PMID: 25234309; PMCID: PMC4254973.
View in: PubMed Mentions: 8 Fields:
Translation:HumansAnimalsCells - Dual inhibition of cyclooxygenase-2 and soluble epoxide hydrolase synergistically suppresses primary tumor growth and metastasis. Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30):11127-32. Zhang G, Panigrahy D, Hwang SH, Yang J, Mahakian LM, Wettersten HI, Liu JY, Wang Y, Ingham ES, Tam S, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. PMID: 25024195; PMCID: PMC4121808.
View in: PubMed Mentions: 69 Fields:
Translation:Animals - Synergistic tumor suppression by combined inhibition of telomerase and CDKN1A. Proc Natl Acad Sci U S A. 2014 Jul 29; 111(30):E3062-71. Gupta R, Dong Y, Solomon PD, Wettersten HI, Cheng CJ, Min JN, Henson J, Dogra SK, Hwang SH, Hammock BD, Zhu LJ, Reddel RR, Saltzman WM, Weiss RH, Chang S, Green MR, Wajapeyee N. PMID: 25024194; PMCID: PMC4121806.
View in: PubMed Mentions: 21 Fields:
Translation:HumansAnimalsCells - Novel sorafenib-based structural analogues: in-vitro anticancer evaluation of t-MTUCB and t-AUCMB. Anticancer Drugs. 2014 Apr; 25(4):433-46. Wecksler AT, Hwang SH, Wettersten HI, Gilda JE, Patton A, Leon LJ, Carraway KL, Gomes AV, Baar K, Weiss RH, Hammock BD. PMID: 24525589; PMCID: PMC3947856.
View in: PubMed Mentions: 2 Fields:
Translation:HumansCells - Mealtime, temporal, and daily variability of the human urinary and plasma metabolomes in a tightly controlled environment. PLoS One. 2014; 9(1):e86223. Kim K, Mall C, Taylor SL, Hitchcock S, Zhang C, Wettersten HI, Jones AD, Chapman A, Weiss RH. PMID: 24475090; PMCID: PMC3901684.
View in: PubMed Mentions: 47 Fields:
Translation:Humans - Metabolomic profiling of tumor-bearing mice. Methods Enzymol. 2014; 543:275-96. Wettersten HI, Ganti S, Weiss RH. PMID: 24924138.
View in: PubMed Mentions: 4 Fields:
Translation:Animals - Anti-inflammatory effects of ω-3 polyunsaturated fatty acids and soluble epoxide hydrolase inhibitors in angiotensin-II-dependent hypertension. J Cardiovasc Pharmacol. 2013 Sep; 62(3):285-97. Ulu A, Harris TR, Morisseau C, Miyabe C, Inoue H, Schuster G, Dong H, Iosif AM, Liu JY, Weiss RH, Chiamvimonvat N, Imig JD, Hammock BD. PMID: 23676336; PMCID: PMC3773051.
View in: PubMed Mentions: 68 Fields:
Translation:AnimalsCells - Inhibition of PPARα induces cell cycle arrest and apoptosis, and synergizes with glycolysis inhibition in kidney cancer cells. PLoS One. 2013; 8(8):e71115. Abu Aboud O, Wettersten HI, Weiss RH. PMID: 23951092; PMCID: PMC3737191.
View in: PubMed Mentions: 47 Fields:
Translation:HumansCells - Small-molecule inhibitors of p21 as novel therapeutics for chemotherapy-resistant kidney cancer. Future Med Chem. 2013 Jun; 5(9):991-4. Liu R, Wettersten HI, Park SH, Weiss RH. PMID: 23734682; PMCID: PMC4573579.
View in: PubMed Mentions: 19 Fields:
Translation:Humans - Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proc Natl Acad Sci U S A. 2013 Apr 16; 110(16):6530-5. Zhang G, Panigrahy D, Mahakian LM, Yang J, Liu JY, Stephen Lee KS, Wettersten HI, Ulu A, Hu X, Tam S, Hwang SH, Ingham ES, Kieran MW, Weiss RH, Ferrara KW, Hammock BD. PMID: 23553837; PMCID: PMC3631682.
View in: PubMed Mentions: 152 Fields:
Translation:HumansAnimalsCells - Potential biofluid markers and treatment targets for renal cell carcinoma. Nat Rev Urol. 2013 Jun; 10(6):336-44. Wettersten HI, Weiss RH. PMID: 23545813.
View in: PubMed Mentions: 14 Fields:
Translation:HumansAnimals - From bead to flask: Synthesis of a complex β-amido-amide for probe-development studies. Beilstein J Org Chem. 2013; 9:260-4. Martin KS, Soldi C, Candee KN, Wettersten HI, Weiss RH, Shaw JT. PMID: 23400429; PMCID: PMC3566855.
View in: PubMed Mentions: - A novel p21 attenuator which is structurally related to sorafenib. Cancer Biol Ther. 2013 Mar; 14(3):278-85. Wettersten HI, Hee Hwang S, Li C, Shiu EY, Wecksler AT, Hammock BD, Weiss RH. PMID: 23298903; PMCID: PMC3595311.
View in: PubMed Mentions: 35 Fields:
Translation:HumansCells - Applications of metabolomics for kidney disease research: from biomarkers to therapeutic targets. Organogenesis. 2013 Jan-Mar; 9(1):11-8. Wettersten HI, Weiss RH. PMID: 23538740; PMCID: PMC3674034.
View in: PubMed Mentions: 13 Fields:
Translation:Humans - CRM1 blockade by selective inhibitors of nuclear export attenuates kidney cancer growth. J Urol. 2013 Jun; 189(6):2317-26. Inoue H, Kauffman M, Shacham S, Landesman Y, Yang J, Evans CP, Weiss RH. PMID: 23079374; PMCID: PMC4593314.
View in: PubMed Mentions: 65 Fields:
Translation:HumansAnimalsCells - Sorafenib attenuates p21 in kidney cancer cells and augments cell death in combination with DNA-damaging chemotherapy. Cancer Biol Ther. 2011 Nov 01; 12(9):827-36. Inoue H, Hwang SH, Wecksler AT, Hammock BD, Weiss RH. PMID: 21878748; PMCID: PMC3225758.
View in: PubMed Mentions: 43 Fields:
Translation:HumansCells
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
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