Luke Fischer • UCSF Profiles (original) (raw)

  1. Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers. Alzheimers Dement. 2025 Oct; 21(10):e70734. Fischer DL, Grinberg LT, Ahrendsen JT, Beach TG, Bieniek KF, Castellani RJ, Chkheidze R, Cobos I, Cohen M, Crary JF, Dickson DW, Dugger BN, Dunlop SR, Farrell K, Ghetti B, Haeri M, Harrison W, Head E, Hiniker A, Huang EJ, Huttner A, Jamshidi P, Kapasi A, Keene CD, Kofler J, Latimer CS, McKee AC, Mente K, Miller MB, Montine TJ, Morris M, Murray ME, Nelson PT, Newell KL, Perrin RJ, Ramani B, Reichard RR, Roy S, Schlachetzki JCM, Seeley WW, Serrano GE, Spina S, Teich AF, Wang SJ, Wisniewski T, Lee EB. PMID: 41085158; PMCID: PMC12519528.
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  2. Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline. Ann Neurol. 2025 Nov; 98(5):1014-1026. Wood Alexander M, Fischer DL, VandeVrede L, Nichols E, Yu L, Pike JR, Swardfager W, Wu CY, Masellis M, Galea LAM, Zukotynski K, Einstein G, Black SE, Barnes LL, Schneider JA, Arvanitakis Z, Casaletto KB, Rabin JS. PMID: 40646704; PMCID: PMC12341763.
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    Translation:HumansCells
  3. BDNF Val66Met polymorphism moderates associations between physical activity and neurocognitive outcomes in older adults. Alzheimers Dement (N Y). 2025 Apr-Jun; 11(2):e70106. Cadwallader CJ, VandeBunte AM, Fischer DL, Chen C, Diaz VE, Lee SY, Chan B, Lario-Lago A, Rojas JC, Ramos EM, Rexach JE, Yokoyama JS, Kramer JH, Paolillo EW, Saloner R, Casaletto KB. PMID: 40547329; PMCID: PMC12178939.
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  4. Distinct subcellular localization of tau and alpha-synuclein in lewy body disease. Acta Neuropathol Commun. 2025 01 21; 13(1):14. Fischer DL, Menard M, Abdelaziz OZ, Kanaan NM, Cobbs VG, Kennedy RE, Serrano GE, Beach TG, Volpicelli-Daley LA. PMID: 39838428; PMCID: PMC11752823.
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    Translation:HumansCells
  5. Clinicopathological correlation of cerebrospinal fluid alpha-synuclein seed amplification assay in a behavioral neurology autopsy cohort. Alzheimers Dement. 2024 05; 20(5):3334-3341. Samudra N, Fischer DL, Lenio S, Lario Lago A, Ljubenkov PA, Rojas JC, Seeley WW, Spina S, Staffaroni AM, Tablante J, Wekselman F, Lamoureux J, Concha-Marambio L, Grinberg LT, Boxer AL, VandeVrede L. PMID: 38539061; PMCID: PMC11095442.
    View in: PubMed Mentions: 17 Fields:
    Translation:Humans
  6. A Precision Medicine Approach to Dementia Care: Syndrome, Etiology, and Copathology. Pract Neurol (Fort Wash Pa). 2023 Jul; 2023:17-22. Fischer DL, Seeley WW. PMID: 37539046; PMCID: PMC10399644.
    View in: PubMed Mentions: 2
  7. BDNF rs10501087, rs1491850 and rs11030094 polymorphisms associated with delayed progression in early-stage Parkinson's disease. Front Neurol. 2022; 13:1053591. Fischer DL, Auinger P, Goudreau JL, Paumier KL, Cole-Strauss A, Kemp CJ, Lipton JW, Sortwell CE. PMID: 36468063; PMCID: PMC9713476.
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  8. BDNF rs6265 Genotype Influences Outcomes of Pharmacotherapy and Subthalamic Nucleus Deep Brain Stimulation in Early-Stage Parkinson's Disease. Neuromodulation. 2022 Aug; 25(6):846-853. Sortwell CE, Hacker ML, Fischer DL, Konrad PE, Davis TL, Neimat JS, Wang L, Song Y, Mattingly ZR, Cole-Strauss A, Lipton JW, Charles PD. PMID: 34288271; PMCID: PMC8770717.
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    Translation:Humans
  9. BDNF rs6265 Variant Alters Outcomes with Levodopa in Early-Stage Parkinson's Disease. Neurotherapeutics. 2020 10; 17(4):1785-1795. Fischer DL, Auinger P, Goudreau JL, Cole-Strauss A, Kieburtz K, Elm JJ, Hacker ML, Charles PD, Lipton JW, Pickut BA, Sortwell CE. PMID: 33215284; PMCID: PMC7851242.
    View in: PubMed Mentions: 10 Fields:
    Translation:Humans
  10. The BDNF Val66Met polymorphism (rs6265) enhances dopamine neuron graft efficacy and side-effect liability in rs6265 knock-in rats. Neurobiol Dis. 2021 01; 148:105175. Mercado NM, Stancati JA, Sortwell CE, Mueller RL, Boezwinkle SA, Duffy MF, Fischer DL, Sandoval IM, Manfredsson FP, Collier TJ, Steece-Collier K. PMID: 33188920; PMCID: PMC7855552.
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    Translation:AnimalsCells
  11. External Ventricular Drain Placement Accuracy and Safety When Done by Midlevel Practitioners. Neurosurgery. 2019 01 01; 84(1):235-241. Ellens NR, Fischer DL, Meldau JE, Schroeder BA, Patra SE. PMID: 29618119.
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    Translation:Humans
  12. BDNF provides many routes toward STN DBS-mediated disease modification. Mov Disord. 2019 01; 34(1):22-34. Fischer DL, Sortwell CE. PMID: 30440081; PMCID: PMC6587505.
