The Proteome Analysis database: a tool for the in silico analysis of whole proteomes - PubMed (original) (raw)

The Proteome Analysis database: a tool for the in silico analysis of whole proteomes

Manuela Pruess et al. Nucleic Acids Res. 2003.

Abstract

The Proteome Analysis database (http://www.ebi.ac.uk/proteome/) has been developed by the Sequence Database Group at EBI utilizing existing resources and providing comparative analysis of the predicted protein coding sequences of the complete genomes of bacteria, archeae and eukaryotes. Three main projects are used, InterPro, CluSTr and GO Slim, to give an overview on families, domains, sites, and functions of the proteins from each of the complete genomes. Complete proteome analysis is available for a total of 89 proteome sets. A specifically designed application enables InterPro proteome comparisons for any one proteome against any other one or more of the proteomes in the database.

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Figures

Figure 1

Analysis of full-length proteins (fragments excluded): (a) _Homo sapiens_—average protein length: 469 amino acid residues; size range: 3–34 350 amino acid residues. (b) _Mus musculus_—average protein length: 416 amino acid residues; size range: 10–7389 amino acid residues.

Figure 2

Part of the top level proteome analysis page for Homo sapiens.

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