Stem cell medicine encounters the immune system - PubMed (original) (raw)
Review
doi: 10.1038/nri934.
Affiliations
- PMID: 12415309
- DOI: 10.1038/nri934
Review
Stem cell medicine encounters the immune system
J Andrew Bradley et al. Nat Rev Immunol. 2002 Nov.
Abstract
Recent progress in deriving human embryonic stem (hES) cells and defining their capacity to differentiate has inspired hope that they could become a source of replacement cells for damaged or diseased tissues. We review the immunological barriers to transplanting hES cells and consider several potential solutions, including stem-cell banking, modification of the immunogenicity of donor cells and induction of tolerance to the graft. We evaluate the probable efficacy of these approaches with a view to facilitating the use of hES cells in clinical practice.
Similar articles
- [ABO incompatibility and non myeloablative allogeneic stem cell transplantation].
Malfuson JV, Hicheri Y, Bonin P, Rodet M, Boccaccio C, Pautas C, Kuentz M, Cordonnier C, Noizat-Pirenne F, Maury S. Malfuson JV, et al. Transfus Clin Biol. 2007 Aug;14(3):327-33. doi: 10.1016/j.tracli.2007.03.002. Epub 2007 Apr 25. Transfus Clin Biol. 2007. PMID: 17462938 Review. French. - ABO-histo blood group incompatibility in hematopoietic stem cell and solid organ transplantation.
Stussi G, Halter J, Schanz U, Seebach JD. Stussi G, et al. Transfus Apher Sci. 2006 Aug;35(1):59-69. doi: 10.1016/j.transci.2006.05.009. Epub 2006 Aug 28. Transfus Apher Sci. 2006. PMID: 16935028 Review. - Xenotransplantation and ABO incompatible transplantation: the similarities they share.
Galili U. Galili U. Transfus Apher Sci. 2006 Aug;35(1):45-58. doi: 10.1016/j.transci.2006.05.007. Epub 2006 Aug 14. Transfus Apher Sci. 2006. PMID: 16905361 Review. - Overcoming immunologic incompatibility: transplanting the difficult to transplant patient.
Crew RJ, Ratner LE. Crew RJ, et al. Semin Dial. 2005 Nov-Dec;18(6):474-81. doi: 10.1111/j.1525-139X.2005.00092.x. Semin Dial. 2005. PMID: 16398709 Review. - Current challenges in human embryonic stem cell research: directed differentiation and transplantation tolerance.
Ponsaerts P, van Tendeloo VF, Jorens PG, Berneman ZN, van Bockstaele DR. Ponsaerts P, et al. J Biol Regul Homeost Agents. 2004 Jul-Dec;18(3-4):347-51. J Biol Regul Homeost Agents. 2004. PMID: 15786703 Review.
Cited by
- Monoclonal antibody-mediated immunosuppression enables long-term survival of transplanted human neural stem cells in mouse brain.
McGinley LM, Chen KS, Mason SN, Rigan DM, Kwentus JF, Hayes JM, Glass ED, Reynolds EL, Murphy GG, Feldman EL. McGinley LM, et al. Clin Transl Med. 2022 Sep;12(9):e1046. doi: 10.1002/ctm2.1046. Clin Transl Med. 2022. PMID: 36101963 Free PMC article. - Neurodegeneration and cell replacement.
Ormerod BK, Palmer TD, Caldwell MA. Ormerod BK, et al. Philos Trans R Soc Lond B Biol Sci. 2008 Jan 12;363(1489):153-70. doi: 10.1098/rstb.2006.2018. Philos Trans R Soc Lond B Biol Sci. 2008. PMID: 17331894 Free PMC article. Review. - Derivation and long-term culture of human parthenogenetic embryonic stem cells using human foreskin feeders.
Lu Z, Zhu W, Yu Y, Jin D, Guan Y, Yao R, Zhang YA, Zhang Y, Zhou Q. Lu Z, et al. J Assist Reprod Genet. 2010 Jun;27(6):285-91. doi: 10.1007/s10815-010-9408-5. J Assist Reprod Genet. 2010. PMID: 20393797 Free PMC article. - Death and inflammation following somatic cell transplantation.
Copland IB, Galipeau J. Copland IB, et al. Semin Immunopathol. 2011 Nov;33(6):535-50. doi: 10.1007/s00281-011-0274-8. Epub 2011 May 1. Semin Immunopathol. 2011. PMID: 21533908 Review. - Comparison of immunological characteristics of mesenchymal stem cells derived from human embryonic stem cells and bone marrow.
Fu X, Chen Y, Xie FN, Dong P, Liu WB, Cao Y, Zhang WJ, Xiao R. Fu X, et al. Tissue Eng Part A. 2015 Feb;21(3-4):616-26. doi: 10.1089/ten.TEA.2013.0651. Epub 2015 Jan 8. Tissue Eng Part A. 2015. PMID: 25256849 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical