Accumulating active p53 in the nucleus by inhibition of nuclear export: a novel strategy to promote the p53 tumor suppressor function - PubMed (original) (raw)

Review

. 1999 Dec 15;253(2):315-24.

doi: 10.1006/excr.1999.4672.

Affiliations

• PMID: 10585254
• DOI: 10.1006/excr.1999.4672

Review

Accumulating active p53 in the nucleus by inhibition of nuclear export: a novel strategy to promote the p53 tumor suppressor function

S Laín et al. Exp Cell Res. 1999.

No abstract available

PubMed Disclaimer

Similar articles

• Involvement of nuclear export in human papillomavirus type 18 E6-mediated ubiquitination and degradation of p53.
  Stewart D, Ghosh A, Matlashewski G. Stewart D, et al. J Virol. 2005 Jul;79(14):8773-83. doi: 10.1128/JVI.79.14.8773-8783.2005. J Virol. 2005. PMID: 15994771 Free PMC article.
• Inhibition of Crm1-p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ation.
  Kanai M, Hanashiro K, Kim SH, Hanai S, Boulares AH, Miwa M, Fukasawa K. Kanai M, et al. Nat Cell Biol. 2007 Oct;9(10):1175-83. doi: 10.1038/ncb1638. Epub 2007 Sep 23. Nat Cell Biol. 2007. PMID: 17891139
• p53 stabilization: the importance of nuclear import.
  Marine JC. Marine JC. Cell Death Differ. 2010 Feb;17(2):191-2. doi: 10.1038/cdd.2009.183. Cell Death Differ. 2010. PMID: 20062067 No abstract available.
• Nuclear tumor suppressors in space and time.
  Barbie DA, Conlan LA, Kennedy BK. Barbie DA, et al. Trends Cell Biol. 2005 Jul;15(7):378-85. doi: 10.1016/j.tcb.2005.05.005. Trends Cell Biol. 2005. PMID: 15936946 Review.
• Mutant p53: "gain of function" through perturbation of nuclear structure and function?
  Deppert W, Göhler T, Koga H, Kim E. Deppert W, et al. J Cell Biochem Suppl. 2000;Suppl 35:115-22. J Cell Biochem Suppl. 2000. PMID: 11389540 Review.

Cited by

• p53 and MDM2 are involved in the regulation of osteocalcin gene expression.
  Chen H, Kolman K, Lanciloti N, Nerney M, Hays E, Robson C, Chandar N. Chen H, et al. Exp Cell Res. 2012 May 1;318(8):867-76. doi: 10.1016/j.yexcr.2012.02.022. Epub 2012 Mar 3. Exp Cell Res. 2012. PMID: 22405968 Free PMC article.
• Identification of three functions of the adenovirus e4orf6 protein that mediate p53 degradation by the E4orf6-E1B55K complex.
  Querido E, Morrison MR, Chu-Pham-Dang H, Thirlwell SW, Boivin D, Branton PE. Querido E, et al. J Virol. 2001 Jan;75(2):699-709. doi: 10.1128/JVI.75.2.699-709.2001. J Virol. 2001. PMID: 11134283 Free PMC article.
• Plasmablastic Lymphoma. A State-of-the-Art Review: Part 2-Focus on Therapy.
  Bibas M. Bibas M. Mediterr J Hematol Infect Dis. 2024 Mar 1;16(1):e2024015. doi: 10.4084/MJHID.2024.015. eCollection 2024. Mediterr J Hematol Infect Dis. 2024. PMID: 38468838 Free PMC article. Review.
• Chemotherapeutic sensitization of leptomycin B resistant lung cancer cells by pretreatment with doxorubicin.
  Lu C, Shao C, Cobos E, Singh KP, Gao W. Lu C, et al. PLoS One. 2012;7(3):e32895. doi: 10.1371/journal.pone.0032895. Epub 2012 Mar 7. PLoS One. 2012. PMID: 22412944 Free PMC article.
• Proteomic analysis of the mammalian nuclear pore complex.
  Cronshaw JM, Krutchinsky AN, Zhang W, Chait BT, Matunis MJ. Cronshaw JM, et al. J Cell Biol. 2002 Sep 2;158(5):915-27. doi: 10.1083/jcb.200206106. Epub 2002 Aug 26. J Cell Biol. 2002. PMID: 12196509 Free PMC article.

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Elsevier Science

• Other Literature Sources

  • The Lens - Patent Citations Database

• Research Materials

  • NCI CPTC Antibody Characterization Program

• Miscellaneous

  • NCI CPTAC Assay Portal