Epoxomicin, a new antitumor agent of microbial origin - PubMed (original) (raw)

Comparative Study

. 1992 Nov;45(11):1746-52.

doi: 10.7164/antibiotics.45.1746.

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• PMID: 1468981
• DOI: 10.7164/antibiotics.45.1746

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Comparative Study

Epoxomicin, a new antitumor agent of microbial origin

M Hanada et al. J Antibiot (Tokyo). 1992 Nov.

Free article

Abstract

An actinomycete strain No. Q996-17 produced a novel compound, epoxomicin, which exhibited in vivo antitumor activity against B16 melanoma. Structural studies indicated that it is a new member of the epoxy-beta-aminoketone group, and is closely related to eponemycin.

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