Search Results - DZNEPUB (original) (raw)

DDC: 100

Type: journal [print, online]

Country: Romania

DDC: 610

Type: journal [online]

Country: Netherlands

[DZNE-2024-01157] Contribution to a book

Rusakov, D. ; Zeug, A. ; Unichenko, P. ; et al
Quantitative Optical Analysis of Astrocytic Ca2+ Signaling

2024Fluorescence Imaging of the Brain / Rusakov, Dmitri (Editor) ; New York, NY : Springer US, 2024, Chapter 2 ; ISSN: 0893-2336=1940-6045 ; ISBN: 978-1-0716-4010-4=978-1-0716-4011-1 ; doi:10.1007/978-1-0716-4011-1 New York, NY : Springer US, Neuromethods 209, 21 - 57 (2024) [10.1007/978-1-0716-4011-1_2]2024

Ca2+ signaling of astrocytes plays a central role in the physiology and pathophysiology of these non-neuronal cells in the brain. Decades of research have revealed the heterogeneity of astrocytic Ca2+ signals and how they are triggered, how they propagate, what mechanisms sustain them, and what their downstream effects are on the cellular, network, and behavioral level [...]

[DZNE-2024-01156] Contribution to a book

Rusakov, D. ; Cangalaya, C. ; Dityatev, A.
Synaptic Photodamage and Its Application to Study Microglia–Synapse Interactions In Vivo

2024Fluorescence Imaging of the Brain / Rusakov, Dmitri (Editor) ; New York, NY : Springer US, 2024, Chapter 5 ; ISSN: 0893-2336=1940-6045 ; ISBN: 978-1-0716-4010-4=978-1-0716-4011-1 ; doi:10.1007/978-1-0716-4011-1 New York, NY : Springer US, Neuromethods 209, 111 - 126 (2024) [10.1007/978-1-0716-4011-1_5]2024

Microglia appeared as the major player in the remodeling of synapses under physiological and pathophysiological conditions, in particular during development, forgetting, and neuroinflammation. In this chapter, we describe in vivo two-photon photodamage of single synapses to induce microglia–synapse interactions. [...]

[DZNE-2024-01152] Journal Article

Olma, M. C. ; Tütüncü, S. ; Hansen, K. ; et al
Timing of oral anticoagulation in atrial fibrillation patients after acute ischaemic stroke and outcome after 3 months: results of the multicentre Berlin Atrial Fibrillation Registry.

Oral anticoagulation (OAC) is key in stroke prevention in patients with atrial fibrillation (AF) but there is uncertainty regarding the optimal timing of OAC (re)initiation after stroke, as recent large randomised controlled trials have methodological weaknesses and excluded stroke patients on therapeutic anticoagulation at stroke onset as well as patients started on a vitamin K antagonist after stroke. The '1-3-6-12 days rule', based on expert consensus and referring to stroke severity, was used in clinical practice to initiate OAC after acute ischaemic stroke or transient ischaemic attack (TIA) since publication in 2013.We retrospectively assessed whether compliance to the '1-3-6-12 days rule' was associated with the composite endpoint (recurrent stroke, systemic embolism, myocardial infarction, major bleeding or all-cause death).Among 708 registry patients with known AF before stroke and hospitalisation within 72 hours after stroke, 432 were anticoagulated at stroke onset. [...]

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