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    Translation:Humans
  13. Quality Over Quantity: Advantages of Using Alpha-Synuclein Preformed Fibril Triggered Synucleinopathy to Model Idiopathic Parkinson's Disease. Front Neurosci. 2018; 12:621. Duffy MF, Collier TJ, Patterson JR, Kemp CJ, Fischer DL, Stoll AC, Sortwell CE. PMID: 30233303; PMCID: PMC6132025.
    View in: PubMed Mentions: 32
  14. Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration. J Neuroinflammation. 2018 May 29; 15(1):169. Duffy MF, Collier TJ, Patterson JR, Kemp CJ, Luk KC, Tansey MG, Paumier KL, Kanaan NM, Fischer DL, Polinski NK, Barth OL, Howe JW, Vaikath NN, Majbour NK, El-Agnaf OMA, Sortwell CE. PMID: 29843738; PMCID: PMC5975483.
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  15. Bdnf variant is associated with milder motor symptom severity in early-stage Parkinson's disease. Parkinsonism Relat Disord. 2018 08; 53:70-75. Fischer DL, Auinger P, Goudreau JL, Paumier KL, Cole-Strauss A, Kemp CJ, Lipton JW, Sortwell CE. PMID: 29759928.
    View in: PubMed Mentions: 10 Fields:
    Translation:Humans
  16. Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration. J Neuroinflammation. 2018 May 01; 15(1):129. Duffy MF, Collier TJ, Patterson JR, Kemp CJ, Luk KC, Tansey MG, Paumier KL, Kanaan NM, Fischer DL, Polinski NK, Barth OL, Howe JW, Vaikath NN, Majbour NK, El-Agnaf OMA, Sortwell CE. PMID: 29716614; PMCID: PMC5930695.
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    Translation:AnimalsCells
  17. Subthalamic Nucleus Deep Brain Stimulation Does Not Modify the Functional Deficits or Axonopathy Induced by Nigrostriatal α-Synuclein Overexpression. Sci Rep. 2017 11 27; 7(1):16356. Fischer DL, Manfredsson FP, Kemp CJ, Cole-Strauss A, Lipton JW, Duffy MF, Polinski NK, Steece-Collier K, Collier TJ, Gombash SE, Buhlinger DJ, Sortwell CE. PMID: 29180681; PMCID: PMC5703955.
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    Translation:AnimalsCells
  18. Can STN DBS protect both nigral somata and innervation of the striatum? Ann Neurol. 2017 11; 82(5):855. Fischer DL, Manfredsson FP, Sortwell CE. PMID: 28985650.
    View in: PubMed Mentions: 1 Fields:
    Translation:Animals
  19. Subthalamic Nucleus Deep Brain Stimulation Employs trkB Signaling for Neuroprotection and Functional Restoration. J Neurosci. 2017 07 12; 37(28):6786-6796. Fischer DL, Kemp CJ, Cole-Strauss A, Polinski NK, Paumier KL, Lipton JW, Steece-Collier K, Collier TJ, Buhlinger DJ, Sortwell CE. PMID: 28607168; PMCID: PMC5508259.
    View in: PubMed Mentions: 26 Fields:
    Translation:AnimalsCells
  20. Alpha-Synuclein mRNA Is Not Increased in Sporadic PD and Alpha-Synuclein Accumulation Does Not Block GDNF Signaling in Parkinson's Disease and Disease Models. Mol Ther. 2017 10 04; 25(10):2231-2235. Su X, Fischer DL, Li X, Bankiewicz K, Sortwell CE, Federoff HJ. PMID: 28522034; PMCID: PMC5628770.
    View in: PubMed Mentions: 29 Fields:
    Translation:Humans
  21. Impact of age and vector construct on striatal and nigral transgene expression. Mol Ther Methods Clin Dev. 2016; 3:16082. Polinski NK, Manfredsson FP, Benskey MJ, Fischer DL, Kemp CJ, Steece-Collier K, Sandoval IM, Paumier KL, Sortwell CE. PMID: 27933309; PMCID: PMC5142515.
    View in: PubMed Mentions: 18
  22. Viral Vector-Based Modeling of Neurodegenerative Disorders: Parkinson's Disease. Methods Mol Biol. 2016; 1382:367-82. Fischer DL, Gombash SE, Kemp CJ, Manfredsson FP, Polinski NK, Duffy MF, Sortwell CE. PMID: 26611600.
    View in: PubMed Mentions: 13 Fields:
    Translation:AnimalsCells
  23. High-Frequency Stimulation of the Rat Entopeduncular Nucleus Does Not Provide Functional or Morphological Neuroprotection from 6-Hydroxydopamine. PLoS One. 2015; 10(7):e0133957. Fischer DL, Collier TJ, Cole-Strauss A, Wohlgenant SL, Lipton JW, Steece-Collier K, Manfredsson FP, Kemp CJ, Sortwell CE. PMID: 26222442; PMCID: PMC4519335.
    View in: PubMed Mentions: 6 Fields:
    Translation:AnimalsCells
  24. Neuroprotective potential of pleiotrophin overexpression in the striatonigral pathway compared with overexpression in both the striatonigral and nigrostriatal pathways. Gene Ther. 2014 Jul; 21(7):682-93. Gombash SE, Manfredsson FP, Mandel RJ, Collier TJ, Fischer DL, Kemp CJ, Kuhn NM, Wohlgenant SL, Fleming SM, Sortwell CE. PMID: 24807806; PMCID: PMC4326069.
    View in: PubMed Mentions: 21 Fields:
    Translation:AnimalsCells

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This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.

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