Yusu Gu • UCSD Profiles (original) (raw)
- Transcriptional readthrough at Atf4 locus suppresses Rps19bp1 and impairs heart development. Cardiovasc Res. 2026 Feb 14; 121(18):2909-2921. Zhang Z, Wu T, Chen Z, Chen D, Liang Z, Adams C, Gu Y, Ye M, Barroga F, Evans S, Zhou X, Chen J. PMID: 41248983; PMCID: PMC13012809.
View in: PubMed Mentions: - Connexin-43 Restoration Alleviates Desmosomal Arrhythmogenic Cardiomyopathy. Circ Heart Fail. 2026 Apr; 19(4):e013801. Zhang J, Zanella F, Ellis MW, Bradford WH, Gutierrez-Lara EJ, Wang TM, Fujita K, Duron C, Karakikes I, Lyon RC, Mezzano V, Roberts JD, Carromeu C, Gu Y, Martin JL, Muotri AR, Scheinman MM, Peterson KL, Sheikh F. PMID: 41582809; PMCID: PMC12885159.
View in: PubMed Mentions: Fields: - AAV-TNNI3 rescues an experimental murine Tnni3 mutation resulting in thin filament mediated DCM. J Mol Cell Cardiol. 2026 Mar; 212:26-37. Bushway PJ, Feng W, Cruz MSM, Maisel S, Shathaya A, Rao P, Patel U, Park J, Chen C, Tang Z, Gunes B, Gunes E, Ye M, Gu Y, Adler E. PMID: 41494578.
View in: PubMed Mentions: Fields:
Translation:HumansAnimalsCells - Transcription regulation by TBX18 in smooth muscle cells is essential for normal aortic development and homeostasis. Cardiovasc Res. 2025 Dec 09; 121(15):2419-2431. Mukherjee D, Larcher V, Winter H, Sachs N, Andriani F, Chiesa M, Perrucci GL, Rega S, Günther S, Kuenne C, Martin JC, Gu Y, Pelisek J, Fischer A, Peruzzo S, Pizzo E, Peterson KL, Dimmeler S, Maegdefessel L, Cattaneo P, Evans SM, Guimarães-Camboa N. PMID: 41263385; PMCID: PMC12687880.
View in: PubMed Mentions: Fields:
Translation:HumansAnimalsCells - A Novel miniALPK3 Gene Therapy for ALPK3-Associated Cardiomyopathy. Circulation. 2025 Nov 18; 152(20):1453-1455. Feng W, Bogomolovas J, Shain AG, Wang L, Chen C, Ye M, Gu Y, Zhou X, Chen J. PMID: 41248220; PMCID: PMC12626394.
View in: PubMed Mentions: 1 Fields: - Human Variant in the Cardiac Troponin I Switch Domain Causes Diastolic Dysfunction in a Novel Mouse Model. J Am Heart Assoc. 2025 Nov 18; 14(22):e040852. Silver E, Duran JM, Gunes BB, Fenwick AJ, Maisel S, Wang TM, Manso AM, Cruz MS, Gu Y, Fong J, Shathaya A, Chen C, Soto-Hermida A, Feng W, Cho Y, Bogomolovas J, Gelow JM, Masri A, Frazer KA, Ross RS, Chen J, Makarewich CA, Cammarato A, McCulloch AD, Bushway P, Adler ED. PMID: 41195779; PMCID: PMC12887218.
View in: PubMed Mentions: Fields: - RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing. Circ Res. 2025 Sep 12; 137(7):1027-1044. Wu T, Chen Z, Gao C, Stanley EV, Zhang Z, Gu Y, Zhou X, Chen J. PMID: 40859824; PMCID: PMC12744351.
View in: PubMed Mentions: Fields:
Translation:AnimalsCells - Overlapping functions between Lamp2a and Lamp2b in cardiac autophagy. Autophagy. 2025 Sep; 21(9):2046-2057. Sampaio Cruz M, Manso AM, Soto-Hermida A, Bushway P, Silver E, Gunes BB, Tang Z, Gonzalez G, Lau S, Arbayo J, Najor RH, Chi L, Gu Y, Feng W, Cowling RT, Gustafsson AB, Chen J, Adler ED. PMID: 40202173; PMCID: PMC12366817.
View in: PubMed Mentions: 1 Fields:
Translation:AnimalsCells - α Protein Kinase 3 Is Essential for Neonatal and Adult Cardiac Function. J Am Heart Assoc. 2025 Apr; 14(7):e039464. Feng W, Wang L, Bogomolovas J, Zhang Z, Huang T, Chang CW, Shain A, Gu Y, Cho Y, Zhou X, Chen J. PMID: 40135575; PMCID: PMC12132735.
View in: PubMed Mentions: Fields:
Translation:HumansAnimalsCells - Combined Loss of Obsc and Obsl1 in Murine Hearts Results in Diastolic Dysfunction, Altered Metabolism, and Deregulated Mitophagy. Circ Heart Fail. 2025 Apr; 18(4):e011867. Fujita K, Desmond P, Blondelle J, Soták M, Rajan MR, Clark M, Estève É, Chan Y, Gu Y, Actis Dato V, Marrocco V, Dalton ND, Ghassemian M, Do A, Klos M, Peterson KL, Sheikh F, Cho Y, Börgeson E, Lange S. PMID: 40066567; PMCID: PMC11995854.
View in: PubMed Mentions: 3 Fields:
Translation:AnimalsCells - Loss of GATAD1 in cardiomyocyte does not cause cardiomyopathy in mice. J Mol Histol. 2024 Dec 06; 56(1):33. Pang J, Zhu S, Shyy M, Duong J, Tran T, Sanchez-Garcia E, Chen C, Gu Y, Fang X. PMID: 39641830; PMCID: PMC12054008.
View in: PubMed Mentions: Fields:
Translation:AnimalsCells - Dietary linoleic acid supplementation fails to rescue established cardiomyopathy in Barth syndrome. J Mol Cell Cardiol Plus. 2024 Jun; 8. Zhu S, Pang J, Nguyen A, Huynh H, Lee S, Gu Y, Vaz FM, Fang X. PMID: 38974772; PMCID: PMC11225933.
View in: PubMed Mentions: 1 - Temporal Effects of Safflower Oil Diet-Based Linoleic Acid Supplementation on Barth Syndrome Cardiomyopathy. Circulation. 2024 03 05; 149(10):790-793. Zhu S, Pang J, Nguyen A, Tan C, Tso A, Huynh T, Gu Y, Gustafsson AB, Vaz FM, Evans SM, Fang X. PMID: 38437482; PMCID: PMC10914323.
View in: PubMed Mentions: 2 Fields:
Translation:Humans - Plakophilin 2 gene therapy prevents and rescues arrhythmogenic right ventricular cardiomyopathy in a mouse model harboring patient genetics. Nat Cardiovasc Res. 2023 12; 2(12):1246-1261. Bradford WH, Zhang J, Gutierrez-Lara EJ, Liang Y, Do A, Wang TM, Nguyen L, Mataraarachchi N, Wang J, Gu Y, McCulloch A, Peterson KL, Sheikh F. PMID: 39196150; PMCID: PMC11357983.
View in: PubMed Mentions: 30 Fields:
Translation:HumansAnimalsCells - Interaction of Filamin C With Actin Is Essential for Cardiac Development and Function. Circ Res. 2023 08 18; 133(5):400-411. Zhou X, Fang X, Ithychanda SS, Wu T, Gu Y, Chen C, Wang L, Bogomolovas J, Qin J, Chen J. PMID: 37492967; PMCID: PMC10529502.
View in: PubMed Mentions: 11 Fields:
Translation:AnimalsCells - Increasing Mononuclear Diploid Cardiomyocytes by Loss of E2F Transcription Factor 7/8 Fails to Improve Cardiac Regeneration After Infarct. Circulation. 2023 01 10; 147(2):183-186. Yu Z, Zhang L, Cattaneo P, Guimarães-Camboa N, Fang X, Gu Y, Peterson KL, Bogomolovas J, Cuitino C, Leone GW, Chen J, Evans SM. PMID: 36622904; PMCID: PMC9988404.
View in: PubMed Mentions: 5 Fields:
Translation:HumansCells - DELE1 is protective for mitochondrial cardiomyopathy. J Mol Cell Cardiol. 2023 02; 175:44-48. Huynh H, Zhu S, Lee S, Bao Y, Pang J, Nguyen A, Gu Y, Chen C, Ouyang K, Evans SM, Fang X. PMID: 36539111; PMCID: PMC10387237.
View in: PubMed Mentions: 10 Fields:
Translation:HumansCells - Mitochondrial Stress Induces an HRI-eIF2α Pathway Protective for Cardiomyopathy. Circulation. 2022 09 27; 146(13):1028-1031. Zhu S, Nguyen A, Pang J, Zhao J, Chen Z, Liang Z, Gu Y, Huynh H, Bao Y, Lee S, Kluger Y, Ouyang K, Evans SM, Fang X. PMID: 36154620; PMCID: PMC9523491.
View in: PubMed Mentions: 12 Fields:
Translation:HumansCells - PRDM16 Is a Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle. Circulation. 2022 02 22; 145(8):586-602. Wu T, Liang Z, Zhang Z, Liu C, Zhang L, Gu Y, Peterson KL, Evans SM, Fu XD, Chen J. PMID: 34915728; PMCID: PMC8860879.
View in: PubMed Mentions: 48 Fields:
Translation:AnimalsCells - Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network. PLoS Genet. 2021 09; 17(9):e1009785. Tan C, Zhu S, Chen Z, Liu C, Li YE, Zhu M, Zhang Z, Zhang Z, Zhang L, Gu Y, Liang Z, Boyer TG, Ouyang K, Evans SM, Fang X. PMID: 34506481; PMCID: PMC8432849.
View in: PubMed Mentions: 8 Fields:
Translation:AnimalsCells - Constitutive protein kinase G activation exacerbates stress-induced cardiomyopathy. Br J Pharmacol. 2022 06; 179(11):2413-2429. Schwaerzer GK, Casteel DE, Cividini F, Kalyanaraman H, Zhuang S, Gu Y, Dalton ND, Peterson KL, Dillmann WH, Boss GR, Pilz RB. PMID: 34000062; PMCID: PMC9926932.
View in: PubMed Mentions: 5 Fields:
Translation:AnimalsCells - Cardiolipin Remodeling Defects Impair Mitochondrial Architecture and Function in a Murine Model of Barth Syndrome Cardiomyopathy. Circ Heart Fail. 2021 06; 14(6):e008289. Zhu S, Chen Z, Zhu M, Shen Y, Leon LJ, Chi L, Spinozzi S, Tan C, Gu Y, Nguyen A, Zhou Y, Feng W, Vaz FM, Wang X, Gustafsson AB, Evans SM, Kunfu O, Fang X. PMID: 34129362; PMCID: PMC8210459.
View in: PubMed Mentions: 34 Fields:
Translation:AnimalsCells - Desmosomal COP9 regulates proteome degradation in arrhythmogenic right ventricular dysplasia/cardiomyopathy. J Clin Invest. 2021 06 01; 131(11). Liang Y, Lyon RC, Pellman J, Bradford WH, Lange S, Bogomolovas J, Dalton ND, Gu Y, Bobar M, Lee MH, Iwakuma T, Nigam V, Asimaki A, Scheinman M, Peterson KL, Sheikh F. PMID: 33857019; PMCID: PMC8159691.
View in: PubMed Mentions: 15 Fields:
Translation:HumansAnimalsCells - Atypical ALPK2 kinase is not essential for cardiac development and function. Am J Physiol Heart Circ Physiol. 2020 06 01; 318(6):H1509-H1515. Bogomolovas J, Feng W, Yu MD, Huang S, Zhang L, Trexler C, Gu Y, Spinozzi S, Chen J. PMID: 32383995; PMCID: PMC7311700.
View in: PubMed Mentions: 7 Fields:
Translation:AnimalsCells - Cardiomyocyte Expression of ZO-1 Is Essential for Normal Atrioventricular Conduction but Does Not Alter Ventricular Function. Circ Res. 2020 07 03; 127(2):284-297. Zhang J, Vincent KP, Peter AK, Klos M, Cheng H, Huang SM, Towne JK, Ferng D, Gu Y, Dalton ND, Chan Y, Li R, Peterson KL, Chen J, McCulloch AD, Knowlton KU, Ross RS. PMID: 32345129; PMCID: PMC7571547.
View in: PubMed Mentions: 9 Fields:
Translation:AnimalsCells - Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog. Nat Commun. 2019 08 06; 10(1):3533. Schwaerzer GK, Kalyanaraman H, Casteel DE, Dalton ND, Gu Y, Lee S, Zhuang S, Wahwah N, Schilling JM, Patel HH, Zhang Q, Makino A, Milewicz DM, Peterson KL, Boss GR, Pilz RB. PMID: 31387997; PMCID: PMC6684604.
View in: PubMed Mentions: 20 Fields:
Translation:HumansAnimalsCells - Combinatorial interactions of genetic variants in human cardiomyopathy. Nat Biomed Eng. 2019 02; 3(2):147-157. Deacon DC, Happe CL, Chen C, Tedeschi N, Manso AM, Li T, Dalton ND, Peng Q, Farah EN, Gu Y, Tenerelli KP, Tran VD, Chen J, Peterson KL, Schork NJ, Adler ED, Engler AJ, Ross RS, Chi NC. PMID: 30923642; PMCID: PMC6433174.
View in: PubMed Mentions: 28 Fields:
Translation:HumansAnimalsCells - Reduction of myocardial ischaemia-reperfusion injury by inactivating oxidized phospholipids. Cardiovasc Res. 2019 01 01; 115(1):179-189. Yeang C, Hasanally D, Que X, Hung MY, Stamenkovic A, Chan D, Chaudhary R, Margulets V, Edel AL, Hoshijima M, Gu Y, Bradford W, Dalton N, Miu P, Cheung DY, Jassal DS, Pierce GN, Peterson KL, Kirshenbaum LA, Witztum JL, Tsimikas S, Ravandi A. PMID: 29850765; PMCID: PMC6302283.
View in: PubMed Mentions: 44 Fields:
Translation:AnimalsCells - A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure. Elife. 2018 12 06; 7. Pollak AJ, Liu C, Gudlur A, Mayfield JE, Dalton ND, Gu Y, Chen J, Heller Brown J, Hogan PG, Wiley SE, Peterson KL, Dixon JE. PMID: 30520731; PMCID: PMC6298778.
View in: PubMed Mentions: 19 Fields:
Translation:HumansAnimalsCells - Luma is not essential for murine cardiac development and function. Cardiovasc Res. 2018 Mar 01; 114(3):378-388. Stroud MJ, Fang X, Zhang J, Guimarães-Camboa N, Veevers J, Dalton ND, Gu Y, Bradford WH, Peterson KL, Evans SM, Gerace L, Chen J. PMID: 29040414; PMCID: PMC6019056.
View in: PubMed Mentions: 30 Fields:
Translation:HumansAnimalsCells - Infarct Fibroblasts Do Not Derive From Bone Marrow Lineages. Circ Res. 2018 02 16; 122(4):583-590. Moore-Morris T, Cattaneo P, Guimarães-Camboa N, Bogomolovas J, Cedenilla M, Banerjee I, Ricote M, Kisseleva T, Zhang L, Gu Y, Dalton ND, Peterson KL, Chen J, Pucéat M, Evans SM. PMID: 29269349; PMCID: PMC5815911.
View in: PubMed Mentions: 46 Fields:
Translation:AnimalsCells - Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy. J Clin Invest. 2017 Aug 01; 127(8):3189-3200. Fang X, Bogomolovas J, Wu T, Zhang W, Liu C, Veevers J, Stroud MJ, Zhang Z, Ma X, Mu Y, Lao DH, Dalton ND, Gu Y, Wang C, Wang M, Liang Y, Lange S, Ouyang K, Peterson KL, Evans SM, Chen J. PMID: 28737513; PMCID: PMC5531406.
View in: PubMed Mentions: 93 Fields:
Translation:AnimalsCells - Impaired mitophagy facilitates mitochondrial damage in Danon disease. J Mol Cell Cardiol. 2017 07; 108:86-94. Hashem SI, Murphy AN, Divakaruni AS, Klos ML, Nelson BC, Gault EC, Rowland TJ, Perry CN, Gu Y, Dalton ND, Bradford WH, Devaney EJ, Peterson KL, Jones KL, Taylor MRG, Chen J, Chi NC, Adler ED. PMID: 28526246.
View in: PubMed Mentions: 36 Fields:
Translation:HumansAnimalsCells - Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo. Cell Stem Cell. 2017 03 02; 20(3):345-359.e5. Guimarães-Camboa N, Cattaneo P, Sun Y, Moore-Morris T, Gu Y, Dalton ND, Rockenstein E, Masliah E, Peterson KL, Stallcup WB, Chen J, Evans SM. PMID: 28111199; PMCID: PMC5337131.
View in: PubMed Mentions: 256 Fields:
Translation:HumansCells - Increased Echogenicity and Radiodense Foci on Echocardiogram and MicroCT in Murine Myocarditis. PLoS One. 2016; 11(8):e0159971. Peter AK, Bradford WH, Dalton ND, Gu Y, Chao CJ, Peterson KL, Knowlton KU. PMID: 27486657; PMCID: PMC4972301.
View in: PubMed Mentions: 1 Fields:
Translation:HumansAnimalsCells - Desmosomal junctions are necessary for adult sinus node function. Cardiovasc Res. 2016 08 01; 111(3):274-86. Mezzano V, Liang Y, Wright AT, Lyon RC, Pfeiffer E, Song MY, Gu Y, Dalton ND, Scheinman M, Peterson KL, Evans SM, Fowler S, Cerrone M, McCulloch AD, Sheikh F. PMID: 27097650; PMCID: PMC4957488.
View in: PubMed Mentions: 21 Fields:
Translation:HumansAnimalsCells - Selective Life-Long Skeletal Myofiber-Targeted VEGF Gene Ablation Impairs Exercise Capacity in Adult Mice. J Cell Physiol. 2016 Feb; 231(2):505-11. Tang K, Gu Y, Dalton ND, Wagner H, Peterson KL, Wagner PD, Breen EC. PMID: 26201683.
View in: PubMed Mentions: 6 Fields:
Translation:AnimalsCells - Analysis and validation of traits associated with a single nucleotide polymorphism Gly364Ser in catestatin using humanized chromogranin A mouse models. J Hypertens. 2016 Jan; 34(1):68-78. Mir SA, Zhang K, Milic M, Gu Y, Rieg T, Ziegler M, Vaingankar SM. PMID: 26556564; PMCID: PMC5580682.
View in: PubMed Mentions: 6 Fields:
Translation:HumansAnimalsCells - Lmo7 is dispensable for skeletal muscle and cardiac function. Am J Physiol Cell Physiol. 2015 Oct 01; 309(7):C470-9. Lao DH, Esparza MC, Bremner SN, Banerjee I, Zhang J, Veevers J, Bradford WH, Gu Y, Dalton ND, Knowlton KU, Peterson KL, Lieber RL, Chen J. PMID: 26157009; PMCID: PMC4593772.
View in: PubMed Mentions: 8 Fields:
Translation:AnimalsCells - Mitochondrial reprogramming induced by CaMKIIδ mediates hypertrophy decompensation. Circ Res. 2015 Feb 27; 116(5):e28-39. Westenbrink BD, Ling H, Divakaruni AS, Gray CB, Zambon AC, Dalton ND, Peterson KL, Gu Y, Matkovich SJ, Murphy AN, Miyamoto S, Dorn GW, Heller Brown J. PMID: 25605649; PMCID: PMC4344921.
View in: PubMed Mentions: 31 Fields:
Translation:AnimalsCells - Discoidin domain receptor 2 germline gene deletion leads to altered heart structure and function in the mouse. Am J Physiol Heart Circ Physiol. 2014 Sep 01; 307(5):H773-81. Cowling RT, Yeo SJ, Kim IJ, Park JI, Gu Y, Dalton ND, Peterson KL, Greenberg BH. PMID: 24993042; PMCID: PMC4187391.
View in: PubMed Mentions: 19 Fields:
Translation:AnimalsCells - Intermittent hypoxia and hypercapnia induce pulmonary artery atherosclerosis and ventricular dysfunction in low density lipoprotein receptor deficient mice. J Appl Physiol (1985). 2013 Dec; 115(11):1694-704. Douglas RM, Bowden K, Pattison J, Peterson AB, Juliano J, Dalton ND, Gu Y, Alvarez E, Imamura T, Peterson KL, Witztum JL, Haddad GG, Li AC. PMID: 23990245; PMCID: PMC3882740.
View in: PubMed Mentions: 10 Fields:
Translation:Animals - Impaired exercise capacity and skeletal muscle function in a mouse model of pulmonary inflammation. J Appl Physiol (1985). 2013 May; 114(9):1340-50. Tang K, Murano G, Wagner H, Nogueira L, Wagner PD, Tang A, Dalton ND, Gu Y, Peterson KL, Breen EC. PMID: 23449936; PMCID: PMC3656431.
View in: PubMed Mentions: 14 Fields:
Translation:AnimalsCells - Ca2+/Calmodulin-dependent protein kinase II δ mediates myocardial ischemia/reperfusion injury through nuclear factor-κB. Circ Res. 2013 Mar 15; 112(6):935-44. Ling H, Gray CB, Zambon AC, Grimm M, Gu Y, Dalton N, Purcell NH, Peterson K, Brown JH. PMID: 23388157; PMCID: PMC3673710.
View in: PubMed Mentions: 91 Fields:
Translation:AnimalsCells - Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease. J Clin Invest. 2012 Apr; 122(4):1209-21. Sheikh F, Ouyang K, Campbell SG, Lyon RC, Chuang J, Fitzsimons D, Tangney J, Hidalgo CG, Chung CS, Cheng H, Dalton ND, Gu Y, Kasahara H, Ghassemian M, Omens JH, Peterson KL, Granzier HL, Moss RL, McCulloch AD, Chen J. PMID: 22426213; PMCID: PMC3314469.
View in: PubMed Mentions: 102 Fields:
Translation:AnimalsCells - β1 integrin gene excision in the adult murine cardiac myocyte causes defective mechanical and signaling responses. Am J Pathol. 2012 Mar; 180(3):952-962. Li R, Wu Y, Manso AM, Gu Y, Liao P, Israeli S, Yajima T, Nguyen U, Huang MS, Dalton ND, Peterson KL, Ross RS. PMID: 22248583; PMCID: PMC3349893.
View in: PubMed Mentions: 30 Fields:
Translation:AnimalsCells - Thymosin beta 4 is dispensable for murine cardiac development and function. Circ Res. 2012 Feb 03; 110(3):456-64. Banerjee I, Zhang J, Moore-Morris T, Lange S, Shen T, Dalton ND, Gu Y, Peterson KL, Evans SM, Chen J. PMID: 22158707; PMCID: PMC3739283.
View in: PubMed Mentions: 36 Fields:
Translation:Animals - Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function. J Clin Invest. 2011 Dec; 121(12):4640-54. Shen T, Aneas I, Sakabe N, Dirschinger RJ, Wang G, Smemo S, Westlund JM, Cheng H, Dalton N, Gu Y, Boogerd CJ, Cai CL, Peterson K, Chen J, Nobrega MA, Evans SM. PMID: 22080862; PMCID: PMC3223071.
View in: PubMed Mentions: 86 Fields:
Translation:HumansAnimalsCells - Absence of SOCS3 in the cardiomyocyte increases mortality in a gp130-dependent manner accompanied by contractile dysfunction and ventricular arrhythmias. Circulation. 2011 Dec 13; 124(24):2690-701. Yajima T, Murofushi Y, Zhou H, Park S, Housman J, Zhong ZH, Nakamura M, Machida M, Hwang KK, Gu Y, Dalton ND, Yajima T, Yasukawa H, Peterson KL, Knowlton KU. PMID: 22082679; PMCID: PMC3253669.
View in: PubMed Mentions: 27 Fields:
Translation:AnimalsCells - Increased infarct wall thickness by a bio-inert material is insufficient to prevent negative left ventricular remodeling after myocardial infarction. PLoS One. 2011; 6(6):e21571. Rane AA, Chuang JS, Shah A, Hu DP, Dalton ND, Gu Y, Peterson KL, Omens JH, Christman KL. PMID: 21731777; PMCID: PMC3121880.
View in: PubMed Mentions: 45 Fields:
Translation:Animals - Selective deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy. Hum Mol Genet. 2011 May 01; 20(9):1751-62. Cheng H, Zheng M, Peter AK, Kimura K, Li X, Ouyang K, Shen T, Cui L, Frank D, Dalton ND, Gu Y, Frey N, Peterson KL, Evans SM, Knowlton KU, Sheikh F, Chen J. PMID: 21303826; PMCID: PMC3071671.
View in: PubMed Mentions: 24 Fields:
Translation:HumansAnimals - Delta-sarcoglycan gene therapy halts progression of cardiac dysfunction, improves respiratory failure, and prolongs life in myopathic hamsters. Circ Heart Fail. 2011 Jan; 4(1):89-97. Hoshijima M, Hayashi T, Jeon YE, Fu Z, Gu Y, Dalton ND, Ellisman MH, Xiao X, Powell FL, Ross J. PMID: 21036890; PMCID: PMC3742303.
View in: PubMed Mentions: 10 Fields:
Translation:AnimalsCells - Urocortin 2 lowers blood pressure and reduces plasma catecholamine levels in mice with hyperadrenergic activity. Endocrinology. 2010 Oct; 151(10):4820-9. Gu Y, Zhang K, Biswas N, Friese RS, Lin DH, Mahata SK, Hoshijima M, O'Connor DT, Peterson KL, Brar BK. PMID: 20668031; PMCID: PMC2946150.
View in: PubMed Mentions: 2 Fields:
Translation:AnimalsCells - MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice. J Clin Invest. 2010 Aug; 120(8):2805-16. Zhang D, Contu R, Latronico MV, Zhang J, Zhang JL, Rizzi R, Catalucci D, Miyamoto S, Huang K, Ceci M, Gu Y, Dalton ND, Peterson KL, Guan KL, Brown JH, Chen J, Sonenberg N, Condorelli G. PMID: 20644257; PMCID: PMC2912201.
View in: PubMed Mentions: 211 Fields:
Translation:AnimalsCells - Loss of enigma homolog protein results in dilated cardiomyopathy. Circ Res. 2010 Aug 06; 107(3):348-56. Cheng H, Kimura K, Peter AK, Cui L, Ouyang K, Shen T, Liu Y, Gu Y, Dalton ND, Evans SM, Knowlton KU, Peterson KL, Chen J. PMID: 20538684; PMCID: PMC3684396.
View in: PubMed Mentions: 66 Fields:
Translation:AnimalsCells - Pulmonary artery pressure responses to increased cardiac output in chickens with raised metabolic rate. Comp Biochem Physiol A Mol Integr Physiol. 2010 Aug; 156(4):430-5. West JB, Fu Z, Gu Y, Wagner HE, Carr JA, Peterson KL. PMID: 20363353; PMCID: PMC2892207.
View in: PubMed Mentions: 2 Fields:
Translation:Animals - Nesprin 1 is critical for nuclear positioning and anchorage. Hum Mol Genet. 2010 Jan 15; 19(2):329-41. Zhang J, Felder A, Liu Y, Guo LT, Lange S, Dalton ND, Gu Y, Peterson KL, Mizisin AP, Shelton GD, Lieber RL, Chen J. PMID: 19864491; PMCID: PMC2796894.
View in: PubMed Mentions: 95 Fields:
Translation:HumansAnimalsCells - Global disturbances in autonomic function yield cardiovascular instability and hypertension in the chromogranin a null mouse. Endocrinology. 2009 Nov; 150(11):5027-35. Gayen JR, Gu Y, O'Connor DT, Mahata SK. PMID: 19819970; PMCID: PMC2775982.
View in: PubMed Mentions: 39 Fields:
Translation:Animals - Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest. 2009 May; 119(5):1230-40. Ling H, Zhang T, Pereira L, Means CK, Cheng H, Gu Y, Dalton ND, Peterson KL, Chen J, Bers D, Brown JH, Heller Brown J. PMID: 19381018; PMCID: PMC2673879.
View in: PubMed Mentions: 218 Fields:
Translation:AnimalsCells - Muscle-specific VEGF deficiency greatly reduces exercise endurance in mice. J Physiol. 2009 Apr 15; 587(Pt 8):1755-67. Olfert IM, Howlett RA, Tang K, Dalton ND, Gu Y, Peterson KL, Wagner PD, Breen EC. PMID: 19237429; PMCID: PMC2683962.
View in: PubMed Mentions: 74 Fields:
Translation:AnimalsCells - Impaired chronotropic response to exercise in mice lacking catecholamines in adrenergic cells. Ann N Y Acad Sci. 2008 Dec; 1148:297-301. Bao X, Liu F, Gu Y, Lu CM, Ziegler MG. PMID: 19120121.
View in: PubMed Mentions: Fields:
Translation:Animals - Cardiac-specific ablation of Cypher leads to a severe form of dilated cardiomyopathy with premature death. Hum Mol Genet. 2009 Feb 15; 18(4):701-13. Zheng M, Cheng H, Li X, Zhang J, Cui L, Ouyang K, Han L, Zhao T, Gu Y, Dalton ND, Bang ML, Peterson KL, Chen J. PMID: 19028670; PMCID: PMC2722217.
View in: PubMed Mentions: 63 Fields:
Translation:HumansAnimalsCells - An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice. J Clin Invest. 2008 Dec; 118(12):3870-80. Sheikh F, Raskin A, Chu PH, Lange S, Domenighetti AA, Zheng M, Liang X, Zhang T, Yajima T, Gu Y, Dalton ND, Mahata SK, Dorn GW, Brown JH, Heller-Brown J, Peterson KL, Omens JH, McCulloch AD, Chen J. PMID: 19033658; PMCID: PMC2575833.
View in: PubMed Mentions: 143 Fields:
Translation:AnimalsCells - Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart. J Clin Invest. 2008 Aug; 118(8):2758-70. Lim BK, Xiong D, Dorner A, Youn TJ, Yung A, Liu TI, Gu Y, Dalton ND, Wright AT, Evans SM, Chen J, Peterson KL, McCulloch AD, Yajima T, Knowlton KU. PMID: 18636119; PMCID: PMC2467382.
View in: PubMed Mentions: 67 Fields: - Syncoilin is required for generating maximum isometric stress in skeletal muscle but dispensable for muscle cytoarchitecture. Am J Physiol Cell Physiol. 2008 May; 294(5):C1175-82. Zhang J, Bang ML, Gokhin DS, Lu Y, Cui L, Li X, Gu Y, Dalton ND, Scimia MC, Peterson KL, Lieber RL, Chen J. PMID: 18367591; PMCID: PMC2749034.
View in: PubMed Mentions: 14 Fields:
Translation:AnimalsCells - Epinephrine is required for normal cardiovascular responses to stress in the phenylethanolamine N-methyltransferase knockout mouse. Circulation. 2007 Aug 28; 116(9):1024-31. Bao X, Lu CM, Liu F, Gu Y, Dalton ND, Zhu BQ, Foster E, Chen J, Karliner JS, Ross J, Simpson PC, Ziegler MG. PMID: 17698731.
View in: PubMed Mentions: 17 Fields:
Translation:Animals - alpha-E-catenin inactivation disrupts the cardiomyocyte adherens junction, resulting in cardiomyopathy and susceptibility to wall rupture. Circulation. 2006 Sep 05; 114(10):1046-55. Sheikh F, Chen Y, Chen Y, Liang X, Hirschy A, Stenbit AE, Gu Y, Dalton ND, Yajima T, Lu Y, Knowlton KU, Peterson KL, Perriard JC, Chen J. PMID: 16923756.
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Translation:AnimalsCells - Distinct roles of HF-1b/Sp4 in ventricular and neural crest cells lineages affect cardiac conduction system development. Dev Biol. 2006 Mar 15; 291(2):208-17. St Amand TR, Lu JT, Zamora M, Gu Y, Stricker J, Hoshijima M, Epstein JA, Ross JJ, Ruiz-Lozano P, Chien KR. PMID: 16430881.
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Translation:AnimalsCells - Gene transfer of a phospholamban-targeted antibody improves calcium handling and cardiac function in heart failure. Cardiovasc Res. 2005 Sep 01; 67(4):678-88. Dieterle T, Meyer M, Gu Y, Belke DD, Swanson E, Iwatate M, Hollander J, Peterson KL, Ross J, Dillmann WH. PMID: 15927173.
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Translation:AnimalsCells - Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog. J Clin Invest. 2005 Jul; 115(7):1942-52. Mahapatra NR, O'Connor DT, Vaingankar SM, Hikim AP, Mahata M, Ray S, Staite E, Wu H, Gu Y, Dalton N, Kennedy BP, Ziegler MG, Ross J, Mahata SK. PMID: 16007257; PMCID: PMC1159140.
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Translation:HumansAnimalsCells - Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats. J Clin Invest. 2004 Mar; 113(5):727-36. Iwanaga Y, Hoshijima M, Gu Y, Iwatate M, Dieterle T, Ikeda Y, Date MO, Chrast J, Matsuzaki M, Peterson KL, Chien KR, Ross J. PMID: 14991071; PMCID: PMC351313.
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Translation:AnimalsCells - A nitric oxide-releasing derivative of enalapril, NCX 899, prevents progressive cardiac dysfunction and remodeling in hamsters with heart failure. FASEB J. 2004 Mar; 18(3):587-8. Iwanaga Y, Gu Y, Dieterle T, Presotto C, Del Soldato P, Peterson KL, Ongini E, Condorelli G, Ross J. PMID: 14734637.
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Translation:Animals - Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice. Proc Natl Acad Sci U S A. 2002 Aug 20; 99(17):11375-80. Zhao YY, Liu Y, Stan RV, Fan L, Gu Y, Dalton N, Chu PH, Peterson K, Ross J, Chien KR. PMID: 12177436; PMCID: PMC123264.
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Translation:Animals - Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery. Nat Med. 2002 Aug; 8(8):864-71. Hoshijima M, Ikeda Y, Iwanaga Y, Minamisawa S, Date MO, Gu Y, Iwatate M, Li M, Wang L, Wilson JM, Wang Y, Ross J, Chien KR. PMID: 12134142.
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Translation:HumansAnimalsCells - Restoration of deficient membrane proteins in the cardiomyopathic hamster by in vivo cardiac gene transfer. Circulation. 2002 Jan 29; 105(4):502-8. Ikeda Y, Gu Y, Iwanaga Y, Hoshijima M, Oh SS, Giordano FJ, Chen J, Nigro V, Peterson KL, Chien KR, Ross J. PMID: 11815435.
View in: PubMed Mentions: 23 Fields:
Translation:AnimalsCells - The cardiac-specific nuclear delta(B) isoform of Ca2+/calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity. J Biol Chem. 2002 Jan 11; 277(2):1261-7. Zhang T, Johnson EN, Gu Y, Morissette MR, Sah VP, Gigena MS, Belke DD, Dillmann WH, Rogers TB, Schulman H, Ross J, Brown JH. PMID: 11694533.
View in: PubMed Mentions: 91 Fields:
Translation:AnimalsCells
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