Promises, facts and challenges for carbon nanotubes in imaging and therapeutics - PubMed (original) (raw)

Promises, facts and challenges for carbon nanotubes in imaging and therapeutics

K Kostarelos et al. Nat Nanotechnol. 2009 Oct.

Abstract

The use of carbon nanotubes in medicine is now at the crossroads between a proof-of-principle concept and an established preclinical candidate for a variety of therapeutic and diagnostic applications. Progress towards clinical trials will depend on the outcomes of efficacy and toxicology studies, which will provide the necessary risk-to-benefit assessments for carbon-nanotube-based materials. Here we focus on carbon nanotubes that have been studied in preclinical animal models, and draw attention to the promises, facts and challenges of these materials as they transition from research to the clinical phase. We address common questions regarding the use of carbon nanotubes in disease imaging and therapy, and highlight the opportunities and challenges ahead.

PubMed Disclaimer

Comment in

References

    1. Am J Respir Cell Mol Biol. 2009 Mar;40(3):349-58 -PubMed
    1. Toxicol Lett. 2008 Oct 1;181(3):182-9 -PubMed
    1. Cancer. 2007 Dec 15;110(12):2654-65 -PubMed
    1. Nano Res. 2009 Feb 1;2(2):85-120 -PubMed
    1. Chem Commun (Camb). 2008 Jan 28;(4):459-61 -PubMed

MeSH terms

Substances

LinkOut - more resources