A genetic signature of interspecies variations in gene expression - PubMed (original) (raw)
Comparative Study
doi: 10.1038/ng1819. Epub 2006 Jun 18.
Affiliations
- PMID: 16783381
- DOI: 10.1038/ng1819
Comparative Study
A genetic signature of interspecies variations in gene expression
Itay Tirosh et al. Nat Genet. 2006 Jul.
Abstract
Phenotypic diversity is generated through changes in gene structure or gene regulation. The availability of full genomic sequences allows for the analysis of gene sequence evolution. In contrast, little is known about the principles driving the evolution of gene expression. Here we describe the differential transcriptional response of four closely related yeast species to a variety of environmental stresses. Genes containing a TATA box in their promoters show an increased interspecies variability in expression, independent of their functional association. Examining additional data sets, we find that this enhanced expression divergence of TATA-containing genes is consistent across all eukaryotes studied to date, including nematodes, fruit flies, plants and mammals. TATA-dependent regulation may enhance the sensitivity of gene expression to genetic perturbations, thus facilitating expression divergence at particular genetic loci.
Similar articles
- A yeast hybrid provides insight into the evolution of gene expression regulation.
Tirosh I, Reikhav S, Levy AA, Barkai N. Tirosh I, et al. Science. 2009 May 1;324(5927):659-62. doi: 10.1126/science.1169766. Science. 2009. PMID: 19407207 - Genetic properties influencing the evolvability of gene expression.
Landry CR, Lemos B, Rifkin SA, Dickinson WJ, Hartl DL. Landry CR, et al. Science. 2007 Jul 6;317(5834):118-21. doi: 10.1126/science.1140247. Epub 2007 May 24. Science. 2007. PMID: 17525304 - Rate of promoter class turn-over in yeast evolution.
Bazykin GA, Kondrashov AS. Bazykin GA, et al. BMC Evol Biol. 2006 Feb 10;6:14. doi: 10.1186/1471-2148-6-14. BMC Evol Biol. 2006. PMID: 16472383 Free PMC article. - Evolution of primate gene expression.
Khaitovich P, Enard W, Lachmann M, Pääbo S. Khaitovich P, et al. Nat Rev Genet. 2006 Sep;7(9):693-702. doi: 10.1038/nrg1940. Nat Rev Genet. 2006. PMID: 16921347 Review. - Expression divergence between duplicate genes.
Li WH, Yang J, Gu X. Li WH, et al. Trends Genet. 2005 Nov;21(11):602-7. doi: 10.1016/j.tig.2005.08.006. Epub 2005 Sep 2. Trends Genet. 2005. PMID: 16140417 Review.
Cited by
- Promoters Constrain Evolution of Expression Levels of Essential Genes in Escherichia coli.
Tsuru S, Hatanaka N, Furusawa C. Tsuru S, et al. Mol Biol Evol. 2024 Sep 4;41(9):msae185. doi: 10.1093/molbev/msae185. Mol Biol Evol. 2024. PMID: 39219319 Free PMC article. - Functional Clustering of Metabolically Related Genes Is Conserved across Dikarya.
Cittadino GM, Andrews J, Purewal H, Estanislao Acuña Avila P, Arnone JT. Cittadino GM, et al. J Fungi (Basel). 2023 Apr 28;9(5):523. doi: 10.3390/jof9050523. J Fungi (Basel). 2023. PMID: 37233234 Free PMC article. Review. - On the Role of TATA Boxes and TATA-Binding Protein in Arabidopsis thaliana.
Savinkova LK, Sharypova EB, Kolchanov NA. Savinkova LK, et al. Plants (Basel). 2023 Feb 22;12(5):1000. doi: 10.3390/plants12051000. Plants (Basel). 2023. PMID: 36903861 Free PMC article. Review. - Gene expression variability across cells and species shapes the relationship between renal resident macrophages and infiltrated macrophages.
Ji X, Cai J, Liang L, Shi T, Liu J. Ji X, et al. BMC Bioinformatics. 2023 Mar 1;24(1):72. doi: 10.1186/s12859-023-05198-z. BMC Bioinformatics. 2023. PMID: 36858955 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases